HUE065728T2 - CEACAM5 és CD47 elleni bispecifikus antitestek - Google Patents
CEACAM5 és CD47 elleni bispecifikus antitestekInfo
- Publication number
- HUE065728T2 HUE065728T2 HUE21834934A HUE21834934A HUE065728T2 HU E065728 T2 HUE065728 T2 HU E065728T2 HU E21834934 A HUE21834934 A HU E21834934A HU E21834934 A HUE21834934 A HU E21834934A HU E065728 T2 HUE065728 T2 HU E065728T2
- Authority
- HU
- Hungary
- Prior art keywords
- antibodies against
- bispecific antibodies
- against ceacam5
- ceacam5
- bispecific
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3007—Carcino-embryonic Antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
- C07K2317/41—Glycosylation, sialylation, or fucosylation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Cell Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pens And Brushes (AREA)
- Conversion Of X-Rays Into Visible Images (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20215766 | 2020-12-18 | ||
| US202163135996P | 2021-01-11 | 2021-01-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE065728T2 true HUE065728T2 (hu) | 2024-06-28 |
Family
ID=79164846
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE21834934A HUE065728T2 (hu) | 2020-12-18 | 2021-12-17 | CEACAM5 és CD47 elleni bispecifikus antitestek |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US11753481B2 (hu) |
| EP (1) | EP4055055B1 (hu) |
| JP (1) | JP2024501809A (hu) |
| KR (1) | KR20230121772A (hu) |
| AU (1) | AU2021400227A1 (hu) |
| CA (1) | CA3193210A1 (hu) |
| CL (1) | CL2023001797A1 (hu) |
| CO (1) | CO2023009100A2 (hu) |
| ES (1) | ES2967381T3 (hu) |
| HR (1) | HRP20240213T1 (hu) |
| HU (1) | HUE065728T2 (hu) |
| IL (1) | IL301701A (hu) |
| MX (1) | MX2023007220A (hu) |
| PE (1) | PE20231386A1 (hu) |
| PL (1) | PL4055055T3 (hu) |
| RS (1) | RS65211B1 (hu) |
| WO (1) | WO2022130348A1 (hu) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2020013122A (es) * | 2018-06-03 | 2021-04-13 | Lamkap Bio Beta Ltd | Anticuerpos biespecificos contra anticuerpos biespecíficos que se unen al antígeno carcinoembrionario humano (ceacam5) y grupo de diferenciación (cd47). |
| HUE065728T2 (hu) | 2020-12-18 | 2024-06-28 | Lamkap Bio Beta Ag | CEACAM5 és CD47 elleni bispecifikus antitestek |
| WO2023170474A1 (en) * | 2022-03-07 | 2023-09-14 | Novimmune Sa | Cd28 bispecific antibodies for targeted t cell activation |
| US12122850B2 (en) * | 2022-03-14 | 2024-10-22 | LamKap Bio gamma AG | Bispecific GPC3xCD28 and GPC3xCD3 antibodies and their combination for targeted killing of GPC3 positive malignant cells |
| WO2023242351A1 (en) | 2022-06-16 | 2023-12-21 | Lamkap Bio Beta Ag | Combination therapy of bispecific antibodies against ceacam5 and cd47 and bispecific antibodies against ceacam5 and cd3 |
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| US20040132101A1 (en) | 2002-09-27 | 2004-07-08 | Xencor | Optimized Fc variants and methods for their generation |
| IL149820A0 (en) | 2002-05-23 | 2002-11-10 | Curetech Ltd | Humanized immunomodulatory monoclonal antibodies for the treatment of neoplastic disease or immunodeficiency |
| US7232888B2 (en) | 2002-07-01 | 2007-06-19 | Massachusetts Institute Of Technology | Antibodies against tumor surface antigens |
| US7521051B2 (en) | 2002-12-23 | 2009-04-21 | Medimmune Limited | Methods of upmodulating adaptive immune response using anti-PD-1 antibodies |
| EP1587540B1 (en) | 2003-01-09 | 2021-09-15 | MacroGenics, Inc. | IDENTIFICATION AND ENGINEERING OF ANTIBODIES WITH VARIANT Fc REGIONS AND METHODS OF USING SAME |
| WO2005018669A1 (en) | 2003-08-18 | 2005-03-03 | Macrogenics, Inc. | Fcϝriib-specific antibodies and methods of use thereof |
| EP1664116A4 (en) | 2003-08-22 | 2009-06-03 | Biogen Idec Inc | IMPROVED ANTIBODIES WITH CHANGED EFFECTOR FUNCTION AND MANUFACTURING METHOD THEREFOR |
| WO2005063815A2 (en) | 2003-11-12 | 2005-07-14 | Biogen Idec Ma Inc. | Fcϝ receptor-binding polypeptide variants and methods related thereto |
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| CA2565874C (en) | 2004-05-10 | 2017-10-03 | Macrogenics, Inc. | Humanized fc.gamma.riib-specific antibodies and methods of use thereof |
| WO2006085967A2 (en) | 2004-07-09 | 2006-08-17 | Xencor, Inc. | OPTIMIZED ANTI-CD20 MONOCONAL ANTIBODIES HAVING Fc VARIANTS |
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| EP1810035A4 (en) | 2004-11-10 | 2010-03-17 | Macrogenics Inc | EFFECTOR FUNCTION OBTAINED BY CREATION BY BIOLOGICAL GENE OF FC ANTIBODY REGIONS |
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| TW201741340A (zh) | 2016-05-09 | 2017-12-01 | 賽基公司 | Cd47抗體及使用其之方法 |
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| AU2018303254A1 (en) | 2017-07-21 | 2020-03-05 | Novimmune Sa | Generating multispecific antibody mixtures and methods of uses thereof |
| MX2020013122A (es) | 2018-06-03 | 2021-04-13 | Lamkap Bio Beta Ltd | Anticuerpos biespecificos contra anticuerpos biespecíficos que se unen al antígeno carcinoembrionario humano (ceacam5) y grupo de diferenciación (cd47). |
| EP3831849A1 (en) | 2019-12-02 | 2021-06-09 | LamKap Bio beta AG | Bispecific antibodies against ceacam5 and cd47 |
| HUE065728T2 (hu) | 2020-12-18 | 2024-06-28 | Lamkap Bio Beta Ag | CEACAM5 és CD47 elleni bispecifikus antitestek |
-
2021
- 2021-12-17 HU HUE21834934A patent/HUE065728T2/hu unknown
- 2021-12-17 MX MX2023007220A patent/MX2023007220A/es unknown
- 2021-12-17 IL IL301701A patent/IL301701A/en unknown
- 2021-12-17 WO PCT/IB2021/061983 patent/WO2022130348A1/en active Application Filing
- 2021-12-17 AU AU2021400227A patent/AU2021400227A1/en active Pending
- 2021-12-17 PL PL21834934.8T patent/PL4055055T3/pl unknown
- 2021-12-17 ES ES21834934T patent/ES2967381T3/es active Active
- 2021-12-17 JP JP2023537025A patent/JP2024501809A/ja active Pending
- 2021-12-17 PE PE2023001907A patent/PE20231386A1/es unknown
- 2021-12-17 KR KR1020237021786A patent/KR20230121772A/ko unknown
- 2021-12-17 RS RS20240190A patent/RS65211B1/sr unknown
- 2021-12-17 EP EP21834934.8A patent/EP4055055B1/en active Active
- 2021-12-17 HR HRP20240213TT patent/HRP20240213T1/hr unknown
- 2021-12-17 CA CA3193210A patent/CA3193210A1/en active Pending
- 2021-12-17 US US17/554,941 patent/US11753481B2/en active Active
-
2023
- 2023-06-16 CL CL2023001797A patent/CL2023001797A1/es unknown
- 2023-07-07 CO CONC2023/0009100A patent/CO2023009100A2/es unknown
- 2023-07-31 US US18/362,511 patent/US20240101705A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20240101705A1 (en) | 2024-03-28 |
| EP4055055B1 (en) | 2023-11-22 |
| MX2023007220A (es) | 2023-08-25 |
| RS65211B1 (sr) | 2024-03-29 |
| PE20231386A1 (es) | 2023-09-12 |
| US11753481B2 (en) | 2023-09-12 |
| IL301701A (en) | 2023-05-01 |
| KR20230121772A (ko) | 2023-08-21 |
| WO2022130348A1 (en) | 2022-06-23 |
| CA3193210A1 (en) | 2022-06-23 |
| EP4055055A1 (en) | 2022-09-14 |
| US20220195067A1 (en) | 2022-06-23 |
| CO2023009100A2 (es) | 2023-08-18 |
| AU2021400227A1 (en) | 2023-04-27 |
| JP2024501809A (ja) | 2024-01-16 |
| CL2023001797A1 (es) | 2024-02-09 |
| AU2021400227A9 (en) | 2024-05-30 |
| HRP20240213T1 (hr) | 2024-04-26 |
| PL4055055T3 (pl) | 2024-04-15 |
| EP4055055C0 (en) | 2023-11-22 |
| ES2967381T3 (es) | 2024-04-30 |
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