IL67417A - Antiatherosclerotic substituted ureas,process for their preparation and pharmaceutical compositions containing them - Google Patents
Antiatherosclerotic substituted ureas,process for their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL67417A IL67417A IL67417A IL6741782A IL67417A IL 67417 A IL67417 A IL 67417A IL 67417 A IL67417 A IL 67417A IL 6741782 A IL6741782 A IL 6741782A IL 67417 A IL67417 A IL 67417A
- Authority
- IL
- Israel
- Prior art keywords
- antiatherosclerotic
- preparation
- pharmaceutical compositions
- compositions containing
- substituted ureas
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C273/00—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C273/18—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
- C07C273/1809—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety
- C07C273/1818—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety from -N=C=O and XNR'R"
- C07C273/1827—X being H
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Furan Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/342,693 US4473579A (en) | 1982-01-26 | 1982-01-26 | Antiatherosclerotic tetrasubstituted ureas and thioureas |
| US06/342,698 US4387105A (en) | 1982-01-26 | 1982-01-26 | Methods of treating atherosclerosis with dialkylureas and dialkylthioureas |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL67417A true IL67417A (en) | 1989-10-31 |
Family
ID=26993144
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL67417A IL67417A (en) | 1982-01-26 | 1982-12-05 | Antiatherosclerotic substituted ureas,process for their preparation and pharmaceutical compositions containing them |
Country Status (20)
| Country | Link |
|---|---|
| KR (1) | KR890001808B1 (xx) |
| AT (1) | AT391313B (xx) |
| AU (1) | AU562699B2 (xx) |
| CH (1) | CH654571A5 (xx) |
| DE (1) | DE3247581A1 (xx) |
| DK (1) | DK160869C (xx) |
| ES (2) | ES519246A0 (xx) |
| FI (1) | FI85013C (xx) |
| FR (1) | FR2521134B1 (xx) |
| GB (1) | GB2113684B (xx) |
| GR (1) | GR77186B (xx) |
| HU (1) | HU200746B (xx) |
| IE (1) | IE54683B1 (xx) |
| IL (1) | IL67417A (xx) |
| IT (1) | IT1203647B (xx) |
| NL (1) | NL8300269A (xx) |
| NO (1) | NO158417C (xx) |
| PL (1) | PL143836B1 (xx) |
| PT (1) | PT76138A (xx) |
| SE (1) | SE462653B (xx) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2138804A (en) * | 1983-04-27 | 1984-10-31 | Sumitomo Chemical Co | Fungicidal N-phenylcarbamates |
| GB2149394B (en) * | 1983-07-19 | 1986-09-24 | American Cyanamid Co | Ureas |
| US4818899A (en) * | 1986-12-03 | 1989-04-04 | Minnesota Mining And Manufacturing Company | Second harmonic generation by carbamic acid derivatives |
| DE68911203T2 (de) * | 1988-03-30 | 1994-04-14 | Warner Lambert Co | N-[[(2,6-disubstituierte)phenyl]N'- arylalkyl] Harnstoffe als antihypercholesterolemische und antiatherosclerotische Mittel. |
| US5116848A (en) * | 1988-03-30 | 1992-05-26 | Warner-Lambert Company | N-(((2,6-disubstituted)phenyl)-n-diarylalkyl)ureas as antihyperlipidemic and antiatherosclerotic agents |
| WO1991011994A1 (en) * | 1990-02-14 | 1991-08-22 | Chugai Seiyaku Kabushiki Kaisha | Inhibitor of denatured ldl formation |
| US5668136A (en) * | 1990-09-25 | 1997-09-16 | Eisai Co., Ltd. | Trisubstituted benzene derivatives, composition and methods of treatment |
| HUT62558A (en) * | 1991-07-01 | 1993-05-28 | Sandoz Ag | Process for producing n-phenylthiourea derivaties and pharmaceutical compositions comprising same |
| CA2115915A1 (en) * | 1992-07-20 | 1994-02-03 | Kenji Hayashi | Benzene derivatives |
| AU8534198A (en) * | 1997-08-05 | 1999-03-01 | Novo Nordisk A/S | Derivatives of 2,5- and 3,5-disubstituted anilines, their preparation and use |
| US6455566B1 (en) | 1997-09-03 | 2002-09-24 | Wyeth | Substituted 1-aryl-3-heteroaryl-thioureas (or isothioureas) as antiatherosclerotic agents |
| TW415942B (en) * | 1997-09-03 | 2000-12-21 | American Home Prod | Novel substituted 1-aryl-3-heteroaryl-thioureas and substituted 1-aryl-3-heteroaryl-isothioureas as antiatherosclerotic agents |
| JP2001501979A (ja) * | 1998-01-21 | 2001-02-13 | ザイモジェネティクス，インコーポレイティド | カルシトニン擬態物としてのジアルキルウレア |
| WO2009009122A2 (en) * | 2007-07-10 | 2009-01-15 | Amgen Inc. | Derivatives of urea and related diamines, methods for their manufacture, and uses therefor |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL92838C (xx) * | 1949-12-06 | |||
| US2688039A (en) * | 1952-02-08 | 1954-08-31 | Ciba Pharm Prod Inc | Halogen-containing di-(substituted phenyl)-thioureas |
| US3326663A (en) * | 1964-09-25 | 1967-06-20 | Shell Oil Co | Herbicidal phenylureas |
| US3335142A (en) * | 1965-07-07 | 1967-08-08 | American Cyanamid Co | Process for the preparation of n, n'-disubstituted ureas |
| US3659012A (en) * | 1969-05-26 | 1972-04-25 | Lilly Co Eli | Methods of treating helminth infections with thiourea derivatives |
| US3728386A (en) * | 1970-07-27 | 1973-04-17 | Exxon Research Engineering Co | N-cycloalkylalkyl and n-cycloalkyl substituted phenyl ureas and halo acetamides |
| US3928437A (en) * | 1970-09-02 | 1975-12-23 | Ciba Geigy Corp | Phenoxy-phenyl, phenylthiophenyl, phenylsulfonylphenyl and phenylaminophenyl diaminothioureas |
| US3856952A (en) * | 1973-03-01 | 1974-12-24 | Pennwalt Corp | Synergistic antimicrobial compositions employing certain n-(phenyl-carbamyl)amino-benzene sulfonyl flourides |
| US3903130A (en) * | 1974-05-03 | 1975-09-02 | Stauffer Chemical Co | 1-Trifluormethylphenyl-3-dicyanophenyl urea |
| DE2928485A1 (de) * | 1979-07-14 | 1981-01-29 | Bayer Ag | Verwendung von harnstoffderivaten als arzneimittel bei der behandlung von fettstoffwechselstoerungen |
-
1982
- 1982-12-05 IL IL67417A patent/IL67417A/xx not_active IP Right Cessation
- 1982-12-22 DE DE19823247581 patent/DE3247581A1/de not_active Withdrawn
- 1982-12-28 KR KR8205843A patent/KR890001808B1/ko active
-
1983
- 1983-01-14 GR GR70261A patent/GR77186B/el unknown
- 1983-01-21 AU AU10681/83A patent/AU562699B2/en not_active Ceased
- 1983-01-24 GB GB08301863A patent/GB2113684B/en not_active Expired
- 1983-01-25 FI FI830247A patent/FI85013C/fi not_active IP Right Cessation
- 1983-01-25 SE SE8300370A patent/SE462653B/sv not_active IP Right Cessation
- 1983-01-25 IE IE146/83A patent/IE54683B1/en not_active IP Right Cessation
- 1983-01-25 AT AT0023983A patent/AT391313B/de not_active IP Right Cessation
- 1983-01-25 DK DK028683A patent/DK160869C/da not_active IP Right Cessation
- 1983-01-25 NO NO830238A patent/NO158417C/no unknown
- 1983-01-25 CH CH404/83A patent/CH654571A5/de not_active IP Right Cessation
- 1983-01-25 IT IT47605/83A patent/IT1203647B/it active
- 1983-01-25 NL NL8300269A patent/NL8300269A/nl not_active Application Discontinuation
- 1983-01-25 FR FR8301082A patent/FR2521134B1/fr not_active Expired
- 1983-01-25 PL PL1983240284A patent/PL143836B1/pl unknown
- 1983-01-25 HU HU83227A patent/HU200746B/hu not_active IP Right Cessation
- 1983-01-25 ES ES519246A patent/ES519246A0/es active Granted
- 1983-01-25 PT PT76138A patent/PT76138A/pt not_active IP Right Cessation
-
1984
- 1984-04-11 ES ES531508A patent/ES8505943A1/es not_active Expired
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE3263633D1 (en) | Imidazodiazepines, process for their preparation and pharmaceutical compositions containing them | |
| DE3461090D1 (en) | 11-beta-aryl-estradienes, process for their preparation and pharmaceutical compositions containing them | |
| DE3064173D1 (en) | Novel 20-0-acylmaytansinoids, process for their preparation and pharmaceutical compositions containing them | |
| IL72085A (en) | 13alpha-alkylgonanes,processes for their preparation and pharmaceutical compositions containing them | |
| IL70311A (en) | 4-aminoalkyl-2(3h)-indolones,process for their preparation and pharmaceutical compositions containing them | |
| IL67417A (en) | Antiatherosclerotic substituted ureas,process for their preparation and pharmaceutical compositions containing them | |
| DE3375659D1 (en) | Substituted phenylsulfonyloxybenzimidazole carbamates, process for their preparation and their application as medicaments | |
| EP0145121A3 (en) | Pyrazoloquinolines, process for their preparation, and pharmaceutical compositions containing them | |
| DE3376215D1 (en) | Aminoglycoside derivatives, processes for their preparation and pharmaceutical compositions containing them | |
| IL70488A0 (en) | Fluoromethylthiooxacephalosporins,processes for the preparation thereof and pharmaceutical and veterinary compositions containing the same | |
| ZA822388B (en) | Secondary amines, processes for their preparation, and pharmaceutical compositions containing them | |
| IL70034A0 (en) | Heterocyclic amino compounds,their preparation and pharmaceutical compositions containing them | |
| DE3361610D1 (en) | Enzyme derivatives, process for preparing them and pharmaceutical compositions containing them | |
| IL69735A (en) | 1-phenyl-1-aminoalkyl-cyclobutane derivatives,process for their preparation and pharmaceutical compositions containing them | |
| IL68680A (en) | 2,3,4-trinor-1,5-inter-m-phenylene-prostacyclin-i2-analogues,process for their preparation and pharmaceutical compositions containing them | |
| IL72123A (en) | Substituted phenylalkyl piperazinyl-and homopiperazinylpropyl ureas and-thioureas,their preparation and pharmaceutical compositions containing them | |
| IL69115A0 (en) | Novel 1-(aryl-phenoxyaryl)-3-benzoyl ureas and process for preparation thereof and pesticidal compositions comprising the same | |
| ZA834728B (en) | Trans-delta 2-prostaglandin d derivatives,process for their preparation and compositions containing them | |
| GB2138817B (en) | 4-pheny-tetrahydro-furano-pyridines, process for their preparation, and pharmaceutical compositions containing them | |
| ZA818609B (en) | Pyrimidones,process for their preparation and pharmaceutical compositions containing them | |
| IL61099A (en) | 9-deoxy-6,9alpha-imino-delta6,8-pgi analogues,process for their preparation and pharmaceutical compositions containing them | |
| DE3160797D1 (en) | 11-alpha-amino androstanes, pharmaceutical compositions containing them and processes for their preparation | |
| IL73075A0 (en) | Antihyperlipidemic n-benzoyl-sulfamates,n-benzylsulfamates and benzylsulfonamides,process for the preparation thereof and pharmaceutical compositions containing them | |
| DE3372968D1 (en) | Heterocyclyl-thio compounds, process for their preparation, pharmaceutical compositions containing them and their use | |
| DE3368046D1 (en) | Biphenylylpropionic acid derivative, process for preparing the same and pharmaceutical composition containing the same |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RH | Patent void |