SE435281B - Forfarande for framstellning av prostaglandinderivat - Google Patents

Forfarande for framstellning av prostaglandinderivat

Info

Publication number: SE435281B
Authority: SE; Sweden
Prior art keywords: prostagland; ingredients; procedure; preparation; prostagland ingredients
Prior art date: 1976-02-04

Application number

SE7701045A

Other languages

English (en)

Other versions

SE7701045L (sv

Inventor

U F Axen

F H Lincoln

R A Johnson

R C Kelly

J E Pike

Original Assignee

Upjohn Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-02-04

Filing date

1977-02-01

Publication date

1984-09-17

1977-02-01 Application filed by Upjohn Co filed Critical Upjohn Co

1977-08-05 Publication of SE7701045L publication Critical patent/SE7701045L/sv

1984-09-17 Publication of SE435281B publication Critical patent/SE435281B/sv

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
- C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Furan Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Epoxy Compounds (AREA)

SE7701045A 1976-02-04 1977-02-01 Forfarande for framstellning av prostaglandinderivat SE435281B (sv)

Applications Claiming Priority (7)

Application Number	Priority Date	Filing Date
US65511076A	1976-02-04	1976-02-04
US71677176A	1976-08-23	1976-08-23
US71677076A	1976-08-23	1976-08-23
US71696076A	1976-08-23	1976-08-23
US71696976A	1976-08-23	1976-08-23
US71697276A	1976-08-23	1976-08-23
US72554876A	1976-09-22	1976-09-22

Publications (2)

Publication Number	Publication Date
SE7701045L SE7701045L (sv)	1977-08-05
SE435281B true SE435281B (sv)	1984-09-17

Family

ID=27569874

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE7701045A SE435281B (sv)	1976-02-04	1977-02-01	Forfarande for framstellning av prostaglandinderivat

Country Status (13)

Country	Link
JP (1)	JPS5936911B2 (sv)
BE (1)	BE851122A (sv)
CA (3)	CA1160627A (sv)
CH (2)	CH632245A5 (sv)
DE (1)	DE2702553C2 (sv)
FR (3)	FR2359125B1 (sv)
GB (1)	GB1554044A (sv)
HK (1)	HK9385A (sv)
IL (1)	IL51189A (sv)
MX (1)	MX4811E (sv)
NL (2)	NL185515C (sv)
NZ (1)	NZ183050A (sv)
SE (1)	SE435281B (sv)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH629493A5 (en) *	1976-05-11	1982-04-30	Wellcome Found	Processes for preparing novel prostaglandin derivatives
GB1583961A (en) *	1976-05-11	1981-02-04	Wellcome Found	Prostacyclin and derivatives thereof
GB1595056A (en) *	1976-10-12	1981-08-05	Wellcome Found	Pharmaceutical combination
AU511711B2 (en) *	1976-12-30	1980-09-04	Upjohn Company, The	6-Oxo and 5, 6-Dihalo prostaglandin analogues
FI71138C (fi) *	1976-12-31	1986-11-24	Erba Farmitalia	Foerfarande foer framstaellning av terapeutiskt aktiva bisykliska prostaglandiner
AU524786B2 (en) *	1977-03-07	1982-10-07	The Upjohn Company	Prostacyclins
JPS53136513A (en) *	1977-05-06	1978-11-29	Ono Pharmaceut Co Ltd	Stabilization of prostaglandin-x-related compounds
JPS6022710B2 (ja) *	1977-09-16	1985-06-03	小野薬品工業株式会社	プロスタグランジン類似化合物
DE2743283A1 (de) *	1977-09-27	1979-04-05	Hoechst Ag	Neue prostacyclin-analoga
IT1088036B (it)	1977-11-25	1985-06-04	Erba Carlo Spa	15-epi-prostaciclina e prostaciclina analoghi
US4705806A (en) *	1978-02-13	1987-11-10	Morton Jr Douglas R	Prostacyclin analogs
DE2811950A1 (de) *	1978-03-18	1979-12-13	Hoechst Ag	Neue analoga von prostacyclin
IT1099575B (it) *	1978-07-20	1985-09-18	Erba Carlo Spa	20-metil-13,14-deidro-pgi2' suoi sali e suoi 16s- e 16r-metil derivati
DE2834248A1 (de) *	1978-08-04	1980-02-28	Hoechst Ag	Neue prostaglandinderivate in der delta 2-pgf tief 2 und delta 2-pge tief 2 -reihe
US4180657A (en) *	1978-08-14	1979-12-25	The Upjohn Company	Acyl-substituted phenyl esters of prostacyclin-type compounds
JPS56122372A (en) *	1980-03-03	1981-09-25	Toray Ind Inc	Prostaglandin i2 derivative
DE3029984C2 (de) *	1980-08-08	1983-12-15	Grünenthal GmbH, 5190 Stolberg	2-Oxabicyclo [3.3.0] octanderivate und diese enthaltende Arzneimittel
CH648556A5 (de) *	1981-03-11	1985-03-29	Hoffmann La Roche	Fluorprostacycline.
JPS595155A (ja) *	1982-06-30	1984-01-12	Ono Pharmaceut Co Ltd	プロスタグランジンｄ類似化合物
US5591887A (en) *	1987-04-30	1997-01-07	R-Tech Ueno, Ltd.	Prostaglandins of the F series
US5221763A (en) *	1987-04-30	1993-06-22	R-Tech Ueno, Ltd.	Prostaglandins of the F series
CA1324129C (en) *	1987-04-30	1993-11-09	Ryuzo Ueno	Prostaglandins of the f series
US5185374A (en) *	1988-05-11	1993-02-09	K.K. Ueno Seiyaku Oyo Kenkyujo	Use of 15-ketoprostaglandin E or F compounds for uterine contraction
AU619543B2 (en) *	1988-05-11	1992-01-30	Sucampo Ag	Use of 15-ketoprostaglandin e or f compounds for uterine contraction
WO2011013651A1 (ja)	2009-07-28	2011-02-03	小野薬品工業株式会社	二環式化合物およびその医薬用途
EP2669279B1 (en)	2011-01-27	2017-01-11	ONO Pharmaceutical Co., Ltd.	Bicyclic compound and use thereof for medical purposes
CN116143742B (zh) *	2023-02-27	2024-10-18	广州楷石生物科技有限公司	依前列醇一氧化氮供体药物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2351112A1 (fr) *	1975-10-21	1977-12-09	Wellcome Found	Derive de prostaglandine et medicament contenant ce derive
CH629493A5 (en) *	1976-05-11	1982-04-30	Wellcome Found	Processes for preparing novel prostaglandin derivatives
MX4813E (es) *	1976-06-01	1982-10-19	Upjohn Co	Procedimiento para preparar analogos de prostaglandinas
AU511711B2 (en) *	1976-12-30	1980-09-04	Upjohn Company, The	6-Oxo and 5, 6-Dihalo prostaglandin analogues

1976
- 1976-12-30 IL IL51189A patent/IL51189A/xx unknown
1977
- 1977-01-11 NZ NZ183050A patent/NZ183050A/xx unknown
- 1977-01-22 DE DE2702553A patent/DE2702553C2/de not_active Expired
- 1977-01-25 CA CA000270416A patent/CA1160627A/en not_active Expired
- 1977-01-27 GB GB3314/77A patent/GB1554044A/en not_active Expired
- 1977-01-28 NL NLAANVRAGE7700896,A patent/NL185515C/xx not_active IP Right Cessation
- 1977-02-01 SE SE7701045A patent/SE435281B/sv not_active IP Right Cessation
- 1977-02-03 JP JP52010332A patent/JPS5936911B2/ja not_active Expired
- 1977-02-03 FR FR7703076A patent/FR2359125B1/fr not_active Expired
- 1977-02-04 CH CH141677A patent/CH632245A5/de not_active IP Right Cessation
- 1977-02-04 BE BE174693A patent/BE851122A/xx not_active IP Right Cessation
- 1977-10-26 FR FR7732282A patent/FR2362833A1/fr active Granted
- 1977-10-26 FR FR7732283A patent/FR2362834A1/fr active Granted
- 1977-11-04 MX MX775413U patent/MX4811E/es unknown
1978
- 1978-10-26 CA CA000349870A patent/CA1179335A/en not_active Expired
- 1978-10-26 CA CA000349868A patent/CA1160628A/en not_active Expired
1982
- 1982-04-02 CH CH206082A patent/CH637949A5/de not_active IP Right Cessation
1983
- 1983-07-01 NL NL8300921A patent/NL8300921A/nl not_active Application Discontinuation
1985
- 1985-01-31 HK HK93/85A patent/HK9385A/xx unknown

Also Published As

Publication number	Publication date
CH632245A5 (en)	1982-09-30
FR2362834A1 (fr)	1978-03-24
CA1160628A (en)	1984-01-17
NL7700896A (nl)	1977-08-08
IL51189A0 (en)	1977-02-28
FR2362834B1 (sv)	1980-08-08
CA1160627A (en)	1984-01-17
FR2362833A1 (fr)	1978-03-24
CH637949A5 (en)	1983-08-31
NL185515C (nl)	1990-05-01
NL8300921A (nl)	1983-07-01
FR2359125B1 (fr)	1985-11-15
GB1554044A (en)	1979-10-17
NL185515B (nl)	1989-12-01
JPS5295644A (en)	1977-08-11
NZ183050A (en)	1979-06-08
FR2359125A1 (fr)	1978-02-17
JPS5936911B2 (ja)	1984-09-06
MX4811E (es)	1982-10-19
HK9385A (en)	1985-02-08
CA1179335A (en)	1984-12-11
SE7701045L (sv)	1977-08-05
DE2702553C2 (de)	1986-02-20
FR2362833B1 (sv)	1980-08-08
BE851122A (fr)	1977-08-04
IL51189A (en)	1985-08-30
DE2702553A1 (de)	1977-08-18

Publication	Publication Date	Title
SE435281B (sv)	1984-09-17	Forfarande for framstellning av prostaglandinderivat
SE441827B (sv)	1985-11-11	Forfarande for framstellning av fenoxiaminopropanoler
SE7700032L (sv)	1977-07-06	Framstellning av n-fosfonometylglysin
NO774404L (no)	1978-06-26	Fremgangsmaate for fremstilling av dimetyleter
SE441354B (sv)	1985-09-30	Forfarande for framstellning av meta-fenoxibensaldehyd
SE435387B (sv)	1984-09-24	Forfarande for framstellning av antracyklinglykosider
NO143992C (no)	1981-05-27	Fremgangsmaate for fremstilling av heksanitrostilben
SE437833B (sv)	1985-03-18	Forfarande for framstellning av 7-beta-oxiiminoacylcefalosporiner
NO834236L (no)	1978-02-03	Fremgangsmaate for fremstilling av 4-halogen-dihydropyran-derivater
SE436647B (sv)	1985-01-14	Forfarande for framstellning av prostaglandinderivat (prostacyclin)
SE431207B (sv)	1984-01-23	Forfarande for framstellning av tiazolidinderivat
SE435510B (sv)	1984-10-01	Analogiforfarande for framstellning av 3-fluor-6-piperazinylmorfantridiner
SE7707621L (sv)	1978-01-02	Forfarande for framstellning av xyloslosning
SE7707407L (sv)	1977-12-29	Forfarande for framstellning av cefamderivat
SE7707471L (sv)	1978-01-17	Forfarande for framstellning av 5-m-tolyloxiuracil
NO774067L (no)	1978-06-13	Fremgangsmaate for fremstilling av cellulosemasse
NO139555C (no)	1979-04-04	Fremgangsmaate for fremstilling av fosgen
SE7712218L (sv)	1978-05-03	Forfarande for framstellning av 4a-aryloktahydro-1h-2-pyrindiner
SE431450B (sv)	1984-02-06	Mellanprodukt till anvendning for framstellning av prostaglandinderivat
SE7706262L (sv)	1977-11-29	Forfarande for framstellning av kvadratsyra
RO77308A (ro)	1981-08-17	Procedeu pentru prepararea derivatiilor aminochinazolinei substituite
SE7702071L (sv)	1977-08-26	Forfarande for framstellning av sulfoacetaler
SE7709142L (sv)	1978-02-22	Forfarande for framstellning av 1-aryloxi-3-amino-propan-2-oler
SE428016B (sv)	1983-05-30	Forfarande for framstellning av 6a,10a-cis - hexahydrodibensopyranonderivat
SE427109B (sv)	1983-03-07	Forfarande for framstellning av 16-fluorsubstituerade prostaglandinderivat

Legal Events

Date	Code	Title	Description
1995-01-31	NUG	Patent has lapsed	Ref document number: 7701045-2 Effective date: 19880125 Format of ref document f/p: F

Date

Code

Title

Description

1995-01-31

NUG

Patent has lapsed

Ref document number: 7701045-2

Effective date: 19880125

Format of ref document f/p: F