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PL419748A1 - 3'-Amino-4-benzyloxychalcone and method for obtaining 3'-amino-4-benzyloxychalcone - Google Patents

3'-Amino-4-benzyloxychalcone and method for obtaining 3'-amino-4-benzyloxychalcone

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Publication number
PL419748A1
PL419748A1 PL419748A PL41974816A PL419748A1 PL 419748 A1 PL419748 A1 PL 419748A1 PL 419748 A PL419748 A PL 419748A PL 41974816 A PL41974816 A PL 41974816A PL 419748 A1 PL419748 A1 PL 419748A1
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PL
Poland
Prior art keywords
benzyloxychalcone
amino
formula
substrate
organic solvent
Prior art date
Application number
PL419748A
Other languages
Polish (pl)
Other versions
PL228432B1 (en
Inventor
Joanna Kozłowska
Mirosław Anioł
Original Assignee
Uniwersytet Przyrodniczy we Wrocławiu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Uniwersytet Przyrodniczy we Wrocławiu filed Critical Uniwersytet Przyrodniczy we Wrocławiu
Priority to PL419748A priority Critical patent/PL228432B1/en
Publication of PL419748A1 publication Critical patent/PL419748A1/en
Publication of PL228432B1 publication Critical patent/PL228432B1/en

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Zgłoszony sposób polega na tym, że do substratu, którym jest 3'-aminoacetofenon o wzorze 1 dodaje się co najmniej jeden rozpuszczalnik organiczny, charakterystyczny dla pochodnych acetofenonów, wodorotlenek oraz drugi substrat, którym jest 4-benzyloksybenzaldehyd o wzorze 2, co stanowi mieszaninę reakcyjną, którą zabezpiecza się przed dostępem światła i pozostawia w temperaturze od 20°C do 30°C na okres 1 do 2 godzin przy ciągłym mieszaniu, po czym przereagowaną mieszaninę wylewa się do schłodzonej wody, a następnie prowadzi się ekstrakcję rozpuszczalnikiem organicznym niemieszającym się z wodą, osusza bezwodnym siarczanem magnezu i/lub bezwodnym siarczanem sodu, a rozpuszczalnik odparowuje się, następnie otrzymany ekstrakt oczyszcza się. Zgłoszenie obejmuje też 3'-amino-n benzyloksychalkon o wzorze 3.The notified method consists in adding to the substrate which is 3'-aminoacetophenone of formula 1 at least one organic solvent characteristic of acetophenone derivatives, hydroxide and a second substrate which is 4-benzyloxybenzaldehyde of formula 2, which is a reaction mixture , which is protected from light and left at a temperature of 20 ° C to 30 ° C for 1 to 2 hours with continuous stirring, after which the reacted mixture is poured into chilled water, followed by extraction with a water-immiscible organic solvent , dried over anhydrous magnesium sulfate and / or anhydrous sodium sulfate, and the solvent is evaporated, then the obtained extract is purified. The application also includes 3'-amino-n benzyloxychalcone of formula 3.

PL419748A 2016-12-09 2016-12-09 3'-Amino-4-benzyloxychalcone and method for obtaining 3'-amino-4-benzyloxychalcone PL228432B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL419748A PL228432B1 (en) 2016-12-09 2016-12-09 3'-Amino-4-benzyloxychalcone and method for obtaining 3'-amino-4-benzyloxychalcone

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL419748A PL228432B1 (en) 2016-12-09 2016-12-09 3'-Amino-4-benzyloxychalcone and method for obtaining 3'-amino-4-benzyloxychalcone

Publications (2)

Publication Number Publication Date
PL419748A1 true PL419748A1 (en) 2017-06-19
PL228432B1 PL228432B1 (en) 2018-03-30

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Family Applications (1)

Application Number Title Priority Date Filing Date
PL419748A PL228432B1 (en) 2016-12-09 2016-12-09 3'-Amino-4-benzyloxychalcone and method for obtaining 3'-amino-4-benzyloxychalcone

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PL (1) PL228432B1 (en)

Also Published As

Publication number Publication date
PL228432B1 (en) 2018-03-30

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