Nothing Special   »   [go: up one dir, main page]

GB2008946A - An emulsion cream composition, process for its preparation, and method of obtaining local anesthesia - Google Patents

An emulsion cream composition, process for its preparation, and method of obtaining local anesthesia

Info

Publication number
GB2008946A
GB2008946A GB7846755A GB7846755A GB2008946A GB 2008946 A GB2008946 A GB 2008946A GB 7846755 A GB7846755 A GB 7846755A GB 7846755 A GB7846755 A GB 7846755A GB 2008946 A GB2008946 A GB 2008946A
Authority
GB
United Kingdom
Prior art keywords
oil
preparation
local anesthetic
local anesthesia
cream composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB7846755A
Other versions
GB2008946B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astra Lakemedel AB
Original Assignee
Astra Lakemedel AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE7713618A external-priority patent/SE7713618L/en
Priority claimed from SE7713617A external-priority patent/SE7713617L/en
Application filed by Astra Lakemedel AB filed Critical Astra Lakemedel AB
Publication of GB2008946A publication Critical patent/GB2008946A/en
Application granted granted Critical
Publication of GB2008946B publication Critical patent/GB2008946B/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/113—Multiple emulsions, e.g. oil-in-water-in-oil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q15/00—Anti-perspirants or body deodorants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Birds (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

An emulsion cream of improved local anesthetic effect when applied topically, which consists of an oil-in- water emulsion, in which a local anesthetic agent in base form as such or dissolved in an oil forms the oil phase of the emulsion, and the concentration of local anesthetic agent in the oil droplets is such that the oil is substantially saturated by local anesthetic agent and a substantial part of the droplets have a size not exceeding 10 microns.
GB7846755A 1977-12-01 1978-11-30 Emulsion cream composition process for its preparation andmethod of obtaining local anesthesia Expired GB2008946B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE7713618A SE7713618L (en) 1977-12-01 1977-12-01 LOCAL ANESTHETIC MIXTURE
SE7713617A SE7713617L (en) 1977-12-01 1977-12-01 ANTITRANSPIRATIVES

Publications (2)

Publication Number Publication Date
GB2008946A true GB2008946A (en) 1979-06-13
GB2008946B GB2008946B (en) 1982-06-30

Family

ID=26656921

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7846755A Expired GB2008946B (en) 1977-12-01 1978-11-30 Emulsion cream composition process for its preparation andmethod of obtaining local anesthesia

Country Status (4)

Country Link
AU (1) AU524406B2 (en)
DE (1) DE2851369A1 (en)
GB (1) GB2008946B (en)
SE (1) SE432192B (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0028110A2 (en) * 1979-10-26 1981-05-06 Smith and Nephew Associated Companies p.l.c. Autoclavable emulsions
US9308181B2 (en) 2006-03-06 2016-04-12 Nuvo Research Inc. Topical formulations, systems and methods
US9642912B2 (en) 2006-03-06 2017-05-09 Crescita Therapeutics Inc. Topical formulations for treating skin conditions

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5489426A (en) * 1980-07-01 1996-02-06 L'oreal Cosmetic composition based on an aqueous dispersion of small lipid spheres
US5439672A (en) * 1980-07-01 1995-08-08 L'oreal Cosmetic composition based on an aqueous dispersion of small lipid spheres
SE9704031D0 (en) * 1997-11-05 1997-11-05 Astra Ab Novel formulation
US9012477B2 (en) 2009-01-06 2015-04-21 Nuvo Research Inc. Method of treating neuropathic pain
MX2012008168A (en) 2010-01-14 2013-02-07 Nuvo Res Inc Solid-forming local anesthetic formulations for pain control.

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0028110A2 (en) * 1979-10-26 1981-05-06 Smith and Nephew Associated Companies p.l.c. Autoclavable emulsions
EP0028110B1 (en) * 1979-10-26 1984-03-07 Smith and Nephew Associated Companies p.l.c. Autoclavable emulsions
US9308181B2 (en) 2006-03-06 2016-04-12 Nuvo Research Inc. Topical formulations, systems and methods
US9642912B2 (en) 2006-03-06 2017-05-09 Crescita Therapeutics Inc. Topical formulations for treating skin conditions

Also Published As

Publication number Publication date
GB2008946B (en) 1982-06-30
AU524406B2 (en) 1982-09-16
AU4202878A (en) 1979-06-07
SE432192B (en) 1984-03-26
SE7812020L (en) 1979-06-02
DE2851369C2 (en) 1988-04-28
DE2851369A1 (en) 1979-06-07

Similar Documents

Publication Publication Date Title
ES458280A1 (en) Oil-in-water emulsion and process for the preparation thereof
ATE52197T1 (en) OIL-IN-WATER EMULSION.
EP0279641A3 (en) Cosmetic compositions
GB2008946A (en) An emulsion cream composition, process for its preparation, and method of obtaining local anesthesia
KR950703998A (en) 1α, 24- (OH) _2-V.D_3 Emulsion Composition (1α, 24- (OH) _2-V.D_3 EMULSION COMPOSITION)
DE3478029D1 (en) Biopolymer compositions and process for their preparation
KR830005863A (en) Method of producing human chorionic gonadotropin
JPS5227638A (en) Method for stabilization of color developer
PT71408A (en) PROCESS FOR THE PREPARATION OF 1-ALKADIEN-2,4-YL-2-HIDROXYMETHYL-3,4,5-TRIMYDROXYPIPERIDINES WITH EFFECT ON THE CARBOHYDRATES AND / OR FAT CHANGES AND PHARMACEUTICAL AND / OR ANIMAL-SPECIFIC PRAPIDATES CONTAINING THOSE COMPOUNDS
JPS5221006A (en) Oil and fat composition
KR910021361A (en) Anti-ulcer substance
KR850700108A (en) Anti-tumor pharmaceutical composition and preparation method thereof
DE3562562D1 (en) Method and apparatus for obtaining a mixture of substances having low boiling points
JPS5251755A (en) Agents for treating excreta
KR880012226A (en) External agent
JPS5211371A (en) Oil atomizing process and the device
JPS52100463A (en) Gamma-lactone and method of preparing same
JPS5241915A (en) Compressor
ES398351A1 (en) A method for producing a bronzing composition. (Machine-translation by Google Translate, not legally binding)
JPS5233981A (en) Process for preparing emulsions
ES2068361T3 (en) PROCEDURE FOR THE PREPARATION OF (PIRIDIL-3) -2-TETRAHIDROTIOPIRANOCARBOTIOAMIDA-2-OXIDOS-1- (1R, 2R), LOS (PIRIDIL-3) -2-TETRAHIDROTIOPIRANOCARBOTIOAMIDA-2-OXIDOS-1- (1R, 2R) OBTAINED AND THE PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM.
JPS53145927A (en) Emulsion for hair treatment
KR890003290A (en) Manufacturing method of pickles
JPS5238485A (en) Emulsifier for silicone oil
JPS5228467A (en) Evaporation and concentration apparatus

Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19921130