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TR199701469T1 - �i�man (OB) proteinin etkilerini de�i�tiren bile�imlerin meydana ��kar�lmas� i�in y�ntem. - Google Patents

�i�man (OB) proteinin etkilerini de�i�tiren bile�imlerin meydana ��kar�lmas� i�in y�ntem.

Info

Publication number
TR199701469T1
TR199701469T1 TR97/01469T TR9701469T TR199701469T1 TR 199701469 T1 TR199701469 T1 TR 199701469T1 TR 97/01469 T TR97/01469 T TR 97/01469T TR 9701469 T TR9701469 T TR 9701469T TR 199701469 T1 TR199701469 T1 TR 199701469T1
Authority
TR
Turkey
Prior art keywords
protein
informant
effect
composition
response element
Prior art date
Application number
TR97/01469T
Other languages
English (en)
Turkish (tr)
Inventor
James Beeley Lee
Anthony Godwin Smith Richard
Original Assignee
Smithkline Beecham P.L.C
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9510857.7A external-priority patent/GB9510857D0/en
Priority claimed from GBGB9511602.6A external-priority patent/GB9511602D0/en
Application filed by Smithkline Beecham P.L.C filed Critical Smithkline Beecham P.L.C
Publication of TR199701469T1 publication Critical patent/TR199701469T1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/5759—Products of obesity genes, e.g. leptin, obese (OB), tub, fat

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
TR97/01469T 1995-05-30 1996-05-28 �i�man (OB) proteinin etkilerini de�i�tiren bile�imlerin meydana ��kar�lmas� i�in y�ntem. TR199701469T1 (xx)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9510857.7A GB9510857D0 (en) 1995-05-30 1995-05-30 Novel assay
GBGB9511602.6A GB9511602D0 (en) 1995-06-08 1995-06-08 Novel assay

Publications (1)

Publication Number Publication Date
TR199701469T1 true TR199701469T1 (xx) 1998-03-21

Family

ID=26307107

Family Applications (1)

Application Number Title Priority Date Filing Date
TR97/01469T TR199701469T1 (xx) 1995-05-30 1996-05-28 �i�man (OB) proteinin etkilerini de�i�tiren bile�imlerin meydana ��kar�lmas� i�in y�ntem.

Country Status (15)

Country Link
EP (1) EP0832284A1 (pt)
JP (1) JPH11505725A (pt)
KR (1) KR19990022134A (pt)
CN (1) CN1192248A (pt)
AU (1) AU715215B2 (pt)
BR (1) BR9608686A (pt)
CA (1) CA2222409A1 (pt)
CZ (1) CZ379097A3 (pt)
HU (1) HUP9801744A3 (pt)
MX (1) MX9709360A (pt)
NO (1) NO975504L (pt)
NZ (1) NZ309777A (pt)
PL (1) PL323638A1 (pt)
TR (1) TR199701469T1 (pt)
WO (1) WO1996038586A1 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001968A (en) 1994-08-17 1999-12-14 The Rockefeller University OB polypeptides, modified forms and compositions
US6429290B1 (en) 1994-08-17 2002-08-06 The Rockefeller University OB polypeptides, modified forms and derivatives
US6007998A (en) * 1996-04-22 1999-12-28 Merck & Co., Inc. Leptin assay
WO1997040380A1 (en) * 1996-04-22 1997-10-30 Merck & Co., Inc. Leptin assay
US6001816A (en) * 1996-06-20 1999-12-14 Merck & Co., Inc. Gene therapy for leptin deficiency
PL333187A1 (en) * 1996-11-01 1999-11-22 Smithkline Beecham Plc Method of detecting compounds which modulate the performance of protein of obesity (ob)
IT1293533B1 (it) * 1997-07-14 1999-03-01 Angeletti P Ist Richerche Bio Metodo per la selezione di molecole in grado di mimare, inibire o potenziare gli effetti della interazione tra leptina e cellule che
WO1999023493A1 (en) * 1997-10-31 1999-05-14 The Rockefeller University Methods of identifying agents that modulate leptin activity
WO1999040946A2 (en) * 1998-02-11 1999-08-19 Beth Israel Deaconess Medical Center Methods and compositions for modulating leptin activity
GB9814199D0 (en) * 1998-06-30 1998-08-26 Univ Buckingham Novel method
GB9828087D0 (en) * 1998-12-18 1999-02-17 Smithkline Beecham Plc Novel method

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995008001A1 (en) * 1993-09-15 1995-03-23 New York University Dna sequence which binds transcriptional regulatory proteins activated in response to various cytokines and uses thereof
EP0722497A1 (en) * 1994-04-14 1996-07-24 Ligand Pharmaceuticals, Inc. Dna spacer regulatory elements responsive to cytokines and methods for their use

Also Published As

Publication number Publication date
CA2222409A1 (en) 1996-12-05
HUP9801744A2 (hu) 1998-10-28
AU715215B2 (en) 2000-01-20
HUP9801744A3 (en) 2000-06-28
AU6002396A (en) 1996-12-18
NO975504D0 (no) 1997-11-28
WO1996038586A1 (en) 1996-12-05
NZ309777A (en) 2000-01-28
EP0832284A1 (en) 1998-04-01
MX9709360A (es) 1998-02-28
JPH11505725A (ja) 1999-05-25
BR9608686A (pt) 1999-07-06
PL323638A1 (en) 1998-04-14
CN1192248A (zh) 1998-09-02
NO975504L (no) 1997-11-28
CZ379097A3 (cs) 1998-05-13
KR19990022134A (ko) 1999-03-25

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