GB1491776A - Thiadiazoles - Google Patents
ThiadiazolesInfo
- Publication number
- GB1491776A GB1491776A GB3829575A GB3829575A GB1491776A GB 1491776 A GB1491776 A GB 1491776A GB 3829575 A GB3829575 A GB 3829575A GB 3829575 A GB3829575 A GB 3829575A GB 1491776 A GB1491776 A GB 1491776A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- thiadiazoles
- sept
- dimethylsulphamoylphenylacethydrazide
- anticonvulsants
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
- C07D285/125—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1491776 Thiadiazoles PFIZER Ltd 8 Sept 1976 [18 Sept 1975] 38295/75 Heading C2C Thiadiazoles are prepared by the following route: (R = C 1-6 alkyl or alkoxy, C 3-6 cycloalkyl, phenoxy or phenyl (C 1-6 alkyl) in which the ring may be substituted by F, Cl, Br, CF 3 or SO 2 N (C 1-4 alkyl)2), optionally followed by conversion to an alkali metal salt. The preparation of the thione starting materials and 3-chloro, 4-fluoro and 4-dimethylsulphamoylphenylacethydrazide is described. The above compounds are cerebral vasodilators, and some of them are anticonvulsants. They may be administered in the form of pharmaceutical preparations containing them in association with a carrier.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB3829575A GB1491776A (en) | 1976-09-08 | 1976-09-08 | Thiadiazoles |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB3829575A GB1491776A (en) | 1976-09-08 | 1976-09-08 | Thiadiazoles |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1491776A true GB1491776A (en) | 1977-11-16 |
Family
ID=10402524
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB3829575A Expired GB1491776A (en) | 1976-09-08 | 1976-09-08 | Thiadiazoles |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB1491776A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1105120A2 (en) * | 1998-08-20 | 2001-06-13 | Agouron Pharmaceuticals, Inc. | NON-PEPTIDE GnRH AGENTS, METHODS AND INTERMEDIATES FOR THEIR PREPARATION |
US7101878B1 (en) | 1998-08-20 | 2006-09-05 | Agouron Pharmaceuticals, Inc. | Non-peptide GNRH agents, methods and intermediates for their preparation |
-
1976
- 1976-09-08 GB GB3829575A patent/GB1491776A/en not_active Expired
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1105120A2 (en) * | 1998-08-20 | 2001-06-13 | Agouron Pharmaceuticals, Inc. | NON-PEPTIDE GnRH AGENTS, METHODS AND INTERMEDIATES FOR THEIR PREPARATION |
EP1105120A4 (en) * | 1998-08-20 | 2001-12-19 | Agouron Pharma | NON-PEPTIDE GnRH AGENTS, METHODS AND INTERMEDIATES FOR THEIR PREPARATION |
US7101878B1 (en) | 1998-08-20 | 2006-09-05 | Agouron Pharmaceuticals, Inc. | Non-peptide GNRH agents, methods and intermediates for their preparation |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PCNP | Patent ceased through non-payment of renewal fee |