PL3049439T3 - Bispecyficzne nanociała - Google Patents
Bispecyficzne nanociałaInfo
- Publication number
- PL3049439T3 PL3049439T3 PL14777078T PL14777078T PL3049439T3 PL 3049439 T3 PL3049439 T3 PL 3049439T3 PL 14777078 T PL14777078 T PL 14777078T PL 14777078 T PL14777078 T PL 14777078T PL 3049439 T3 PL3049439 T3 PL 3049439T3
- Authority
- PL
- Poland
- Prior art keywords
- bispecific nanobodies
- nanobodies
- bispecific
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2812—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3007—Carcino-embryonic Antigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/22—Immunoglobulins specific features characterized by taxonomic origin from camelids, e.g. camel, llama or dromedary
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/32—Immunoglobulins specific features characterized by aspects of specificity or valency specific for a neo-epitope on a complex, e.g. antibody-antigen or ligand-receptor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Oncology (AREA)
- Cell Biology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361882877P | 2013-09-26 | 2013-09-26 | |
PCT/EP2014/070692 WO2015044386A1 (en) | 2013-09-26 | 2014-09-26 | Bispecific nanobodies |
EP14777078.8A EP3049439B1 (en) | 2013-09-26 | 2014-09-26 | Bispecific nanobodies |
Publications (1)
Publication Number | Publication Date |
---|---|
PL3049439T3 true PL3049439T3 (pl) | 2020-07-13 |
Family
ID=51627294
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL14777078T PL3049439T3 (pl) | 2013-09-26 | 2014-09-26 | Bispecyficzne nanociała |
Country Status (10)
Country | Link |
---|---|
US (2) | US20160251440A1 (pl) |
EP (1) | EP3049439B1 (pl) |
JP (1) | JP6721503B2 (pl) |
CN (2) | CN115160441A (pl) |
AU (1) | AU2014326674B2 (pl) |
CA (1) | CA2925061C (pl) |
ES (1) | ES2779123T3 (pl) |
PL (1) | PL3049439T3 (pl) |
PT (1) | PT3049439T (pl) |
WO (1) | WO2015044386A1 (pl) |
Families Citing this family (66)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2814962T3 (es) | 2013-02-20 | 2021-03-29 | Novartis Ag | Fijación eficaz como objetivo de la leucemia humana primaria utilizando células T modificadas con receptor de antígeno quimérico anti-CD123 |
CN107108744B (zh) | 2014-08-19 | 2020-09-25 | 诺华股份有限公司 | 抗cd123嵌合抗原受体(car)用于癌症治疗 |
CN107667113B (zh) * | 2015-02-05 | 2022-05-03 | 埃博灵克斯股份有限公司 | 通过c端改造的半胱氨酸连接的纳米抗体二聚体 |
JP7163028B2 (ja) * | 2015-05-13 | 2022-10-31 | アブリンクス エン.ヴェー. | Cd3反応性に基づくt細胞リクルートポリペプチド |
IL274151B (en) | 2015-05-21 | 2022-07-01 | Harpoon Therapeutics Inc | Trispecific binding proteins and methods of use |
CA2989321A1 (en) | 2015-06-29 | 2017-01-05 | Immunogen, Inc. | Anti-cd123 antibodies and conjugates and derivatives thereof |
EP3349795B1 (en) * | 2015-09-17 | 2021-03-17 | The Scripps Research Institute | Dual variable domain immunoconjugates and uses thereof |
UA121914C2 (uk) * | 2015-11-18 | 2020-08-10 | Мерк Шарп І Доум Корп. | Молекула, що зв'язує pd1 і lag3 |
JP6768800B2 (ja) | 2015-11-18 | 2020-10-14 | メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. | Ctla4結合性物質 |
CN109071639B (zh) * | 2015-11-18 | 2022-07-08 | 默沙东公司 | Pd1/ctla4结合剂 |
EP3932945A1 (en) | 2015-11-27 | 2022-01-05 | Ablynx NV | Polypeptides inhibiting cd40l |
US11623958B2 (en) | 2016-05-20 | 2023-04-11 | Harpoon Therapeutics, Inc. | Single chain variable fragment CD3 binding proteins |
EA201892693A1 (ru) | 2016-05-20 | 2019-04-30 | Харпун Терапьютикс, Инк. | Белки, содержащие одноцепочечный вариабельный фрагмент, связывающийся с cd3 |
SG11201810327XA (en) | 2016-05-20 | 2018-12-28 | Harpoon Therapeutics Inc | Single domain serum albumin binding protein |
CN117700549A (zh) * | 2016-11-16 | 2024-03-15 | 埃博灵克斯股份有限公司 | 能够结合CD123和TCRα/β的T细胞募集多肽 |
WO2018094282A1 (en) * | 2016-11-18 | 2018-05-24 | The Regents Of The University Of California | Engineered antibodies and uses thereof |
CN110198955A (zh) | 2016-11-23 | 2019-09-03 | 哈普恩治疗公司 | 前列腺特异性膜抗原结合蛋白质 |
KR20190087539A (ko) * | 2016-11-23 | 2019-07-24 | 하푼 테라퓨틱스, 인크. | Psma 표적화 삼중특이성 단백질 및 사용 방법 |
RU2658764C1 (ru) * | 2016-12-19 | 2018-06-22 | Федеральное государственное бюджетное учреждение науки институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова Российской академии наук (ИБХ РАН) | Селективный бифункциональный препарат на основе фрагментов одноцепочечных антител верблюжьих, нацеленный на опухолевые рецепторы cd47/cd44, предназначенный для терапии злокачественных новообразований |
WO2018160754A2 (en) | 2017-02-28 | 2018-09-07 | Harpoon Therapeutics, Inc. | Inducible monovalent antigen binding protein |
US20210260162A1 (en) * | 2017-03-31 | 2021-08-26 | The Board Of Trustees Of The Leland Stanford Junior University | Synthekine compositions and methods of use |
US20210115158A1 (en) * | 2017-04-03 | 2021-04-22 | Georgia Tech Research Corporation | Synthetic Particle Antibody Compositions And Uses Thereof |
CA3063362A1 (en) | 2017-05-12 | 2018-11-15 | Harpoon Therapeutics, Inc. | Msln targeting trispecific proteins and methods of use |
BR112019023855B1 (pt) | 2017-05-12 | 2021-11-30 | Harpoon Therapeutics, Inc | Proteínas de ligação à mesotelina |
AU2018277343A1 (en) | 2017-06-02 | 2020-01-02 | Ablynx N.V. | Adamts binding immunoglobulins |
CN111465612B (zh) | 2017-10-13 | 2024-08-27 | 哈普恩治疗公司 | B细胞成熟抗原结合蛋白 |
CA3078969A1 (en) | 2017-10-13 | 2019-04-18 | Harpoon Therapeutics, Inc. | Trispecific proteins and methods of use |
AU2018387829A1 (en) | 2017-12-22 | 2020-05-07 | Argenx Bvba | Bispecific antigen binding construct |
GB201802487D0 (en) | 2018-02-15 | 2018-04-04 | Argenx Bvba | Cytokine combination therapy |
SG11202011830SA (en) | 2018-06-13 | 2020-12-30 | Novartis Ag | Bcma chimeric antigen receptors and uses thereof |
IL297931B1 (en) | 2018-09-25 | 2024-11-01 | Harpoon Therapeutics Inc | DLL3 binding proteins and methods of use |
CN113811549A (zh) | 2019-02-21 | 2021-12-17 | Xencor股份有限公司 | 非靶向和靶向性il-10 fc融合蛋白 |
JP2022521428A (ja) | 2019-02-25 | 2022-04-07 | ザ・ユニバーシティ・オブ・シカゴ | 抗炎症剤に連結されたecm親和性ペプチドを用いて炎症性状態および自己免疫状態を処置するための方法および組成物 |
CN113677705A (zh) * | 2019-03-04 | 2021-11-19 | 南通壹宸生物医药科技有限公司 | 新型双特异性结合分子及其药物偶联物 |
CN110407943B (zh) * | 2019-04-25 | 2021-03-30 | 华南农业大学 | 一种克百威农药的纳米抗体及其制备方法和应用 |
CN114040926A (zh) * | 2019-05-04 | 2022-02-11 | 印希比股份有限公司 | 结合cd123的多肽及其用途 |
WO2020239945A1 (en) | 2019-05-28 | 2020-12-03 | Vib Vzw | Cancer treatment by targeting plexins in the immune compartment |
AU2020286523A1 (en) | 2019-06-03 | 2022-02-03 | The University Of Chicago | Methods and compositions for treating cancer with cancer-targeted adjuvants |
US20210147525A1 (en) | 2019-10-18 | 2021-05-20 | The Regents Of The University Of California | Methods and compositions for treating pathogenic blood vessel disorders |
CN111825766B (zh) * | 2019-10-31 | 2021-05-11 | 上海洛启生物医药技术有限公司 | 抗il-4r单域抗体及其应用 |
CA3170833A1 (en) | 2020-02-21 | 2021-08-26 | Harpoon Therapeutics, Inc. | Flt3 binding proteins and methods of use |
AU2021232625A1 (en) | 2020-03-05 | 2022-09-29 | Umc Utrecht Holding B.V. | Membrane ubiquitin ligases to target protein degradation |
CA3178265A1 (en) | 2020-06-18 | 2021-12-23 | Umc Utrecht Holding B.V. | Screening method for effective target - e3 ligase combinations |
US20230256111A1 (en) | 2020-06-24 | 2023-08-17 | Sapreme Technologies B.V. | Combination comprising an adc or an aoc comprising a vhh, and a saponin or a ligand-saponin conjugate |
MX2023000031A (es) | 2020-06-24 | 2023-04-19 | Sapreme Tech Bv | Conjugado de un anticuerpo de dominio unico, una saponina y una molecula efectora, composicion farmaceutica que comprende el mismo, uso terapeutico de dicha composicion farmaceutica. |
WO2021259507A1 (en) | 2020-06-24 | 2021-12-30 | Sapreme Technologies B.V. | Conjugate of a single domain antibody, a saponin and an effector molecule, pharmaceutical composition comprising the same, therapeutic use of said pharmaceutical composition |
US20230270872A1 (en) | 2020-06-24 | 2023-08-31 | Sapreme Technologies B.V. | Conjugate of saponin and single-domain antibody, pharmaceutical composition comprising said conjugate, therapeutic use thereof |
US12122839B2 (en) | 2020-08-05 | 2024-10-22 | Synthekine, Inc. | IFNGR binding synthetic cytokines and methods of use |
EP4192502A4 (en) | 2020-08-05 | 2024-10-09 | Synthekine Inc | COMPOSITIONS AND METHODS RELATING TO IL27 RECEPTOR BINDING |
US12018085B2 (en) | 2020-08-05 | 2024-06-25 | Synthekine, Inc. | Interferon-gamma R2 (IFNGR2) binding molecules comprising single-domain antibodies and method of use thereof to treat autoimmune and inflammatory diseases |
EP4200339A2 (en) * | 2020-08-05 | 2023-06-28 | Synthekine, Inc. | Compositions and methods related to receptor pairings |
WO2022032042A1 (en) * | 2020-08-05 | 2022-02-10 | Synthekine, Inc. | Il12 receptor synthetic cytokines and methods of use |
US20230357414A1 (en) * | 2020-08-05 | 2023-11-09 | Synthekine, Inc. | Il12rb2 binding molecules and methods of use |
US12077594B2 (en) | 2020-08-05 | 2024-09-03 | Synthekine, Inc. | IL2RG binding molecules and methods of use |
WO2022031929A1 (en) * | 2020-08-05 | 2022-02-10 | Synthekine, Inc. | Il12rb1-binding molecules and methods of use |
WO2022031940A2 (en) * | 2020-08-05 | 2022-02-10 | Synthekine, Inc. | Il28ra binding molecules and methods of use |
WO2022032023A2 (en) | 2020-08-05 | 2022-02-10 | Synthekine, Inc. | Il23r binding molecules and methods of use |
AU2021321525A1 (en) * | 2020-08-05 | 2023-03-30 | Synthekine, Inc. | IL10 receptor binding molecules and methods of use |
WO2022063957A1 (en) | 2020-09-24 | 2022-03-31 | Vib Vzw | Biomarker for anti-tumor therapy |
WO2022117569A1 (en) * | 2020-12-02 | 2022-06-09 | Oncurious Nv | A ccr8 antagonist antibody in combination with a lymphotoxin beta receptor agonist antibody in therapy against cancer |
WO2023121447A1 (en) | 2021-12-22 | 2023-06-29 | Sapreme Technologies B.V. | Conjugate of a single domain antibody, a saponin and an effector molecule, pharmaceutical composition comprising the same, therapeutic use of said pharmaceutical composition |
GB202210679D0 (en) * | 2022-07-21 | 2022-09-07 | Dualyx Nv | Binding molecules targeting il-12rb2 |
WO2024028794A1 (en) | 2022-08-02 | 2024-02-08 | Temple Therapeutics BV | Methods for treating endometrial and ovarian hyperproliferative disorders |
WO2024036333A2 (en) * | 2022-08-12 | 2024-02-15 | Epibiologics, Inc. | Degradation of egfr using a bispecific binding agent |
WO2024133935A1 (en) | 2022-12-23 | 2024-06-27 | Ablynx Nv | Protein-based conjugation carriers |
US20240368250A1 (en) | 2023-02-17 | 2024-11-07 | Ablynx N.V. | Polypeptides binding to the neonatal fc receptor |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2005249396B2 (en) * | 2004-05-05 | 2011-10-20 | Merrimack Pharmaceuticals, Inc. | Bispecific binding agents for modulating biological activity |
FR2879605B1 (fr) * | 2004-12-16 | 2008-10-17 | Centre Nat Rech Scient Cnrse | Production de formats d'anticorps et applications immunologiques de ces formats |
KR20070114765A (ko) * | 2005-02-23 | 2007-12-04 | 메리맥 파마슈티컬즈, 인크. | 생물학적 활성을 조절하기 위한 이특이성 결합제 |
US20090252681A1 (en) * | 2005-10-11 | 2009-10-08 | Ablynx N.V. | Nanobodies and Polypeptides Against EGFR and IGF-IR |
JP2009511032A (ja) * | 2005-10-11 | 2009-03-19 | アブリンクス エン.ヴェー. | Egfrおよびigf−irに対するナノボディおよびポリペプチド |
KR20080077261A (ko) * | 2005-12-06 | 2008-08-21 | 도만티스 리미티드 | Egfr 및/또는 vegf에 대해 결합 특이성이 있는리간드 및 그의 사용 방법 |
EP1963370A1 (en) * | 2005-12-06 | 2008-09-03 | Domantis Limited | Bispecific ligands with binding specificity to cell surface targets and methods of use therefor |
EP2195342A1 (en) * | 2007-09-07 | 2010-06-16 | Ablynx N.V. | Binding molecules with multiple binding sites, compositions comprising the same and uses thereof |
WO2009068625A2 (en) * | 2007-11-27 | 2009-06-04 | Ablynx N.V. | Amino acid sequences directed against her2 and polypeptides comprising the same for the treatment of cancers and/or tumors |
US10981998B2 (en) * | 2008-10-01 | 2021-04-20 | Amgen Research (Munich) Gmbh | Cross-species-specific single domain bispecific single chain antibody |
WO2010043650A2 (en) * | 2008-10-14 | 2010-04-22 | Ablynx Nv | Amino acid sequences directed against cellular receptors for viruses and bacteria |
EP2621953B1 (en) * | 2010-09-30 | 2017-04-05 | Ablynx N.V. | Biological materials related to c-met |
US20150158934A1 (en) * | 2011-09-09 | 2015-06-11 | Ucl Business Plc | Broadly neutralizing vhh against hiv-1 |
GB2504139B (en) * | 2012-07-20 | 2014-12-31 | Argen X Bv | Antibodies to highly conserved targets produced by the immunisation of Camelidae species |
-
2014
- 2014-09-26 PL PL14777078T patent/PL3049439T3/pl unknown
- 2014-09-26 JP JP2016517433A patent/JP6721503B2/ja active Active
- 2014-09-26 WO PCT/EP2014/070692 patent/WO2015044386A1/en active Application Filing
- 2014-09-26 AU AU2014326674A patent/AU2014326674B2/en active Active
- 2014-09-26 ES ES14777078T patent/ES2779123T3/es active Active
- 2014-09-26 PT PT147770788T patent/PT3049439T/pt unknown
- 2014-09-26 CN CN202210679514.9A patent/CN115160441A/zh active Pending
- 2014-09-26 CN CN201480064344.7A patent/CN105814082A/zh active Pending
- 2014-09-26 EP EP14777078.8A patent/EP3049439B1/en active Active
- 2014-09-26 US US15/024,993 patent/US20160251440A1/en not_active Abandoned
- 2014-09-26 CA CA2925061A patent/CA2925061C/en active Active
-
2021
- 2021-12-02 US US17/540,310 patent/US20220242958A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
WO2015044386A1 (en) | 2015-04-02 |
CA2925061C (en) | 2023-02-14 |
JP2016538242A (ja) | 2016-12-08 |
PT3049439T (pt) | 2020-03-31 |
EP3049439B1 (en) | 2019-12-25 |
AU2014326674A1 (en) | 2016-04-28 |
ES2779123T3 (es) | 2020-08-13 |
US20160251440A1 (en) | 2016-09-01 |
CN115160441A (zh) | 2022-10-11 |
CN105814082A (zh) | 2016-07-27 |
AU2014326674B2 (en) | 2020-03-12 |
US20220242958A1 (en) | 2022-08-04 |
JP6721503B2 (ja) | 2020-07-15 |
EP3049439A1 (en) | 2016-08-03 |
CA2925061A1 (en) | 2015-04-02 |
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