HK1090090A1 - Process for the preparation of dihydroxy esters and derivatives thereof - Google Patents

Process for the preparation of dihydroxy esters and derivatives thereof

Info

Publication number: HK1090090A1
Authority: HK; Hong Kong
Prior art keywords: derivatives; preparation; dihydroxy esters; dihydroxy; esters
Prior art date: 2000-05-09

Application number

HK06110633A

Other languages

English (en)

Inventor

Robert Antony Holt

Christopher David Reeve

Andrew John Blacker

Original Assignee

Astrazeneca Uk Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-05-09

Filing date

2006-09-22

Publication date

2006-12-15

2006-09-22 Application filed by Astrazeneca Uk Ltd filed Critical Astrazeneca Uk Ltd

2006-12-15 Publication of HK1090090A1 publication Critical patent/HK1090090A1/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
- C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/03—Preparation of carboxylic acid esters by reacting an ester group with a hydroxy group
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
- C07C69/675—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids of saturated hydroxy-carboxylic acids
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
- C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/62—Carboxylic acid esters

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Wood Science & Technology (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Health & Medical Sciences (AREA)
General Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Microbiology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

HK06110633A 2000-05-09 2006-09-22 Process for the preparation of dihydroxy esters and derivatives thereof HK1090090A1 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GBGB0011120.3A GB0011120D0 (en)	2000-05-09	2000-05-09	Process

Publications (1)

Publication Number	Publication Date
HK1090090A1 true HK1090090A1 (en)	2006-12-15

Family

ID=9891211

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
HK03103991A HK1051708A1 (en)	2000-05-09	2003-06-05	Process for the preparation of dihydroxy esters and derivatives thereof
HK06110633A HK1090090A1 (en)	2000-05-09	2006-09-22	Process for the preparation of dihydroxy esters and derivatives thereof
HK07101586.1A HK1096998A1 (en)	2000-05-09	2007-02-09	Process for the preparation of dihydroxy esters and derivatives thereof

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
HK03103991A HK1051708A1 (en)	2000-05-09	2003-06-05	Process for the preparation of dihydroxy esters and derivatives thereof

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
HK07101586.1A HK1096998A1 (en)	2000-05-09	2007-02-09	Process for the preparation of dihydroxy esters and derivatives thereof

Country Status (34)

Country	Link
US (4)	US7157255B2 (xx)
EP (3)	EP1282719B1 (xx)
JP (1)	JP4733901B2 (xx)
KR (2)	KR100996977B1 (xx)
CN (1)	CN1196793C (xx)
AR (2)	AR028074A1 (xx)
AT (3)	ATE369437T1 (xx)
AU (2)	AU2001252383B2 (xx)
BR (1)	BR0110667A (xx)
CA (2)	CA2408004C (xx)
CY (3)	CY1105376T1 (xx)
CZ (3)	CZ302675B6 (xx)
DE (3)	DE60120685T2 (xx)
DK (3)	DK1657310T3 (xx)
EE (1)	EE05062B1 (xx)
ES (3)	ES2264981T3 (xx)
GB (1)	GB0011120D0 (xx)
HK (3)	HK1051708A1 (xx)
HU (1)	HUP0302216A3 (xx)
IL (4)	IL152608A0 (xx)
IS (1)	IS2290B (xx)
MX (1)	MXPA02010955A (xx)
MY (1)	MY127751A (xx)
NO (1)	NO20025377L (xx)
NZ (1)	NZ522407A (xx)
PL (3)	PL208379B1 (xx)
PT (3)	PT1657310E (xx)
RU (1)	RU2266961C2 (xx)
SI (3)	SI1282719T1 (xx)
SK (2)	SK287524B6 (xx)
TW (1)	TWI240753B (xx)
UA (1)	UA73774C2 (xx)
WO (1)	WO2001085975A1 (xx)
ZA (1)	ZA200208937B (xx)

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EP1417180B1 (en)	2001-07-13	2006-12-27	AstraZeneca UK Limited	Preparation of aminopyrimidine compounds
EP1323717A1 (en)	2001-12-27	2003-07-02	Dsm N.V.	Process for the preparation of 2-(6-Substituted-1,3-Dioxane-4-yL) acetic acid derivatives
GB0211751D0 (en) *	2002-05-22	2002-07-03	Avecia Ltd	Compound and process
EP1375493A1 (en)	2002-06-17	2004-01-02	Dsm N.V.	Process for the preparation of an dioxane acetic acid ester
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CN102373250B (zh) *	2011-11-08	2012-08-22	张家港市信谊化工有限公司	阿伐他汀钙侧链中间体的制备方法
CN102618596A (zh) *	2012-03-20	2012-08-01	中国药科大学	一种非水相体系中生物转化制备关附庚素的方法
WO2014203045A1 (en)	2013-06-20	2014-12-24	Lupin Limited	A novel, green and cost effective process for synthesis of tert-butyl (3r,5s)-6-oxo-3,5-dihydroxy-3,5-o-isopropylidene-hexanoate
CN105503816B (zh) *	2016-02-17	2018-02-13	中节能万润股份有限公司	一种固体(4R‑cis)‑6‑甲酰基‑2,2‑二甲基‑1,3‑二氧己环‑4‑乙酸叔丁酯的制备方法
CN108530416B (zh) *	2017-11-02	2020-05-12	江苏阿尔法药业有限公司	一种瑞舒伐他汀中间体的制备方法
CN109574830B (zh) *	2019-01-04	2021-04-13	浙江宏元药业股份有限公司	一种瑞舒伐他汀钙中间体及其制备方法和应用
KR102384854B1 (ko)	2021-06-15	2022-04-11	한대성	풀빅산 및 일라이트를 이용한 침대

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2000
- 2000-05-09 GB GBGB0011120.3A patent/GB0011120D0/en not_active Ceased
2001
- 2001-01-05 UA UA2002129795A patent/UA73774C2/uk unknown
- 2001-05-01 NZ NZ522407A patent/NZ522407A/en not_active IP Right Cessation
- 2001-05-01 JP JP2001582563A patent/JP4733901B2/ja not_active Expired - Lifetime
- 2001-05-01 EE EEP200200628A patent/EE05062B1/xx not_active IP Right Cessation
- 2001-05-01 CN CNB018124895A patent/CN1196793C/zh not_active Expired - Lifetime
- 2001-05-01 IL IL15260801A patent/IL152608A0/xx unknown
- 2001-05-01 AT AT06002032T patent/ATE369437T1/de active
- 2001-05-01 AU AU2001252383A patent/AU2001252383B2/en not_active Ceased
- 2001-05-01 PT PT06002032T patent/PT1657310E/pt unknown
- 2001-05-01 WO PCT/GB2001/001915 patent/WO2001085975A1/en active Application Filing
- 2001-05-01 ES ES01925699T patent/ES2264981T3/es not_active Expired - Lifetime
- 2001-05-01 DK DK06002032T patent/DK1657310T3/da active
- 2001-05-01 CZ CZ20110205A patent/CZ302675B6/cs not_active IP Right Cessation
- 2001-05-01 SI SI200130591T patent/SI1282719T1/sl unknown
- 2001-05-01 SK SK5088-2008A patent/SK287524B6/sk not_active IP Right Cessation
- 2001-05-01 US US10/275,092 patent/US7157255B2/en not_active Expired - Lifetime
- 2001-05-01 SI SI200130963T patent/SI1726658T1/sl unknown
- 2001-05-01 DE DE60120685T patent/DE60120685T2/de not_active Expired - Lifetime
- 2001-05-01 CA CA2408004A patent/CA2408004C/en not_active Expired - Fee Related
- 2001-05-01 SI SI200130758T patent/SI1657310T1/sl unknown
- 2001-05-01 HU HU0302216A patent/HUP0302216A3/hu unknown
- 2001-05-01 EP EP01925699A patent/EP1282719B1/en not_active Expired - Lifetime
- 2001-05-01 PL PL387244A patent/PL208379B1/pl not_active IP Right Cessation
- 2001-05-01 DE DE60129865T patent/DE60129865T2/de not_active Expired - Lifetime
- 2001-05-01 KR KR1020087005996A patent/KR100996977B1/ko not_active IP Right Cessation
- 2001-05-01 EP EP06019415A patent/EP1726658B1/en not_active Expired - Lifetime
- 2001-05-01 MX MXPA02010955A patent/MXPA02010955A/es active IP Right Grant
- 2001-05-01 SK SK1589-2002A patent/SK286746B6/sk not_active IP Right Cessation
- 2001-05-01 RU RU2002132884/13A patent/RU2266961C2/ru not_active IP Right Cessation
- 2001-05-01 AU AU5238301A patent/AU5238301A/xx active Pending
- 2001-05-01 PL PL359336A patent/PL208359B1/pl not_active IP Right Cessation
- 2001-05-01 CA CA002677945A patent/CA2677945A1/en not_active Abandoned
- 2001-05-01 CZ CZ20110204A patent/CZ302674B6/cs not_active IP Right Cessation
- 2001-05-01 EP EP06002032A patent/EP1657310B1/en not_active Expired - Lifetime
- 2001-05-01 BR BR0110667-8A patent/BR0110667A/pt not_active IP Right Cessation
- 2001-05-01 DK DK06019415.6T patent/DK1726658T3/da active
- 2001-05-01 ES ES06019415T patent/ES2340190T3/es not_active Expired - Lifetime
- 2001-05-01 AT AT06019415T patent/ATE458823T1/de active
- 2001-05-01 DK DK01925699T patent/DK1282719T3/da active
- 2001-05-01 DE DE60141424T patent/DE60141424D1/de not_active Expired - Lifetime
- 2001-05-01 PL PL387243A patent/PL208377B1/pl not_active IP Right Cessation
- 2001-05-01 ES ES06002032T patent/ES2289722T3/es not_active Expired - Lifetime
- 2001-05-01 PT PT06019415T patent/PT1726658E/pt unknown
- 2001-05-01 CZ CZ20023675A patent/CZ302632B6/cs not_active IP Right Cessation
- 2001-05-01 AT AT01925699T patent/ATE330020T1/de active
- 2001-05-01 PT PT01925699T patent/PT1282719E/pt unknown
- 2001-05-01 KR KR1020027014987A patent/KR100914675B1/ko not_active IP Right Cessation
- 2001-05-03 AR ARP010102091A patent/AR028074A1/es active IP Right Grant
- 2001-05-04 TW TW090110741A patent/TWI240753B/zh not_active IP Right Cessation
- 2001-05-08 MY MYPI20012105A patent/MY127751A/en unknown
2002
- 2002-11-03 IL IL152608A patent/IL152608A/en not_active IP Right Cessation
- 2002-11-04 ZA ZA200208937A patent/ZA200208937B/en unknown
- 2002-11-07 IS IS6609A patent/IS2290B/is unknown
- 2002-11-08 NO NO20025377A patent/NO20025377L/no not_active Application Discontinuation
2003
- 2003-06-05 HK HK03103991A patent/HK1051708A1/xx not_active IP Right Cessation
2006
- 2006-04-27 US US11/412,047 patent/US7416865B2/en not_active Expired - Lifetime
- 2006-09-12 CY CY20061101301T patent/CY1105376T1/el unknown
- 2006-09-22 HK HK06110633A patent/HK1090090A1/xx not_active IP Right Cessation
2007
- 2007-02-09 HK HK07101586.1A patent/HK1096998A1/xx not_active IP Right Cessation
- 2007-10-05 CY CY20071101270T patent/CY1106910T1/el unknown
2008
- 2008-07-23 US US12/178,424 patent/US7732171B2/en not_active Expired - Fee Related
- 2008-08-12 IL IL193404A patent/IL193404A/en not_active IP Right Cessation
- 2008-08-12 IL IL193405A patent/IL193405A/en not_active IP Right Cessation
- 2008-09-15 AR ARP080104001A patent/AR070946A2/es not_active Application Discontinuation
2010
- 2010-04-27 CY CY20101100376T patent/CY1109991T1/el unknown
- 2010-04-27 US US12/768,459 patent/US7888083B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
DE60129865T2 (de)	2008-05-08
PL208359B1 (pl)	2011-04-29
IS6609A (is)	2002-11-07
EE05062B1 (et)	2008-08-15
SI1657310T1 (sl)	2007-12-31
CN1440461A (zh)	2003-09-03
KR100996977B1 (ko)	2010-11-26
SK287524B6 (sk)	2011-01-04
PL208379B1 (pl)	2011-04-29
PL208377B1 (pl)	2011-04-29
AR070946A2 (es)	2010-05-19
CN1196793C (zh)	2005-04-13
EE200200628A (et)	2004-04-15
IL193405A (en)	2010-04-29
DK1282719T3 (da)	2006-10-02
EP1657310A1 (en)	2006-05-17
US7732171B2 (en)	2010-06-08
DE60141424D1 (de)	2010-04-08
CA2408004C (en)	2010-04-13
ATE369437T1 (de)	2007-08-15
NZ522407A (en)	2004-06-25
US20100209984A1 (en)	2010-08-19
US7157255B2 (en)	2007-01-02
BR0110667A (pt)	2003-03-25
CY1105376T1 (el)	2010-04-28
HUP0302216A2 (hu)	2003-10-28
HK1096998A1 (en)	2007-06-15
ES2340190T3 (es)	2010-05-31
IL152608A (en)	2009-05-04
SI1726658T1 (sl)	2010-05-31
HUP0302216A3 (en)	2011-03-28
DE60129865D1 (de)	2007-09-20
AU5238301A (en)	2001-11-20
CY1109991T1 (el)	2014-09-10
EP1282719A1 (en)	2003-02-12
AU2001252383B2 (en)	2005-04-14
CZ20023675A3 (cs)	2003-02-12
US7888083B2 (en)	2011-02-15
DE60120685T2 (de)	2007-06-14
EP1282719B1 (en)	2006-06-14
US20060194297A1 (en)	2006-08-31
WO2001085975A1 (en)	2001-11-15
CZ302675B6 (cs)	2011-08-24
KR20030032949A (ko)	2003-04-26
CA2408004A1 (en)	2001-11-15
TWI240753B (en)	2005-10-01
EP1726658A2 (en)	2006-11-29
MXPA02010955A (es)	2003-05-27
PL359336A1 (en)	2004-08-23
SK15892002A3 (sk)	2003-04-01
DK1657310T3 (da)	2007-10-29
SI1282719T1 (sl)	2006-10-31
IL193405A0 (en)	2009-02-11
ATE458823T1 (de)	2010-03-15
UA73774C2 (en)	2005-09-15
EP1726658B1 (en)	2010-02-24
US7416865B2 (en)	2008-08-26
US20030134900A1 (en)	2003-07-17
AR028074A1 (es)	2003-04-23
PT1726658E (pt)	2010-04-15
GB0011120D0 (en)	2000-06-28
ATE330020T1 (de)	2006-07-15
KR20080042129A (ko)	2008-05-14
DK1726658T3 (da)	2010-05-17
MY127751A (en)	2006-12-29
US20080280336A1 (en)	2008-11-13
NO20025377L (no)	2003-01-07
EP1726658A3 (en)	2008-12-24
ES2289722T3 (es)	2008-02-01
PT1282719E (pt)	2006-09-29
ZA200208937B (en)	2003-08-28
IS2290B (is)	2007-10-15
IL152608A0 (en)	2003-06-24
KR100914675B1 (ko)	2009-08-28
NO20025377D0 (no)	2002-11-08
ES2264981T3 (es)	2007-02-01
PT1657310E (pt)	2007-09-26
RU2266961C2 (ru)	2005-12-27
HK1051708A1 (en)	2003-08-15
CA2677945A1 (en)	2001-11-15
JP2003532427A (ja)	2003-11-05
JP4733901B2 (ja)	2011-07-27
CZ302632B6 (cs)	2011-08-10
DE60120685D1 (de)	2006-07-27
SK286746B6 (sk)	2009-04-06
CY1106910T1 (el)	2012-09-26
EP1657310B1 (en)	2007-08-08
CZ302674B6 (cs)	2011-08-24
IL193404A0 (en)	2009-02-11
IL193404A (en)	2010-04-29

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2021-05-14	PE	Patent expired	Effective date: 20210430