IS7883A - Bakteríueyðandi indólón oxasólidínón, milliefni til framleiðslu þeirra og lyfjasametningar sem innihalda þau - Google Patents
Bakteríueyðandi indólón oxasólidínón, milliefni til framleiðslu þeirra og lyfjasametningar sem innihalda þauInfo
- Publication number
- IS7883A IS7883A IS7883A IS7883A IS7883A IS 7883 A IS7883 A IS 7883A IS 7883 A IS7883 A IS 7883A IS 7883 A IS7883 A IS 7883A IS 7883 A IS7883 A IS 7883A
- Authority
- IS
- Iceland
- Prior art keywords
- indolone
- oxazolidinone
- bactericidal
- intermediates
- pharmaceutical compositions
- Prior art date
Links
- 230000000844 anti-bacterial effect Effects 0.000 title 1
- QSOIEACKWAXLAR-UHFFFAOYSA-N indol-2-one 1,3-oxazolidin-2-one Chemical compound O=C1NCCO1.C1=CC=CC2=NC(=O)C=C21 QSOIEACKWAXLAR-UHFFFAOYSA-N 0.000 title 1
- 239000000543 intermediate Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Indole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US44973403P | 2003-02-24 | 2003-02-24 | |
| PCT/IB2004/000466 WO2004074282A1 (en) | 2003-02-24 | 2004-02-12 | Antibacterial indolone oxazolidinones, intermediates for their preparation and pharmaceutical compositions containing them |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IS7883A true IS7883A (is) | 2005-06-09 |
Family
ID=32908714
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IS7883A IS7883A (is) | 2003-02-24 | 2005-06-09 | Bakteríueyðandi indólón oxasólidínón, milliefni til framleiðslu þeirra og lyfjasametningar sem innihalda þau |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US7012088B2 (is) |
| EP (1) | EP1599470A1 (is) |
| JP (1) | JP3887396B2 (is) |
| KR (1) | KR100701226B1 (is) |
| CN (1) | CN100349892C (is) |
| AP (1) | AP2005003375A0 (is) |
| AU (1) | AU2004213246A1 (is) |
| BR (1) | BRPI0406824A (is) |
| CA (1) | CA2515984A1 (is) |
| CO (1) | CO5601039A2 (is) |
| CR (1) | CR7956A (is) |
| EA (1) | EA009725B1 (is) |
| EC (1) | ECSP055980A (is) |
| GE (1) | GEP20084306B (is) |
| HK (1) | HK1082253A1 (is) |
| HR (1) | HRP20050658A2 (is) |
| IS (1) | IS7883A (is) |
| MA (1) | MA27661A1 (is) |
| MX (1) | MXPA05008960A (is) |
| NO (1) | NO20052794L (is) |
| OA (1) | OA13032A (is) |
| PL (1) | PL377428A1 (is) |
| RS (1) | RS20050649A (is) |
| TN (1) | TNSN05202A1 (is) |
| UA (1) | UA80326C2 (is) |
| WO (1) | WO2004074282A1 (is) |
| ZA (1) | ZA200505225B (is) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7141588B2 (en) * | 2002-02-25 | 2006-11-28 | Pfizer, Inc. | N-aryl-2-oxazolidinone-5-carboxamides and their derivatives |
| AP2007003904A0 (en) * | 2004-08-06 | 2007-02-28 | Pharmacia & Upjohn Co Llc | Oxazolidinones containing oxindoles as antibacterial agents |
| CA2603943A1 (en) * | 2005-04-06 | 2006-10-12 | Pharmacia & Upjohn Company Llc | An oxindole oxazolidinone as antibacterial agent |
| AU2006231919A1 (en) * | 2005-04-06 | 2006-10-12 | Pharmacia & Upjohn Company Llc | 7-fluoro-1,3-dihydro-indol-2-one oxazolidinones as antibacterial agents |
| GEP20115364B (en) | 2005-05-10 | 2011-12-26 | Intermune Inc | Method for modulation of stress-activated protein kinase system |
| WO2007088478A1 (en) * | 2006-02-01 | 2007-08-09 | Pfizer Products Inc. | Indazole oxazolidinones as antibacterial agents |
| CA2637158A1 (en) * | 2006-02-08 | 2007-08-16 | Pfizer Products Inc. | Oxazolidinones containing oxindoles as antibacterial agents |
| EP2296653B1 (en) | 2008-06-03 | 2016-01-27 | Intermune, Inc. | Compounds and methods for treating inflammatory and fibrotic disorders |
| FR2948940B1 (fr) * | 2009-08-04 | 2011-07-22 | Servier Lab | Nouveaux derives dihydroindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| JP5685384B2 (ja) * | 2010-03-29 | 2015-03-18 | 公益財団法人相模中央化学研究所 | ３，３−ジフルオロ−２，３−ジヒドロインドール−２−オン誘導体の製造方法 |
| AR092742A1 (es) | 2012-10-02 | 2015-04-29 | Intermune Inc | Piridinonas antifibroticas |
| EP2910547B1 (en) * | 2012-10-17 | 2017-06-14 | Okayama University | Compound; tautomer and geometric isomer thereof; salt of said compound, tautomer, or geometric isomer; method for manufacturing said compound, tautomer, isomer, or salt; antimicrobial agent; and anti-infective drug |
| CN103193794B (zh) * | 2013-04-12 | 2016-04-06 | 中国药科大学 | 一种异吲哚酮并异噁唑类稠环化合物及其合成方法 |
| MX2016012808A (es) | 2014-04-02 | 2017-01-05 | Intermune Inc | Piridinonas anti-fibroticas. |
| CN107151225B (zh) * | 2017-06-30 | 2020-05-08 | 贵州大学 | 2-羟基吲哚类衍生物、其制备方法和用途 |
| CN113773306B (zh) * | 2021-10-29 | 2023-11-10 | 四川农业大学 | 3,3-二取代吲哚酮类化合物及其制备方法和应用 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5164510A (en) * | 1988-09-15 | 1992-11-17 | The Upjohn Company | 5'Indolinyl-5β-amidomethyloxazolidin-2-ones |
| EP0359418B1 (en) | 1988-09-15 | 1994-10-12 | The Upjohn Company | 5'-Indolinyl-5beta-amidomethyloxazolidin-2-ones, 3-(fused-ring substituted)phenyl-5beta-amidomethyloxazolidin-2-ones and 3-(nitrogen substituted)phenyl-5beta-amidomethyloxazolidin-2-ones |
| US5225565A (en) * | 1988-09-15 | 1993-07-06 | The Upjohn Company | Antibacterial 3-(fused-ring substituted)phenyl-5β-amidomethyloxazolidin-2-ones |
| MY115155A (en) | 1993-09-09 | 2003-04-30 | Upjohn Co | Substituted oxazine and thiazine oxazolidinone antimicrobials. |
| DE19514313A1 (de) * | 1994-08-03 | 1996-02-08 | Bayer Ag | Benzoxazolyl- und Benzothiazolyloxazolidinone |
| HRP960159A2 (en) | 1995-04-21 | 1997-08-31 | Bayer Ag | Benzocyclopentane oxazolidinones containing heteroatoms |
| DE19601627A1 (de) * | 1996-01-18 | 1997-07-24 | Bayer Ag | Heteroatomhaltige Cyclopentanopyridyl-Oxazolidinone |
| DE19604223A1 (de) * | 1996-02-06 | 1997-08-07 | Bayer Ag | Neue substituierte Oxazolidinone |
| DE19805117A1 (de) | 1998-02-09 | 1999-08-12 | Bayer Ag | Neue Oxazolidinone mit azolhaltigen Tricyclen |
| HUP0103082A3 (en) | 1998-06-05 | 2002-12-28 | Astrazeneca Ab | Oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them |
| GB9812019D0 (en) * | 1998-06-05 | 1998-07-29 | Zeneca Ltd | Chemical compounds |
| GB9821938D0 (en) | 1998-10-09 | 1998-12-02 | Zeneca Ltd | Chemical compounds |
| AU1045300A (en) | 1998-11-17 | 2000-06-05 | Bayer Aktiengesellschaft | Novel heterocyclyl-substituted oxazolidone derivatives |
| DE19962924A1 (de) | 1999-12-24 | 2001-07-05 | Bayer Ag | Substituierte Oxazolidinone und ihre Verwendung |
| PE20011124A1 (es) | 2000-03-31 | 2001-10-28 | Upjohn Co | Nuevos agentes antibacterianos de benzosultam oxazolidinona |
| GB0009803D0 (en) | 2000-04-25 | 2000-06-07 | Astrazeneca Ab | Chemical compounds |
| US8048386B2 (en) | 2002-02-25 | 2011-11-01 | Cepheid | Fluid processing and control |
| PE20030044A1 (es) | 2000-11-17 | 2003-02-09 | Upjohn Co | Isoxazolinonas biciclicas de formula i |
| JP2005512975A (ja) | 2001-10-25 | 2005-05-12 | アストラゼネカ アクチボラグ | 抗菌薬として有用なイソキサゾリン誘導体 |
-
2004
- 2004-01-22 US US10/762,838 patent/US7012088B2/en not_active Expired - Fee Related
- 2004-02-12 CA CA002515984A patent/CA2515984A1/en not_active Abandoned
- 2004-02-12 GE GEAP20048948A patent/GEP20084306B/en unknown
- 2004-02-12 JP JP2005518544A patent/JP3887396B2/ja not_active Expired - Fee Related
- 2004-02-12 MX MXPA05008960A patent/MXPA05008960A/es active IP Right Grant
- 2004-02-12 WO PCT/IB2004/000466 patent/WO2004074282A1/en active Application Filing
- 2004-02-12 EP EP04710451A patent/EP1599470A1/en not_active Withdrawn
- 2004-02-12 AU AU2004213246A patent/AU2004213246A1/en not_active Abandoned
- 2004-02-12 BR BR0406824-6A patent/BRPI0406824A/pt not_active IP Right Cessation
- 2004-02-12 OA OA1200500233A patent/OA13032A/en unknown
- 2004-02-12 CN CNB2004800027371A patent/CN100349892C/zh not_active Expired - Fee Related
- 2004-02-12 AP AP2005003375A patent/AP2005003375A0/xx unknown
- 2004-02-12 PL PL377428A patent/PL377428A1/pl not_active Application Discontinuation
- 2004-02-12 KR KR1020057015556A patent/KR100701226B1/ko not_active IP Right Cessation
- 2004-02-12 RS YUP-2005/0649A patent/RS20050649A/sr unknown
- 2004-02-12 EA EA200501341A patent/EA009725B1/ru not_active IP Right Cessation
- 2004-12-02 UA UAA200509025A patent/UA80326C2/uk unknown
-
2005
- 2005-06-09 NO NO20052794A patent/NO20052794L/no not_active Application Discontinuation
- 2005-06-09 IS IS7883A patent/IS7883A/is unknown
- 2005-06-28 ZA ZA200505225A patent/ZA200505225B/en unknown
- 2005-07-19 HR HR20050658A patent/HRP20050658A2/hr not_active Application Discontinuation
- 2005-08-19 CO CO05082195A patent/CO5601039A2/es not_active Application Discontinuation
- 2005-08-22 CR CR7956A patent/CR7956A/es unknown
- 2005-08-24 TN TNP2005000202A patent/TNSN05202A1/fr unknown
- 2005-08-24 MA MA28456A patent/MA27661A1/fr unknown
- 2005-08-24 EC EC2005005980A patent/ECSP055980A/es unknown
-
2006
- 2006-04-11 HK HK06104354A patent/HK1082253A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EA200501341A1 (ru) | 2006-02-24 |
| HRP20050658A2 (en) | 2005-12-31 |
| UA80326C2 (en) | 2007-09-10 |
| US7012088B2 (en) | 2006-03-14 |
| BRPI0406824A (pt) | 2005-12-27 |
| OA13032A (en) | 2006-11-10 |
| PL377428A1 (pl) | 2006-02-06 |
| NO20052794L (no) | 2005-11-01 |
| WO2004074282A1 (en) | 2004-09-02 |
| AP2005003375A0 (en) | 2005-09-30 |
| JP2006515012A (ja) | 2006-05-18 |
| KR100701226B1 (ko) | 2007-03-29 |
| JP3887396B2 (ja) | 2007-02-28 |
| KR20050102135A (ko) | 2005-10-25 |
| US20040176610A1 (en) | 2004-09-09 |
| MXPA05008960A (es) | 2005-11-04 |
| EP1599470A1 (en) | 2005-11-30 |
| NO20052794D0 (no) | 2005-06-09 |
| CR7956A (es) | 2005-12-01 |
| CO5601039A2 (es) | 2006-01-31 |
| GEP20084306B (en) | 2008-02-11 |
| AU2004213246A1 (en) | 2004-09-02 |
| RS20050649A (en) | 2007-11-15 |
| CA2515984A1 (en) | 2004-09-02 |
| ECSP055980A (es) | 2006-01-16 |
| CN1742008A (zh) | 2006-03-01 |
| TNSN05202A1 (fr) | 2007-06-11 |
| CN100349892C (zh) | 2007-11-21 |
| MA27661A1 (fr) | 2005-12-01 |
| EA009725B1 (ru) | 2008-02-28 |
| HK1082253A1 (en) | 2006-06-02 |
| ZA200505225B (en) | 2006-11-29 |
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