Figure 7: Effects of intrastriatal perfusion of a D1-like receptor inhibitor analyzed with respect to pre-drug basal levels.
A. Basal neurochemical levels expressed as a percent of average basal levels. B. Time courses of optically stimulated neurochemical levels before and during intrastriatal perfusion of SCH 23390 (100 μM). C. Optically evoked overflow expressed as area under the curve for data normalized to pre-drug basal levels (AUC (%)). Data are means ± SEMs. *P<0.05 vs. pre-drug. N=4 mice. %Basal data points in A represent the means of six measurements just prior to the first stimulation (errors not shown). The AUC datapoints in C are means for the three stimuli (errors not shown).