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FR2358394A1 - Nouveaux esters de l'hydroxysuccinimide, des procedes pour leur fabrication et leur utilisation - Google Patents

Nouveaux esters de l'hydroxysuccinimide, des procedes pour leur fabrication et leur utilisation

Info

Publication number
FR2358394A1
FR2358394A1 FR7721728A FR7721728A FR2358394A1 FR 2358394 A1 FR2358394 A1 FR 2358394A1 FR 7721728 A FR7721728 A FR 7721728A FR 7721728 A FR7721728 A FR 7721728A FR 2358394 A1 FR2358394 A1 FR 2358394A1
Authority
FR
France
Prior art keywords
hydroxysuccinimide
manufacture
methods
new esters
esters
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7721728A
Other languages
English (en)
Other versions
FR2358394B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of FR2358394A1 publication Critical patent/FR2358394A1/fr
Application granted granted Critical
Publication of FR2358394B1 publication Critical patent/FR2358394B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F20/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride, ester, amide, imide or nitrile thereof
    • C08F20/02—Monocarboxylic acids having less than ten carbon atoms, Derivatives thereof
    • C08F20/10—Esters
    • C08F20/34—Esters containing nitrogen, e.g. N,N-dimethylaminoethyl (meth)acrylate
    • C08F20/36—Esters containing nitrogen, e.g. N,N-dimethylaminoethyl (meth)acrylate containing oxygen in addition to the carboxy oxygen, e.g. 2-N-morpholinoethyl (meth)acrylate or 2-isocyanatoethyl (meth)acrylate

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Pyrrole Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

L'invention concerne de nouveaux dérivés esters de l'hydroxysuccinimide, leur préparation et leur utilisation. Ces dérivés répondent à la formule générale I :
FR7721728A 1976-07-14 1977-07-13 Nouveaux esters de l'hydroxysuccinimide, des procedes pour leur fabrication et leur utilisation Granted FR2358394A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2631656A DE2631656C2 (de) 1976-07-14 1976-07-14 Verwendung eines Hydroxysuccinimidoester-Derivats zur Bindung von biologisch aktiven Proteinen aneinander und/oder an flüssige oder feste Trägerstoffe

Publications (2)

Publication Number Publication Date
FR2358394A1 true FR2358394A1 (fr) 1978-02-10
FR2358394B1 FR2358394B1 (fr) 1980-02-15

Family

ID=5983006

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7721728A Granted FR2358394A1 (fr) 1976-07-14 1977-07-13 Nouveaux esters de l'hydroxysuccinimide, des procedes pour leur fabrication et leur utilisation

Country Status (11)

Country Link
US (2) US4155914A (fr)
JP (1) JPS6014028B2 (fr)
AT (1) AT360981B (fr)
DE (1) DE2631656C2 (fr)
DK (1) DK319277A (fr)
FR (1) FR2358394A1 (fr)
GB (1) GB1523711A (fr)
HU (1) HU175883B (fr)
IT (1) IT1080882B (fr)
NL (1) NL168220C (fr)
SE (1) SE424319B (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2574075A1 (fr) * 1984-12-04 1986-06-06 Poudres & Explosifs Ste Nale Procede de synthese d'esters actifs d'acides carboxyliques, nouveaux carbonates alpha-halogenes utiles pour cette synthese et leur mode d'obtention
WO2001018080A1 (fr) * 1999-09-08 2001-03-15 School Of Pharmacy, University Of London Polymeres de poids moleculaire uniforme
WO2007022780A1 (fr) * 2005-08-26 2007-03-01 Novo Nordisk A/S Procede de modification de systeme macromoleculaire

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55145665A (en) * 1979-05-02 1980-11-13 Haruo Ogura Agent for forming active ester of amino acid
US4487715A (en) * 1982-07-09 1984-12-11 The Regents Of The University Of California Method of conjugating oligopeptides
JPS6169759A (ja) * 1984-09-14 1986-04-10 Agency Of Ind Science & Technol タンパク質の架橋反応用修飾剤及びそれを用いる方法
US4643991A (en) * 1984-12-18 1987-02-17 The University Of Kentucky Research Foundation Peptide elastase inhibitors and methods
JPH0527613Y2 (fr) * 1988-04-25 1993-07-14
US5122614A (en) * 1989-04-19 1992-06-16 Enzon, Inc. Active carbonates of polyalkylene oxides for modification of polypeptides
ES2247656T3 (es) * 1989-04-19 2006-03-01 Enzon, Inc. Un proceso para formar un polipeptido modificado que comprende un polipeptido y un oxido de polialquileno.
US5324844A (en) * 1989-04-19 1994-06-28 Enzon, Inc. Active carbonates of polyalkylene oxides for modification of polypeptides
DE3924705A1 (de) * 1989-07-26 1991-01-31 Boehringer Mannheim Gmbh Heterobifunktionelle verbindungen
US5672662A (en) * 1995-07-07 1997-09-30 Shearwater Polymers, Inc. Poly(ethylene glycol) and related polymers monosubstituted with propionic or butanoic acids and functional derivatives thereof for biotechnical applications
US6284246B1 (en) 1997-07-30 2001-09-04 The Procter & Gamble Co. Modified polypeptides with high activity and reduced allergenicity
WO1999049056A1 (fr) 1998-03-26 1999-09-30 The Procter & Gamble Company Variants de serine-proteases ayant des substitutions d'acides amines
US6908757B1 (en) 1998-03-26 2005-06-21 The Procter & Gamble Company Serine protease variants having amino acid deletions and substitutions
US6495136B1 (en) 1998-03-26 2002-12-17 The Procter & Gamble Company Proteases having modified amino acid sequences conjugated to addition moieties
US6946128B1 (en) 1999-07-22 2005-09-20 The Procter & Gamble Company Protease conjugates having sterically protected epitope regions
AU6085800A (en) 1999-07-22 2001-02-13 Procter & Gamble Company, The Subtilisin protease variants having amino acid substitutions in defined epitope regions
CA2379729A1 (fr) 1999-07-22 2001-02-01 The Procter & Gamble Company Conjugues de protease comprenant des sites clip proteges steriquement
CA2379712A1 (fr) 1999-07-22 2001-02-01 The Procter & Gamble Company Variants de protease subtilisine possedant des suppressions et des substitutions d'acides amines dans certaines regions de sites antigeniques
ATE412684T1 (de) 2002-09-09 2008-11-15 Nektar Therapeutics Al Corp Verfahren zur herstellung von wasserlöslichen polymerderivaten mit terminalen carboxylgruppen
US7361767B2 (en) * 2003-11-14 2008-04-22 3M Innovative Properties Company N-sulfonyldicarboximide containing tethering compounds
US7423155B2 (en) * 2003-11-14 2008-09-09 3M Innovative Properties Company N-sulfonyldicarboximide containing tethering compounds
ES2720078T3 (es) * 2004-01-21 2019-07-17 Nektar Therapeutics Método para preparar polímeros terminados en ácido propiónico
US7544755B2 (en) 2005-09-30 2009-06-09 3M Innovative Properties Company Crosslinked polymers with amine binding groups
US7544756B2 (en) * 2005-09-30 2009-06-09 3M Innovative Properties Company Crosslinked polymers with amine binding groups
EP2271602A4 (fr) 2008-04-01 2013-03-06 Univ Georgia State Res Found Colonnes monolithiques à base de tensioactif, leurs procédés de fabrication, et leurs procédés d utilisation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2260185C3 (de) * 1971-06-09 1979-06-13 Boehringer Mannheim Gmbh, 6800 Mannheim Trägergebundenes Protein und Verfahren zu seiner Herstellung
US3978079A (en) * 1972-02-04 1976-08-31 American Cyanamid Company Chemiluminescence
DE2346937A1 (de) * 1973-09-18 1975-04-03 Bayer Ag N'-(aminoacylaminophenyl)-acetamidine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
US3940420A (en) * 1974-07-15 1976-02-24 Pierce Chemical Company Compound, dithiobis-(succinimidyl propionate)
US3996268A (en) * 1974-09-03 1976-12-07 The Regents Of The University Of California Cross-linking reagent for insulin synthesis

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2574075A1 (fr) * 1984-12-04 1986-06-06 Poudres & Explosifs Ste Nale Procede de synthese d'esters actifs d'acides carboxyliques, nouveaux carbonates alpha-halogenes utiles pour cette synthese et leur mode d'obtention
EP0185578A1 (fr) * 1984-12-04 1986-06-25 Societe Nationale Des Poudres Et Explosifs Procédé de synthèse d'esters actifs d'acides carboxyliques, carbonates alpha-halogénés utiles pour cette synthèse et leur mode d'obtention
WO2001018080A1 (fr) * 1999-09-08 2001-03-15 School Of Pharmacy, University Of London Polymeres de poids moleculaire uniforme
WO2007022780A1 (fr) * 2005-08-26 2007-03-01 Novo Nordisk A/S Procede de modification de systeme macromoleculaire
EP2045282A1 (fr) * 2005-08-26 2009-04-08 Novo Nordisk A/S Méthode de modification d'un polymère
US7897698B2 (en) 2005-08-26 2011-03-01 Novo Nordisk A/S Method of modifying a macromolecular system

Also Published As

Publication number Publication date
IT1080882B (it) 1985-05-16
FR2358394B1 (fr) 1980-02-15
NL168220B (nl) 1981-10-16
SE7707734L (sv) 1978-01-15
DE2631656A1 (de) 1978-01-19
AT360981B (de) 1981-02-10
ATA376577A (de) 1980-07-15
GB1523711A (en) 1978-09-06
NL168220C (nl) 1982-03-16
SE424319B (sv) 1982-07-12
NL7706944A (nl) 1978-01-17
HU175883B (en) 1980-11-28
JPS539762A (en) 1978-01-28
DK319277A (da) 1978-01-15
US4155914A (en) 1979-05-22
DE2631656C2 (de) 1983-02-10
JPS6014028B2 (ja) 1985-04-11
US4248786A (en) 1981-02-03

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Legal Events

Date Code Title Description
ST Notification of lapse