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JPS56122309A - Calcitonin pharmaceutical for rectal administration - Google Patents

Calcitonin pharmaceutical for rectal administration

Info

Publication number
JPS56122309A
JPS56122309A JP2519780A JP2519780A JPS56122309A JP S56122309 A JPS56122309 A JP S56122309A JP 2519780 A JP2519780 A JP 2519780A JP 2519780 A JP2519780 A JP 2519780A JP S56122309 A JPS56122309 A JP S56122309A
Authority
JP
Japan
Prior art keywords
calcitonin
pharmaceutical
surfactant
rectal administration
hypercalcemia
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2519780A
Other languages
Japanese (ja)
Other versions
JPS6236498B2 (en
Inventor
Kunio Sekine
Hisao Yamaguchi
Yoshiki Suzuki
Gentaro Yamashita
Yoshinobu Hashimoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teijin Ltd
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd filed Critical Teijin Ltd
Priority to JP2519780A priority Critical patent/JPS56122309A/en
Publication of JPS56122309A publication Critical patent/JPS56122309A/en
Publication of JPS6236498B2 publication Critical patent/JPS6236498B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

PURPOSE: To obtain the titled pharmaceutical, useful for hypercalcemia, particularly senile osteporosis, easily administrable, and prepared by dispersing calcitonin and surfactant in a suppository base uniformly.
CONSTITUTION: Calcitonin and a surfactant, e.g. sodlim glycolate, are dispersed in a suppository base, e.g. cacao butter, in a meat mill, etc. uniformly., and if necessary molded to give a calcitonin pharmaceutical for rectal administration. The surfactant is used in an amount of preferably 0.01W5mg based on 1MRC unit calcitonin. The calcitonin acts on the bone, intestinal tract, and kidney to reduce the calcium ions and inorganic phosphrous in blood, and is useful for hypercalcemia. However, the calcitonin has been administered only by injection. The pharmaceutical is a suppository easily administrable and effectively absorbed by the rectum.
COPYRIGHT: (C)1981,JPO&Japio
JP2519780A 1980-03-03 1980-03-03 Calcitonin pharmaceutical for rectal administration Granted JPS56122309A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2519780A JPS56122309A (en) 1980-03-03 1980-03-03 Calcitonin pharmaceutical for rectal administration

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2519780A JPS56122309A (en) 1980-03-03 1980-03-03 Calcitonin pharmaceutical for rectal administration

Publications (2)

Publication Number Publication Date
JPS56122309A true JPS56122309A (en) 1981-09-25
JPS6236498B2 JPS6236498B2 (en) 1987-08-07

Family

ID=12159222

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2519780A Granted JPS56122309A (en) 1980-03-03 1980-03-03 Calcitonin pharmaceutical for rectal administration

Country Status (1)

Country Link
JP (1) JPS56122309A (en)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5989619A (en) * 1982-10-05 1984-05-23 サンド・アクチエンゲゼルシヤフト Calcitonin composition and use
JPS59130820A (en) * 1982-12-29 1984-07-27 ア−マ−・フア−マシユ−テイカル・カンパニ− Promotion of calcitonin absorption to nose inside with surfactant-containing composition
JPS60161924A (en) * 1984-02-01 1985-08-23 Fujisawa Pharmaceut Co Ltd Composition for lung absorption
JPH02262526A (en) * 1982-10-05 1990-10-25 Sandoz Ag Calcitonine composition and use thereof
US5238917A (en) * 1989-09-11 1993-08-24 Teikoku Seiyaku Kabushiki Kaisha High-absorbable transvaginal preparation containing biologically active polypeptide
US5364632A (en) * 1989-04-05 1994-11-15 Yissum Research Development Company Of The Hebrew University Of Jerusalem Medicinal emulsions
US5393738A (en) * 1986-05-27 1995-02-28 Sandoz, Ltd. Pharmaceutical compositions containing octreotide and excipients for oral or rectal administration
WO1995033474A1 (en) * 1994-06-03 1995-12-14 Tsumura & Co. Medicinal composition
US5824646A (en) * 1988-03-11 1998-10-20 Teikoku Seiyaku Co., Ltd. Intravaginal delivery of biologically active polypeptides

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0235595U (en) * 1988-08-25 1990-03-07

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5989619A (en) * 1982-10-05 1984-05-23 サンド・アクチエンゲゼルシヤフト Calcitonin composition and use
JPH02262526A (en) * 1982-10-05 1990-10-25 Sandoz Ag Calcitonine composition and use thereof
JPH0354647B2 (en) * 1982-10-05 1991-08-20
JPS59130820A (en) * 1982-12-29 1984-07-27 ア−マ−・フア−マシユ−テイカル・カンパニ− Promotion of calcitonin absorption to nose inside with surfactant-containing composition
JPS60161924A (en) * 1984-02-01 1985-08-23 Fujisawa Pharmaceut Co Ltd Composition for lung absorption
US5393738A (en) * 1986-05-27 1995-02-28 Sandoz, Ltd. Pharmaceutical compositions containing octreotide and excipients for oral or rectal administration
US5824646A (en) * 1988-03-11 1998-10-20 Teikoku Seiyaku Co., Ltd. Intravaginal delivery of biologically active polypeptides
US5840685A (en) * 1988-03-11 1998-11-24 Teikoku Seiyaku Co., Ltd. Intravaginal delivery of biologically active polypeptides
US5364632A (en) * 1989-04-05 1994-11-15 Yissum Research Development Company Of The Hebrew University Of Jerusalem Medicinal emulsions
US5238917A (en) * 1989-09-11 1993-08-24 Teikoku Seiyaku Kabushiki Kaisha High-absorbable transvaginal preparation containing biologically active polypeptide
WO1995033474A1 (en) * 1994-06-03 1995-12-14 Tsumura & Co. Medicinal composition

Also Published As

Publication number Publication date
JPS6236498B2 (en) 1987-08-07

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