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PT951473E - Novos derivados da ciclosporina sua preparacao e composicoes farmaceuticas que os contem - Google Patents

Novos derivados da ciclosporina sua preparacao e composicoes farmaceuticas que os contem

Info

Publication number
PT951473E
PT951473E PT97952997T PT97952997T PT951473E PT 951473 E PT951473 E PT 951473E PT 97952997 T PT97952997 T PT 97952997T PT 97952997 T PT97952997 T PT 97952997T PT 951473 E PT951473 E PT 951473E
Authority
PT
Portugal
Prior art keywords
ciclosporin
contain
preparation
pharmaceutical compositions
new derivatives
Prior art date
Application number
PT97952997T
Other languages
English (en)
Inventor
Serge Mignani
Jean-Claude Barriere
Georges Bashiardes
Jean-Christophe Carry
Michel Evers
Bruno Filoche
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of PT951473E publication Critical patent/PT951473E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64Cyclic peptides containing only normal peptide links
    • C07K7/645Cyclosporins; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PT97952997T 1996-12-24 1997-12-23 Novos derivados da ciclosporina sua preparacao e composicoes farmaceuticas que os contem PT951473E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9615954A FR2757520B1 (fr) 1996-12-24 1996-12-24 Derive de cyclosporine, sa preparation et les compositions pharmaceutiques qui le contiennent

Publications (1)

Publication Number Publication Date
PT951473E true PT951473E (pt) 2002-11-29

Family

ID=9499087

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97952997T PT951473E (pt) 1996-12-24 1997-12-23 Novos derivados da ciclosporina sua preparacao e composicoes farmaceuticas que os contem

Country Status (11)

Country Link
US (1) US5948755A (pt)
EP (1) EP0951473B1 (pt)
JP (1) JP4104666B2 (pt)
AT (1) ATE218581T1 (pt)
AU (1) AU5669198A (pt)
DE (1) DE69713151D1 (pt)
DK (1) DK0951473T3 (pt)
ES (1) ES2178036T3 (pt)
FR (1) FR2757520B1 (pt)
PT (1) PT951473E (pt)
WO (1) WO1998028328A1 (pt)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1086124B1 (en) * 1998-06-12 2003-11-19 C-Chem AG Novel cyclosporins
DE69928938T2 (de) 1998-07-01 2006-08-17 Debiopharm S.A. Neues cyclosporin mit verbesserter wirkung
US6254860B1 (en) 1999-04-13 2001-07-03 Allergan Sales, Inc. Ocular treatment using cyclosporin-A derivatives
EP1435910B9 (en) * 2001-10-19 2010-02-03 Isotechnika Inc. Novel cyclosporin analog microemulsion preconcentrates
CA2461740C (en) 2001-10-19 2013-02-12 Isotechnika Inc. Synthesis of cyclosporin analogs
KR100512019B1 (ko) * 2002-07-25 2005-09-02 신득용 사이클로스포린 a 또는 이의 유도체를 이용한 세포의노화를 억제하는 방법 및 배양배지
GB0320638D0 (en) 2003-09-03 2003-10-01 Novartis Ag Organic compounds
JP2007513154A (ja) * 2003-12-08 2007-05-24 サイトキネティクス・インコーポレーテッド 化合物、組成物及び方法
AU2005292162B2 (en) * 2004-10-01 2011-11-10 Scynexis, Inc 3-ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis C infection
US7196161B2 (en) 2004-10-01 2007-03-27 Scynexis Inc. 3-ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis C infection
UA88484C2 (ru) 2004-10-01 2009-10-26 Дебиофарм Са ПРИМЕНЕНИЕ [D-MeAla]3-[EtVal]4-ЦИКЛОСПОРИНА ДЛЯ ЛЕЧЕНИЯ ИНФЕКЦИИ ГЕПАТИТА С И ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, КОТОРАЯ ВКЛЮЧАЕТ [D-MeAla]3-[EtVal]4-ЦИКЛОСПОРИН
JP5517454B2 (ja) 2005-09-30 2014-06-11 スシネキス インク C型肝炎感染の治療及び予防のための方法及び医薬組成物
CA2623864C (en) 2005-09-30 2014-12-16 Scynexis, Inc. Arylalkyl and heteroarylalkyl derivatives of cyclosporine a for the treatment and prevention of viral infection
US7696165B2 (en) 2006-03-28 2010-04-13 Albany Molecular Research, Inc. Use of cyclosporin alkyne analogues for preventing or treating viral-induced disorders
US7696166B2 (en) 2006-03-28 2010-04-13 Albany Molecular Research, Inc. Use of cyclosporin alkyne/alkene analogues for preventing or treating viral-induced disorders
DK2023918T3 (da) 2006-05-19 2011-04-26 Scynexis Inc Cyclosporiner til behandlingen og forebyggelse af okulære lidelser
JP2009539292A (ja) * 2006-06-02 2009-11-12 ぺリション、クロード、アニー 活性電子の管理
US7576057B2 (en) 2006-11-20 2009-08-18 Scynexis, Inc. Cyclic peptides
US20080255038A1 (en) * 2007-04-11 2008-10-16 Samuel Earl Hopkins Pharmaceutical compositions
US8394763B2 (en) 2007-09-26 2013-03-12 Oregon Health & Science University Cyclic undecapeptides and derivatives as multiple sclerosis therapies
US9090671B2 (en) 2008-06-06 2015-07-28 Scynexis, Inc. Macrocyclic peptides
WO2009148615A1 (en) * 2008-06-06 2009-12-10 Scynexis, Inc. Cyclosporin analogs and their use in the treatment of hcv infections
KR20110031973A (ko) * 2008-07-10 2011-03-29 알러간, 인코포레이티드 눈 및 피부의 질환 및 상태를 치료하기 위한 사이클로스포린 유도체
WO2010076329A1 (en) 2008-12-31 2010-07-08 Scynexis, Inc. Derivatives of cyclosporin a
EP2435065A1 (en) * 2009-05-27 2012-04-04 Allergan, Inc. Cyclosporin derivatives for treating inflammatory diseases and conditions
KR101149529B1 (ko) 2009-09-11 2012-05-25 한국화학연구원 인덴온 유도체 및 이를 포함하는 약학적 조성물
KR20120125610A (ko) 2009-12-30 2012-11-16 싸이넥시스, 인크. 시클로스포린 유사체
RU2630690C9 (ru) 2010-12-15 2017-12-28 КонтраВир Фармасьютикалз, Инк. МОЛЕКУЛЫ АНАЛОГОВ ЦИКЛОСПОРИНА, МОДИФИЦИРОВАННЫЕ ПО 1 и 3 АМИНОКИСЛОТЕ
US9395551B2 (en) 2013-04-24 2016-07-19 Kamakura Koki Co., Ltd. Optical image stabilizer
WO2018191579A1 (en) * 2017-04-14 2018-10-18 Contravir Pharmaceuticals, Inc. Combination therapy for treating viral infections

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0194972B1 (en) * 1985-03-11 1992-07-29 Sandoz Ag Novel cyclosporins
US4814323A (en) * 1986-03-25 1989-03-21 Andrieu J M Process for the treatment and the prevention of AIDS and other disorders induced by the LAV/HTLV III virus
DK0484281T4 (da) * 1990-11-02 2001-02-05 Novartis Ag Cyclosporiner
PL324531A1 (en) * 1995-07-17 1998-06-08 Chem Ag C Derivatives of cyclosporin effective against hiv virus

Also Published As

Publication number Publication date
FR2757520A1 (fr) 1998-06-26
US5948755A (en) 1999-09-07
FR2757520B1 (fr) 1999-01-29
DE69713151D1 (de) 2002-07-11
WO1998028328A1 (fr) 1998-07-02
EP0951473B1 (fr) 2002-06-05
JP4104666B2 (ja) 2008-06-18
ATE218581T1 (de) 2002-06-15
DK0951473T3 (da) 2002-09-16
EP0951473A1 (fr) 1999-10-27
JP2001507016A (ja) 2001-05-29
ES2178036T3 (es) 2002-12-16
AU5669198A (en) 1998-07-17

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