JP2020002111A - Cleaning set and use thereof - Google Patents

Abstract

To provide means for cleaning dentures and the like in a short time, by using a solid cleaning composition containing an oxygen bleaching agent.SOLUTION: A cleaning set has a solid cleaning composition containing an oxygen bleaching agent and an ultrasonic cleaner.SELECTED DRAWING: None

Description

  The present invention relates to a cleaning set and its use.

  It is important from the viewpoint of oral hygiene and the like to clean oral interior accessories such as dentures, mouthpieces and retainers. For example, cleaning of dentures and the like using a solid cleaning agent containing an oxygen-based bleaching agent is generally performed (Patent Document 1).

  However, in cleaning dentures and the like using a solid detergent containing an oxygen bleaching agent, it is necessary to immerse the dentures and the like overnight, and it takes a long time to sufficiently obtain the effect. On the other hand, in dental clinics and the like, dentures and the like are cleaned by, for example, high-power ultrasonic cleaners, but high-power ultrasonic cleaners used in dental clinics and the like are cleaned by specialized equipment. For this reason, it is difficult to perform cleaning as in a dental clinic or the like in ordinary households.

Japanese Patent No. 5561987

  Therefore, an object of the present invention is to provide a means for cleaning a denture or the like in a short time by using a solid cleaning composition containing an oxygen bleaching agent.

Means for Solving the Problems The present inventors have conducted intensive studies in view of the above problems, and found that a denture or the like can be cleaned in a short time by combining a solid cleaning composition containing an oxygen-based bleach and an ultrasonic cleaner. . The present invention has been completed as a result of further studies based on the findings, and is as follows.
Item 1. A cleaning set comprising a solid cleaning composition containing an oxygen bleach and an ultrasonic cleaner.
Item 2. The cleaning set according to claim 1, wherein the output of the ultrasonic cleaner is 3 to 35W.
Item 3. Item 3. The cleaning set according to item 1 or 2, wherein the solution obtained by dissolving 2.65 g of the solid cleaning composition in 150 mL of water at 25 ° C. has a pH of less than 7.5.
Item 4. The washing set according to any one of Items 1 to 3, wherein the oxygen-based bleach is at least one selected from the group consisting of hydrogen persulfate, perborate, percarbonate and persulfate.
Item 5. Item 5. The cleaning set according to any one of Items 1 to 4, which is used for cleaning oral cavity interior appliances.
Item 6. A cleaning method comprising combining a solid cleaning composition containing an oxygen bleach and an ultrasonic cleaner.

  According to the cleaning set and cleaning method of the present invention, by combining a solid cleaning composition containing an oxygen-based bleach and an ultrasonic cleaner, a denture or the like can be used in a short time while using the solid cleaning composition. Can be washed.

FIG. 1 is an example of a model diagram of the appearance of an ultrasonic cleaner.

The present invention provides a cleaning set comprising a solid cleaning composition comprising an oxygen-based bleach and an ultrasonic cleaner.
Solid cleaning composition containing oxygen bleach The oxygen bleach used in the present invention is not limited, and may be any conventionally known oxygen bleach. As the oxygen-based bleaching agent, conventionally, an oxygen-based bleaching agent which can be used for cleaning oral cavity interior devices such as dentures is preferably exemplified. Examples of the oxygen bleach include hydrogen persulfate, perborate, percarbonate, persulfate and the like. These may be used alone or in combination of two or more.

  Examples of the hydrogen persulfate include alkali metal salts of hydrogen persulfate such as sodium hydrogen persulfate, potassium hydrogen persulfate, and lithium hydrogen persulfate; barium hydrogen persulfate; and ammonium hydrogen persulfate. The salt may be a hydrate. Preferred examples of the hydrogen persulfate include an alkali metal salt of hydrogen persulfate. The hydrogen persulfate may be a hydrogen sulfate or a double salt with a sulfate, and examples thereof include potassium hydrogen persulfate, potassium hydrogen sulfate, and a double salt of potassium sulfate. For example, as commercial products of potassium hydrogen persulfate, potassium hydrogen sulfate, and a double salt of potassium sulfate, oxone (Oxone, LANXESS) is exemplified. These may be used alone or in combination of two or more.

  Examples of the perborate include alkali metal salts of perboric acid such as sodium perborate and potassium perborate, and ammonium perborate, and the perborate may be a hydrate. . As the perborate, an alkali metal salt of perborate is preferably exemplified. These may be used alone or in combination of two or more.

  Examples of the percarbonate include alkali metal salts of percarbonate such as sodium percarbonate and potassium percarbonate, and ammonium percarbonate. The percarbonate may be a hydrate. Preferred examples of the percarbonate include alkali metal salts of percarbonate, and more preferred examples include sodium percarbonate. These may be used alone or in combination of two or more.

  Examples of the persulfate include alkali metal salts of persulfuric acid such as sodium persulfate and potassium persulfate, and ammonium persulfate. The persulfate may be a hydrate. As the persulfate, an alkali metal salt of persulfuric acid is preferably exemplified. These may be used alone or in combination of two or more.

  The content of the oxygen-based bleaching agent in the solid cleaning composition containing the oxygen-based bleaching agent is not limited, but is preferably 3 to 80% by mass, and more preferably 5 to 50% by mass in the composition. .

  In the solid cleaning composition, if necessary, a foaming agent, a chelating agent, a surfactant, a coloring agent, a bactericide, a fragrance, a rust inhibitor, a tartar inhibitor, a foam stabilizer, a binder, a lubricant And other components such as excipients, disintegrants, deodorants, preservatives, pH adjusters, oily components, bleach activators, enzymes and the like. Among these other components, components that can be used conventionally for cleaning oral cavity accessories such as dentures are preferably exemplified. Other components may be used alone or in combination of two or more, and the content thereof may be appropriately set according to the purpose and the like.

  Non-limiting examples of other optional components are set forth below.

  When the solid cleaning composition contains a foaming agent, any known foaming agent may be used. Conventionally, a foaming agent that can be used for cleaning oral appliances such as dentures is preferably exemplified. Refers to those capable of generating carbon dioxide in the presence of water. Preferred examples of the foaming agent include a combination of at least one of carbonate, bicarbonate, and a double salt thereof with an acid.

  The carbonate is not limited as long as it is a conventionally known carbonate. Examples thereof include alkali metal salts of carbonic acid such as sodium carbonate and potassium carbonate, and preferably, sodium carbonate and the like. The carbonate may be an anhydride or a hydrate, and is preferably an anhydride. These may be used alone or in combination of two or more.

  The hydrogencarbonate is not particularly limited as long as it is a conventionally known hydrogencarbonate, and examples thereof include alkali metal salts of hydrogencarbonate such as sodium hydrogencarbonate and potassium hydrogencarbonate, and preferably sodium hydrogencarbonate and the like. . These may be used alone or in combination of two or more.

  The double salt of a carbonate and a hydrogen carbonate is not limited as long as it is a conventionally known double salt, and examples thereof include sodium sesquicarbonate, which is a double salt of sodium hydrogen carbonate and sodium carbonate. These may be used alone or in combination of two or more.

  The acid is not particularly limited as long as it is a conventionally known acid.For example, organic acids such as citric acid, malic acid, tartaric acid, fumaric acid, maleic acid, gluconic acid, succinic acid, salicylic acid, adipic acid, and oxalic acid; Acids, inorganic acids such as sulfamic acid, and salts thereof such as alkali metal salts and alkaline earth metal salts such as sodium salt and potassium salt thereof. More preferably, the acid is citric acid, malic acid, or a salt thereof. These may be used alone or in combination of two or more.

  When the solid cleaning composition contains a blowing agent, the content of at least one of carbonates, bicarbonates and double salts thereof and the acid content is at least one of carbonates, bicarbonates and double salts thereof. There is no limitation as long as the species and the acid can react with each other in water to generate carbon dioxide. For example, in the solid cleaning composition, at least one of carbonate, bicarbonate, and a double salt thereof is mixed with an acid. Is preferably 8 to 80% by mass, more preferably 10 to 60% by mass in the composition as a total amount of these.

  When the composition for solid washing contains a foaming agent, the content of at least one of carbonates, bicarbonates and double salts thereof and an acid is not limited as described above. In the composition, the acid is preferably 15 to 17000 parts by mass, more preferably 15 to 7500 parts by mass, based on 100 parts by mass of the total amount of at least one of carbonate, bicarbonate and double salts thereof. Is done.

  When the solid cleaning composition contains a chelating agent, any known chelating agent may be used, and a chelating agent which can be conventionally used for cleaning oral cavity appliances such as dentures is preferably exemplified. Examples of the chelating agent include ethylenediaminetetraacetic acid and / or a salt thereof, polyphosphoric acid and / or a salt thereof (for example, tetrasodium pyrophosphate, sodium dihydrogen pyrophosphate, and the like). These may be used alone or in combination of two or more.

  When the solid cleaning composition contains a chelating agent, the content of the chelating agent is not limited. For example, the content of the chelating agent in the composition is preferably 0.1 to 15% by mass. And more preferably 0.5 to 10% by mass.

  When the solid cleaning composition contains a surfactant, for example, as an example of the surfactant, conventionally, cationic, anionic, nonionic and amphoteric surfactants that can be used for cleaning oral cavity interior devices such as dentures A wide variety of agents can be used regardless of the type of agent.

  Examples of the cationic surfactant include quaternary ammonium salts such as alkyl (C6-C20) trimethylammonium salt, dialkyl (C6-C20) dimethylammonium salt, and alkyl (C6-C20) dimethylbenzylammonium salt; C6 to C20) amine salts, alkyl (C6 to C20) amine ethylene oxide adducts, and alkylpyridinium salts. These may be used alone or in combination of two or more.

  Examples of the anionic surfactant include a linear or branched alkylbenzene sulfonate having an alkyl group having an average of 8 to 16 carbon atoms, an olefin sulfonate having an average of 8 to 20 carbon atoms in one molecule, and an average. Linear or branched alkyl sulfoacetate having an alkyl group having 8 to 20 carbon atoms, alkyl sulfate having an alkyl group having an average of 8 to 20 carbon atoms, alkane sulfone having an average of 8 to 20 carbon atoms in one molecule Acid salts and the like. Although not limited thereto, examples of the alkyl group include a lauryl group and a myristyl group. As the anionic surfactant, preferably, a linear or branched alkylbenzene sulfonate having an alkyl group having an average of 8 to 16 carbon atoms, an olefin sulfonate having an average of 8 to 20 carbon atoms in one molecule, an average carbon atom Examples thereof include a straight-chain or branched-chain alkyl sulfoacetate having an alkyl group of several 8 to 20, an alkyl sulfate having an alkyl group having an average of 8 to 20 carbon atoms, and more preferably an alkyl group having 10 to 18 carbon atoms. Straight-chain alkylbenzene sulfonate, olefin sulfonate having 10 to 18 carbon atoms in one molecule, straight-chain alkyl sulfoacetate having 10 to 18 carbon atoms, alkyl group having 10 to 18 carbon atoms And the like. These may be used alone or in combination of two or more.

  Examples of the nonionic surfactant include higher alcohol ethylene oxide adduct, higher alcohol propylene oxide adduct, alkylphenol ethylene oxide adduct, alkylphenol propylene oxide adduct, fatty acid ethylene oxide adduct, fatty acid propylene oxide adduct, and Polyhydric alcohol fatty acid ester Ethylene oxide adduct, higher alkylamine ethylene oxide adduct, fatty acid amide ethylene oxide adduct, ethylene oxide adduct of fats and oils, polyethylene glycol type surfactant such as polypropylene glycol ethylene oxide adduct, and fatty acid of glycerol Esters, fatty acid esters of pentaerythritol, fatty acid esters of sorbitol and sorbitan, fatty acids of sucrose Ester, polyhydric alcohol type surfactants such as fatty acid amides of alkyl ethers and alkanolamines such as polyhydric alcohols. These may be used alone or in combination of two or more.

  Examples of the amphoteric surfactant include an amino acid surfactant such as an alkylaminopropionate having an alkyl group having an average of 10 to 16 carbon atoms (eg, sodium laurylaminopropionate), and an alkyl group having an average of 10 to 16 carbon atoms. And betaine-type surfactants such as alkyl dimethyl betaine (lauryl dimethyl betaine, stearyl dimethyl betaine, etc.) and lauryl hydroxyethyl betaine. These may be used alone or in combination of two or more.

  In these surfactants, examples of the salt include acid addition salts such as alkali metal salts such as sodium and potassium, alkaline earth metal salts such as magnesium and calcium, ammonium salts, amine salts, and hydrochlorides. And preferably a sodium salt. These may be used alone or in combination of two or more.

  Among these surfactants, anionic surfactants and nonionic surfactants are preferable, and anionic surfactants are more preferable from the viewpoint that a good cleaning effect can be obtained.

  These surfactants may be used alone or in combination of two or more.

  When the solid cleaning composition contains a surfactant, the content of the surfactant is not limited. For example, in the composition, the content of the surfactant is preferably 0.1 to 5% by mass. And more preferably 0.5 to 4% by mass.

  The solid cleaning composition containing the oxygen bleach of the present invention is not limited as long as it contains the oxygen bleach, but preferably contains the oxygen bleach and the foaming agent. When the solid cleaning composition of the present invention contains an oxygen-based bleaching agent and a foaming agent, the solid cleaning composition can be preferably used as a so-called foaming cleaning composition.

  In this respect, the solid cleaning composition containing the oxygen bleach of the present invention preferably contains a surfactant or the like together with the oxygen bleach, or together with the oxygen bleach and the foaming agent. Good.

  The solid cleaning composition of the present invention is not limited as long as it is solid, and examples thereof include solid forms such as tablets, granules, granules, powders, and powders. The size and shape of the solid cleaning composition are not limited and may be set as appropriate.

  The solid cleaning composition of the present invention is obtained by mixing an oxygen-based bleaching agent and other components as necessary, granulating and compressing as necessary according to a known procedure, and forming a desired form, size, It is manufactured by formulating into a shape.

  Although not limiting the present invention, for example, when the solid cleaning composition of the present invention is a tablet, the mass per tablet may be appropriately set according to the amount of the composition used in one washing and the like. Good, but for example, about 1 to 20 g, preferably 1 to 10 g.

  Although the present invention is not limited thereto, for example, when the solid cleaning composition of the present invention is a tablet, the size per tablet may be appropriately set according to the amount of the composition used in one washing and the like. It is good, for example, a diameter of 10 to 50 mm, preferably 10 to 30 mm, and a thickness of 1 to 20 mm, preferably 1 to 10 mm.

  The object to be cleaned of the solid cleaning composition of the present invention is not limited as long as it is intended for the purpose of cleaning, and preferably, the object is an oral cavity interior device such as a denture, a mouthpiece, and a retainer. The denture may be a complete denture or a partial denture.

  In the present invention, the washing of the control object is carried out in a state in which water containing the solid washing composition of the present invention is brought into contact with the object. There is no limitation as long as the water containing the solid cleaning composition of the present invention comes into contact with the object, but from the viewpoint of effectively cleaning the object, the entire object is immersed in the water containing the composition of the present invention. It is preferable to make contact so that The contact may be carried out, for example, by charging the solid cleaning composition of the present invention into water and then charging the object, charging the solid cleaning composition of the present invention with water, and then subjecting the solid cleaning composition to water. It may be carried out by putting in an object, or by putting the solid cleaning composition of the present invention into water containing an object.

  Although not limited thereto, for example, when the solid cleaning composition of the present invention is a foaming composition, more preferably, the object is dissolved in water by the solid cleaning composition of the present invention. Performing the above-mentioned cleaning so as to come into contact with bubbles released at the time of cleaning is exemplified.

  In the present invention, it is essential that the washing of the control is performed at least under ultrasonic treatment in a state where the object containing the solid cleaning composition of the present invention is brought into contact with water. That is, it may be carried out by contacting the object with the water containing the solid cleaning composition of the present invention as described above, and immediately subjecting the object to ultrasonic treatment. It may be carried out by contacting water containing the cleaning composition with the object, leaving it as it is for a certain period of time, and then subjecting it to ultrasonic treatment.The water containing the solid cleaning composition of the present invention and the object may be used. The object may be brought into contact with the object, and then subjected to ultrasonic treatment, and may be left for a certain period of time after the ultrasonic treatment.

  The time for performing the ultrasonic treatment is not limited, but is, for example, 1 minute to 30 minutes, preferably 3 minutes to 15 minutes, and the shape and size of the solid cleaning composition of the present invention, contamination of an object, and the like. May be appropriately set depending on the degree of The frequency of use of the solid cleaning composition of the present invention is not similarly limited, and may be set as appropriate.

  The water used is not limited, and examples thereof include tap water, purified water, deionized water, and physiological saline. Although the temperature of the water used is not limited, a range of 5 to 50 ° C. is preferably exemplified from the viewpoint of more effectively cleaning the object. Further, in the cleaning of the object, the amount of the solid cleaning composition of the present invention and water used is not limited, and may be appropriately set according to the degree of contamination of the object, and is not limited as long as the effects of the present invention are obtained. However, it is exemplified that 1 to 20 g, preferably 1 to 10 g of the solid cleaning composition of the present invention is used for about 70 to 200 mL of water.

  After the solid cleaning composition of the present invention is poured into water, the pH of the solution when the solid cleaning composition is no longer recognized as a solid in water is not limited as long as the effects of the present invention can be obtained. The pH of the solution is, for example, 12 or less, more preferably less than 7.5, and even more preferably 3 to less than 7.5. Here, the pH means the pH of a solution obtained by dissolving 2.65 g of the solid cleaning composition of the present invention in 150 mL of water (purified water) at 25 ° C., and the pH is a pH meter (manufactured by Horiba, Model No. F). -53).

Ultrasonic cleaning device The ultrasonic cleaning device includes a cleaning layer in which at least the solid cleaning composition of the present invention, water, and the object to be washed are put, and can wash the object by ultrasonic waves. Known ultrasonic cleaners can be used. Although not limiting the present invention, FIG. 1 is illustrated as a model diagram of the appearance of an ultrasonic cleaner.

  The size and shape of the ultrasonic cleaner and the cleaning layer are not limited as long as the object to be cleaned can be cleaned. For example, when the object is a denture, the cleaning layer can accommodate and clean dentures such as full dentures and partial dentures. Any size and shape may be used. It is preferable that the ultrasonic cleaner is compact from the viewpoints of space saving and easy handling.

  Although not limited, the volume of the washing layer is preferably 100 to 600 mL, more preferably 120 to 300 mL. Examples of the shape of the cleaning layer include a circular shape having a diameter or a long side of 12 cm or less, an elliptical shape, a semi-circular shape, and a square shape having a side of 10 cm or less, and an arbitrary shape having a size corresponding thereto. These lower limits are not limited as long as at least the solid cleaning composition of the present invention, water and the object to be cleaned can be charged, and the object to be cleaned can be cleaned by ultrasonic waves.

  The size and shape of the ultrasonic cleaning device may be appropriately set according to the size and shape of the cleaning layer. For example, from the viewpoint of saving space and the like, the size of the ultrasonic cleaning device main body is exemplified by a size that can be substantially accommodated in a cube having a width of 108 cm, a depth of 108 cm, and a height of 67 cm.

  The weight of the ultrasonic cleaner is not limited as long as it can be easily carried. The weight is, for example, 250 to 600 g, preferably 300 to 500 g.

  The frequency in the ultrasonic cleaning is, for example, 15 to 80 kHz, and preferably 30 to 50 kHz. The output is, for example, 3 to 35 W, and preferably 10 to 20 W.

  The cleaning layer may be provided with a mark (for example, a water level line) or the like as a guide for filling water as needed. For example, usually, the mark is provided so as to be visible from the inside of the cleaning layer. Further, at least a part of the cleaning layer may be provided with a discharge port (for example, a portion which is sharp at the upper edge of the cleaning layer) for facilitating discharge of the solution in the cleaning layer. Further, the ultrasonic cleaning device may use a cleaning tray that can be accommodated in the cleaning layer. The cleaning tray may have a mark as a guide for charging the solid cleaning composition of the present invention, or a guide for water. May be provided. According to the mark, the solid cleaning composition of the present invention and water may be added in required amounts. Further, the cleaning tray may have a mesh structure. The object may be subjected to ultrasonic cleaning in the cleaning layer while being placed on the cleaning tray. When removing the object from the cleaning layer after ultrasonic cleaning, the object may be removed together with the cleaning tray on which the object is placed.

  The ultrasonic cleaner may or may not have a lid, and may have, for example, a lid that covers the upper part of the cleaning layer from the viewpoint of improvement in usability. In addition, the ultrasonic cleaner may have a switch, a timer, and the like, which can switch on and off the power. Further, the ultrasonic cleaner may be used by connecting a power cord or a power plug, or may be a battery type.

Cleaning Set The cleaning set of the present invention includes the solid cleaning composition and an ultrasonic cleaner. The washing set of the present invention may further include an instruction manual, a washing tray, a clock holder, a timer, and the like, if necessary.

  When using the set of the present invention, the method is not limited as long as the object to be cleaned can be cleaned, but from the viewpoint of performing efficient cleaning, usually in the cleaning layer, at least the solid cleaning composition of the present invention. , Water and the object to be cleaned, and then sonication is preferably performed.

  According to the combination of the solid cleaning composition of the present invention and an ultrasonic cleaning device, the object to be cleaned can be cleaned in a short time, and a dirt removing effect and a germicidal effect can be obtained. Conventionally, in cleaning using only a solid cleaning composition, a long time such as several hours was required to obtain a desired cleaning effect. According to the present invention, for example, a dirt removing effect and a germicidal effect can be obtained even with a processing time of only 5 minutes as shown in Examples described later. For this reason, according to the cleaning set of the present invention, a cleaning effect can be obtained simply and efficiently.

  Accordingly, the present invention provides a cleaning method characterized by combining a solid cleaning composition containing an oxygen-based bleaching agent with an ultrasonic cleaner. The method is not limited as long as the solid cleaning composition of the present invention is used in combination with the ultrasonic cleaner in cleaning the object, and the embodiments thereof are as described above.

Hereinafter, the present invention will be described in more detail with reference to Examples, but the present invention is not limited thereto.
Test example 1
Preparation of Solid Cleaning Composition According to the composition shown in Table 1, the components were mixed to prepare solid cleaning compositions containing three types of oxygen-based bleaching agents (solid cleaning compositions 1 to 3, respectively).

  Specifically, each component was mixed and tablet-molded at 3 MPa using a mold having a diameter of 17φ to prepare a solid washing composition in the form of tablets of 2.65 g per piece. The tablet had a diameter of 24.8 mm and a thickness of 3.48 mm.

The main components used in producing each composition are as follows.
Sodium hydrogen persulfate trade name Oxone, manufactured by LANXESS; sodium perborate trade name, SODIUM PERBORATE MONOHYDRATE, manufactured by BELINKA; citric acid trade name, citric acid (anhydrous); Showa Kako; malic acid trade name, Fusou malate S, Sodium ash light, manufactured by Tokuyama; sodium bicarbonate, manufactured by Tokuyama; sodium bicarbonate, manufactured by Tokuyama; disodium dihydrogen pyrophosphate; manufactured by Sodium Acid Pyrophosphate Food Additive, Aditya Birla Chemicals .

Ultrasonic cleaner An ultrasonic cleaner as shown in the model diagram of FIG. 1 was used as the ultrasonic cleaner.

  The ultrasonic cleaner has a cleaning layer capable of accommodating the solid cleaning composition, water, and a slide glass or a resin plate described below, and can clean the slide glass or the resin plate by ultrasonic waves. Was. The ultrasonic cleaner could further use a cleaning tray large enough to be accommodated in the cleaning layer. The volume of the washing layer is 250 mL. The test was performed at a frequency of 40 kHz and an output of 15 W.

Soil removal evaluation This test was performed by the leanut test method according to the method specified in JIS K3362 7.2 (2008) “Evaluation method of detergency of synthetic detergent for kitchen”.

  In this test, 20 g of beef tallow, 20 g each of soybean oil, and 0.25 g of oleic acid monoglyceride were dissolved in 174 g of chloroform to prepare a soil bath. This stain was attached to a slide glass to prepare a test piece.

  The washing tray was placed on the washing layer, and one tablet prepared as described above was placed in the center of the washing tray. Next, 150 mL of water at 25 ° C. was poured into the washing layer, one test piece obtained as described above was placed directly above the tablet, and the ultrasonic cleaner was turned on to wash for 5 minutes. went. This was designated as "Yes" in the ultrasonic cleaner (n = 6 for each composition).

  In addition, as an ultrasonic cleaner “none”, 150 mL of water at 25 ° C. was poured into a glass beaker, and one tablet prepared as described above was charged therein, and then immediately obtained as described above. One test piece was placed directly above the tablet and washed for 5 minutes (n = 6 for each composition).

  Ultrasonic cleaners “with” and “without” differ in the use of a cleaning layer and a glass beaker, and in the order of charging tablets and water, but do not affect the cleaning effect.

  In addition, the thing which carried out the ultrasonic cleaning device similarly for 5 minutes without putting a tablet in the said ultrasonic cleaning device "Yes" (comparative example 4 mentioned later) was made into a target.

  One tablet prepared as described above was placed in 150 mL of purified water at 25 ° C., and the tablet was completely dissolved and the pH was measured. A pH meter model F-53 (manufactured by Horiba, Ltd.) was used for the measurement.

  The dirt removal rate was calculated using the following equation. Specifically, first, the stain removal rate A for each test piece was calculated, and the average value of the stain removal rate A of a total of six test pieces was used as the stain removal rate (%).

Soil removal rate A (%) = {(soil adhesion amount before washing−soil adhesion amount after washing) / soil adhesion amount before washing} × 100

  Here, “the amount of soil attached before cleaning” is a value obtained by subtracting the mass of the slide glass before the adhesion of the sample from the mass of the test sample measured immediately after the preparation of the sample (the application of the soil). The “amount of soil attached after washing” is a value obtained by subtracting the mass of the slide glass before the soil attachment from the mass of the test piece measured after washing and lightly removing water as described above.

  The larger the value, the higher the dirt removal rate.

Using the Candida albicans NBRC1595 (purchased from the National Institute of Technology and Evaluation), an evaluation test of the eradication effect was performed according to the following procedure. Candida bacteria are known to adhere to dentures and cause odors and stains.

(1) Culture of Candida albicans NBRC1595 strain A strain obtained by culturing overnight at 35 ° C. in a potato dextrose agar medium (manufactured by Kojin Bio Co.) was added to a TSB medium (Trypticase Soy Broth, manufactured by BD) with 5% sucrose. (5% sucrose TSB medium), and appropriately diluted using a spectrophotometer so that the turbidity (OD600) at 600 nm was 0.150.

  Next, a 3 × 3 cm PMMA resin plate treated with albumin adjusted to 100 μg / mL was placed in a 6-well plate, one per well, and then 5 mL of the bacterial solution obtained by dilution as described above was added. At 35 ° C. for 18 hours to form a biofilm on the resin plate.

(2) Bactericidal test After the culture, the resin plate was slowly removed from the well, and then the resin plate was washed. Washing was performed as follows (n = 6).

The washing tray was placed on the washing layer, and one tablet prepared as described above was placed in the center of the washing tray. Next, 150 mL of water at 25 ° C. was poured into the washing layer, one of the resin plates obtained as described above was put in such a manner as not to touch the tablets, the ultrasonic cleaner was turned on, and washing was performed for 5 minutes. This was designated as "with" the ultrasonic cleaner.
Further, as an ultrasonic washer “none”, 150 mL of water at 25 ° C. was poured into a glass beaker, and one tablet prepared as described above was charged therein, and then immediately obtained as described above. One resin plate was placed without touching the tablets, and washed for 5 minutes.
Ultrasonic cleaners "with" and "without" differ in the use of a cleaning layer and a glass beaker and in the order of charging tablets and water, but do not affect the disinfection effect.
In addition, the thing which carried out the ultrasonic cleaning device similarly for 5 minutes without putting a tablet in the said ultrasonic cleaning device "Yes" (comparative example 4 mentioned later) was made into a target.

  Next, the washed resin plate is put into an SCDLP liquid medium (Soybean-Casein Digest Broth with Lecithin & Polysorbate 8, manufactured by Daigo), and the biofilm is peeled off from the resin plate using a cell lifter (manufactured by Violamo) to suspend the suspension. The resulting suspension was used to prepare a 10-fold dilution series, and 100 μL of each of the 10-fold, 100-fold, and 1000-fold dilutions was GPLP agar medium (Glucose Peptone Agar with Lecithin & Polysorbate 80, Daigo After the cells were cultured at 35 ° C. for 24 hours, the number of colonies that grew (the number of colonies per 1 mL of the suspension) was counted. This was defined as “the number of colonies after washing” in the following equation.

  The eradication rate was calculated using the following equation. Specifically, first, the disinfection rate A for each resin plate was calculated, and the average value of the disinfection rates A for a total of six resin plates was defined as the disinfection rate (%) in the disinfection test.

Eradication rate A (%) = {1- (number of colonies after washing / number of unwashed colonies)} × 100

  In this formula, the “number of unwashed colonies” is the number of colonies that were tested and counted in the same manner as the number of colonies after washing, except that the step of washing with tablets was omitted in the above (2).

  A larger value indicates a higher eradication rate.

Results The results are shown in Table 1.

  In this test, as described above, three types of solid cleaning compositions 1 to 3 were prepared, and in Table 1, the ultrasonic cleaning device “Yes” using the solid cleaning composition 1 was used in Example 1, An ultrasonic cleaner “none” using the solid cleaning composition 1 was used as Comparative Example 1. Similarly, with respect to the solid cleaning compositions 2 and 3, the ultrasonic cleaner “Yes” was set to Examples 2 and 3, respectively, and the ultrasonic cleaner “No” was set to Comparative Examples 2 and 3, respectively. Comparative Example 4 was obtained by performing ultrasonic treatment without using the solid cleaning composition.

  As is clear from Table 1, Comparative Examples 1 to 3 (only cleaning with the solid cleaning compositions 1 to 3 and no ultrasonic treatment were performed) and Comparative Example 4 (only ultrasonic treatment was performed and the solid cleaning composition was used) In the case of cleaning with the objects 1 to 3), the soil removal rate was at most 44% (Comparative Example 4), and the germicidal rate was at most 63% (Comparative Example 4).

  On the other hand, in Examples 1 to 3 (the cleaning was performed by using the solid cleaning compositions 1 to 3 in combination with the ultrasonic treatment), in each of the stain removal rate and the bacteria removal rate, Comparative Examples 1 to 3 were used. 4 greatly exceeded. In particular, the soil removal rate when the solid cleaning composition and the ultrasonic treatment are combined significantly exceeds Comparative Examples 1 to 4, and, particularly, in Example 1, the soil removal rate and the sterilization rate are both low. And significantly higher than Comparative Examples 1-4.

  From these facts, it can be seen that the combination of the solid cleaning composition containing the oxygen-based bleach and the ultrasonic treatment makes it possible to more effectively clean dentures and the like in a short time while using the solid cleaning composition. Was.

Test example 2
Test Procedure A test was performed in the same manner as in Test Example 1 except that the test was performed using the solid cleaning composition 1 prepared in Test Example 1 with the output of the ultrasonic cleaner set to 3 to 35 W.

Results The results are shown in Table 2.

  As is evident from Table 2, in all the outputs (Examples 1 and 4 to 8), a desirable stain removing effect and a sterilizing effect were obtained. In Examples 1 and 4 to 8, the stain removal rate and the bacteria elimination rate were higher than those of Comparative Examples 1 to 4 described in Test Example 1.

  From this, it can be seen that according to the combination of the solid cleaning composition containing the oxygen bleach and the ultrasonic treatment, the denture and the like can be more effectively cleaned in a short time while using the solid cleaning composition. Was.

Claims (6)

    A cleaning set comprising a solid cleaning composition containing an oxygen bleach and an ultrasonic cleaner. The cleaning set according to claim 1, wherein an output of the ultrasonic cleaning device is 3 to 35W. The washing set according to claim 1 or 2, wherein a solution obtained by dissolving 2.65 g of the solid washing composition in 150 mL of water at 25 ° C has a pH of less than 7.5. The cleaning set according to any one of claims 1 to 3, wherein the oxygen bleach is at least one selected from the group consisting of hydrogen persulfate, perborate, percarbonate and persulfate. . The cleaning set according to any one of claims 1 to 4, which is used for cleaning an oral appliance. A cleaning method comprising combining a solid cleaning composition containing an oxygen bleach and an ultrasonic cleaner.

Images