JPS5441869A - 1-methylsulfinyl-1-methylthio-2-(n-alkylpyrrolyl-2)- ethylene - Google Patents
1-methylsulfinyl-1-methylthio-2-(n-alkylpyrrolyl-2)- ethyleneInfo
- Publication number
- JPS5441869A JPS5441869A JP10155077A JP10155077A JPS5441869A JP S5441869 A JPS5441869 A JP S5441869A JP 10155077 A JP10155077 A JP 10155077A JP 10155077 A JP10155077 A JP 10155077A JP S5441869 A JPS5441869 A JP S5441869A
- Authority
- JP
- Japan
- Prior art keywords
- methylthio
- ethylene
- alkylpyrrolyl
- methylsulfinyl
- methylpyrrolyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pyrrole Compounds (AREA)
Abstract
NEW MATERIAL:1-Methylsulfinyl-1-methylthio-2-(N-alkylpyrrolyl-2-) ethylene of formulaI(R is lower alkyl, preferably methyl).
EXAMPLE: 1-methylsufinyl-1-methylthio-2-(N-methylpyrrolyl-2)ethylene.
USE: Intermediates of tolmetin,[N-methyl-5-(p-toluoyl)pyrrolyl-2], an autiflammatory agent.
PREPARATION: The reaction between an aldehyde of formula II and formaldehyde dimethylmercaptal-s-oxide of formula III is carried out in the presence of a strong base to afford the objective compound of formulaI. The resulting product is reacted with acetic anhydride, treated with an amine and hydrolyzed by an alkali to give (N-methylpyrrolyl-2) acetic acid that is useful as the starting material of tolmetin.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10155077A JPS5441869A (en) | 1977-08-26 | 1977-08-26 | 1-methylsulfinyl-1-methylthio-2-(n-alkylpyrrolyl-2)- ethylene |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10155077A JPS5441869A (en) | 1977-08-26 | 1977-08-26 | 1-methylsulfinyl-1-methylthio-2-(n-alkylpyrrolyl-2)- ethylene |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5441869A true JPS5441869A (en) | 1979-04-03 |
JPS5728700B2 JPS5728700B2 (en) | 1982-06-18 |
Family
ID=14303527
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP10155077A Granted JPS5441869A (en) | 1977-08-26 | 1977-08-26 | 1-methylsulfinyl-1-methylthio-2-(n-alkylpyrrolyl-2)- ethylene |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5441869A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58101461A (en) * | 1981-12-11 | 1983-06-16 | Mitsubishi Electric Corp | Gate turn-off thyristor |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU569612B2 (en) * | 1984-04-16 | 1988-02-11 | Fmc Corporation | Process and apparatus to hydrolyse lactose to glucose and galactose |
-
1977
- 1977-08-26 JP JP10155077A patent/JPS5441869A/en active Granted
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58101461A (en) * | 1981-12-11 | 1983-06-16 | Mitsubishi Electric Corp | Gate turn-off thyristor |
Also Published As
Publication number | Publication date |
---|---|
JPS5728700B2 (en) | 1982-06-18 |
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