ID29452A - 4-okso-1,4-dihidro-3-quinolinkarboksamida sebagai agen-agen antivirus - Google Patents
4-okso-1,4-dihidro-3-quinolinkarboksamida sebagai agen-agen antivirusInfo
- Publication number
- ID29452A ID29452A IDW00200101463A ID20011463A ID29452A ID 29452 A ID29452 A ID 29452A ID W00200101463 A IDW00200101463 A ID W00200101463A ID 20011463 A ID20011463 A ID 20011463A ID 29452 A ID29452 A ID 29452A
- Authority
- ID
- Indonesia
- Prior art keywords
- quinolinkarboxamide
- okso
- dihydro
- substituted
- nr4r5
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Quinoline Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11511399P | 1999-01-08 | 1999-01-08 | |
| US13839099P | 1999-06-09 | 1999-06-09 | |
| US14061499P | 1999-06-23 | 1999-06-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ID29452A true ID29452A (id) | 2001-08-30 |
Family
ID=27381602
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IDW00200101463A ID29452A (id) | 1999-01-08 | 1999-12-22 | 4-okso-1,4-dihidro-3-quinolinkarboksamida sebagai agen-agen antivirus |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US6248736B1 (es) |
| EP (1) | EP1140851B1 (es) |
| JP (1) | JP2002534417A (es) |
| KR (1) | KR20010101428A (es) |
| CN (1) | CN1132818C (es) |
| AT (1) | ATE275134T1 (es) |
| AU (1) | AU2158300A (es) |
| BR (1) | BR9916781A (es) |
| CA (1) | CA2353634A1 (es) |
| CO (1) | CO5150150A1 (es) |
| CZ (1) | CZ20012458A3 (es) |
| DE (1) | DE69919897T2 (es) |
| EA (1) | EA004043B1 (es) |
| ES (1) | ES2228162T3 (es) |
| HK (1) | HK1041879A1 (es) |
| HU (1) | HUP0105142A3 (es) |
| ID (1) | ID29452A (es) |
| IL (1) | IL144170A0 (es) |
| MY (1) | MY118904A (es) |
| NO (1) | NO320396B1 (es) |
| NZ (1) | NZ512823A (es) |
| PE (1) | PE20001337A1 (es) |
| PL (1) | PL348769A1 (es) |
| PT (1) | PT1140851E (es) |
| SK (1) | SK8312001A3 (es) |
| TR (1) | TR200101893T2 (es) |
| TW (1) | TW593281B (es) |
| WO (1) | WO2000040563A1 (es) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6559145B2 (en) | 2000-07-12 | 2003-05-06 | Pharmacia & Upjohn Company | Heterocycle carboxamides as antiviral agents |
| US6562822B2 (en) | 2000-07-12 | 2003-05-13 | Pharmacia & Upjohn Company | Heterocyle carboxamides as antiviral agents |
| US6730682B2 (en) | 2000-07-12 | 2004-05-04 | Pharmacia & Upjohn Company | Heterocycle carboxamides as antiviral agents |
| US6682892B2 (en) * | 2000-07-13 | 2004-01-27 | Pharmacia & Upjohn Company | Method for treating herpes viruses |
| US20100074949A1 (en) | 2008-08-13 | 2010-03-25 | William Rowe | Pharmaceutical composition and administration thereof |
| EP1363887A1 (en) * | 2001-03-01 | 2003-11-26 | PHARMACIA & UPJOHN COMPANY | Substituted quinolinecarboxamides as antiviral agents |
| WO2003020728A1 (en) | 2001-08-30 | 2003-03-13 | Pharmacia & Upjohn Company | 4-THIOXO-4,7-DIHYDRO-THIENO[2,3-b]PYRIDINE-5-CARBOTHIOAMIDES AS ANTIVIRAL AGENTS |
| AR038294A1 (es) | 2002-01-14 | 2005-01-12 | Upjohn Co | Oxotieno(3,2-b)piridincarboxamidas como agentes antivirales |
| AR038117A1 (es) | 2002-01-14 | 2004-12-29 | Upjohn Co | Agentes antivirales derivados de la 4- oxo-4,7 -dihidrofuro [2,3-b]piridin-5-carboxamida |
| AR038118A1 (es) * | 2002-01-14 | 2004-12-29 | Upjohn Co | Compuestos derivados de la bencinamida del acido 7-oxo-4,7-dihidrotien[2,3-b[piridin-6-carboxilico 3-sustituido que son utiles como antivirales |
| US20040176366A1 (en) * | 2002-08-30 | 2004-09-09 | Wathen Michael W | Method of preventing or treating atherosclerosis or restenosis |
| US20040186131A1 (en) * | 2002-08-30 | 2004-09-23 | Wathen Michael W | Method of preventing or treating atherosclerosis or restenosis |
| CN100375742C (zh) * | 2002-11-20 | 2008-03-19 | 日本烟草产业株式会社 | 4-氧代喹啉化合物及其用途 |
| ATE443048T1 (de) * | 2002-11-20 | 2009-10-15 | Japan Tobacco Inc | 4-oxochinolinverbindungen und deren verwendung als hiv-integrase-inhibitoren |
| MXPA06000675A (es) | 2003-07-24 | 2006-04-19 | Astellas Pharma Inc | Derivado de quinolona o sal del mismo. |
| WO2005113509A1 (en) | 2004-05-20 | 2005-12-01 | Japan Tobacco Inc. | Novel 4-oxoquinoline compound and use thereof as hiv integrase inhibitor |
| MY134672A (en) * | 2004-05-20 | 2007-12-31 | Japan Tobacco Inc | Stable crystal of 4-oxoquinoline compound |
| EP2229945A1 (en) | 2004-05-21 | 2010-09-22 | Japan Tobacco, Inc. | Combinations comprising a 4-isoquinolone derivative and anti-HIV agents |
| EP2489659B1 (en) | 2004-06-24 | 2017-12-13 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-binding cassette transporters |
| US20070032522A1 (en) * | 2005-07-01 | 2007-02-08 | Kumar Dange V | Antiviral agents |
| ES2790700T3 (es) | 2005-12-28 | 2020-10-28 | Vertex Pharma | Composiciones farmacéuticas de la forma amorfa de N-[2,4-bis(1,1-dimetiletil)-5-hidroxifenil]-1,4-dihidro-4-oxoquinolin-3-carboxamida |
| WO2007089030A1 (en) * | 2006-02-01 | 2007-08-09 | Japan Tobacco Inc. | Use of 6-(3-chloro-2-fluorobenzyl)-1-[(2s)-1-hydroxy-3-methylbutan-2-yl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid or salt thereof for treating retrovirus infection |
| US8383819B2 (en) * | 2006-03-06 | 2013-02-26 | Japan Tobacco Inc. | Method for producing 4-oxoquinoline compound |
| DE102008036099B4 (de) | 2008-08-04 | 2014-02-13 | Steag Power Saar Gmbh | Entstickungsanlage |
| AU2010226400B2 (en) | 2009-03-20 | 2016-07-14 | Vertex Pharmaceuticals Incorporated | Process for making modulators of cystic fibrosis transmembrane conductance regulator |
| WO2011004389A2 (en) | 2009-06-18 | 2011-01-13 | Matrix Laboratories Ltd | An improved process for the preparation of elvitegravir |
| TWI522349B (zh) * | 2010-08-27 | 2016-02-21 | 歌林達股份有限公司 | 作為ｋｃｎｑ２／３調節劑之被取代之２－氧基－喹啉－３－甲醯胺 |
| EP2819670A1 (en) | 2012-02-27 | 2015-01-07 | Vertex Pharmaceuticals Incorporated | Pharmaceutical composition and administration thereof |
| EP2909193B1 (en) | 2012-10-16 | 2017-04-19 | Janssen Pharmaceutica NV | Phenyl linked quinolinyl modulators of ror-gamma-t |
| EP2909189B8 (en) | 2012-10-16 | 2017-04-19 | Janssen Pharmaceutica NV | Heteroaryl linked quinolinyl modulators of ror-gamma-t |
| EA026415B1 (ru) | 2012-10-16 | 2017-04-28 | Янссен Фармацевтика Нв | Связанные с метиленом хинолиниловые модуляторы ror-гамма-t |
| US9221804B2 (en) | 2013-10-15 | 2015-12-29 | Janssen Pharmaceutica Nv | Secondary alcohol quinolinyl modulators of RORγt |
| US10555941B2 (en) | 2013-10-15 | 2020-02-11 | Janssen Pharmaceutica Nv | Alkyl linked quinolinyl modulators of RORγt |
| KR20160070133A (ko) | 2013-10-15 | 2016-06-17 | 얀센 파마슈티카 엔.브이. | RORyt의 알킬 결합 퀴놀리닐 조절제 |
| US9284308B2 (en) | 2013-10-15 | 2016-03-15 | Janssen Pharmaceutica Nv | Methylene linked quinolinyl modulators of RORγt |
| US9328095B2 (en) | 2013-10-15 | 2016-05-03 | Janssen Pharmaceutica Nv | Heteroaryl linked quinolinyl modulators of RORgammat |
| US9624225B2 (en) | 2013-10-15 | 2017-04-18 | Janssen Pharmaceutica Nv | Quinolinyl modulators of RORγt |
| US9403816B2 (en) | 2013-10-15 | 2016-08-02 | Janssen Pharmaceutica Nv | Phenyl linked quinolinyl modulators of RORγt |
| RU2749213C2 (ru) | 2014-10-07 | 2021-06-07 | Вертекс Фармасьютикалз Инкорпорейтед | Сокристаллы модуляторов регулятора трансмембранной проводимости при кистозном фиброзе |
| CN112996789A (zh) | 2018-09-12 | 2021-06-18 | 诺华股份有限公司 | 抗病毒吡啶并吡嗪二酮化合物 |
| AU2020353055B2 (en) | 2019-09-26 | 2024-03-07 | Gilead Sciences, Inc. | Antiviral pyrazolopyridinone compounds |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2593810B1 (fr) * | 1986-01-24 | 1988-04-22 | Sanofi Sa | Derives de la quinoleine, leur procede de preparation, leur application a titre de medicaments et les compositions les renfermant |
| US4786644A (en) * | 1987-11-27 | 1988-11-22 | Hoechst-Roussel Pharmaceuticals Inc. | 1-aryl-3-quinolinecarboxamide |
| US4959363A (en) * | 1989-06-23 | 1990-09-25 | Sterling Drug Inc. | Quinolonecarboxamide compounds, their preparation and use as antivirals. |
| JPH06502845A (ja) * | 1990-09-07 | 1994-03-31 | シェリング・コーポレーション | 抗ウイルス化合物および抗高血圧化合物 |
| US5175151A (en) | 1990-09-07 | 1992-12-29 | Schering Corporation | Antiviral compounds and antihypertensive compounds |
| DE69115692T2 (de) | 1991-09-10 | 1996-08-01 | Agfa Gevaert Nv | Thermisch übertragbare fluoreszierende Verbindungen |
| CA2225552A1 (en) * | 1995-08-02 | 1997-02-13 | Chiroscience Limited | Quinolones and their therapeutic use |
| AU7333496A (en) | 1995-10-19 | 1997-05-07 | Takeda Chemical Industries Ltd. | Quinoline derivatives as gnrh antagonists |
| EP0944619B1 (en) | 1996-11-27 | 2006-10-11 | Bristol-Myers Squibb Pharma Company | Novel integrin receptor antagonists |
| HUP0101999A3 (en) | 1997-12-22 | 2003-06-30 | Upjohn Co | 4-hydroxyquinoline-3-carboxamides and hydrazides use of them and pharmaceutical compositions containing them |
-
1999
- 1999-12-17 US US09/465,670 patent/US6248736B1/en not_active Expired - Fee Related
- 1999-12-22 CN CN998151602A patent/CN1132818C/zh not_active Expired - Fee Related
- 1999-12-22 WO PCT/US1999/027959 patent/WO2000040563A1/en active Search and Examination
- 1999-12-22 BR BR9916781-6A patent/BR9916781A/pt not_active Application Discontinuation
- 1999-12-22 EA EA200100755A patent/EA004043B1/ru not_active IP Right Cessation
- 1999-12-22 CZ CZ20012458A patent/CZ20012458A3/cs unknown
- 1999-12-22 EP EP99965907A patent/EP1140851B1/en not_active Expired - Lifetime
- 1999-12-22 TR TR2001/01893T patent/TR200101893T2/xx unknown
- 1999-12-22 CA CA002353634A patent/CA2353634A1/en not_active Abandoned
- 1999-12-22 NZ NZ512823A patent/NZ512823A/en unknown
- 1999-12-22 AT AT99965907T patent/ATE275134T1/de not_active IP Right Cessation
- 1999-12-22 PL PL99348769A patent/PL348769A1/xx unknown
- 1999-12-22 JP JP2000592271A patent/JP2002534417A/ja active Pending
- 1999-12-22 KR KR1020017008641A patent/KR20010101428A/ko not_active Application Discontinuation
- 1999-12-22 PT PT99965907T patent/PT1140851E/pt unknown
- 1999-12-22 ES ES99965907T patent/ES2228162T3/es not_active Expired - Lifetime
- 1999-12-22 ID IDW00200101463A patent/ID29452A/id unknown
- 1999-12-22 SK SK831-2001A patent/SK8312001A3/sk unknown
- 1999-12-22 AU AU21583/00A patent/AU2158300A/en not_active Abandoned
- 1999-12-22 IL IL14417099A patent/IL144170A0/xx unknown
- 1999-12-22 HU HU0105142A patent/HUP0105142A3/hu unknown
- 1999-12-22 DE DE69919897T patent/DE69919897T2/de not_active Expired - Fee Related
- 1999-12-24 MY MYPI99005719A patent/MY118904A/en unknown
- 1999-12-28 PE PE1999001326A patent/PE20001337A1/es not_active Application Discontinuation
- 1999-12-29 CO CO99081336A patent/CO5150150A1/es unknown
-
2000
- 2000-01-07 TW TW089100222A patent/TW593281B/zh not_active IP Right Cessation
-
2001
- 2001-07-06 NO NO20013379A patent/NO320396B1/no unknown
-
2002
- 2002-05-07 HK HK02103436A patent/HK1041879A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CZ20012458A3 (cs) | 2001-12-12 |
| EP1140851B1 (en) | 2004-09-01 |
| CN1132818C (zh) | 2003-12-31 |
| SK8312001A3 (en) | 2001-12-03 |
| KR20010101428A (ko) | 2001-11-14 |
| AU2158300A (en) | 2000-07-24 |
| IL144170A0 (en) | 2002-05-23 |
| CN1332729A (zh) | 2002-01-23 |
| NZ512823A (en) | 2003-10-31 |
| BR9916781A (pt) | 2001-12-04 |
| DE69919897D1 (en) | 2004-10-07 |
| DE69919897T2 (de) | 2005-09-08 |
| EA200100755A1 (ru) | 2001-12-24 |
| HK1041879A1 (en) | 2002-07-26 |
| TR200101893T2 (tr) | 2001-11-21 |
| US6248736B1 (en) | 2001-06-19 |
| PT1140851E (pt) | 2004-12-31 |
| HUP0105142A2 (hu) | 2002-04-29 |
| PE20001337A1 (es) | 2000-11-23 |
| ATE275134T1 (de) | 2004-09-15 |
| WO2000040563A1 (en) | 2000-07-13 |
| EA004043B1 (ru) | 2003-12-25 |
| JP2002534417A (ja) | 2002-10-15 |
| NO20013379D0 (no) | 2001-07-06 |
| TW593281B (en) | 2004-06-21 |
| NO320396B1 (no) | 2005-11-28 |
| EP1140851A1 (en) | 2001-10-10 |
| MY118904A (en) | 2005-02-28 |
| HUP0105142A3 (en) | 2002-05-28 |
| CA2353634A1 (en) | 2000-07-13 |
| CO5150150A1 (es) | 2002-04-29 |
| NO20013379L (no) | 2001-07-06 |
| PL348769A1 (en) | 2002-06-17 |
| ES2228162T3 (es) | 2005-04-01 |
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