Extended Data Fig. 2. Population dynamics in the laboratory population and computational simulation in four conditions.
(A-D) Data from worms in the laboratory population (black) and corresponding simulations (red) graphed as in the laboratory population; culling and feeding schedules show the parameter that was varied in blue. The laboratory population data in panel B (10% culling all stages and 10 mg feeding every 24 hours) was used as the training set to determine the value of the following parameters: 1) cost of living and 2) metabolic efficiency (see Supplementary Section 4). (E-G) Comparisons of population summary statistics from the laboratory population (black) and corresponding simulations (red): Average and maximum worm number in initialization and maintenance phase; average, maximum, and minimum worm number in the maintenance phase (see Figure 1B). Culling and feeding schedules show the parameter that was varied in blue. The red simulated data show similar patterns as the black laboratory data with changing culling and feeding conditions. Values are mean +/− standard deviation of three biological replicates conducted in parallel of wild-type worm populations in the laboratory and three computational simulations.