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IN2014DN00144A - - Google Patents

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Publication number
IN2014DN00144A
IN2014DN00144A IN144DEN2014A IN2014DN00144A IN 2014DN00144 A IN2014DN00144 A IN 2014DN00144A IN 144DEN2014 A IN144DEN2014 A IN 144DEN2014A IN 2014DN00144 A IN2014DN00144 A IN 2014DN00144A
Authority
IN
India
Prior art keywords
formula
novel
compound
intermediates
preparation
Prior art date
Application number
Other languages
English (en)
Inventor
Lars Eklund
Lars Hansson
Tommy Lundholm
Pär Holmberg
Margus Eek
Original Assignee
Cambrex Karlskoga Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cambrex Karlskoga Ab filed Critical Cambrex Karlskoga Ab
Publication of IN2014DN00144A publication Critical patent/IN2014DN00144A/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C07D233/58Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/69Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by addition to carbon-to-carbon double or triple bonds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00Compounds having —CHO groups
    • C07C47/02Saturated compounds having —CHO groups bound to acyclic carbon atoms or to hydrogen
    • C07C47/105Saturated compounds having —CHO groups bound to acyclic carbon atoms or to hydrogen containing rings
    • C07C47/11Saturated compounds having —CHO groups bound to acyclic carbon atoms or to hydrogen containing rings monocyclic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00Compounds having —CHO groups
    • C07C47/20Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/228Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing six-membered aromatic rings, e.g. phenylacetaldehyde
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00Compounds having —CHO groups
    • C07C47/20Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/24Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02Boron compounds
    • C07F5/025Boronic and borinic acid compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IN144DEN2014 2011-07-22 2012-07-20 IN2014DN00144A (ar)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161510538P 2011-07-22 2011-07-22
PCT/GB2012/051746 WO2013014428A1 (en) 2011-07-22 2012-07-20 New processes for preparing 4-substituted imidazoles

Publications (1)

Publication Number Publication Date
IN2014DN00144A true IN2014DN00144A (ar) 2015-05-22

Family

ID=46939718

Family Applications (1)

Application Number Title Priority Date Filing Date
IN144DEN2014 IN2014DN00144A (ar) 2011-07-22 2012-07-20

Country Status (13)

Country Link
US (1) US8962862B2 (ar)
EP (1) EP2734508B1 (ar)
JP (1) JP5996647B2 (ar)
KR (1) KR101932206B1 (ar)
CN (1) CN103748077B (ar)
DK (1) DK2734508T3 (ar)
ES (1) ES2665093T3 (ar)
HR (1) HRP20180397T1 (ar)
HU (1) HUE037591T2 (ar)
IN (1) IN2014DN00144A (ar)
NO (1) NO2650436T3 (ar)
PL (1) PL2734508T3 (ar)
WO (1) WO2013014428A1 (ar)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103588711B (zh) * 2013-11-27 2015-04-08 天津炜捷制药有限公司 一种美托咪定中间体的制备方法
GB201501593D0 (en) * 2015-01-30 2015-03-18 Cambrex Karlskoga Ab New compounds and processes
KR101940663B1 (ko) 2017-08-11 2019-01-22 충남대학교산학협력단 촉매 반응부를 가지는 산화제 과잉 시험장치
KR101940662B1 (ko) 2017-08-11 2019-01-22 충남대학교산학협력단 직류전원 공급부를 가지는 산화제 과잉환경 시험장치
US12050293B2 (en) 2018-12-19 2024-07-30 Pgs Geophysical As Medetomidine compositions having improved anti-fouling characteristics
CN118772061A (zh) 2020-10-21 2024-10-15 I-技术有限公司 防污化合物
KR20240148807A (ko) 2022-03-22 2024-10-11 옵쉐스트바 스 아그라니첸너이아트볫스트벤너스찌유 "빅-즈다로비예쥐보트니흐" 메데토미딘 및 그 유도체의 제조 방법
WO2024047144A1 (en) 2022-09-01 2024-03-07 I-Tech Ab Composition protecting wood against marine woodborers
CN115745893A (zh) * 2022-11-16 2023-03-07 西安近代化学研究所 一种合成2-氰基-5-芳基-1h-咪唑类化合物的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL34269A (en) * 1969-04-10 1974-11-29 Prb Sa Process for the arylation of olefins
GB2101114B (en) * 1981-07-10 1985-05-22 Farmos Group Ltd Substituted imidazole derivatives and their preparation and use
PL361054A1 (en) * 2000-08-17 2004-09-20 Pfizer Inc. Substituted imidazoles as tafia inhibitors
EP1918282A1 (en) 2006-11-06 2008-05-07 "Joint Stock Company Grindeks" Method for preparing medetomidine and its salts
KR20100031113A (ko) 2007-05-24 2010-03-19 엘드러그 에스.에이. 1,(3),5-치환된 이미다졸, 이의 고혈압 치료 용도 및 이의 제조 방법
GB2453982B (en) * 2007-10-24 2009-09-16 Norbrook Lab Ltd Chemical process for the preparation of Medetomidine
CN101921234B (zh) * 2009-06-12 2012-05-30 中国中化股份有限公司 一种制备美托咪啶的方法
WO2011070069A1 (en) 2009-12-09 2011-06-16 I-Tech Ab Process for preparation of medetomidine

Also Published As

Publication number Publication date
CN103748077B (zh) 2016-08-17
WO2013014428A1 (en) 2013-01-31
CN103748077A (zh) 2014-04-23
HUE037591T2 (hu) 2018-09-28
ES2665093T3 (es) 2018-04-24
JP2014520901A (ja) 2014-08-25
JP5996647B2 (ja) 2016-09-21
HRP20180397T1 (hr) 2018-05-18
NO2650436T3 (ar) 2018-03-10
KR101932206B1 (ko) 2018-12-24
EP2734508A1 (en) 2014-05-28
PL2734508T3 (pl) 2018-08-31
US8962862B2 (en) 2015-02-24
KR20140068888A (ko) 2014-06-09
DK2734508T3 (en) 2018-05-22
US20140187789A1 (en) 2014-07-03
EP2734508B1 (en) 2018-02-28

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