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FR2374042A1 - Nouveau medicament immunostimulant et son procede de preparation - Google Patents

Nouveau medicament immunostimulant et son procede de preparation

Info

Publication number
FR2374042A1
FR2374042A1 FR7616937A FR7616937A FR2374042A1 FR 2374042 A1 FR2374042 A1 FR 2374042A1 FR 7616937 A FR7616937 A FR 7616937A FR 7616937 A FR7616937 A FR 7616937A FR 2374042 A1 FR2374042 A1 FR 2374042A1
Authority
FR
France
Prior art keywords
preparation
medicinal product
immunostimulant
new
new immunostimulant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7616937A
Other languages
English (en)
Other versions
FR2374042B1 (fr
Inventor
Gerard Ayme
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut Merieux SA
Original Assignee
Institut Merieux SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR7616937A priority Critical patent/FR2374042A1/fr
Application filed by Institut Merieux SA filed Critical Institut Merieux SA
Priority to DE2725204A priority patent/DE2725204C2/de
Priority to NL7706174A priority patent/NL7706174A/xx
Priority to GB23738/77A priority patent/GB1583889A/en
Priority to BE178163A priority patent/BE855357A/fr
Priority to CA279,825A priority patent/CA1091582A/fr
Priority to US05/804,150 priority patent/US4182751A/en
Publication of FR2374042A1 publication Critical patent/FR2374042A1/fr
Priority to US06/071,591 priority patent/US4337243A/en
Application granted granted Critical
Publication of FR2374042B1 publication Critical patent/FR2374042B1/fr
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/04Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/062Ascomycota
    • A61K36/064Saccharomycetales, e.g. baker's yeast
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55583Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55588Adjuvants of undefined constitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55588Adjuvants of undefined constitution
    • A61K2039/55594Adjuvants of undefined constitution from bacteria
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Médicament stimulant de l'immunité et son procédé de préparation. Il comporte l'extrait phénolosoluble avec une fraction de cet extrait, des bactéries, levures ou protozoaires. Il est utilisable soit seul, soit associé à d'autres agents actifs dans un domaine de lutte contre les agents infectieux ou pour augmenter le niveau de résistance des défenses immunitaires.
FR7616937A 1976-06-04 1976-06-04 Nouveau medicament immunostimulant et son procede de preparation Granted FR2374042A1 (fr)

Priority Applications (8)

Application Number Priority Date Filing Date Title
FR7616937A FR2374042A1 (fr) 1976-06-04 1976-06-04 Nouveau medicament immunostimulant et son procede de preparation
NL7706174A NL7706174A (nl) 1976-06-04 1977-06-03 Immuno stimulerend geneesmiddel alsmede werkwijze voor het bereiden ervan.
GB23738/77A GB1583889A (en) 1976-06-04 1977-06-03 Immuno-stimulant medicament and process for its preparation
BE178163A BE855357A (fr) 1976-06-04 1977-06-03 Nouveau medicament immunostimulant et son procede de preparation
DE2725204A DE2725204C2 (de) 1976-06-04 1977-06-03 Verfahren zum Herstellen eines die unspezifische Immunität stimulierenden löslichen Mikroorganismenextrakts und diesem enthaltendes Arzneimittel
CA279,825A CA1091582A (fr) 1976-06-04 1977-06-03 Medicament immunostimulant et son procede de preparation
US05/804,150 US4182751A (en) 1976-06-04 1977-06-06 New immunostimulant medicament and process of preparing same
US06/071,591 US4337243A (en) 1976-06-04 1979-08-30 Immunostimulant medicament and process of preparing same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7616937A FR2374042A1 (fr) 1976-06-04 1976-06-04 Nouveau medicament immunostimulant et son procede de preparation

Publications (2)

Publication Number Publication Date
FR2374042A1 true FR2374042A1 (fr) 1978-07-13
FR2374042B1 FR2374042B1 (fr) 1980-04-30

Family

ID=9174007

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7616937A Granted FR2374042A1 (fr) 1976-06-04 1976-06-04 Nouveau medicament immunostimulant et son procede de preparation

Country Status (7)

Country Link
US (2) US4182751A (fr)
BE (1) BE855357A (fr)
CA (1) CA1091582A (fr)
DE (1) DE2725204C2 (fr)
FR (1) FR2374042A1 (fr)
GB (1) GB1583889A (fr)
NL (1) NL7706174A (fr)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2447193A1 (fr) * 1979-01-25 1980-08-22 Unicler Utilisation de pichia ou d'extraits de pichia, comme medicament.
EP0018245A1 (fr) * 1979-03-22 1980-10-29 Roussel-Uclaf Nouveaux dérivés stéroides 7-alkylés, leur procédé de préparation, leur application comme médicament et les compositions pharmaceutiques les renfermant
FR2477416A1 (fr) * 1980-03-10 1981-09-11 Unicler Utilisation de hansenula ou d'extraits de hansenula, comme medicament
FR2480604A1 (fr) * 1980-04-22 1981-10-23 Pasteur Institut Fractions nouvelles extraites de bacteries aerobies, douees de proprietes antitumorales, antibacteriennes et inductrices d'interferon et leur procede de preparation
FR2502496A2 (fr) * 1981-03-30 1982-10-01 Pasteur Institut Fractions nouvelles extraites de bacteries aerobies, douees de proprietes antitumorales, antibacteriennes et inductrices d'interferon, et leur procede de preparation
US4479935A (en) * 1980-04-22 1984-10-30 Institut Pasteur Fractions extracted from aerobic bacteria, endowed with antitumoral, antibacterial and interferon inducing properties, and process for their preparation

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK138379A (da) * 1979-04-04 1980-10-05 Nordisk Droge & Kemikalie Vaccine imod pleuropneumonia (ondartet lungesyge) hos svin dens anvendelse samt fremgangsmaade og substat til dyrkning specielt aerob fermentering af mikroorganismen haemophilus pleuropneumoniae
EP0039325A1 (fr) * 1979-10-19 1981-11-11 ROMANO, Amalia Remede pour le traitement des infections virales de l'oeil et d'autres organes
JPS56135159A (en) 1980-03-26 1981-10-22 Fujirebio Inc Immunological diagnosis method
EP0196530A3 (fr) * 1985-03-26 1989-03-22 CTA Finanz AG Agent et procédé pour augmenter la croissance, optimiser la fécondité et stimuler le système immunitaire chez les humains et les animaux
WO1986006279A1 (fr) * 1985-04-30 1986-11-06 Scripps Clinic And Research Foundation Proteine de phase aigue modulant l'activite endotoxique de lipopolysaccharides, compositions et procedes
US4681761A (en) * 1985-10-24 1987-07-21 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University Major iron-regulated protein of Neisseria gonorrhoeae and its use as vaccine
DE3728367C1 (de) * 1987-08-25 1988-09-01 Burkhard Steglich Mittel zur Immunisierung des menschlichen Koerpers bei HIV-Infektionen
US5223491A (en) * 1989-11-09 1993-06-29 Donzis Byron A Method for revitalizing skin by applying topically water insoluble glucan
EP0595209A3 (en) * 1992-10-23 1996-07-17 R I T A Corp An Illinois Corp Cosmetic composition
US5853738A (en) * 1995-10-30 1998-12-29 Dynagen, Inc. Methods for treatment of human immunodeficiency virus infection with pseudomonas phosphoaminolipid extract
US5851534A (en) * 1996-05-03 1998-12-22 Dynagen, Inc. Methods for prevention and/or treatment of neutropenia
EP0971721A1 (fr) * 1997-04-02 2000-01-19 Bioniche Inc. Utilisation d'extrait de paroi cellulaire bacterienne afin de prevenir, traiter ou eliminer une protozoose ou une maladie parasitaire
US6183756B1 (en) 1997-05-01 2001-02-06 Dynagen, Inc. Methods for prevention and/or treatment of thrombocytopenia
ATE227996T1 (de) 1997-08-05 2002-12-15 Bioniche Life Sciences Inc Zusammensetzung und verfahren zur regulierung von zellproliferation und zelltod
AU785212B2 (en) * 1999-12-13 2006-11-09 Bioniche Life Sciences Inc. Therapeutically useful synthetic oligonucleotides
WO2001047561A1 (fr) * 1999-12-28 2001-07-05 Bioniche Life Sciences Inc. L'acide hyaluronique dans le traitement du cancer
US7491517B2 (en) * 2006-07-19 2009-02-17 Jeeri R Reddy Method of producing meningococcal meningitis vaccine for Neisseria meningitidis serotypes A,C,Y, and W-135
CN104370997B (zh) * 2014-09-24 2018-07-31 陈辉 去除生物制品中细菌内毒素的试剂盒、方法及其生物制品的制备方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1621118A (en) * 1925-11-04 1927-03-15 Winford P Larson Modified bacteria and toxins, immunizing serums and method of producing them
US1621119A (en) * 1926-01-27 1927-03-15 Winford P Larson Scarlet fever antigen
US2020647A (en) * 1933-06-07 1935-11-12 Hunwicke Roderick Francis Method of manufacturing bacterial solutions
NL63957C (fr) * 1946-01-03
US3148120A (en) * 1952-01-24 1964-09-08 Wander Ag Dr A Hot aqueous phenol extraction of gramnegative bacterial lipopolysaccharides
GB725938A (en) * 1952-01-24 1955-03-16 Wander A G A Method of preparing substantially protein-free polysaccharides from micro-organisms
DE1175389B (de) * 1958-07-26 1964-08-06 Wander Ag Dr A Verfahren zur Herstellung stabiler, waessriger Lipoid-Dispersionen
GB1056839A (en) * 1963-09-19 1967-02-01 Johnson & Johnson Brucella antigen
GB1073694A (en) * 1965-05-24 1967-06-28 Twyford Lab Ltd Preparation of bacterial lipopolysaccharides
US3483290A (en) * 1967-10-24 1969-12-09 Carter Wallace Bacterial fractions
US3636192A (en) * 1970-01-13 1972-01-18 Us Army Meningococcal polysaccharide vaccines
US3859434A (en) * 1973-01-08 1975-01-07 Canadian Patents Dev Meningococcal antigens
CA1020460A (fr) * 1973-02-23 1977-11-08 Wellcome Foundation Limited (The) Separation du glycopeptide immunostimulant des bacteries
FR2269961B1 (fr) * 1974-05-06 1978-03-24 Anvar

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2447193A1 (fr) * 1979-01-25 1980-08-22 Unicler Utilisation de pichia ou d'extraits de pichia, comme medicament.
EP0015175A1 (fr) * 1979-01-25 1980-09-03 Univablot Médicament constitué de Pichia ou d'extraits de Pichia
EP0018245A1 (fr) * 1979-03-22 1980-10-29 Roussel-Uclaf Nouveaux dérivés stéroides 7-alkylés, leur procédé de préparation, leur application comme médicament et les compositions pharmaceutiques les renfermant
EP0018245B1 (fr) * 1979-03-22 1982-06-02 Roussel-Uclaf Nouveaux dérivés stéroides 7-alkylés, leur procédé de préparation, leur application comme médicament et les compositions pharmaceutiques les renfermant
FR2477416A1 (fr) * 1980-03-10 1981-09-11 Unicler Utilisation de hansenula ou d'extraits de hansenula, comme medicament
EP0035937A1 (fr) * 1980-03-10 1981-09-16 Univablot Utilisation de Hansenula ou d'extraits de Hansenula, comme médicament
FR2480604A1 (fr) * 1980-04-22 1981-10-23 Pasteur Institut Fractions nouvelles extraites de bacteries aerobies, douees de proprietes antitumorales, antibacteriennes et inductrices d'interferon et leur procede de preparation
US4479935A (en) * 1980-04-22 1984-10-30 Institut Pasteur Fractions extracted from aerobic bacteria, endowed with antitumoral, antibacterial and interferon inducing properties, and process for their preparation
FR2502496A2 (fr) * 1981-03-30 1982-10-01 Pasteur Institut Fractions nouvelles extraites de bacteries aerobies, douees de proprietes antitumorales, antibacteriennes et inductrices d'interferon, et leur procede de preparation

Also Published As

Publication number Publication date
NL7706174A (nl) 1977-12-06
US4337243A (en) 1982-06-29
US4182751A (en) 1980-01-08
FR2374042B1 (fr) 1980-04-30
GB1583889A (en) 1981-02-04
BE855357A (fr) 1977-12-05
DE2725204C2 (de) 1982-03-04
DE2725204A1 (de) 1977-12-22
CA1091582A (fr) 1980-12-16

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