Name	Known for
Michelle Jenner Isabel de Castilla Isabel de Castilla See fewer	Isabel (2011)
Rodolfo Sancho Fernando de Aragón Fernando de Aragón See fewer	Isabel (2011)
Ramon Madaula Gonzalo Chacón (as Ramón Madaula) Gonzalo Chacón (as Ramón Madaula) See fewer	Isabel (2011)
Francesc Garrido Juan Rodríguez de Fonseca Juan Rodríguez de Fonseca See fewer	The Sea Inside (2004)
Jordi Díaz Andrés de Cabrera Andrés de Cabrera See fewer	Isabel (2011)
Jorge Bosch Alejandro VI Alejandro VI See fewer	Los lobos de Washington (1999)
José Pedro Carrión Luis de Tremoille Luis de Tremoille See fewer	Medea 2 (2006)
Abel Folk Francisco de Busleyden Francisco de Busleyden See fewer	La banyera (2021)
Irene Escolar Juana I de Castilla Juana I de Castilla See fewer	An Autumn Without Berlin (2015)
Raúl Mérida Felipe el Hermoso Felipe el Hermoso See fewer	Un golpe de suerte (2009)
Álvaro Monje Juan II de Portugal Juan II de Portugal See fewer	Sexy Beast (2000)
Ainhoa Santamaría Beatriz de Bobadilla Beatriz de Bobadilla See fewer	Parallel Mothers (2021)
Héctor Carballo Carlos VIII Carlos VIII See fewer	Isabel (2011)
Iván Hermés Manuel I de Portugal Manuel I de Portugal See fewer	Al salir de clase (1997)
María Cantuel Princesa Isabel Princesa Isabel See fewer	The Witches of Calenda (2012)
Marta Belmonte Ana de Bretaña Ana de Bretaña See fewer	Una Vida Menos En Canarias (2024)
Úrsula Corberó Margarita de Austria Margarita de Austria See fewer	Money Heist (2017)
Adrián Lamana Príncipe Juan (as Adrian Lamana) Príncipe Juan (as Adrian Lamana) See fewer	The Devil's Backbone (2001)
Nacho Aldeguer César Borgia César Borgia See fewer	The Mallorca Files (2019)
Jonás Berami Diego Colón (as Jonás Beramí) Diego Colón (as Jonás Beramí) See fewer	Foam Party! (2017)
Fernando Guillén Cuervo Gutierre Gómez de Fuensalida Gutierre Gómez de Fuensalida See fewer	Quantum of Solace (2008)
Eusebio Poncela Francisco Jiménez de Cisneros Francisco Jiménez de Cisneros See fewer	El accidente (2017)
Clara Sanchis Isabel de Portugal (as Clara Sanchis) Isabel de Portugal (as Clara Sanchis) See fewer	Isabel (2011)
Julio Manrique Cristóbal Colón Cristóbal Colón See fewer	Parallel Mothers (2021)
Nuria Gallardo Beatriz de Braganza y Portugal Beatriz de Braganza y Portugal See fewer	Voyage to Nowhere (1986)
Antonio Torres Actor Actor See fewer	Fuga de noche (2004)