SG11201609739UA - Derivatives of dolaproine-dolaisoleuine peptides - Google Patents
Derivatives of dolaproine-dolaisoleuine peptidesInfo
- Publication number
- SG11201609739UA SG11201609739UA SG11201609739UA SG11201609739UA SG11201609739UA SG 11201609739U A SG11201609739U A SG 11201609739UA SG 11201609739U A SG11201609739U A SG 11201609739UA SG 11201609739U A SG11201609739U A SG 11201609739UA SG 11201609739U A SG11201609739U A SG 11201609739UA
- Authority
- SG
- Singapore
- Prior art keywords
- dolaisoleuine
- dolaproine
- peptides
- derivatives
- dolaisoleuine peptides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/03—Peptides having up to 20 amino acids in an undefined or only partially defined sequence; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/07—Tetrapeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/02—Linear peptides containing at least one abnormal peptide link
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462004084P | 2014-05-28 | 2014-05-28 | |
| PCT/US2015/032704 WO2015183978A1 (en) | 2014-05-28 | 2015-05-27 | Derivatives of dolaproine-dolaisoleuine peptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201609739UA true SG11201609739UA (en) | 2016-12-29 |
Family
ID=54699722
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201609739UA SG11201609739UA (en) | 2014-05-28 | 2015-05-27 | Derivatives of dolaproine-dolaisoleuine peptides |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US20170190735A1 (de) |
| EP (1) | EP3149024B9 (de) |
| JP (3) | JP2017519740A (de) |
| KR (1) | KR102413079B1 (de) |
| CN (1) | CN107041139A (de) |
| ES (1) | ES2883023T3 (de) |
| RU (1) | RU2747989C2 (de) |
| SG (1) | SG11201609739UA (de) |
| WO (1) | WO2015183978A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11201609739UA (en) * | 2014-05-28 | 2016-12-29 | Agensys Inc | Derivatives of dolaproine-dolaisoleuine peptides |
| US10722593B2 (en) * | 2015-10-02 | 2020-07-28 | Sirenas Llc | Anti-cancer compounds and conjugates thereof |
| EP4321522A1 (de) * | 2022-08-12 | 2024-02-14 | Seagen Inc. | Zytotoxische verbindungen und konjugate davon |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2172069T3 (es) * | 1991-08-09 | 2002-09-16 | Teikoku Hormone Mfg Co Ltd | Derivado tetrapeptidico. |
| US5635483A (en) | 1992-12-03 | 1997-06-03 | Arizona Board Of Regents Acting On Behalf Of Arizona State University | Tumor inhibiting tetrapeptide bearing modified phenethyl amides |
| US6569834B1 (en) | 1992-12-03 | 2003-05-27 | George R. Pettit | Elucidation and synthesis of antineoplastic tetrapeptide w-aminoalkyl-amides |
| US5780588A (en) | 1993-01-26 | 1998-07-14 | Arizona Board Of Regents | Elucidation and synthesis of selected pentapeptides |
| JPH06234790A (ja) * | 1993-02-09 | 1994-08-23 | Teikoku Hormone Mfg Co Ltd | 新規テトラペプチドアミド誘導体 |
| WO1995009864A1 (fr) * | 1993-10-01 | 1995-04-13 | Teikoku Hormone Mfg. Co., Ltd. | Nouveau derive peptidique |
| US5530097A (en) * | 1994-08-01 | 1996-06-25 | Arizona Board Of Regents Acting On Behalf Of Arizona State University | Human cancer inhibitory peptide amides |
| US5521284A (en) * | 1994-08-01 | 1996-05-28 | Arizona Board Of Regents Acting On Behalf Of Arizona State University | Human cancer inhibitory pentapeptide amides and esters |
| US5663149A (en) | 1994-12-13 | 1997-09-02 | Arizona Board Of Regents Acting On Behalf Of Arizona State University | Human cancer inhibitory pentapeptide heterocyclic and halophenyl amides |
| US6323315B1 (en) * | 1999-09-10 | 2001-11-27 | Basf Aktiengesellschaft | Dolastatin peptides |
| US6884869B2 (en) * | 2001-04-30 | 2005-04-26 | Seattle Genetics, Inc. | Pentapeptide compounds and uses related thereto |
| DE602004025834D1 (de) | 2003-10-22 | 2010-04-15 | Univ Johns Hopkins | Die behandlung von tumoren |
| CA2572318A1 (en) * | 2004-07-02 | 2006-01-12 | Neutec Pharma Plc | Treatment of cancer |
| JP2008519863A (ja) * | 2004-11-12 | 2008-06-12 | シアトル ジェネティクス インコーポレイティッド | Ｎ末端にアミノ安息香酸単位を有するオーリスタチン |
| US7608592B2 (en) | 2005-06-30 | 2009-10-27 | Virobay, Inc. | HCV inhibitors |
| CN101242816B (zh) * | 2005-06-30 | 2012-10-31 | 维罗贝股份有限公司 | Hcv抑制剂 |
| ES2708763T3 (es) | 2005-07-07 | 2019-04-11 | Seattle Genetics Inc | Compuestos de monometilvalina que tienen modificaciones de la cadena lateral de fenilalanina en el extremo C |
| CN101932598B (zh) | 2008-01-30 | 2016-12-21 | 皮里斯股份公司 | 具有对人c-met受体酪氨酸激酶的亲和性的泪脂质运载蛋白的突变蛋白及其获得方法 |
| DK2265283T3 (da) * | 2008-03-18 | 2014-10-20 | Seattle Genetics Inc | Auristatin-lægemiddel-linker-konjugater |
| WO2009126934A2 (en) * | 2008-04-11 | 2009-10-15 | Seattle Genetics, Inc. | Detection and tratment of pancreatic, ovarian and other cancers |
| WO2012143495A2 (de) | 2011-04-21 | 2012-10-26 | Bayer Intellectual Property Gmbh | Neue binder-wirkstoff konjugate (adcs) und ihre verwendung |
| EP2699713B1 (de) * | 2011-07-08 | 2015-08-26 | Siemens Aktiengesellschaft | Schichtsystem mit zweilagiger metallischer schicht |
| US20130190248A1 (en) * | 2011-07-26 | 2013-07-25 | Agensys, Inc. | Substituted peptide analogs |
| PT2780039T (pt) * | 2011-11-17 | 2018-01-29 | Pfizer | Péptidos citotóxicos e seus conjugados de anticorpos e fármacos |
| CN107982545B (zh) * | 2012-05-15 | 2021-04-09 | 联宁（苏州）生物制药有限公司 | 药物偶联物，偶联方法，及其用途 |
| KR20150082548A (ko) * | 2012-11-07 | 2015-07-15 | 화이자 인코포레이티드 | 항-notch3 항체 및 항체-약물 접합체 |
| KR101763499B1 (ko) | 2012-11-07 | 2017-07-31 | 화이자 인코포레이티드 | 항-il-13 수용체 알파 2 항체 및 항체-약물 접합체 |
| SG11201609739UA (en) | 2014-05-28 | 2016-12-29 | Agensys Inc | Derivatives of dolaproine-dolaisoleuine peptides |
-
2015
- 2015-05-27 SG SG11201609739UA patent/SG11201609739UA/en unknown
- 2015-05-27 US US15/313,906 patent/US20170190735A1/en not_active Abandoned
- 2015-05-27 ES ES15799069T patent/ES2883023T3/es active Active
- 2015-05-27 CN CN201580041582.0A patent/CN107041139A/zh active Pending
- 2015-05-27 WO PCT/US2015/032704 patent/WO2015183978A1/en active Application Filing
- 2015-05-27 RU RU2016150426A patent/RU2747989C2/ru not_active Application Discontinuation
- 2015-05-27 KR KR1020167036764A patent/KR102413079B1/ko active IP Right Grant
- 2015-05-27 JP JP2016569825A patent/JP2017519740A/ja active Pending
- 2015-05-27 EP EP15799069.8A patent/EP3149024B9/de active Active
-
2019
- 2019-11-14 US US16/684,208 patent/US11312748B2/en active Active
-
2020
- 2020-05-07 JP JP2020081698A patent/JP6995160B2/ja active Active
-
2021
- 2021-12-14 JP JP2021202579A patent/JP7292366B2/ja active Active
-
2022
- 2022-03-18 US US17/698,353 patent/US20220204557A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20220204557A1 (en) | 2022-06-30 |
| EP3149024B9 (de) | 2021-10-27 |
| RU2747989C2 (ru) | 2021-05-18 |
| EP3149024B1 (de) | 2021-05-12 |
| RU2016150426A (ru) | 2018-07-03 |
| EP3149024A4 (de) | 2018-06-06 |
| RU2016150426A3 (de) | 2018-12-20 |
| KR102413079B1 (ko) | 2022-06-24 |
| WO2015183978A1 (en) | 2015-12-03 |
| US11312748B2 (en) | 2022-04-26 |
| CN107041139A (zh) | 2017-08-11 |
| JP6995160B2 (ja) | 2022-01-14 |
| US20200325170A1 (en) | 2020-10-15 |
| JP2022027896A (ja) | 2022-02-14 |
| JP7292366B2 (ja) | 2023-06-16 |
| US20170190735A1 (en) | 2017-07-06 |
| JP2020128405A (ja) | 2020-08-27 |
| JP2017519740A (ja) | 2017-07-20 |
| ES2883023T3 (es) | 2021-12-03 |
| KR20170005495A (ko) | 2017-01-13 |
| EP3149024A1 (de) | 2017-04-05 |
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