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GB1491776A - Thiadiazoles - Google Patents

Thiadiazoles

Info

Publication number
GB1491776A
GB1491776A GB3829575A GB3829575A GB1491776A GB 1491776 A GB1491776 A GB 1491776A GB 3829575 A GB3829575 A GB 3829575A GB 3829575 A GB3829575 A GB 3829575A GB 1491776 A GB1491776 A GB 1491776A
Authority
GB
United Kingdom
Prior art keywords
alkyl
thiadiazoles
sept
dimethylsulphamoylphenylacethydrazide
anticonvulsants
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3829575A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Ltd
Original Assignee
Pfizer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Ltd filed Critical Pfizer Ltd
Priority to GB3829575A priority Critical patent/GB1491776A/en
Publication of GB1491776A publication Critical patent/GB1491776A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D285/00Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01Five-membered rings
    • C07D285/02Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/121,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
    • C07D285/1251,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1491776 Thiadiazoles PFIZER Ltd 8 Sept 1976 [18 Sept 1975] 38295/75 Heading C2C Thiadiazoles are prepared by the following route: (R = C 1-6 alkyl or alkoxy, C 3-6 cycloalkyl, phenoxy or phenyl (C 1-6 alkyl) in which the ring may be substituted by F, Cl, Br, CF 3 or SO 2 N (C 1-4 alkyl)2), optionally followed by conversion to an alkali metal salt. The preparation of the thione starting materials and 3-chloro, 4-fluoro and 4-dimethylsulphamoylphenylacethydrazide is described. The above compounds are cerebral vasodilators, and some of them are anticonvulsants. They may be administered in the form of pharmaceutical preparations containing them in association with a carrier.
GB3829575A 1976-09-08 1976-09-08 Thiadiazoles Expired GB1491776A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB3829575A GB1491776A (en) 1976-09-08 1976-09-08 Thiadiazoles

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3829575A GB1491776A (en) 1976-09-08 1976-09-08 Thiadiazoles

Publications (1)

Publication Number Publication Date
GB1491776A true GB1491776A (en) 1977-11-16

Family

ID=10402524

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3829575A Expired GB1491776A (en) 1976-09-08 1976-09-08 Thiadiazoles

Country Status (1)

Country Link
GB (1) GB1491776A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1105120A2 (en) * 1998-08-20 2001-06-13 Agouron Pharmaceuticals, Inc. NON-PEPTIDE GnRH AGENTS, METHODS AND INTERMEDIATES FOR THEIR PREPARATION
US7101878B1 (en) 1998-08-20 2006-09-05 Agouron Pharmaceuticals, Inc. Non-peptide GNRH agents, methods and intermediates for their preparation

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1105120A2 (en) * 1998-08-20 2001-06-13 Agouron Pharmaceuticals, Inc. NON-PEPTIDE GnRH AGENTS, METHODS AND INTERMEDIATES FOR THEIR PREPARATION
EP1105120A4 (en) * 1998-08-20 2001-12-19 Agouron Pharma NON-PEPTIDE GnRH AGENTS, METHODS AND INTERMEDIATES FOR THEIR PREPARATION
US7101878B1 (en) 1998-08-20 2006-09-05 Agouron Pharmaceuticals, Inc. Non-peptide GNRH agents, methods and intermediates for their preparation

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee