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GB2211413B - Pharmaceutical formulations comprising microcapsules - Google Patents

Pharmaceutical formulations comprising microcapsules

Info

Publication number
GB2211413B
GB2211413B GB8902288A GB8902288A GB2211413B GB 2211413 B GB2211413 B GB 2211413B GB 8902288 A GB8902288 A GB 8902288A GB 8902288 A GB8902288 A GB 8902288A GB 2211413 B GB2211413 B GB 2211413B
Authority
GB
United Kingdom
Prior art keywords
microcapsules
pharmaceutical formulations
formulations
pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
GB8902288A
Other languages
English (en)
Other versions
GB8902288D0 (en
GB2211413A (en
Inventor
Robert Nichol Boyes
Thomas Robert Tice
Richard Mac Gilley
Kenneth Lawrence Pledger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Innovata Biomed Ltd
Original Assignee
Innovata Biomed Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB868619519A external-priority patent/GB8619519D0/en
Priority claimed from GB878700063A external-priority patent/GB8700063D0/en
Application filed by Innovata Biomed Ltd filed Critical Innovata Biomed Ltd
Publication of GB8902288D0 publication Critical patent/GB8902288D0/en
Publication of GB2211413A publication Critical patent/GB2211413A/en
Application granted granted Critical
Publication of GB2211413B publication Critical patent/GB2211413B/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/113—Multiple emulsions, e.g. oil-in-water-in-oil

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB8902288A 1986-08-11 1989-02-02 Pharmaceutical formulations comprising microcapsules Expired - Lifetime GB2211413B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB868619519A GB8619519D0 (en) 1986-08-11 1986-08-11 Inhalation preparation
GB878700063A GB8700063D0 (en) 1987-01-05 1987-01-05 Pharmaceutical formulation
PCT/GB1987/000566 WO1988001165A1 (en) 1986-08-11 1987-08-11 Pharmaceutical formulations comprising microcapsules

Publications (3)

Publication Number Publication Date
GB8902288D0 GB8902288D0 (en) 1989-04-05
GB2211413A GB2211413A (en) 1989-07-05
GB2211413B true GB2211413B (en) 1990-03-21

Family

ID=26291161

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8902288A Expired - Lifetime GB2211413B (en) 1986-08-11 1989-02-02 Pharmaceutical formulations comprising microcapsules

Country Status (14)

Country Link
US (1) US5384133A (da)
EP (2) EP0318492A1 (da)
JP (1) JP2765700B2 (da)
KR (1) KR950014440B1 (da)
AU (1) AU612591B2 (da)
DE (1) DE3784594T2 (da)
DK (1) DK171221B1 (da)
ES (1) ES2053549T3 (da)
GB (1) GB2211413B (da)
IE (1) IE59720B1 (da)
NO (1) NO176784C (da)
NZ (1) NZ221411A (da)
PT (1) PT85521B (da)
WO (1) WO1988001165A1 (da)

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NO881533L (no) 1988-06-10
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DK171221B1 (da) 1996-08-05
KR950014440B1 (ko) 1995-11-28
EP0257915B1 (en) 1993-03-10
US5384133A (en) 1995-01-24
NO176784B (no) 1995-02-20
DE3784594D1 (de) 1993-04-15
KR880701541A (ko) 1988-11-03
AU612591B2 (en) 1991-07-18
DE3784594T2 (de) 1994-01-05
AU7754987A (en) 1988-03-08
EP0318492A1 (en) 1989-06-07
DK195988D0 (da) 1988-04-11
ES2053549T3 (es) 1994-08-01
IE59720B1 (en) 1994-03-23
PT85521A (en) 1987-09-01
GB8902288D0 (en) 1989-04-05
WO1988001165A1 (en) 1988-02-25
DK195988A (da) 1988-06-08
GB2211413A (en) 1989-07-05
JP2765700B2 (ja) 1998-06-18
JPH01503534A (ja) 1989-11-30
IE872145L (en) 1988-02-11
PT85521B (pt) 1990-06-29

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