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FR2298318A1 - Procede pour preparer une composition pharmaceutique liquide a liberation reglee du principe acti - Google Patents

Procede pour preparer une composition pharmaceutique liquide a liberation reglee du principe acti

Info

Publication number
FR2298318A1
FR2298318A1 FR7602016A FR7602016A FR2298318A1 FR 2298318 A1 FR2298318 A1 FR 2298318A1 FR 7602016 A FR7602016 A FR 7602016A FR 7602016 A FR7602016 A FR 7602016A FR 2298318 A1 FR2298318 A1 FR 2298318A1
Authority
FR
France
Prior art keywords
acti
preparing
principle
pharmaceutical composition
liquid pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7602016A
Other languages
English (en)
Other versions
FR2298318B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Seiyaku Co Ltd
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Publication of FR2298318A1 publication Critical patent/FR2298318A1/fr
Application granted granted Critical
Publication of FR2298318B1 publication Critical patent/FR2298318B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
    • A61K9/1278—Post-loading, e.g. by ion or pH gradient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR7602016A 1975-01-27 1976-01-26 Procede pour preparer une composition pharmaceutique liquide a liberation reglee du principe acti Granted FR2298318A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP50011751A JPS5186117A (en) 1975-01-27 1975-01-27 Johoseibiryushiseizainoseiho

Publications (2)

Publication Number Publication Date
FR2298318A1 true FR2298318A1 (fr) 1976-08-20
FR2298318B1 FR2298318B1 (fr) 1978-12-08

Family

ID=11786697

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7602016A Granted FR2298318A1 (fr) 1975-01-27 1976-01-26 Procede pour preparer une composition pharmaceutique liquide a liberation reglee du principe acti

Country Status (5)

Country Link
US (1) US4016100A (fr)
JP (1) JPS5186117A (fr)
DE (1) DE2601207C3 (fr)
FR (1) FR2298318A1 (fr)
GB (1) GB1487989A (fr)

Cited By (13)

* Cited by examiner, † Cited by third party
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FR2399241A1 (fr) * 1977-08-05 1979-03-02 Battelle Memorial Institute Procede de deshydratation d'une dispersion colloidale de liposomes
FR2416008A1 (fr) * 1978-02-02 1979-08-31 Oreal Lyophilisats de liposomes
EP0004223A1 (fr) * 1978-02-24 1979-09-19 PAPAHADJOPOULOS, Demetrios P. Procédé de fabrication de capsules lipidiques renfermant un matériau biologiquement actif, produits obtenus par ce procédé ainsi que leur utilisation
FR2441385A1 (fr) * 1978-11-17 1980-06-13 Serono Ist Farm Procede de preparation extemporanee de liposomes et liposomes ainsi obtenus
EP0021337A2 (fr) * 1979-06-22 1981-01-07 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Préparations pour l'administration parentérale de médicaments liposolubles
EP0036676A1 (fr) * 1978-03-24 1981-09-30 The Regents Of The University Of California Procédé de préparation de liposomes de taille identique et les liposomes ainsi obtenus
EP0043327A1 (fr) * 1980-07-01 1982-01-06 L'oreal Procédé d'obtention de dispersions stables dans une phase aqueuse d'au moins une phase liquide non miscible à l'eau et dispersions correspondantes
EP0065292A2 (fr) * 1981-05-15 1982-11-24 Klaus Prof. Dr. Gersonde Procédé de stockage de vésicules phospholipidiques unilamellaires
US4529561A (en) * 1978-03-24 1985-07-16 The Regents Of The University Of California Method for producing liposomes in selected size range
EP0191824A1 (fr) * 1984-08-08 1986-08-27 Liposome Co Inc Encapsulement d'agents antineoplastiques dans des liposomes.
WO1987005803A1 (fr) * 1986-04-01 1987-10-08 Aktiebolaget Draco COMPOSITIONS DE LIPOSOMES ET SUBSTANCES ACTIVES beta2-RECEPTRICES
WO1992010166A1 (fr) * 1990-12-11 1992-06-25 Sintetica S.A. Procede de production de liposomes a capacite accrue de piegeage des substances etrangeres a encapsuler
US5736155A (en) * 1984-08-08 1998-04-07 The Liposome Company, Inc. Encapsulation of antineoplastic agents in liposomes

Families Citing this family (144)

* Cited by examiner, † Cited by third party
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US4086257A (en) * 1976-10-12 1978-04-25 Sears Barry D Phosphatidyl quaternary ammonium compounds
USRE31609E (en) * 1976-10-12 1984-06-19 Lipid Specialties, Inc. Method of preparing a controlled-release pharmaceutical preparation, and resulting composition
GB1575343A (en) * 1977-05-10 1980-09-17 Ici Ltd Method for preparing liposome compositions containing biologically active compounds
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US4356167A (en) * 1978-01-27 1982-10-26 Sandoz, Inc. Liposome drug delivery systems
GB2026340B (en) * 1978-07-03 1982-12-22 Ash P Stabilising microvesicles
GB2046092B (en) * 1979-03-05 1983-11-02 Toyama Chemical Co Ltd Pharmaceutical composition containing a lysophospholid and a phospholipid
DE2914788A1 (de) * 1979-04-11 1980-10-16 Nattermann A & Cie Parenteral applizierbare, stabile arzneimittelloesungen mit entzuendungshemmender wirkung
DE2914789A1 (de) * 1979-04-11 1980-10-16 Nattermann A & Cie Injizierbare arzneimittel mit entzuendungshemmender wirkung
JPS55153713A (en) * 1979-05-02 1980-11-29 Kureha Chem Ind Co Ltd Pharmaceutical preparation of ribosome containing active substance
US4261975A (en) * 1979-09-19 1981-04-14 Merck & Co., Inc. Viral liposome particle
US4341215A (en) * 1980-09-04 1982-07-27 Tampax Incorporated Absorbent device
JPS62682Y2 (fr) * 1980-11-05 1987-01-09
JPS5782310A (en) * 1980-11-11 1982-05-22 Tanabe Seiyaku Co Ltd Production of liposome preparation
JPS57109835U (fr) * 1980-12-26 1982-07-07
JPS62684Y2 (fr) * 1980-12-30 1987-01-09
JPS5850917Y2 (ja) * 1981-04-24 1983-11-19 大正製薬株式会社 揮発性液剤分与器
US4426330A (en) * 1981-07-20 1984-01-17 Lipid Specialties, Inc. Synthetic phospholipid compounds
US4534899A (en) * 1981-07-20 1985-08-13 Lipid Specialties, Inc. Synthetic phospholipid compounds
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DE3365744D1 (en) * 1982-01-22 1986-10-09 Fisons Plc Liposome and sodium cromoglycate compositions, and methods for their preparation
US4917897A (en) * 1982-01-22 1990-04-17 Fisons Plc Pharmaceutical compositions
US4452747A (en) * 1982-03-22 1984-06-05 Klaus Gersonde Method of and arrangement for producing lipid vesicles
US4485054A (en) * 1982-10-04 1984-11-27 Lipoderm Pharmaceuticals Limited Method of encapsulating biologically active materials in multilamellar lipid vesicles (MLV)
FR2534487B1 (fr) * 1982-10-15 1988-06-10 Dior Christian Parfums Procede d'homogeneisation de dispersions de phases lamellaires lipidiques hydratees, et suspensions obtenues par ce procede
JPS5979137U (ja) * 1982-11-18 1984-05-29 株式会社ソ−ラ− 芳香液容器の蒸散量調節蓋
US4515736A (en) * 1983-05-12 1985-05-07 The Regents Of The University Of California Method for encapsulating materials into liposomes
US4725442A (en) * 1983-06-17 1988-02-16 Haynes Duncan H Microdroplets of water-insoluble drugs and injectable formulations containing same
US4532089A (en) * 1984-01-14 1985-07-30 Northwestern University Method of preparing giant size liposomes
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US4880635B1 (en) * 1984-08-08 1996-07-02 Liposome Company Dehydrated liposomes
US5077056A (en) * 1984-08-08 1991-12-31 The Liposome Company, Inc. Encapsulation of antineoplastic agents in liposomes
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US4622188A (en) * 1984-12-21 1986-11-11 E. I. Du Pont De Nemours And Company Method for manufacturing liposomes
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US4776991A (en) * 1986-08-29 1988-10-11 The United States Of America As Represented By The Secretary Of The Navy Scaled-up production of liposome-encapsulated hemoglobin
US4911929A (en) * 1986-08-29 1990-03-27 The United States Of America As Represented By The Secretary Of The Navy Blood substitute comprising liposome-encapsulated hemoglobin
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US4963362A (en) * 1987-08-07 1990-10-16 Regents Of The University Of Minnesota Freeze-dried liposome mixture containing cyclosporin
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US3056728A (en) * 1958-10-14 1962-10-02 Ohtaki Shinshiro Process for manufacturing powdered preparations containing fat-soluble vitamins, essential oils, and mixtures thereof
US3780195A (en) * 1969-10-22 1973-12-18 Balchem Corp Encapsulation process

Cited By (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2399241A1 (fr) * 1977-08-05 1979-03-02 Battelle Memorial Institute Procede de deshydratation d'une dispersion colloidale de liposomes
FR2416008A1 (fr) * 1978-02-02 1979-08-31 Oreal Lyophilisats de liposomes
US4247411A (en) * 1978-02-02 1981-01-27 L'oreal Storage stability of aqueous dispersions of spherules
EP0004223A1 (fr) * 1978-02-24 1979-09-19 PAPAHADJOPOULOS, Demetrios P. Procédé de fabrication de capsules lipidiques renfermant un matériau biologiquement actif, produits obtenus par ce procédé ainsi que leur utilisation
FR2418023A1 (fr) * 1978-02-24 1979-09-21 Papahadjopoulos Demetrios Procede de fabrication de capsules lipidiques renfermant un materiau biologiquement actif et capsules ainsi obtenues
US4529561A (en) * 1978-03-24 1985-07-16 The Regents Of The University Of California Method for producing liposomes in selected size range
EP0036676A1 (fr) * 1978-03-24 1981-09-30 The Regents Of The University Of California Procédé de préparation de liposomes de taille identique et les liposomes ainsi obtenus
FR2441385A1 (fr) * 1978-11-17 1980-06-13 Serono Ist Farm Procede de preparation extemporanee de liposomes et liposomes ainsi obtenus
EP0021337A2 (fr) * 1979-06-22 1981-01-07 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Préparations pour l'administration parentérale de médicaments liposolubles
EP0021337A3 (en) * 1979-06-22 1981-04-22 F. Hoffmann-La Roche & Co. Aktiengesellschaft Preparations for parenteral administration of fat-soluble drugs
US5055228A (en) * 1980-07-01 1991-10-08 L'oreal Process for the preparation of stable dispersions of at least one water-immiscible liquid phase in an aqueous phase
EP0043327A1 (fr) * 1980-07-01 1982-01-06 L'oreal Procédé d'obtention de dispersions stables dans une phase aqueuse d'au moins une phase liquide non miscible à l'eau et dispersions correspondantes
US5154854A (en) * 1980-07-01 1992-10-13 L'oreal Process for the preparation of stable dispersions of at least one water-immiscible liquid phase in an aqueous phase
EP0065292A3 (en) * 1981-05-15 1983-05-25 Klaus Prof. Dr. Gersonde Process for preparing storage-stable lipid vesicles, application of the process, and lipid vesicles prepared according to the process
EP0065292A2 (fr) * 1981-05-15 1982-11-24 Klaus Prof. Dr. Gersonde Procédé de stockage de vésicules phospholipidiques unilamellaires
EP0191824A1 (fr) * 1984-08-08 1986-08-27 Liposome Co Inc Encapsulement d'agents antineoplastiques dans des liposomes.
EP0191824B1 (fr) * 1984-08-08 1993-10-27 The Liposome Company, Inc. Encapsulement d'agents antineoplastiques dans des liposomes
US5736155A (en) * 1984-08-08 1998-04-07 The Liposome Company, Inc. Encapsulation of antineoplastic agents in liposomes
WO1987005803A1 (fr) * 1986-04-01 1987-10-08 Aktiebolaget Draco COMPOSITIONS DE LIPOSOMES ET SUBSTANCES ACTIVES beta2-RECEPTRICES
WO1992010166A1 (fr) * 1990-12-11 1992-06-25 Sintetica S.A. Procede de production de liposomes a capacite accrue de piegeage des substances etrangeres a encapsuler

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FR2298318B1 (fr) 1978-12-08
JPS5186117A (en) 1976-07-28
DE2601207B2 (de) 1979-10-25
US4016100A (en) 1977-04-05
JPS558488B2 (fr) 1980-03-04
DE2601207A1 (de) 1976-07-29
DE2601207C3 (de) 1980-07-10
GB1487989A (en) 1977-10-05

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