Li YM - Search Results

1

Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors.

Fan X, Matsui W, Khaki L, Stearns D, Chun J, Li YM, Eberhart CG. Fan X, et al. Among authors: li ym. Cancer Res. 2006 Aug 1;66(15):7445-52. doi: 10.1158/0008-5472.CAN-06-0858. Cancer Res. 2006. PMID: 16885340

2

Ligand-dependent Notch signaling is involved in tumor initiation and tumor maintenance in pancreatic cancer.

Mullendore ME, Koorstra JB, Li YM, Offerhaus GJ, Fan X, Henderson CM, Matsui W, Eberhart CG, Maitra A, Feldmann G. Mullendore ME, et al. Among authors: li ym. Clin Cancer Res. 2009 Apr 1;15(7):2291-301. doi: 10.1158/1078-0432.CCR-08-2004. Epub 2009 Mar 3. Clin Cancer Res. 2009. PMID: 19258443 Free PMC article.

3

NOTCH pathway blockade depletes CD133-positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts.

Fan X, Khaki L, Zhu TS, Soules ME, Talsma CE, Gul N, Koh C, Zhang J, Li YM, Maciaczyk J, Nikkhah G, Dimeco F, Piccirillo S, Vescovi AL, Eberhart CG. Fan X, et al. Among authors: li ym. Stem Cells. 2010 Jan;28(1):5-16. doi: 10.1002/stem.254. Stem Cells. 2010. PMID: 19904829 Free PMC article.

4

Stereo-controlled synthesis of novel photoreactive gamma-secretase inhibitors.

Yang G, Yin YI, Chun J, Shelton CC, Ouerfelli O, Li YM. Yang G, et al. Among authors: li ym. Bioorg Med Chem Lett. 2009 Feb 1;19(3):922-5. doi: 10.1016/j.bmcl.2008.11.117. Epub 2008 Dec 7. Bioorg Med Chem Lett. 2009. PMID: 19097779 Free PMC article.

5

Stereoselective synthesis of photoreactive peptidomimetic gamma-secretase inhibitors.

Chun J, Yin YI, Yang G, Tarassishin L, Li YM. Chun J, et al. Among authors: li ym. J Org Chem. 2004 Oct 15;69(21):7344-7. doi: 10.1021/jo0486948. J Org Chem. 2004. PMID: 15471490

6

gamma-Secretase inhibitors abrogate oxaliplatin-induced activation of the Notch-1 signaling pathway in colon cancer cells resulting in enhanced chemosensitivity.

Meng RD, Shelton CC, Li YM, Qin LX, Notterman D, Paty PB, Schwartz GK. Meng RD, et al. Among authors: li ym. Cancer Res. 2009 Jan 15;69(2):573-82. doi: 10.1158/0008-5472.CAN-08-2088. Cancer Res. 2009. PMID: 19147571 Free PMC article.

7

Increased expression of PS1 is sufficient to elevate the level and activity of γ-secretase in vivo.

Li T, Li YM, Ahn K, Price DL, Sisodia SS, Wong PC. Li T, et al. Among authors: li ym. PLoS One. 2011;6(11):e28179. doi: 10.1371/journal.pone.0028179. Epub 2011 Nov 29. PLoS One. 2011. PMID: 22140537 Free PMC article.

8

Imaging of Cancer γ-Secretase Activity Using an Inhibitor-Based PET Probe.

Nie P, Kalidindi T, Nagle VL, Wu X, Li T, Liao GP, Frost G, Henry KE, Punzalan B, Carter LM, Lewis JS, Pillarsetty NVK, Li YM. Nie P, et al. Among authors: li t, li ym. Clin Cancer Res. 2021 Nov 15;27(22):6145-6155. doi: 10.1158/1078-0432.CCR-21-0940. Epub 2021 Sep 2. Clin Cancer Res. 2021. PMID: 34475100 Free PMC article.

9

Expression Profiling of Notch Signalling Pathway and Gamma-Secretase Activity in the Brain of Ts1Cje Mouse Model of Down Syndrome.

Yusof HH, Lee HC, Seth EA, Wu X, Hewitt CA, Scott HS, Cheah PS, Li YM, Chau DM, Ling KH. Yusof HH, et al. Among authors: li ym. J Mol Neurosci. 2019 Apr;67(4):632-642. doi: 10.1007/s12031-019-01275-2. Epub 2019 Feb 13. J Mol Neurosci. 2019. PMID: 30758748 Free PMC article.

10

Processing of Notch and amyloid precursor protein by gamma-secretase is spatially distinct.

Tarassishin L, Yin YI, Bassit B, Li YM. Tarassishin L, et al. Among authors: li ym. Proc Natl Acad Sci U S A. 2004 Dec 7;101(49):17050-5. doi: 10.1073/pnas.0408007101. Epub 2004 Nov 24. Proc Natl Acad Sci U S A. 2004. PMID: 15563588 Free PMC article.

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