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ZA838831B - New nitro aliphatic compounds,process for preparation thereof and use thereof - Google Patents

New nitro aliphatic compounds,process for preparation thereof and use thereof

Info

Publication number
ZA838831B
ZA838831B ZA838831A ZA838831A ZA838831B ZA 838831 B ZA838831 B ZA 838831B ZA 838831 A ZA838831 A ZA 838831A ZA 838831 A ZA838831 A ZA 838831A ZA 838831 B ZA838831 B ZA 838831B
Authority
ZA
South Africa
Prior art keywords
hydrogen
lower alkyl
preparation
aliphatic compounds
new nitro
Prior art date
Application number
ZA838831A
Other languages
English (en)
Inventor
Iwami Morita
Okamoto Masanori
Takase Shigehiro
Uchida Itsuo
Umehara Kazuyoshi
Kohsaka Masanobu
Imanaka Hiroshi
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of ZA838831B publication Critical patent/ZA838831B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36Oxygen or sulfur atoms
    • C07D207/402,5-Pyrrolidine-diones
    • C07D207/4042,5-Pyrrolidine-diones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. succinimide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/32Oximes
    • C07C251/34Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C251/36Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with the carbon atoms of the oxyimino groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C251/40Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with the carbon atoms of the oxyimino groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of an unsaturated carbon skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/44Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by —CHO groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/50Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C205/51Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being saturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00Ethers; Compounds having groups, groups or groups
    • C07C43/02Ethers
    • C07C43/20Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/41Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by hydrogenolysis or reduction of carboxylic groups or functional derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/03Monocarboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182Radicals derived from carboxylic acids
    • C07D295/185Radicals derived from carboxylic acids from aliphatic carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrrole Compounds (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
ZA838831A 1982-12-31 1983-11-25 New nitro aliphatic compounds,process for preparation thereof and use thereof ZA838831B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8237068 1982-12-31

Publications (1)

Publication Number Publication Date
ZA838831B true ZA838831B (en) 1984-07-25

Family

ID=10535311

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA838831A ZA838831B (en) 1982-12-31 1983-11-25 New nitro aliphatic compounds,process for preparation thereof and use thereof

Country Status (18)

Country Link
US (4) US4767768A (es)
EP (1) EP0113106B1 (es)
JP (2) JPS59152366A (es)
KR (1) KR910006761B1 (es)
AT (1) ATE19773T1 (es)
AU (1) AU560980B2 (es)
CA (1) CA1231949A (es)
DE (1) DE3363550D1 (es)
DK (1) DK607783A (es)
ES (1) ES528561A0 (es)
FI (1) FI78904C (es)
GR (1) GR79553B (es)
HU (1) HU200747B (es)
IE (1) IE56312B1 (es)
NO (1) NO158379C (es)
PH (1) PH19042A (es)
SU (1) SU1389678A3 (es)
ZA (1) ZA838831B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3601927A1 (de) * 1986-01-23 1987-07-30 Basf Ag Alpha, beta-substituierte acroleine, verfahren zu deren herstellung und deren verwendung
DE3923896A1 (de) * 1989-07-19 1991-01-31 Basf Ag 1-aza-butadiene und diese verbindungen enthaltende fungizide
CA2038716A1 (en) * 1990-03-28 1991-09-29 Yoshio Ueda Stabilizer for 4-ethyl-2-hydroxyimino-5-nitro-3-hexenamide-containing preparation, stabilizing method thereof and drug stabilized thereby
US5254733A (en) * 1990-10-31 1993-10-19 Fujisawa Pharmaceutical Co., Ltd. Process for producing an aliphatic amide and salts thereof
ES2102512T3 (es) * 1991-08-13 1997-08-01 Fujisawa Pharmaceutical Co Inhibidor de la hipertrofia de vasos sanguineos.
JP3456211B2 (ja) * 1991-09-27 2003-10-14 藤沢薬品工業株式会社 持続性製剤
US5495023A (en) * 1991-11-15 1996-02-27 Fujisawa Pharmaceutical Co., Ltd. Nitro compounds, process for preparation thereof and use thereof
WO1996005819A1 (fr) * 1994-08-19 1996-02-29 Fujisawa Pharmaceutical Co., Ltd. Remede contre l'hypertension portale
FR2735470B1 (fr) * 1995-06-13 1997-07-11 Synthelabo Nitrocetones et nitroximes, leur preparation et leur application en therapeutique
DE60116874T2 (de) * 2000-07-03 2006-11-02 Speedel Pharma Ag Verfahren zur herstellung von (r)-2-alkyl-3-phenyl-1-propanolen
GB0419693D0 (en) * 2004-09-06 2004-10-06 Givaudan Sa Anti-bacterial compounds
CN101180288A (zh) 2005-03-31 2008-05-14 科学与工业研究会 与抗感染药物联用的芳香族取代的戊二烯酸酰胺
MX2012004845A (es) 2009-11-02 2012-05-29 Firmenich & Cie Odorizantes con notas anisicas.
CN103242187B (zh) * 2013-04-28 2016-01-06 华南理工大学 抗菌防腐剂山梨酸氨基酸酯衍生物及其制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3849476A (en) * 1968-05-25 1974-11-19 Mitsubishi Chem Ind Process for manufacturing 6-nitro-2-substituted hexanoic acid esters
NL6907904A (es) * 1968-05-30 1969-12-02
US3849481A (en) * 1970-12-11 1974-11-19 Allied Chem Hydrogenation of lysine precursors
US3803231A (en) * 1970-12-11 1974-04-09 Allied Chem Ammonolysis of 2-nitro-6-oximino cyclohexanone
US3869481A (en) * 1971-09-16 1975-03-04 Searle & Co 17alpha-alkanoyloxy-6alpha-methyl-3beta-trialkyl-siloxypregn-4-en-20-ones
US3732303A (en) * 1971-10-14 1973-05-08 Allied Chem Process for the preparation of 2-oximino-6-nitro hexanamide
US3746763A (en) * 1971-12-29 1973-07-17 Allied Chem Two-step hydrogenation of lysine amide precursors
US3873301A (en) * 1973-08-09 1975-03-25 Allied Chem Nitro-oximino alkanoic acids as plant growth regulants
US4128581A (en) * 1975-02-27 1978-12-05 Diamond Shamrock Corporation Ketoxime carbamates
US4219660A (en) * 1977-06-24 1980-08-26 Hoffmann-La Roche Inc. Conjugated diene derivatives

Also Published As

Publication number Publication date
JPH0219822B2 (es) 1990-05-07
NO158379B (no) 1988-05-24
DK607783D0 (da) 1983-12-30
FI78904C (fi) 1989-10-10
JPH02160750A (ja) 1990-06-20
HU200747B (en) 1990-08-28
FI78904B (fi) 1989-06-30
FI834702A0 (fi) 1983-12-21
KR840007579A (ko) 1984-12-08
FI834702A (fi) 1984-07-01
IE56312B1 (en) 1991-06-19
EP0113106A1 (en) 1984-07-11
US4767768A (en) 1988-08-30
SU1389678A3 (ru) 1988-04-15
NO834884L (no) 1984-07-02
ES8504682A1 (es) 1985-05-01
PH19042A (en) 1985-12-11
AU2174483A (en) 1984-07-05
NO158379C (no) 1988-08-31
CA1231949A (en) 1988-01-26
US4782088A (en) 1988-11-01
JPH0417944B2 (es) 1992-03-26
US4778804A (en) 1988-10-18
KR910006761B1 (ko) 1991-09-02
ES528561A0 (es) 1985-05-01
IE832788L (en) 1984-06-30
DK607783A (da) 1984-07-01
EP0113106B1 (en) 1986-05-14
JPS59152366A (ja) 1984-08-31
ATE19773T1 (de) 1986-05-15
AU560980B2 (en) 1987-04-30
US4863926A (en) 1989-09-05
DE3363550D1 (en) 1986-06-19
GR79553B (es) 1984-10-30

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