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KR860001800A - 6-Fluoro-1,8-naphthyridine derivatives, 3/2 hydrates thereof and methods for preparing the salts thereof - Google Patents

6-Fluoro-1,8-naphthyridine derivatives, 3/2 hydrates thereof and methods for preparing the salts thereof Download PDF

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Publication number
KR860001800A
KR860001800A KR1019840004636A KR840004636A KR860001800A KR 860001800 A KR860001800 A KR 860001800A KR 1019840004636 A KR1019840004636 A KR 1019840004636A KR 840004636 A KR840004636 A KR 840004636A KR 860001800 A KR860001800 A KR 860001800A
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KR
South Korea
Prior art keywords
fluoro
naphthyridine
salts
preparing
hydrates
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Application number
KR1019840004636A
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Korean (ko)
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KR900001884B1 (en
Inventor
시로오(외 1) 가또오
Original Assignee
후지와라 토미오
다이닛뽕 세이야꾸 가부시끼 가이샤
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Priority to KR1019840004636A priority Critical patent/KR900001884B1/en
Publication of KR860001800A publication Critical patent/KR860001800A/en
Application granted granted Critical
Publication of KR900001884B1 publication Critical patent/KR900001884B1/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

내용 없음No content

Description

6-플루오로-1,8-나프티리딘 유도체, 그의 3/2수화물 및 그 염의 제조방법6-Fluoro-1,8-naphthyridine derivatives, 3/2 hydrates thereof and methods for preparing the salts thereof

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음As this is a public information case, the full text was not included.

Claims (3)

하기식(Ⅰ)을 갖는 6-플루오로-1,8-나프티리딘 유도체, 그의 3/2수화물(sesquihydrate) 및 그 염의 제조방법에 있어서, 하기식(Ⅱ)를 갖는 1,8-나프티리딘-2,3-디카르본산 유도체 또는 그의 산부가염을 가열하여 2위치의 카르보실기를 탈리시키는 것을 특징으로 하는 하기식(Ⅰ)로 표시되는 6-플루오로-1,8-나프티리딘 유도체, 그의 3/2수화물 및 그 염의 제조방법.In the 6-fluoro-1,8-naphthyridine derivative which has following formula (I), the 3/2 hydrate (sesquihydrate), and its manufacturing method, 1,8-naphthyridine which has following formula (II) 6-fluoro-1,8-naphthyridine derivatives represented by the following formula (I) characterized by heating a 2,3-dicarboxylic acid derivative or an acid addition salt thereof to desorb a carbosyl group in a 2-position; / 2 method for preparing a hydrate and salts thereof. 제1항에 있어서, 원료화합물(Ⅱ)을 100℃ 내지 270℃에서 가열하는 것을 특징으로 하는 6-플루오로-1,8-나프티리딘 유도체의 제조방법.The process for producing a 6-fluoro-1,8-naphthyridine derivative according to claim 1, wherein the raw material compound (II) is heated at 100 ° C to 270 ° C. 제1항에 있어서, 목적물이 식(Ⅰ)으로 표시되는 화합물의 3/2수화물인 것을 특징으로 하는 6-플루오로-1,8-나프티리딘 유도체의 제조방법.The method for producing a 6-fluoro-1,8-naphthyridine derivative according to claim 1, wherein the target substance is a 3/2 hydrate of the compound represented by formula (I). ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019840004636A 1984-08-03 1984-08-03 Process for preparation of 6-fluoro-1,8-naphthyridine derivatives, its 3/2 hydrate and salts KR900001884B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019840004636A KR900001884B1 (en) 1984-08-03 1984-08-03 Process for preparation of 6-fluoro-1,8-naphthyridine derivatives, its 3/2 hydrate and salts

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019840004636A KR900001884B1 (en) 1984-08-03 1984-08-03 Process for preparation of 6-fluoro-1,8-naphthyridine derivatives, its 3/2 hydrate and salts

Publications (2)

Publication Number Publication Date
KR860001800A true KR860001800A (en) 1986-03-22
KR900001884B1 KR900001884B1 (en) 1990-03-26

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KR1019840004636A KR900001884B1 (en) 1984-08-03 1984-08-03 Process for preparation of 6-fluoro-1,8-naphthyridine derivatives, its 3/2 hydrate and salts

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Also Published As

Publication number Publication date
KR900001884B1 (en) 1990-03-26

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