JP3951085B2 - Dentifrice composition - Google Patents

Description

【００３８】
【表２】

【００３９】
【表３】

【００４０】
【表４】

【００４１】
表１〜４の結果より、水溶性ポリリン酸塩と炭素数３以下の低級アルコールとカルシウムイオンを放出しない水不溶性研磨剤を配合する歯磨組成物において、粘結剤としてヒドロキシエチルセルロース、又はヒドロキシエチルセルロースとアルギン酸塩とを組み合わせて配合することにより、保存安定性、使用感に優れ、かつ歯牙の清掃力に優れた歯磨組成物が得られることを確認した。
【００４２】
〔実施例１２〕練歯磨（ペースト状）
トリポリリン酸ナトリウム １０．０％
プロピルアルコール ３．０
ヒドロキシエチルセルロース ２．０
アルギン酸ナトリウム １．０
カルボキシビニルポリマー（カルボポール９４０） ０．２
無水ケイ酸 ２０．０
ラウリル硫酸ナトリウム １．５
プロピレングリコール ３．０
ソルビット １５．０
トリクロサン ０．０５
オウバク ０．０５
トラネキサム酸 ０．０５
安息香酸ナトリウム ０．５
香料 １．０
サッカリンナトリウム ０．１
精製水 バランス
計 １００％
【００４４】
〔実施例１３〕練歯磨（ペースト状）
メタリン酸ナトリウム（Ｐ鎖＝４０） １．０％
エチルアルコール ２０．０
ヒドロキシエチルセルロース １．５
カルボキシビニルポリマー（カルボポール９４０） １．０
水酸化アルミニウム ３０．０
酸化アルミニウム ５．０
プロピレングリコール ３．０
ポリエチレングリコール ３．０
ソルビット １５．０
塩化セチルピリジニウム ０．０５
香料 １．０
サッカリンナトリウム ０．１
精製水 バランス
計 １００％
【００４９】
〔実施例１４〕泡状歯磨
ピロリン酸カリウム ０．１％
メタリン酸ナトリウム（Ｐ鎖＝４０） ０．１
ヘキサメタリン酸ナトリウム（環状） ０．１
エチルアルコール ５．０
プロピルアルコール １０．０
ヒドロキシエチルセルロース ０．７
アルギン酸ナトリウム ０．３
無水ケイ酸 １０．０
Ｎ−ラウロイルメチルタウリンナトリウム ５．０
ソルビット ２０．０
キシリトール １０．０
塩化セチルピリジニウム ０．０５
香料 １．０
サッカリンナトリウム ０．１
精製水 バランス
計 １００％[0001]
BACKGROUND OF THE INVENTION
The present invention relates to a dentifrice composition having an excellent tooth cleaning effect, and having improved appearance and property stability over time.
[0002]
[Prior art and problems to be solved by the invention]
Conventionally, various cleaning methods have been studied in order to remove colored substances (stains) such as tobacco dust and tea astringent attached to teeth. In particular, brushing with a dentifrice and toothbrush that contains chemical cleaning ingredients such as chelating agents, polyethylene glycol, and specific fragrance ingredients is simple and efficient in a short time due to the synergistic action of physical cleaning and chemical cleaning. Tooth stains on teeth can be removed.
[0003]
Various proposals have been made as components for chemically removing tooth stains as follows.
U.S. Pat. No. 3,998,433: An oral composition containing a specific organic peroxide.
US Pat. No. 4,183,916: An oral composition using a cationic surfactant and malic acid in combination.
Japanese Examined Patent Publication No. 48-43869: An oral composition containing an ester having an aromatic ring.
JP-A-51-139939: An oral composition containing a chelating agent having a stability coefficient of Fe> Ca.
JP 56-18911 A: A composition for oral cavity using phytic acid and an organic acid in combination.
JP-A-60-4117: An oral composition containing tartronic acid, glyceric acid, hydroxy-n-butyric acid or dihydroxymalonic acid.
JP-A-61-286315: A composition for oral cavity in which carvone, anethole or 3-octanol is used in combination with a solvent extract of a genus plant.
JP 62-151498 A: An oral composition containing 2-octanol.
Japanese Patent Laid-Open No. 62-181212: A composition for oral cavity containing a specific monoterpene.
JP 62-189233 A: An oral composition containing an aliphatic ester having 7 to 11 total carbon atoms.
Among these, water-soluble polyphosphates such as pyrophosphate and tripolyphosphate have been attracting attention for a long time as components that can remove the coloring of teeth without damaging the teeth, and the following proposals have been made conventionally. .
JP, 52-108029, A: A composition for oral cavity which uses polyphosphate and a polyvalent metal cation together.
JP-A-1-250312: An oral composition containing an aldehyde compound having 7 to 9 carbon atoms and a polyphosphate.
JP-A-7-10726: An oral composition containing no citrate, a citrate, a water-soluble polyphosphate, and a nonionic surfactant having an HLB of 7 to 14 in combination.
JP-A-9-12437: A composition for oral cavity that chemically cleans tooth stains using a combination of polyphosphate, orthophosphate and amphoteric surfactant.
Japanese Patent Laid-Open No. 9-12438: A composition for oral cavity that chemically cleans teeth dirt using polyphosphate, orthophosphate and alkyl sulfate in combination.
JP-A-9-175966: A composition for oral cavity that chemically cleans teeth stains using a combination of pyrophosphate and polyphosphate (P ≧ 3).
JP 9-501679 A: A composition for whitening teeth using a sequestering agent (tripolyphosphate) and a reducing agent (vitamin C) in combination.
JP-T 9-507481 A composition for whitening teeth containing 5 to 15% by weight of a water-soluble alkali metal tripolyphosphate.
JP-A-10-182386: A composition for oral cavity that chemically cleans teeth stains using polyphosphate and water-insoluble scrub particles derived from animals and plants.
[0004]
However, in the case of polyphosphate alone and the method proposed above, the stain attached to the tooth surface may not be sufficiently removed in a short time.
[0005]
Accordingly, the present invention provides a dentifrice composition that is excellent in tooth cleaning action, has a high stain removal effect, and has high appearance and stable property over time.
[0006]
Means for Solving the Problem and Embodiment of the Invention
The present inventor has made various studies to achieve the above object, and the stain removal function of the water-soluble polyphosphate has the effect of dissolving, polishing, or decolorizing and removing the stain from the surface layer. Focusing on the fact that the binding between stain and enamel can be weakened by penetrating and permeating into stain to reach the enamel of the tooth surface layer, and as a result of examination, as a result of investigation, abrasive, carbon number 3 The combination of the following lower alcohols, preferably anionic surfactants, promotes stain penetration and permeation of polyphosphate, and from these facts, in order to obtain a dentifrice with a high chemical cleaning effect, A water-soluble polyphosphate, a lower alcohol having 3 or less carbon atoms, and a water-insoluble abrasive that does not release calcium ions are blended, more preferably an anionic surfactant. It was found that it is sufficient to use. However, in a dentifrice that contains a water-soluble polyphosphate, a lower alcohol having 3 or less carbon atoms, and a water-insoluble abrasive that does not release calcium ions at the same time, the general-purpose binder does not thicken and gel, The appearance at the time of manufacture and the long-term storage test may impair the appearance such as rough skin and liquid separation, and a solution to this point has been required.
[0007]
Here, the abrasive is an essential component of a dentifrice for the purpose of whitening cleaning, and an anionic surfactant represented by sodium lauryl sulfate is also a general-purpose component of the dentifrice. On the other hand, ethyl alcohol is generally used as a lower alcohol having 3 or less carbon atoms. For example, JP-A-58-39620 discloses a spruce remover, and JP-A-6-336416 highlights the flavor. As a component for imparting the flavor of the toothpaste, blending into a dentifrice composition has been proposed. Japanese Patent Laid-Open No. 6-336416 discloses that a dentifrice containing ethyl alcohol, polyphosphate, and polyethylene glycol uses sodium carboxymethylcellulose having a specific degree of etherification as a binder, thereby improving the appearance and time. A dentifrice composition excellent in stability has also been proposed.
[0008]
However, when the blending amount of polyphosphate and ethyl alcohol is high, or when polyethylene glycol is not included, even the proposed sodium carboxymethylcellulose is insufficiently thickened and gelled, resulting in better appearance stability. It has been desired to study binders for providing dentifrice compositions.
[0009]
For this reason, the present inventor formulated a water-soluble polyphosphate, a lower alcohol having 3 or less carbon atoms and a water-insoluble abrasive that does not release calcium ions, and more preferably when an anionic surfactant is used in combination. As a result of intensive studies to obtain a dentifrice composition that does not impair appearance such as shape retention, rough skin, and liquid separation even when it is stored at a high temperature for a long period of time as well as excellent cleaning power against colored stains, (A) General Formula (1)
M _{n + 2} P _n O _{3n + 1} (1)
(However, M represents Na or K, and n ≧ 2.)
A linear water-soluble polyphosphate represented by the general formula (2)
(MPO ₃ ) _m (2)
(However, M represents Na or K, and m ≧ 3.)
1 or 2 or more types selected from cyclic water-soluble polyphosphates represented by: (B) 1 or 2 or more types of lower alcohols having 3 or less carbon atoms, and (C) water that does not release calcium ions. blended insoluble abrasive, more preferably in the dentifrice composition in combination with (E) an anionic surfactant, be formulated in combination with a hydroxyethyl cellulose, or hydroxyethyl cellulose and alginate as (D) binder Thus, even after being stored at a high temperature for a long time, it was found that the appearance such as shape retention, rough skin, and liquid separation is not impaired, and the present invention has been made.
[0010]
Hereinafter, the present invention will be described in more detail. The dentifrice composition of the present invention comprises (A) a water-soluble polyphosphate, (B) a lower alcohol having 3 or less carbon atoms, and (C) a water-insoluble abrasive that does not release calcium ions. together, it is obtained by blending a combination of a hydroxyethyl cellulose, or hydroxyethyl cellulose and alginate as (D) binder.
[0011]
As the water-soluble polyphosphate of the component (A) blended in the composition, the general formula (1)
M _{n + 2} P _n O _{3n + 1} (1)
(However, M represents Na or K, and n ≧ 2.)
In other words, sodium pyrophosphate or potassium pyrophosphate having a polymerization degree n = 2, sodium tripolyphosphate or potassium tripolyphosphate having n = 3, sodium tetrapolyphosphate or potassium tetrapolyphosphate having n = 4, Linear polyphosphates such as sodium metaphosphate and potassium metaphosphate, and general formula (2)
(MPO ₃ ) _m (2)
(However, M represents Na or K, and m ≧ 3.)
In other words, cyclic polyphosphorus such as sodium trimetaphosphate and potassium trimetaphosphate having a polymerization degree m = 3, sodium tetrametaphosphate and potassium tetrametaphosphate having m = 4, and sodium hexametaphosphate and potassium hexametaphosphate having m = 6 Acid salts are used. These polyphosphates can be used singly or in combination of two or more, but among these, linear polyphosphates are preferred, and those having a polymerization degree of 2 ≦ n ≦ 50 are particularly preferred. Is preferred.
[0012]
In this case, the amount of the polyphosphate is 0.1 to 15% (% by weight, the same applies hereinafter) in the composition, preferably 0.2 to 10%, particularly preferably 0.3 to 8%. . If it is less than 0.1%, the effect of removing dirt is not sufficiently exhibited, and if it is more than 15%, it may not be uniformly dissolved in the preparation or an unpleasant flavor may be felt.
[0013]
In addition, as the lower alcohol having 3 or less carbon atoms in the component (B) used in combination with the polyphosphate, methyl alcohol, ethyl alcohol, or propyl alcohol is used, and preferably one or two of ethyl alcohol or propyl alcohol The above is preferably used.
[0014]
The blending amount of the lower alcohol is 1 to 30%, desirably 1 to 20% in the composition. If it is less than 1%, the effect of penetrating the polyphosphate into the stain is weak, and the effect of removing dirt is not fully exhibited. If it is more than 30%, the polyphosphate cannot be dissolved and the preparation becomes uneven or uncomfortable. May cause irritation to the mucous membrane.
[0015]
In this invention, in order not to impair the chelate effect of polyphosphate, it is necessary to use an abrasive that does not elute calcium ions as component (C). Examples of such abrasives include anhydrous silicic acid, aluminum silicate, zirconium silicate, insoluble sodium metaphosphate, bentonite, aluminum hydroxide, alumina, titanium oxide, crystalline cellulose, polymethyl methacrylate, and other synthetic resins. In particular, it is desirable to use silicic anhydride. These abrasive | polishing agents can be used 1 type or in combination of 2 or more types, 2-70% can be mix | blended in a dentifrice composition, More preferably, 5-50% can be mix | blended. When the blending amount of the abrasive is less than 2%, the dirt cleaning effect cannot be sufficiently exerted, and when it is more than 70%, the teeth may be shaved or scratched.
[0016]
Further, in the present invention are formulated in combination with (D) as a caking agent ingredients, hydroxyethyl cellulose, or hydroxyethyl cellulose and alginate.
[0017]
Here, as hydroxyalkyl cellulose, hydroxyethyl cellulose and hydroxypropyl cellulose are effectively used. Among these, hydroxyalkyl cellulose having an average addition mole number of ethylene oxide of 1.3 to 2.5, particularly hydroxyethyl cellulose. More preferably, is used. By blending this with 0.01 to 15%, particularly 0.1 to 10% of the whole composition, the stability of the composition is improved satisfactorily. When the average added mole number of these hydroxyalkyl celluloses is less than the above range, the skin may be deteriorated, and when it exceeds the above range, moldability may be deteriorated or spinnability may occur. If the blending amount is less than 0.01%, the effect as a binder cannot be expressed. If the blending amount is more than 15%, it does not dissolve in the composition and the preparation becomes non-uniform, or the preparation becomes hard and difficult to come out of the tube. There is a case.
[0018]
Examples of the alginate include sodium alginate and potassium alginate having a cation that does not elute calcium, and sodium alginate is particularly preferable. The blending amount of these alginate improves the stability of the composition satisfactorily by blending 0.01 to 15%, particularly 0.1 to 10% of the whole composition. When the blending amount of alginate is less than 0.01%, the effect as a binder cannot be expressed, and when it exceeds 15%, it does not dissolve in the composition, the formulation becomes non-uniform, the formulation becomes hard and the tube becomes hard. It may be difficult to get out.
[0020]
In addition, when silicic anhydride is used for the abrasive, hydroxyethylcellulose alone or a combination of hydroxyethylcellulose and sodium alginate as a binder is not spinnable, has good moldability, good skin, unpleasant taste and stickiness. It is more preferable because there is no sense of incongruity such as stickiness. The mixing ratio of hydroxyethyl cellulose and sodium alginate is preferably 10: 0 to 1:10, more preferably 9: 1 to 2: 8. When the ratio of hydroxyethyl cellulose to sodium alginate is less than 1:10, the paste becomes brittle and the feeling of use decreases, or in a composition having a high concentration of polyphosphate or lower alcohol, In some cases, the quality of the appearance such as separation may be deteriorated.
[0021]
In the dentifrice composition of the present invention, it is more desirable to use an anionic surfactant in combination as the component (E) in order to increase the stain penetration of the polyphosphate and enhance the cleaning effect. In this case, examples of the anionic surfactant include sodium alkyl sulfates such as sodium lauryl sulfate, sodium myristyl sulfate and sodium cetyl sulfate, sodium N-acyl glutamate such as sodium N-lauroyl glutamate, sodium N-palmitoyl glutamate, and N-lauroyl sarcosine. Sodium, sodium N-acyl sarcosine such as sodium N-myristoyl sarcosine, sodium N-lauroylmethyl taurine, sodium N-methyl-N-acyl taurine such as sodium N-myristoyl methyl taurine, sodium N-methyl-N-acylalanine, Sodium lauryl benzene sulfonate, hydrogenated coconut fatty acid monoglyceride sodium monosulfate, sodium lauryl sulfoacetate, α-o Sodium fins sulfonate, lauryl POE sodium sulfate, sodium lauryl POE acetate, sodium lauryl POE phosphate, stearyl POE sodium phosphate and the like are used.
[0022]
In this case, sodium alkyl sulfate, sodium N-acyl glutamate, sodium N-acyl sarcosine, sodium N-methyl-N-acyl taurine and sodium N-methyl-N-acylalanine are preferably used.
[0023]
The compounding amount of the anionic surfactant is 0.3 to 10%, preferably 0.5 to 5% in the composition. If it is less than 0.3%, the effect of allowing the polyphosphate to penetrate into the stain is weak, and the effect of removing dirt is not sufficiently exhibited. If it is more than 10%, an unpleasant feeling of use or irritation to the mucous membrane may be felt.
[0024]
Furthermore, in addition to the above-described components, the dentifrice composition of the present invention is further blended with appropriate components according to the purpose, the type of the composition, etc., and in the form of paste, gel, liquid, foam, etc. Can be in dosage form.
[0025]
For example, the binder, for the purpose of improving the usability in the mouth, may be above hydroxyethyl cellulose, in addition to the alginate in combination with other gelling agents. In this case, as the gelling agent, cellulose derivatives such as sodium carboxymethylcellulose and methylcellulose, gums such as carrageenan, xanthan gum, tragacanth gum, karaya gum, gum arabic, gellan gum, native gellan gum, polyvinyl alcohol, polyvinylpyrrolidone, polyethylene oxide, etc. One type or two or more types of inorganic binders such as a binder, silica gel, aluminum silica gel, bee gum, and laponite can be blended.
[0026]
Furthermore, in the production of paste-like, liquid, foam-like dentifrice compositions, sorbitol, glycerin, ethylene glycol, propylene glycol, 1,3-butylene glycol, polyethylene glycol, polypropylene glycol, xylitol, maltitol, 1 type (s) or 2 or more types, such as lactitol, can be mix | blended (in the case of a toothpaste, 10-70% normally).
[0027]
Moreover, as surfactant, 1 type (s) or 2 or more types of nonionic surfactant and zwitterionic surfactant can also be used together other than anionic surfactant. In this case, nonionic surfactants include glycerin fatty acid esters such as monoglyceryl stearate and decaglyceryl laurate, sugar fatty acid esters such as sucrose fatty acid ester, maltose fatty acid ester, lactose fatty acid ester, maltitol fatty acid ester, and lactitol fatty acid. Sugar alcohol fatty acid esters such as esters, polyoxyethylene sorbitan monolaurate, polyoxyethylene sorbitan fatty acid esters such as polyoxyethylene sorbitan monostearate, polyoxyethylene fatty acid esters such as polyoxyethylene hydrogenated castor oil, myristic acid mono or Fatty acid ethanolamides such as diethanolamide, sorbitan fatty acid esters, polyoxyethylene higher alcohol ethers, polyoxyethylene Polyoxypropylene copolymer, polyoxyethylene polyoxypropylene fatty acid ester or the like is used.
[0028]
Zwitterionic surfactants include alkyldimethylaminoacetic acid betaines such as lauryldimethylaminoacetic acid betaine, N-alkyldiaminoethylglycine such as N-lauryldiaminoethylglycine, N-myristyldiaminoethylglycine, and N-alkyl-N-carboxyl. Methyl ammonium betaine, 2-alkyl-1-hydroxyethyl imidazoline betaine sodium and the like are used.
[0029]
Furthermore, in the present invention, as an active ingredient, an enzyme such as dextranase, mutanase, lysozyme, amylase, protease, lytic enzyme, superoxide dismutanase, or the like, an alkali metal monohydrate such as sodium monofluorophosphate or potassium monofluorophosphate. Fluorine compounds such as fluorophosphate and sodium fluoride, polyethylene glycol, polyvinylpyrrolidone, allantoin, dihydrocholestanol, glycyrrhizic acids, glycyrrhetinic acid, ε-aminocaproic acid, tranexamic acid, bisabolol, isopropylmethylphenol, sodium chloride, triclosan, chlorhexidine Salts, cetylpyridinium chloride, benzethonium chloride, benzalkonium chloride, ascorbic acid and its salts, tocopherol, Ugon, cork tree bark, rosemary, clove, may be incorporated one or more kinds of active ingredients of the herbal extract or the like, such as time.
[0030]
The dentifrice composition of the present invention includes fragrances such as menthol, anethole, carvone, peppermint oil, spearmint oil, preservatives such as benzoic acid and its sodium salt, parabens, red No. 3, red No. 104, yellow No. 4, Blue No. 1, Green No. 3, pigments or colorants such as titanium mica and petals, sweeteners such as sodium saccharin, stevioside, glycyrrhizin, aspartame, and the like can be blended.
[0031]
The pH of the dentifrice composition of the present invention is not particularly limited as long as it is in a range that does not cause safety problems in the oral cavity and the human body, but preferably pH 5.5 to 9 is preferable, and as a pH adjuster , Hydrochloric acid, sulfuric acid, nitric acid, citric acid, phosphoric acid, sodium hydroxide, potassium hydroxide, sodium carbonate, sodium citrate, sodium hydrogen citrate, sodium phosphate, sodium hydrogen phosphate and the like can be blended.
[0032]
【The invention's effect】
The dentifrice composition of the present invention is excellent in cleaning power of teeth, and is excellent in appearance and property stability over time.
[0033]
【Example】
EXAMPLES Hereinafter, although an Example and a comparative example are shown and this invention is demonstrated concretely, this invention is not restrict | limited to the following Example. In addition, all% in each example is weight%.
[0034]
A dentifrice composition having the composition shown in Tables 1 to 4 was prepared by a conventional method, filled in a tube, bottle, or pump container and stored in a thermostatic bath at 50 ° C. for 1 month, and then the appearance of the dentifrice in the container , Easy removal of dentifrice from the container, moldability of the dentifrice from the container, liquid separation, rough skin, stringiness, feeling of use in the mouth (unpleasant / uncomfortable feeling), and cleaning power against dirt on the teeth, respectively Sensory evaluation was performed based on the following criteria. The results are also shown in Tables 1-4.
Appearance (Evaluation of color and uniformity: observed in a container)
◯: There is no layer separation due to discoloration and sedimentation of the abrasive, and the state is uniform.
Δ: Slight discoloration or layer separation occurs.
X: Remarkable discoloration or polishing agent separated and settled, resulting in layer separation.
Ease of extrusion from the container (when pushing out from a tube, bottle, or pump container)
○: Can be easily extruded with normal force.
Δ: Slightly difficult to extrude and requires force.
×: Formability that is very difficult to remove from the container (when extruded from a tube, bottle, or pump container)
○: Moderate shape easy to put on a toothbrush.
Δ: Slightly difficult to place on toothbrush.
X: It is difficult to put on a toothbrush.
Liquid separation (when pushed out of tube, bottle, pump container)
○: There is no exudation of liquid.
Δ: Slight ooze out
X: Exudation of liquid is large.
Rough skin (when pushed out of tube, bottle, pump container)
○: Good skin is maintained.
Δ: Somewhat rough skin.
X: Skin roughness is remarkable.
Spinnability (when extruded from a tube, bottle or pump container)
◯: There is no stringing and the kneading is good.
Δ: There is a little stringing.
X: There is stringing and poor kneading.
Unpleasant taste / uncomfortable feeling ○: No unpleasant taste or unpleasant use feeling such as stickiness / stickiness.
Δ: Slight unpleasant taste or stickiness / stickiness.
X: Unpleasant taste or stickiness / stickiness is strong.
[0035]
Tooth cleaning power (tobacco spider model stain removal power)
10 pieces of smoke (manufactured by JT) was sprayed on white hydroxyapatite chips (diameter 7 mm × height 3 mm) which had been immersed in 30% phosphoric acid for 10 minutes, washed and dried, and heated at 150 ° C. for 3 hours.
After cooling to room temperature, the surface of the hydroxyapatite chip was lightly brushed in running water to remove the coloring matter with weak adhesion, and then air-dried again to obtain a sample chip.
After putting 1g of the preparation on a toothbrush and brushing the surface of the sample chip with 200 times the surface of the sample chip, the preparation adhered to the surface was gently washed away with running water, and the surface of the sample chip remaining on the surface of the sample chip was wiped off. Based on the evaluation.
◯: More than 80% of the initial tobacco adhering has been removed.
(Triangle | delta): Half to less than 80% of the tobacco spear adhering to the initial stage is removed.
X: More than half of the cigarette scum adhering to the initial stage remains.
[0036]
Comprehensive evaluation Evaluation of 8 items of appearance, ease of extrusion, moldability, liquid separation, rough skin, stringiness, unpleasantness / uncomfortableness, and tooth cleaning power were summarized and evaluated based on the following criteria. (Double-circle): The result of all eight items is marked with a circle (particularly excellent sample).
○: Samples with Δ in 1-2 items out of 8 and the rest with ○.
Δ: A sample in which 3 to 4 items out of 8 items are marked with Δ and the rest are marked with ○.
×: Sample with x in 1 item out of 8 items, or 5 items or more without X
Sample with
[0037]
[Table 1]

[0038]
[Table 2]

[0039]
[Table 3]

[0040]
[Table 4]

[0041]
From the results of Tables 1-4, in the dentifrice compositions incorporating water-soluble polyphosphoric acid salt and having 3 or less water-insoluble polishing agents which do not emit lower alcohol and calcium ions atoms, hydroxyethyl cellulose, or hydroxyethyl cellulose as a binder It was confirmed that a dentifrice composition excellent in storage stability and feeling of use and excellent in cleaning power of teeth was obtained by blending and alginate in combination .
[0042]
[Example 12 ] Toothpaste (paste)
Sodium tripolyphosphate 10.0%
Propyl alcohol 3.0
Hydroxyethyl cellulose 2.0
Sodium alginate 1.0
Carboxyvinyl polymer (Carbopol 940) 0.2
Silicic anhydride 20.0
Sodium lauryl sulfate 1.5
Propylene glycol 3.0
Sorbit 15.0
Triclosan 0.05
Aube 0.05
Tranexamic acid 0.05
Sodium benzoate 0.5
Fragrance 1.0
Saccharin sodium 0.1
Purified water balance
Total 100%
[0044]
[Example 13 ] Toothpaste (paste)
Sodium metaphosphate (P chain = 40) 1.0%
Ethyl alcohol 20.0
Hydroxyethyl cellulose 1.5
Carboxyvinyl polymer (Carbopol 940) 1.0
Aluminum hydroxide 30.0
Aluminum oxide 5.0
Propylene glycol 3.0
Polyethylene glycol 3.0
Sorbit 15.0
Cetylpyridinium chloride 0.05
Fragrance 1.0
Saccharin sodium 0.1
Purified water balance
Total 100%
[0049]
[Example 14 ] Foam toothpaste potassium pyrophosphate 0.1%
Sodium metaphosphate (P chain = 40) 0.1
Sodium hexametaphosphate (cyclic) 0.1
Ethyl alcohol 5.0
Propyl alcohol 10.0
Hydroxyethyl cellulose 0.7
Sodium alginate 0.3
Silica anhydride 10.0
N-lauroylmethyl taurine sodium 5.0
Sorbit 20.0
Xylitol 10.0
Cetylpyridinium chloride 0.05
Fragrance 1.0
Saccharin sodium 0.1
Purified water balance
Total 100%

Claims (3)

General formula (1)
M _{n + 2} P _n O _{3n + 1} (1)
(However, M represents Na or K, and n ≧ 2.)
A linear water-soluble polyphosphate represented by the general formula (2)
(MPO ₃ ) _m (2)
(However, M represents Na or K, and m ≧ 3.)
In the one or more selected from water-soluble polyphosphates annular represented, the dentifrice composition in combination with a lower alcohol having 3 or less carbon atoms, a water-insoluble polishing agent which does not release calcium ions, caking dentifrice composition characterized in that blended by combining hydroxyethyl cellulose, or hydroxyethyl cellulose and the alginate as agent.   The dentifrice composition according to claim 1, wherein the water-insoluble abrasive that does not release calcium ions is silicic anhydride.   The dentifrice composition of Claim 1 or 2 which uses an anionic surfactant together.