UY27662A1 - Inhibidores de la mocroglia para interrumpir reacciones inmunes asociadas con interleucina 12 y ifny. - Google Patents

Inhibidores de la mocroglia para interrumpir reacciones inmunes asociadas con interleucina 12 y ifny.

Info

Publication number: UY27662A1
Authority: UY; Uruguay
Prior art keywords: inhibitors; mocrogly; interleucine; ifny; interrupt
Prior art date: 2002-02-15

Application number

UY27662A

Other languages

English (en)

Spanish (es)

Inventor

Thorsten Blume

Wolfgang Halfbrodt

Joachin Kuhnke

Ursula Monning

Bernd Elger

Herbert Schneider

Wolf-Dietrich Docke

Original Assignee

Schering Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-02-15

Filing date

2003-02-11

Publication date

2003-09-30

2003-02-11 Application filed by Schering Ag filed Critical Schering Ag

2003-09-30 Publication of UY27662A1 publication Critical patent/UY27662A1/es

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Diabetes (AREA)
Pulmonology (AREA)
Dermatology (AREA)
Hematology (AREA)
Epidemiology (AREA)
Rheumatology (AREA)
Transplantation (AREA)
Obesity (AREA)
Endocrinology (AREA)
Virology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Pain & Pain Management (AREA)
Gastroenterology & Hepatology (AREA)
Emergency Medicine (AREA)
Physical Education & Sports Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Plural Heterocyclic Compounds (AREA)

UY27662A 2002-02-15 2003-02-11 Inhibidores de la mocroglia para interrumpir reacciones inmunes asociadas con interleucina 12 y ifny. UY27662A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE10207843A DE10207843A1 (de)	2002-02-15	2002-02-15	Mikrolia-Inhibitoren zur Unterbrechung von Interleukin 12 und IFN-gamma vermittelten Immunreaktionen

Publications (1)

Publication Number	Publication Date
UY27662A1 true UY27662A1 (es)	2003-09-30

Family

ID=27674912

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
UY27662A UY27662A1 (es)	2002-02-15	2003-02-11	Inhibidores de la mocroglia para interrumpir reacciones inmunes asociadas con interleucina 12 y ifny.

Country Status (21)

Country	Link
EP (1)	EP1474138A1 (de)
JP (1)	JP2005522447A (de)
KR (1)	KR20040084909A (de)
CN (1)	CN1756546A (de)
AR (1)	AR039556A1 (de)
AU (1)	AU2003245523A1 (de)
BR (1)	BR0307706A (de)
CA (1)	CA2475770A1 (de)
DE (1)	DE10207843A1 (de)
EC (1)	ECSP045297A (de)
MX (1)	MXPA04007943A (de)
NO (1)	NO20043840L (de)
PE (1)	PE20030906A1 (de)
PL (1)	PL371327A1 (de)
RS (1)	RS71304A (de)
RU (1)	RU2004127677A (de)
TW (1)	TW200306823A (de)
UA (1)	UA81111C2 (de)
UY (1)	UY27662A1 (de)
WO (1)	WO2003068225A1 (de)
ZA (1)	ZA200407382B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE10207844A1 (de) *	2002-02-15	2003-09-04	Schering Ag	1-Phenyl-2-heteroaryl-substituierte Benzimidazolderivate, deren Verwendung zur Herstellung von Arzneimitteln sowie diese Derivate enthaltende pharmazeutische Präparate
CA2601557A1 (en) *	2005-03-17	2006-09-21	Proyteco De Biomedicina Cima, S.L.	Use of 5'-methylthioadenosine (mta) in the prevention and/or treatment of autoimmune diseases and/or transplant rejection
EP2858983B1 (de) *	2012-06-11	2018-04-18	UCB Biopharma SPRL	Tnf-alpha-modulierende benzimidazole
US9586949B2 (en)	2015-02-09	2017-03-07	Incyte Corporation	Aza-heteroaryl compounds as PI3K-gamma inhibitors
WO2017079519A1 (en)	2015-11-06	2017-05-11	Incyte Corporation	Heterocyclic compounds as pi3k-gamma inhibitors
EP3741747B1 (de) *	2015-12-15	2024-10-16	The Board of Trustees of the Leland Stanford Junior University	Verfahren zur prävention und/oder behandlung von angststörungen
US20170190689A1 (en)	2016-01-05	2017-07-06	Incyte Corporation	Pyridine and pyridimine compounds as pi3k-gamma inhibitors
TW201803871A (zh)	2016-06-24	2018-02-01	英塞特公司	作為ＰＩ３Ｋ-γ抑制劑之雜環化合物
CN118063470A (zh)	2017-10-18	2024-05-24	因赛特公司	作为PI3K-γ抑制剂的由叔羟基取代的缩合咪唑衍生物
HRP20240252T1 (hr)	2018-09-05	2024-05-24	Incyte Corporation	Kristalni oblici inhibitora fosfoinozitid 3 kinaze (pi3k)
PL3860998T3 (pl)	2018-10-05	2024-06-17	Annapurna Bio Inc.	Związki i kompozycje do leczenia schorzeń związanych z aktywnością receptora apj
CN112341450B (zh) *	2019-08-09	2022-05-17	成都先导药物开发股份有限公司	一种免疫调节剂
CN112341451B (zh) *	2019-08-09	2022-06-17	成都先导药物开发股份有限公司	一种免疫调节剂

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4330959A1 (de) *	1993-09-09	1995-03-16	Schering Ag	Neue Benzimidazolderivate, Verfahren zu ihrer Herstellung und ihre pharmazeutische Verwendung
BR0107628A (pt) *	2000-01-14	2002-10-08	Schering Ag	l,2-diarilbenzimidazóis para tratamento de doenças que estão associadas a uma ativação microglial
DE10134775A1 (de) *	2001-07-06	2003-01-30	Schering Ag	1-Alkyl-2.aryl-benzimidazolderivate, deren Verwendung zur Herstellung von Arzneimitteln sowie diese Derivate enthaltende pharmazeutische Präparate
DE10135050A1 (de) *	2001-07-09	2003-02-06	Schering Ag	1-Ary1-2-N-, S- oder O-substituierte Benzimidazolderivate, deren Verwendung zur Herstellung von Arzneimitteln sowie diese Derivate enthaltende pharmazeutische Präparate

2002
- 2002-02-15 DE DE10207843A patent/DE10207843A1/de not_active Ceased
2003
- 2003-01-17 PL PL03371327A patent/PL371327A1/xx not_active Application Discontinuation
- 2003-01-17 WO PCT/EP2003/000467 patent/WO2003068225A1/de active Application Filing
- 2003-01-17 BR BR0307706-3A patent/BR0307706A/pt not_active IP Right Cessation
- 2003-01-17 RS YU71304A patent/RS71304A/sr unknown
- 2003-01-17 AU AU2003245523A patent/AU2003245523A1/en not_active Abandoned
- 2003-01-17 CN CNA038039923A patent/CN1756546A/zh active Pending
- 2003-01-17 RU RU2004127677/15A patent/RU2004127677A/ru unknown
- 2003-01-17 UA UA20040907401A patent/UA81111C2/uk unknown
- 2003-01-17 CA CA002475770A patent/CA2475770A1/en not_active Abandoned
- 2003-01-17 EP EP03739380A patent/EP1474138A1/de not_active Withdrawn
- 2003-01-17 MX MXPA04007943A patent/MXPA04007943A/es unknown
- 2003-01-17 KR KR10-2004-7012557A patent/KR20040084909A/ko not_active Application Discontinuation
- 2003-01-17 JP JP2003567407A patent/JP2005522447A/ja active Pending
- 2003-02-03 PE PE2003000119A patent/PE20030906A1/es not_active Application Discontinuation
- 2003-02-11 UY UY27662A patent/UY27662A1/es not_active Application Discontinuation
- 2003-02-12 AR ARP030100436A patent/AR039556A1/es unknown
- 2003-02-14 TW TW092103072A patent/TW200306823A/zh unknown
2004
- 2004-09-14 ZA ZA200407382A patent/ZA200407382B/en unknown
- 2004-09-14 EC EC2004005297A patent/ECSP045297A/es unknown
- 2004-09-14 NO NO20043840A patent/NO20043840L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
RS71304A (en)	2006-10-27
EP1474138A1 (de)	2004-11-10
RU2004127677A (ru)	2005-06-10
ZA200407382B (en)	2005-09-14
AR039556A1 (es)	2005-02-23
KR20040084909A (ko)	2004-10-06
ECSP045297A (es)	2004-10-26
WO2003068225A1 (de)	2003-08-21
MXPA04007943A (es)	2004-11-26
CA2475770A1 (en)	2003-08-21
TW200306823A (en)	2003-12-01
PL371327A1 (en)	2005-06-13
JP2005522447A (ja)	2005-07-28
UA81111C2 (en)	2007-12-10
NO20043840L (no)	2004-11-12
PE20030906A1 (es)	2004-01-17
DE10207843A1 (de)	2003-09-04
AU2003245523A1 (en)	2003-09-04
CN1756546A (zh)	2006-04-05
BR0307706A (pt)	2005-01-11

Publication	Publication Date	Title
UY27662A1 (es)	2003-09-30	Inhibidores de la mocroglia para interrumpir reacciones inmunes asociadas con interleucina 12 y ifny.
CR7875A (es)	2008-11-07	Variantes de inmunoglobina y usos de esto
ES2148525T3 (es)	2000-10-16	Inmunomoduladores.
FI950255A0 (fi)	1995-01-20	Venyvä absorboiva rakenne
AR095541A1 (es)	2015-10-21	Muteínas de interleucina-2 (il-2) para la expansión de células t reguladoras
CR7786A (es)	2005-10-21	Anticuerpos neutralizantes contra gdf-8 y el uso de los mismos
UY27720A1 (es)	2003-10-31	Aroilpiridinonas monocíclicas,
AR027221A1 (es)	2003-03-19	Antagonistas del factor liberador de corticotropina
BRPI0417072B8 (pt)	2021-05-25	"uso de antagonista de interleucina-6 (il-6)".
CL2008002852A1 (es)	2009-03-27	Compuestos derivados de 7-fluoro-5-metil-2-(fenilamino)-6,7,8,9-tetrahidro-5h-pirimido[4,5-b][1,4]diazepin-6(7h)-ona; composicion farmaceutica que comprende a dichos compuestos; y su uso en el tratamiento de canceer, inflamacion, alopecia, enfermedades autoinmune, cardiovasculares, infecciosas, nefrologicas, neurodfegenerativas, cutaneas y oseas.
TR200001228T2 (tr)	2001-01-22	T yardımcı hücre tür 2 kökenli bağışıklık hastalıklarının retinoit antagonistlerle tedavisi
AR040130A1 (es)	2005-03-16	Esteres de etonogestrel, su uso como anticopceptivo y para el tratamiento de desordenes ginecologicos
UY27725A1 (es)	2003-10-31	Material micronizado cristalino, procedimiento para su preparación y su utilización para la preparación de un medicamento.
UY26370A1 (es)	2000-12-29	"imidazo-5-il-aminas bicíclicas, medicamentos que las contienen, su uso para la preparación de medicamentos y procedimiento para su preparación".
CL2003002678A1 (es)	2005-04-22	Compuestos derivados de piperidina, moduladores de la actividad del receptor ccr5; procedimiento de preparacion; composicion farmaceutica, y su uso en el tratamiento de enfermedades inmunologicas, inflamatorias, asma, artritis reumatoidea y ateroescl
UY28080A1 (es)	2004-05-31	Isómeros posicionales del ifn peg alfa 2a
SI1492773T1 (sl)	2009-06-30	4-(heterociklil)-benzensulfoksiminske spojine za zdravljenje vnetja
ATE423848T1 (de)	2009-03-15	Auslösender rezeptor der an der natürlichen cytotoxizität der menschlichen natürlichen killerzellen (natural killer cells) beteiligt ist und antikörper die diesen rezeptor identifizieren
CR7441A (es)	2006-02-06	Inhibidores de la microglia para interrumpir reacciones inmunes asociadas con interleucina 12 y ifny
IT1299264B1 (it)	2000-02-29	Composizioni farmaceutiche topiche utili per il trattamento di patologie cutanee su base infiammatoria, immunitaria o proliferativa
UY27312A1 (es)	2003-02-28	Nuevos heterociclos 3
AR027694A1 (es)	2003-04-09	Uso de la proteina mia para el tratamiento de enfermedades autoinmunes
PT837672E (pt)	2004-03-31	Preparacoes e metodos para o tratamento de doencas mediadas por celulas t
PT1017667E (pt)	2004-04-30	2-amino-6-metil-7-acetil-tetralina e composicoes farmaceuticas para a prevencao e para o tratamento terapeutico de patologias inflamatorias e/ou de natureza autoimunitaria
ES2145114T3 (es)	2000-07-01	Combinacion de atovacuona con proguanil para el tratamiento de infecciones protozoarias.

Legal Events

Date	Code	Title	Description
2015-04-28	109	Application deemed to be withdrawn	Effective date: 20150428