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RU93058260A - Способ получения водорастворимых микронизированных веществ - Google Patents

Способ получения водорастворимых микронизированных веществ

Info

Publication number
RU93058260A
RU93058260A RU93058260/14A RU93058260A RU93058260A RU 93058260 A RU93058260 A RU 93058260A RU 93058260/14 A RU93058260/14 A RU 93058260/14A RU 93058260 A RU93058260 A RU 93058260A RU 93058260 A RU93058260 A RU 93058260A
Authority
RU
Russia
Prior art keywords
substances
producing water
micronized
micronized substances
soluble
Prior art date
Application number
RU93058260/14A
Other languages
English (en)
Other versions
RU2112507C1 (ru
Inventor
Трофаст Ян
Трофаст Эва
Бюстрем Катарина
Якуповиц Эдиб
Original Assignee
Актиеболагет Астра
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9101090A external-priority patent/SE9101090D0/xx
Application filed by Актиеболагет Астра filed Critical Актиеболагет Астра
Publication of RU93058260A publication Critical patent/RU93058260A/ru
Application granted granted Critical
Publication of RU2112507C1 publication Critical patent/RU2112507C1/ru

Links

Claims (1)

  1. Способ получения водорастворимых микронизированных веществ, которые можно получать, хранить и использовать, сохраняя аэродинамические свойства, необходимые для ингаляции таких веществ, осуществляется путем: а) в случае необходимости понижения содержания остаточной воды в микронизированном веществе путем высушивания необязательно при повышенной температуре и/или в вакууме; в) обработки высушенных микронизированных веществ растворителем и с) удаления остаточного растворителя путем выдерживания в сухом месте, например в вакууме, или путем продувки инертным газом.
RU93058260A 1991-04-11 1992-03-24 Способ получения стабильных водорастворимых микронизированных веществ RU2112507C1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9101090-0 1991-04-11
SE9101090A SE9101090D0 (sv) 1991-04-11 1991-04-11 Process for conditioning of water-soluble substances
PCT/SE1992/000186 WO1992018110A1 (en) 1991-04-11 1992-03-24 Process for conditioning of water-soluble substances

Publications (2)

Publication Number Publication Date
RU93058260A true RU93058260A (ru) 1996-10-10
RU2112507C1 RU2112507C1 (ru) 1998-06-10

Family

ID=20382434

Family Applications (1)

Application Number Title Priority Date Filing Date
RU93058260A RU2112507C1 (ru) 1991-04-11 1992-03-24 Способ получения стабильных водорастворимых микронизированных веществ

Country Status (28)

Country Link
US (1) US5562923A (ru)
EP (3) EP0680752B1 (ru)
JP (2) JP3400999B2 (ru)
KR (1) KR100216384B1 (ru)
AT (2) ATE137671T1 (ru)
AU (1) AU662519B2 (ru)
BG (1) BG61474B1 (ru)
CA (1) CA2106975C (ru)
CZ (1) CZ286936B6 (ru)
DE (2) DE69210601T2 (ru)
DK (2) DK0680752T3 (ru)
EE (1) EE02970B1 (ru)
ES (2) ES2086733T3 (ru)
FI (1) FI105388B (ru)
GR (1) GR3020602T3 (ru)
HK (1) HK52497A (ru)
HU (1) HU211116B (ru)
IE (1) IE921144A1 (ru)
IS (1) IS3834A (ru)
NO (1) NO311867B1 (ru)
PL (1) PL168232B1 (ru)
PT (1) PT680752E (ru)
RO (1) RO115779B1 (ru)
RU (1) RU2112507C1 (ru)
SE (1) SE9101090D0 (ru)
SG (1) SG43180A1 (ru)
SK (1) SK280310B6 (ru)
WO (1) WO1992018110A1 (ru)

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CN1090935C (zh) * 1995-02-28 2002-09-18 阿温蒂斯药物公司 哌啶子基烷醇化合物的药物组合物
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SE9700135D0 (sv) 1997-01-20 1997-01-20 Astra Ab New formulation
SE9700133D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
EP2036544B1 (en) * 1997-03-20 2016-12-28 Merck Sharp & Dohme Corp. Dosage form of powder agglomerates
US6503537B2 (en) 1997-03-20 2003-01-07 Schering Corporation Preparation of powder agglomerates
US6495167B2 (en) 1997-03-20 2002-12-17 Schering Corporation Preparation of powder agglomerates
CN1159012C (zh) * 1997-08-26 2004-07-28 阿旺蒂斯制药公司 用于组合哌啶子基烷醇-减充血剂的药物组合物
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
RS50182B (sr) * 1997-09-29 2009-05-06 Nektar Therapeutics, Perforisane mikročestice i postupci za njihovu primenu
FI105074B (fi) * 1997-12-31 2000-06-15 Leiras Oy Farmaseuttisen formulaation valmistusmenetelmä
US6287693B1 (en) 1998-02-25 2001-09-11 John Claude Savoir Stable shaped particles of crystalline organic compounds
SE9804000D0 (sv) 1998-11-23 1998-11-23 Astra Ab New composition of matter
GB9826284D0 (en) 1998-12-01 1999-01-20 Rhone Poulence Rorer Limited Process
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AR022695A1 (es) * 1999-01-28 2002-09-04 Schering Corp PORTADOR SoLIDO PARTICULADO Y MÉTODO PARA PROVEER CONTROL DE LA PARTICULADA PARA LA DISTRIBUCIoN DE TAMANO DE PARTíCULAS Y DE CONTENIDO AMORFO CONVERTIBLE DURANTE SU PREPARACION
US6623760B1 (en) 1999-01-28 2003-09-23 Schering Corporation Method of preparing particles for agglomeration
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
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US7244415B2 (en) 2002-03-28 2007-07-17 Boehringer Ingelheim Pharma Gmbh & Co. Kg HFA suspension formulations of an anhydrate
US20040028746A1 (en) * 2002-08-06 2004-02-12 Sonke Svenson Crystalline drug particles prepared using a controlled precipitation (recrystallization) process
GB0228826D0 (en) * 2002-12-11 2003-01-15 Okpala Joseph Hair technology in creating particles with improved delivery capabilities
WO2004087102A2 (en) * 2003-03-26 2004-10-14 Teva Pharmaceutical Industries Ltd. A process for preparing a pharmaceutical active ingredient with high specific surface area
EA018356B1 (ru) * 2003-06-13 2013-07-30 Джон Клод Савуар Микросферы эстрадиола и холестерина
GB0323684D0 (en) 2003-10-09 2003-11-12 Jagotec Ag Improvements in or relating to organic compounds
CN1894095A (zh) * 2003-10-17 2007-01-10 纳幕尔杜邦公司 箔对热塑性聚合物的粘合
US7544805B2 (en) 2004-02-03 2009-06-09 Chemagis Ltd. Stable amorphous forms of montelukast sodium
DE102004048390A1 (de) 2004-10-01 2006-04-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Pulverinhalativa auf Basis modifizierter Laktosemischungen als Hilfsstoff
DE102004048389A1 (de) 2004-10-01 2006-04-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Modifizierung von Oberflächen von Laktose als Hilfsstoff zur Verwendung für Pulverinhalativa
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