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FR2340310A1 - Hydrazinophtalazines substituees, leur preparation et compositions pharmaceutiques les contenant - Google Patents

Hydrazinophtalazines substituees, leur preparation et compositions pharmaceutiques les contenant

Info

Publication number
FR2340310A1
FR2340310A1 FR7703442A FR7703442A FR2340310A1 FR 2340310 A1 FR2340310 A1 FR 2340310A1 FR 7703442 A FR7703442 A FR 7703442A FR 7703442 A FR7703442 A FR 7703442A FR 2340310 A1 FR2340310 A1 FR 2340310A1
Authority
FR
France
Prior art keywords
hydrazinophtalazines
substituted
preparation
pharmaceutical compositions
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7703442A
Other languages
English (en)
Other versions
FR2340310B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Smith Kline and French Laboratories Ltd
GlaxoSmithKline LLC
Original Assignee
Smith Kline and French Laboratories Ltd
GlaxoSmithKline LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline and French Laboratories Ltd, GlaxoSmithKline LLC filed Critical Smith Kline and French Laboratories Ltd
Publication of FR2340310A1 publication Critical patent/FR2340310A1/fr
Application granted granted Critical
Publication of FR2340310B1 publication Critical patent/FR2340310B1/fr
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30Phthalazines
    • C07D237/34Phthalazines with nitrogen atoms directly attached to carbon atoms of the nitrogen-containing ring, e.g. hydrazine radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30Phthalazines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30Phthalazines
    • C07D237/32Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FR7703442A 1976-02-09 1977-02-08 Hydrazinophtalazines substituees, leur preparation et compositions pharmaceutiques les contenant Granted FR2340310A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB4896/76A GB1567907A (en) 1976-02-09 1976-02-09 (3-amino-2-hydroxypropoxy)-1-hydrazonophthalazines and pharmaceutical compositions containing them

Publications (2)

Publication Number Publication Date
FR2340310A1 true FR2340310A1 (fr) 1977-09-02
FR2340310B1 FR2340310B1 (fr) 1980-03-07

Family

ID=9785918

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7703442A Granted FR2340310A1 (fr) 1976-02-09 1977-02-08 Hydrazinophtalazines substituees, leur preparation et compositions pharmaceutiques les contenant

Country Status (6)

Country Link
US (1) US4093725A (fr)
JP (1) JPS5297986A (fr)
BE (1) BE851237A (fr)
DE (1) DE2705414A1 (fr)
FR (1) FR2340310A1 (fr)
GB (1) GB1567907A (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4442094A (en) * 1980-12-23 1984-04-10 Merck & Co., Inc. (3-Aralkylamino-2-or-propoxy)heterocyclic compounds
US4331679A (en) * 1980-12-23 1982-05-25 Merck Sharp & Dohme (I.A.) Corp. (3-Aralkylamino-2-or-propoxy) heterocyclic compounds
US4349673A (en) * 1980-12-23 1982-09-14 Merck & Co., Inc. Benzoxazines
US4656168A (en) * 1980-12-23 1987-04-07 Merck & Co., Inc. (3-aralkylamino-2-or-propoxy)heterocyclic compounds in method of effecting bronchodilation
DE4029807A1 (de) * 1990-09-20 1992-03-26 Bayer Ag 4-amino-3-hydroxy-phthalid, sowie ein verfahren zu seiner herstellung
DE4426373A1 (de) * 1994-07-26 1996-02-01 Bayer Ag 3-Substituierte Chinolin-5-carbonsäurederivate und Verfahren zu ihrer Herstellung
WO2004050657A2 (fr) * 2002-11-27 2004-06-17 Artesian Therapeutics, Inc. Composes presentant une activite mixte d'inhibition de la pde et d'antagoniste ou d'agoniste partiel ?eta-adrenergique pour traiter l'insuffisance cardiaque

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4011321A (en) * 1973-12-19 1977-03-08 Smith Kline & French Laboratories Limited Pharmaceutical compositions and methods of inhibiting β-adrenergic receptors

Also Published As

Publication number Publication date
FR2340310B1 (fr) 1980-03-07
GB1567907A (en) 1980-05-21
DE2705414A1 (de) 1977-08-11
US4093725A (en) 1978-06-06
JPS5297986A (en) 1977-08-17
BE851237A (fr) 1977-08-09

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Legal Events

Date Code Title Description
ST Notification of lapse