HK1251240A1 - 腫瘤特異性抗egfr抗體及其應用 - Google Patents
腫瘤特異性抗egfr抗體及其應用Info
- Publication number
- HK1251240A1 HK1251240A1 HK18110747.5A HK18110747A HK1251240A1 HK 1251240 A1 HK1251240 A1 HK 1251240A1 HK 18110747 A HK18110747 A HK 18110747A HK 1251240 A1 HK1251240 A1 HK 1251240A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- tumor
- application
- specific anti
- egfr antibody
- egfr
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title 1
Classifications
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Applications Claiming Priority (2)
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CN201510431481.6A CN106349389B (zh) | 2015-07-21 | 2015-07-21 | 肿瘤特异性抗egfr抗体及其应用 |
PCT/CN2016/090892 WO2017012567A1 (zh) | 2015-07-21 | 2016-07-21 | 肿瘤特异性抗egfr抗体及其应用 |
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HK1251240A1 true HK1251240A1 (zh) | 2019-01-25 |
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HK18110747.5A HK1251240A1 (zh) | 2015-07-21 | 2018-08-21 | 腫瘤特異性抗egfr抗體及其應用 |
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US (2) | US10927176B2 (zh) |
EP (1) | EP3327036B1 (zh) |
JP (1) | JP2018528786A (zh) |
KR (1) | KR20180053648A (zh) |
CN (1) | CN106349389B (zh) |
AU (1) | AU2016295601B2 (zh) |
CA (1) | CA2993262A1 (zh) |
DK (1) | DK3327036T3 (zh) |
ES (1) | ES2881807T3 (zh) |
HK (1) | HK1251240A1 (zh) |
RU (1) | RU2730605C2 (zh) |
SG (1) | SG11201801003YA (zh) |
WO (1) | WO2017012567A1 (zh) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
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CN106349389B (zh) * | 2015-07-21 | 2019-11-15 | 科济生物医药(上海)有限公司 | 肿瘤特异性抗egfr抗体及其应用 |
CN105331585A (zh) | 2015-11-13 | 2016-02-17 | 科济生物医药(上海)有限公司 | 携带pd-l1阻断剂的嵌合抗原受体修饰的免疫效应细胞 |
CN107326014B (zh) * | 2017-07-31 | 2019-09-24 | 时力生物科技(北京)有限公司 | 一种双特异性嵌合抗原受体修饰的t淋巴细胞及其制备方法和应用 |
WO2019052562A1 (zh) * | 2017-09-15 | 2019-03-21 | 科济生物医药(上海)有限公司 | Il-4r的融合蛋白及其应用 |
CN109796532B (zh) * | 2017-11-17 | 2024-09-10 | 恺兴生命科技(上海)有限公司 | 靶向成纤维激活蛋白α的结合单元及其应用 |
CN109836497A (zh) * | 2017-11-25 | 2019-06-04 | 深圳宾德生物技术有限公司 | 一种靶向egfr的单链抗体、嵌合抗原受体t细胞及其制备方法和应用 |
US20210340232A1 (en) * | 2018-10-15 | 2021-11-04 | Board Of Regents, The University Of Texas System | Monoclonal antibodies against human dickkopf3 and uses thereof |
JP2022517301A (ja) * | 2018-12-07 | 2022-03-08 | カファ セラピューティクス リミテッド | 腫瘍併用免疫療法 |
WO2020197318A1 (ko) * | 2019-03-28 | 2020-10-01 | 한국생명공학연구원 | Car 유전자가 도입된 nk 세포의 제조방법 및 그의 용도 |
CN109929039A (zh) * | 2019-03-28 | 2019-06-25 | 郑州大学第一附属医院 | 基于cd276抗体的嵌合抗原受体、慢病毒表达载体及其应用 |
WO2021093818A1 (zh) * | 2019-11-13 | 2021-05-20 | 上海医药集团股份有限公司 | Tmem59蛋白二聚体或嵌合表达受体改善t细胞功能 |
EP4061849A4 (en) * | 2019-11-21 | 2024-05-29 | Brown University | BISPECIFIC ANTIBODIES AGAINST CHI3L1 AND CTLA4 WITH IMPROVED CYTOTOXIC EFFECTS ON TUMOR CELLS |
CN111534532A (zh) * | 2020-03-30 | 2020-08-14 | 华东理工大学 | 噬菌体药物蛋白展示系统及其应用 |
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Publication number | Priority date | Publication date | Assignee | Title |
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ZA952174B (en) | 1994-03-17 | 1995-12-27 | Merck Patent Gmbh | Anti-EGFR single-chain fvs and anti-EGFR antibodies |
IL128852A0 (en) * | 1999-03-05 | 2000-01-31 | Compugen Ltd | Novel nucleic acid and amino acid sequences |
US20100056762A1 (en) * | 2001-05-11 | 2010-03-04 | Old Lloyd J | Specific binding proteins and uses thereof |
AU2002314491A1 (en) * | 2001-06-20 | 2003-01-02 | Compugen Ltd. | Nucleic acid and amino acid sequences of a vegf variant |
IN2012DN00313A (zh) * | 2003-06-27 | 2015-05-08 | Amgen Fremont Inc | |
US8580263B2 (en) * | 2006-11-21 | 2013-11-12 | The Regents Of The University Of California | Anti-EGFR family antibodies, bispecific anti-EGFR family antibodies and methods of use thereof |
WO2010137654A1 (ja) * | 2009-05-29 | 2010-12-02 | 株式会社未来創薬研究所 | Egfファミリーリガンドのアンタゴニストを成分とする医薬組成物 |
CN103382223B (zh) * | 2012-04-01 | 2015-06-10 | 上海益杰生物技术有限公司 | 针对表皮生长因子受体隐蔽表位和t细胞抗原的多功能抗体多肽 |
CN103113470B (zh) * | 2013-02-27 | 2015-04-22 | 四川大学 | 靶向人egfr的基因工程化淋巴细胞及其制备方法和用途 |
CN104087607B (zh) * | 2013-04-01 | 2017-06-20 | 科济生物医药(上海)有限公司 | 编码嵌合抗原受体蛋白的核酸及表达嵌合抗原受体蛋白的t淋巴细胞 |
CN106349389B (zh) * | 2015-07-21 | 2019-11-15 | 科济生物医药(上海)有限公司 | 肿瘤特异性抗egfr抗体及其应用 |
CN118146379A (zh) * | 2016-04-26 | 2024-06-07 | 科济生物医药(上海)有限公司 | 一种改善免疫应答细胞功能的方法 |
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2015
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2016
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- 2016-07-21 EP EP16827258.1A patent/EP3327036B1/en active Active
- 2016-07-21 US US15/746,711 patent/US10927176B2/en active Active
- 2016-07-21 AU AU2016295601A patent/AU2016295601B2/en not_active Expired - Fee Related
- 2016-07-21 CA CA2993262A patent/CA2993262A1/en not_active Abandoned
- 2016-07-21 ES ES16827258T patent/ES2881807T3/es active Active
- 2016-07-21 JP JP2018522842A patent/JP2018528786A/ja not_active Ceased
- 2016-07-21 KR KR1020187005181A patent/KR20180053648A/ko not_active Application Discontinuation
- 2016-07-21 DK DK16827258.1T patent/DK3327036T3/da active
- 2016-07-21 RU RU2018104703A patent/RU2730605C2/ru active
- 2016-07-21 SG SG11201801003YA patent/SG11201801003YA/en unknown
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2018
- 2018-08-21 HK HK18110747.5A patent/HK1251240A1/zh unknown
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2021
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Publication number | Publication date |
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ES2881807T3 (es) | 2021-11-30 |
RU2018104703A (ru) | 2019-08-22 |
CN106349389A (zh) | 2017-01-25 |
RU2018104703A3 (zh) | 2019-12-06 |
JP2018528786A (ja) | 2018-10-04 |
US10927176B2 (en) | 2021-02-23 |
EP3327036A1 (en) | 2018-05-30 |
SG11201801003YA (en) | 2018-03-28 |
AU2016295601B2 (en) | 2022-09-29 |
US20220017625A1 (en) | 2022-01-20 |
US20180327501A1 (en) | 2018-11-15 |
AU2016295601A1 (en) | 2018-03-15 |
WO2017012567A1 (zh) | 2017-01-26 |
CN106349389B (zh) | 2019-11-15 |
RU2730605C2 (ru) | 2020-08-24 |
CA2993262A1 (en) | 2017-01-26 |
EP3327036A4 (en) | 2019-03-13 |
EP3327036B1 (en) | 2021-05-19 |
DK3327036T3 (da) | 2021-05-31 |
KR20180053648A (ko) | 2018-05-23 |
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