ZA903758B - Dehydrocholecalciferol derivatives - Google Patents
Dehydrocholecalciferol derivativesInfo
- Publication number
- ZA903758B ZA903758B ZA903758A ZA903758A ZA903758B ZA 903758 B ZA903758 B ZA 903758B ZA 903758 A ZA903758 A ZA 903758A ZA 903758 A ZA903758 A ZA 903758A ZA 903758 B ZA903758 B ZA 903758B
- Authority
- ZA
- South Africa
- Prior art keywords
- dehydrocholecalciferol
- derivatives
- deuterium
- new
- dehydrocholecalciferal
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/008—Preparations for oily skin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Birds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
Abstract
The use of dehydrocholecalciferal derivs. of formula (I) to make pharmaceuticals for treating diseases of the sebaceous glands is new. (Where R = H or OH; A = CC, (E)-CH=CH or CH2CH2; R'' = H or, where A = C=C, it can also be deuterium). (I) are new cpds. where R'' = deuterium.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US35371689A | 1989-05-18 | 1989-05-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA903758B true ZA903758B (en) | 1992-01-29 |
Family
ID=23390270
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA903758A ZA903758B (en) | 1989-05-18 | 1990-05-16 | Dehydrocholecalciferol derivatives |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP0398217B1 (en) |
JP (1) | JPH0686381B2 (en) |
AT (1) | ATE99942T1 (en) |
AU (1) | AU636609B2 (en) |
CA (1) | CA2016985C (en) |
DE (1) | DE69005897D1 (en) |
DK (1) | DK0398217T3 (en) |
IE (1) | IE64186B1 (en) |
NZ (1) | NZ233704A (en) |
ZA (1) | ZA903758B (en) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA8923B (en) * | 1988-01-20 | 1989-09-27 | Hoffmann La Roche | 16-dehydro-vitamin d3-derivatives |
GB9004544D0 (en) * | 1990-03-01 | 1990-04-25 | Leo Pharm Prod Ltd | Novel treatment ii |
GB9017890D0 (en) * | 1990-08-15 | 1990-09-26 | Leo Pharm Prod Ltd | Chemical compounds i |
IL103224A (en) * | 1992-09-18 | 1998-08-16 | Teva Pharma | Stabilized pharmaceutical compositions containing derivatives of vitamins d2 and d3 |
TW267161B (en) * | 1992-11-20 | 1996-01-01 | Hoffmann La Roche | |
US5428029A (en) * | 1993-11-24 | 1995-06-27 | Hoffmann-La Roche Inc. | Vitamin D3 fluorinated analogs |
AU708679B2 (en) * | 1996-03-21 | 1999-08-12 | F. Hoffmann-La Roche Ag | 1,25-dihydroxy-16,22,23-trisdehydro-cholecalciferol derivatives |
GB9625271D0 (en) * | 1996-12-04 | 1997-01-22 | Leo Pharm Prod Ltd | Chemical compounds |
ATE237586T1 (en) * | 1997-05-02 | 2003-05-15 | Duphar Int Res | METHOD FOR PRODUCING 16-DEHYDRO VITAMIN D COMPOUNDS |
US9221753B2 (en) * | 2004-02-03 | 2015-12-29 | Chugai Seiyaku Kabushiki Kaisha | Process for the synthesis of vitamin D compounds and intermediates for the synthesis of the compounds |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4610978A (en) * | 1983-03-22 | 1986-09-09 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Compositions containing 1α-hydroxycholecalciferol for topical treatment of skin disorders and methods employing same |
EP0215956A4 (en) * | 1985-03-14 | 1988-09-07 | Chugai Pharmaceutical Co Ltd | Composition for treating skin disease. |
US4898855A (en) * | 1987-09-14 | 1990-02-06 | Hoffman-La Roche Inc. | Deuterated analogs of 1,25-dihydroxycholecalciferol |
ZA8923B (en) * | 1988-01-20 | 1989-09-27 | Hoffmann La Roche | 16-dehydro-vitamin d3-derivatives |
US4804502A (en) * | 1988-01-20 | 1989-02-14 | Hoffmann-La Roche Inc. | Vitamin D compounds |
-
1990
- 1990-05-14 AT AT90109032T patent/ATE99942T1/en not_active IP Right Cessation
- 1990-05-14 DE DE90109032T patent/DE69005897D1/en not_active Expired - Fee Related
- 1990-05-14 DK DK90109032.4T patent/DK0398217T3/en active
- 1990-05-14 EP EP90109032A patent/EP0398217B1/en not_active Expired - Lifetime
- 1990-05-16 ZA ZA903758A patent/ZA903758B/en unknown
- 1990-05-16 NZ NZ233704A patent/NZ233704A/en unknown
- 1990-05-17 JP JP2128107A patent/JPH0686381B2/en not_active Expired - Fee Related
- 1990-05-17 AU AU55165/90A patent/AU636609B2/en not_active Ceased
- 1990-05-17 IE IE178090A patent/IE64186B1/en unknown
- 1990-05-17 CA CA002016985A patent/CA2016985C/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JPH0317019A (en) | 1991-01-25 |
EP0398217A1 (en) | 1990-11-22 |
EP0398217B1 (en) | 1994-01-12 |
DE69005897D1 (en) | 1994-02-24 |
JPH0686381B2 (en) | 1994-11-02 |
CA2016985C (en) | 2001-03-27 |
IE901780L (en) | 1990-11-18 |
NZ233704A (en) | 1992-11-25 |
ATE99942T1 (en) | 1994-01-15 |
IE64186B1 (en) | 1995-07-12 |
CA2016985A1 (en) | 1990-11-18 |
AU636609B2 (en) | 1993-05-06 |
DK0398217T3 (en) | 1994-02-14 |
AU5516590A (en) | 1990-11-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MY100343A (en) | Amide derivative and external medicament comprising same | |
NO860424L (en) | PROCEDURE FOR THE PREPARATION OF 6-THIOXANTHIN DERIVATIVES. | |
DE3572820D1 (en) | 1,4:3,6-dianhydro-hexite derivatives, process for their preparation and their use as medicaments | |
GB1459571A (en) | Thiophene-2-sulphonamide derivatives and their use as therapeutic agents sheet orienting apparatus | |
IE901780L (en) | Dehydrocholecalciferol derivatives | |
DE3662265D1 (en) | Irreversible dopamine-b-hydroxylase inhibitors | |
SE8500996D0 (en) | METHOD OF TREATMENT | |
ZA938478B (en) | Vitamin D3 analogs | |
NO902157L (en) | BUTIC ACID DERIVATIVES FOR THERAPEUTIC USE. | |
DE3463385D1 (en) | Compounds for treating hypertension | |
DK7286D0 (en) | OCTAHYDROINDOLIZINER | |
DE3277971D1 (en) | Acylamino-4-aza-1-adamantanes, process for their preparation and their therapeutic use | |
NZ219052A (en) | Octahydroindolizine derivatives and pharmaceutical compositions | |
GR3003769T3 (en) | ||
DE3469358D1 (en) | Novel 3-(4'-aminobutylamino)-propylamino-bleomycin derivatives, a process for their preparation and their use as medicaments | |
IT1182847B (en) | Agents for treating immuno-deficiency-related complaints | |
ES8703826A3 (en) | Hydroxy-methyl-propyl acetyl salicylate -prepn. | |
FR2408348A1 (en) | (2,4-Di:oxy-6-methyl-pyrimidinyl-5-sulphonamino) di:phenyl-sulphone - used to treat skin rash caused by rheumatoid arthritis |