Nothing Special   »   [go: up one dir, main page]

IL135911A0 - Dna 19355 polypeptide, a tumor necrosis factor homolog - Google Patents

Dna 19355 polypeptide, a tumor necrosis factor homolog

Info

Publication number
IL135911A0
IL135911A0 IL13591198A IL13591198A IL135911A0 IL 135911 A0 IL135911 A0 IL 135911A0 IL 13591198 A IL13591198 A IL 13591198A IL 13591198 A IL13591198 A IL 13591198A IL 135911 A0 IL135911 A0 IL 135911A0
Authority
IL
Israel
Prior art keywords
polypeptide
necrosis factor
tumor necrosis
dna19355
dna
Prior art date
Application number
IL13591198A
Other languages
English (en)
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of IL135911A0 publication Critical patent/IL135911A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/525—Tumour necrosis factor [TNF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IL13591198A 1997-11-18 1998-11-18 Dna 19355 polypeptide, a tumor necrosis factor homolog IL135911A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6563597P 1997-11-18 1997-11-18
US6966197P 1997-12-12 1997-12-12
PCT/US1998/024621 WO1999025834A1 (en) 1997-11-18 1998-11-18 Dna19355 polypeptide, a tumor necrosis factor homolog

Publications (1)

Publication Number Publication Date
IL135911A0 true IL135911A0 (en) 2001-05-20

Family

ID=26745805

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13591198A IL135911A0 (en) 1997-11-18 1998-11-18 Dna 19355 polypeptide, a tumor necrosis factor homolog

Country Status (12)

Country Link
US (4) US20020146389A1 (xx)
EP (1) EP1032672B1 (xx)
JP (2) JP4485049B2 (xx)
AT (1) ATE419357T1 (xx)
AU (1) AU760010B2 (xx)
CA (1) CA2308365A1 (xx)
DE (1) DE69840413D1 (xx)
DK (1) DK1032672T3 (xx)
ES (1) ES2320285T3 (xx)
IL (1) IL135911A0 (xx)
PT (1) PT1032672E (xx)
WO (1) WO1999025834A1 (xx)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6406867B1 (en) 1996-08-16 2002-06-18 Human Genome Sciences, Inc. Antibody to human endokine alpha and methods of use
WO2001040464A1 (en) * 1999-11-30 2001-06-07 Genentech, Inc. Interleukin-1-receptor associated kinase-3 (irak3) and its use in promotion or inhibition of angiogenesis and cardiovascularization
DE60038740T2 (de) * 1999-06-02 2009-07-02 Genentech, Inc., South San Francisco Stimulierung oder hemmung von angiogenese und herzvaskularisierung
JP2003504343A (ja) * 1999-07-12 2003-02-04 ジェネンテック・インコーポレーテッド 腫瘍壊死因子リガンド／レセプター相同体による血管形成及び心血管形成の促進と抑制
AU6391000A (en) * 1999-07-28 2001-02-19 Genentech Inc. Method of preventing the injury or death of retinal cells and treating ocular diseases
DE10045591A1 (de) * 2000-09-15 2002-04-04 Klaus Pfizenmaier Ortsspezifische, antikörpervermittelte Aktivierung proapoptotischer Zytokine - AMAIZe (Antibody-Mediated Apoptosis Inducing Zytokine)
US20030133936A1 (en) * 2001-07-12 2003-07-17 Byrne Michael Chapman CD25markers and uses thereof
WO2003070763A1 (en) * 2001-08-16 2003-08-28 Human Genome Sciences, Inc. Methods and compositions for treating metabolic bone diseases relating to human endokine alpha
US20060058288A1 (en) * 2002-04-08 2006-03-16 Masayuki Ii Severe sepsis preventive therapeutic agent
JP4638876B2 (ja) * 2003-05-23 2011-02-23 ワイス Ｇｉｔｒリガンド及びｇｉｔｒリガンド関連分子及び抗体及びその使用
WO2005007190A1 (en) * 2003-07-11 2005-01-27 Schering Corporation Agonists or antagonists of the clucocorticoid-induced tumour necrosis factor receptor (gitr) or its ligand for the treatment of immune disorders, infections and cancer
EP1692318A4 (en) * 2003-12-02 2008-04-02 Genzyme Corp COMPOSITIONS AND METHODS FOR DIAGNOSIS AND TREATMENT OF LUNG CANCER
US20070065889A1 (en) * 2004-12-02 2007-03-22 Roberts Bruce L Compositions and methods to diagnose and treat lung cancer
TW201605896A (zh) 2013-08-30 2016-02-16 安美基股份有限公司 Gitr抗原結合蛋白
JP6449338B2 (ja) 2014-06-06 2019-01-09 ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ グルココルチコイド誘導腫瘍壊死因子受容体（ｇｉｔｒ）に対する抗体およびその使用
MA41460A (fr) 2015-02-03 2017-12-12 Oncomed Pharm Inc Agents de liaison à la tnfrsf et leurs utilisations
WO2016196792A1 (en) 2015-06-03 2016-12-08 Bristol-Myers Squibb Company Anti-gitr antibodies for cancer diagnostics
WO2017087678A2 (en) 2015-11-19 2017-05-26 Bristol-Myers Squibb Company Antibodies against glucocorticoid-induced tumor necrosis factor receptor (gitr) and uses thereof
US10738126B2 (en) 2016-06-10 2020-08-11 Regeneron Pharmaceuticals, Inc. Anti-GITR antibodies and uses thereof
US11685787B2 (en) 2017-05-16 2023-06-27 Bristol-Myers Squibb Company Treatment of cancer with anti-GITR agonist antibodies
CA3168173A1 (en) 2020-03-06 2021-09-10 Robert Babb Anti-gitr antibodies and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5288852A (en) * 1984-03-06 1994-02-22 Dainippon Pharmaceutical Co., Ltd. Human tumor necrosis factor polypeptides
DK1666591T3 (da) * 1995-06-29 2011-05-23 Immunex Corp Cytokin der inducerer apoptose
US6406867B1 (en) * 1996-08-16 2002-06-18 Human Genome Sciences, Inc. Antibody to human endokine alpha and methods of use
DK0961831T3 (da) * 1996-08-16 2009-01-12 Human Genome Sciences Inc Humant alfa-endokin
US5998171A (en) * 1996-08-16 1999-12-07 Human Genome Sciences, Inc. Polynucleotides encoding human endokine alpha

Also Published As

Publication number Publication date
PT1032672E (pt) 2009-04-02
JP2001523459A (ja) 2001-11-27
AU1418099A (en) 1999-06-07
WO1999025834A1 (en) 1999-05-27
ES2320285T3 (es) 2009-05-20
JP4485049B2 (ja) 2010-06-16
US20060216270A1 (en) 2006-09-28
CA2308365A1 (en) 1999-05-27
DK1032672T3 (da) 2009-04-27
US20040234498A1 (en) 2004-11-25
US20020146389A1 (en) 2002-10-10
EP1032672B1 (en) 2008-12-31
EP1032672A1 (en) 2000-09-06
JP2010088448A (ja) 2010-04-22
US20070072263A1 (en) 2007-03-29
DE69840413D1 (de) 2009-02-12
ATE419357T1 (de) 2009-01-15
AU760010B2 (en) 2003-05-08

Similar Documents

Publication Publication Date Title
IL135911A0 (en) Dna 19355 polypeptide, a tumor necrosis factor homolog
IL193919A0 (en) DcR3 POLYPEPTIDE A TNFR HOMOLOG
TW428026B (en) Bifunctional protein, preparation and use
MX9603532A (es) Sistema de suministro de acido nucleico, metodo de sintesis y sus usos.
NZ504548A (en) Polypeptides and nucleic acids encoding human chordin
DE69930955D1 (de) Polypeptide mit lysophospholipaseaktivität und nukleinesäuren die sie kodieren
DE69535719D1 (de) Fas-antigenbindender ligand
DE69532532T8 (de) Chimerische papillomavirus-ahnliche partikel
HK1018961A1 (en) Apo-2 ligand
DE69836092D1 (de) Rekombinatorisches klonieren unter verwendung von nukleinsaüren mit rekombinationsstellen
AU3192889A (en) T cell activation markers
EP0237966A3 (en) Human basic fibroblast growth factor
WO1998021343A8 (en) Genes encoding telomerase proteins
DE69837475D1 (de) Polypeptide mit aminopeptidaseaktivität und dafür kodierende nukleinsäuren
IL135051A0 (en) Apo-3 ligand polypeptide
DE59712771D1 (de) Nebenhoden-spezifisches Rezeptorprotein und dessen Verwendung
ATE236983T1 (de) Durch zelldichte stimulierte protein-tyrosin- phosphatasen
EP0336383A3 (en) Novel recombinant human lymphotoxin
ZA95968B (en) Interferon alpha/beta binding protein its preparation and use
ATE288491T1 (de) Polypeptide mit 5-aminolevulinsäure synthaseaktivität und deren nukleinsäuren
PT1241179E (pt) Proteína humana possuindo actividade antiproliferativa in vitro
MX9802005A (es) Moleculas de adn circular con origen de replicacion condicional, su proceso de preparacion y su utilizacion en terapia genica.
WO2002006340A3 (en) Tetraspan protein and uses thereof
EP2033970A3 (en) Polypeptides and nucleic acids encoding the same