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RU2015148627A - METHOD FOR CONTROLING THE RELATIONSHIP OF RESOLUTION ABILITY BY MASS AND SENSITIVITY IN MULTI-REFLECT TIME-SPAN MASS SPECTROMETERS - Google Patents

METHOD FOR CONTROLING THE RELATIONSHIP OF RESOLUTION ABILITY BY MASS AND SENSITIVITY IN MULTI-REFLECT TIME-SPAN MASS SPECTROMETERS Download PDF

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Publication number
RU2015148627A
RU2015148627A RU2015148627A RU2015148627A RU2015148627A RU 2015148627 A RU2015148627 A RU 2015148627A RU 2015148627 A RU2015148627 A RU 2015148627A RU 2015148627 A RU2015148627 A RU 2015148627A RU 2015148627 A RU2015148627 A RU 2015148627A
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RU
Russia
Prior art keywords
mass
sensitivity
ion
controling
relationship
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RU2015148627A
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Russian (ru)
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RU2660655C2 (en
Inventor
Николай Васильевич Краснов
Тимофей Вячеславович Помозов
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Общество с ограниченной ответственностью "Альфа" (ООО "Альфа")
Общество с ограниченной ответственностью "Биотехнологические аналитические приборы" (ООО "БиАП")
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Priority to RU2015148627A priority Critical patent/RU2660655C2/en
Publication of RU2015148627A publication Critical patent/RU2015148627A/en
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Publication of RU2660655C2 publication Critical patent/RU2660655C2/en

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    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/40—Time-of-flight spectrometers

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  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)

Claims (1)

Способ управления соотношением разрешающей способности по массе и чувствительности в многоотражательных времяпролётных масс-спектрометрах, основанный на формировании периодически поворачиваемых ионных траекторий с помощью ионно-оптических элементов с постоянными электрическими напряжениями, отличающийся тем, что количество оборотов ионных траекторий определяется управляемой энергией ионных пакетов в направлении дрейфа, ортогональном направлению их импульсного выталкивания, при этом соотношение кинетических энергий ионных пакетов в направлении дрейфа и в направлении их импульсного выталкивания соответствует целому количеству оборотов ионных траекторий с сохранением анализируемого массового диапазона. A method for controlling the ratio of mass resolution and sensitivity in multi-reflection time-of-flight mass spectrometers based on the formation of periodically rotated ion trajectories using ion-optical elements with constant electric voltages, characterized in that the number of revolutions of the ion trajectories is determined by the controlled energy of the ion packets in the direction of drift orthogonal to the direction of their pulse repulsion, with the ratio of kinetic energies of ionic pac comrade in the drift direction and in the direction of ejection pulse corresponds to an integral number of revolutions of the ion trajectories with preservation analyte mass range.
RU2015148627A 2015-11-12 2015-11-12 Method of controlling relation of resolution ability by weight and sensitivity in multi-reflective time-of-flight mass-spectrometers RU2660655C2 (en)

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RU2015148627A RU2660655C2 (en) 2015-11-12 2015-11-12 Method of controlling relation of resolution ability by weight and sensitivity in multi-reflective time-of-flight mass-spectrometers

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RU2015148627A RU2660655C2 (en) 2015-11-12 2015-11-12 Method of controlling relation of resolution ability by weight and sensitivity in multi-reflective time-of-flight mass-spectrometers

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RU2015148627A true RU2015148627A (en) 2017-05-23
RU2660655C2 RU2660655C2 (en) 2018-07-09

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Cited By (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019215428A1 (en) * 2018-05-10 2019-11-14 Micromass Uk Limited Multi-reflecting time of flight mass analyser
US10593533B2 (en) 2015-11-16 2020-03-17 Micromass Uk Limited Imaging mass spectrometer
US10629425B2 (en) 2015-11-16 2020-04-21 Micromass Uk Limited Imaging mass spectrometer
US10636646B2 (en) 2015-11-23 2020-04-28 Micromass Uk Limited Ion mirror and ion-optical lens for imaging
US10741376B2 (en) 2015-04-30 2020-08-11 Micromass Uk Limited Multi-reflecting TOF mass spectrometer
US10950425B2 (en) 2016-08-16 2021-03-16 Micromass Uk Limited Mass analyser having extended flight path
US11049712B2 (en) 2017-08-06 2021-06-29 Micromass Uk Limited Fields for multi-reflecting TOF MS
US11081332B2 (en) 2017-08-06 2021-08-03 Micromass Uk Limited Ion guide within pulsed converters
US11205568B2 (en) 2017-08-06 2021-12-21 Micromass Uk Limited Ion injection into multi-pass mass spectrometers
US11211238B2 (en) 2017-08-06 2021-12-28 Micromass Uk Limited Multi-pass mass spectrometer
US11239067B2 (en) 2017-08-06 2022-02-01 Micromass Uk Limited Ion mirror for multi-reflecting mass spectrometers
US11295944B2 (en) 2017-08-06 2022-04-05 Micromass Uk Limited Printed circuit ion mirror with compensation
US11309175B2 (en) 2017-05-05 2022-04-19 Micromass Uk Limited Multi-reflecting time-of-flight mass spectrometers
US11328920B2 (en) 2017-05-26 2022-05-10 Micromass Uk Limited Time of flight mass analyser with spatial focussing
US11367608B2 (en) 2018-04-20 2022-06-21 Micromass Uk Limited Gridless ion mirrors with smooth fields
US11587779B2 (en) 2018-06-28 2023-02-21 Micromass Uk Limited Multi-pass mass spectrometer with high duty cycle
US11621156B2 (en) 2018-05-10 2023-04-04 Micromass Uk Limited Multi-reflecting time of flight mass analyser
US11817303B2 (en) 2017-08-06 2023-11-14 Micromass Uk Limited Accelerator for multi-pass mass spectrometers
US11848185B2 (en) 2019-02-01 2023-12-19 Micromass Uk Limited Electrode assembly for mass spectrometer
US11881387B2 (en) 2018-05-24 2024-01-23 Micromass Uk Limited TOF MS detection system with improved dynamic range

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1725289A1 (en) * 1989-07-20 1992-04-07 Институт Ядерной Физики Ан Казсср Time-of-flight mass spectrometer with multiple reflection
CN101366097B (en) * 2005-10-11 2015-09-16 莱克公司 There is the multiple reflections time-of-flight mass spectrometer of orthogonal acceleration
GB0620398D0 (en) * 2006-10-13 2006-11-22 Shimadzu Corp Multi-reflecting time-of-flight mass analyser and a time-of-flight mass spectrometer including the time-of-flight mass analyser
US9048080B2 (en) * 2010-08-19 2015-06-02 Leco Corporation Time-of-flight mass spectrometer with accumulating electron impact ion source

Cited By (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10741376B2 (en) 2015-04-30 2020-08-11 Micromass Uk Limited Multi-reflecting TOF mass spectrometer
US10593533B2 (en) 2015-11-16 2020-03-17 Micromass Uk Limited Imaging mass spectrometer
US10629425B2 (en) 2015-11-16 2020-04-21 Micromass Uk Limited Imaging mass spectrometer
US10636646B2 (en) 2015-11-23 2020-04-28 Micromass Uk Limited Ion mirror and ion-optical lens for imaging
US10950425B2 (en) 2016-08-16 2021-03-16 Micromass Uk Limited Mass analyser having extended flight path
US11309175B2 (en) 2017-05-05 2022-04-19 Micromass Uk Limited Multi-reflecting time-of-flight mass spectrometers
US11328920B2 (en) 2017-05-26 2022-05-10 Micromass Uk Limited Time of flight mass analyser with spatial focussing
US11295944B2 (en) 2017-08-06 2022-04-05 Micromass Uk Limited Printed circuit ion mirror with compensation
US11081332B2 (en) 2017-08-06 2021-08-03 Micromass Uk Limited Ion guide within pulsed converters
US11205568B2 (en) 2017-08-06 2021-12-21 Micromass Uk Limited Ion injection into multi-pass mass spectrometers
US11211238B2 (en) 2017-08-06 2021-12-28 Micromass Uk Limited Multi-pass mass spectrometer
US11239067B2 (en) 2017-08-06 2022-02-01 Micromass Uk Limited Ion mirror for multi-reflecting mass spectrometers
US11817303B2 (en) 2017-08-06 2023-11-14 Micromass Uk Limited Accelerator for multi-pass mass spectrometers
US11049712B2 (en) 2017-08-06 2021-06-29 Micromass Uk Limited Fields for multi-reflecting TOF MS
US11756782B2 (en) 2017-08-06 2023-09-12 Micromass Uk Limited Ion mirror for multi-reflecting mass spectrometers
US11367608B2 (en) 2018-04-20 2022-06-21 Micromass Uk Limited Gridless ion mirrors with smooth fields
US11342175B2 (en) 2018-05-10 2022-05-24 Micromass Uk Limited Multi-reflecting time of flight mass analyser
US11621156B2 (en) 2018-05-10 2023-04-04 Micromass Uk Limited Multi-reflecting time of flight mass analyser
CN112106172A (en) * 2018-05-10 2020-12-18 英国质谱公司 Multi-reflection time-of-flight mass analyser
WO2019215428A1 (en) * 2018-05-10 2019-11-14 Micromass Uk Limited Multi-reflecting time of flight mass analyser
CN112106172B (en) * 2018-05-10 2024-06-07 英国质谱公司 Multi-reflection time-of-flight mass analyzer
US11881387B2 (en) 2018-05-24 2024-01-23 Micromass Uk Limited TOF MS detection system with improved dynamic range
US11587779B2 (en) 2018-06-28 2023-02-21 Micromass Uk Limited Multi-pass mass spectrometer with high duty cycle
US11848185B2 (en) 2019-02-01 2023-12-19 Micromass Uk Limited Electrode assembly for mass spectrometer

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Publication number Publication date
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MM4A The patent is invalid due to non-payment of fees

Effective date: 20180203