FI853174L - Bicykliska foereningar. - Google Patents
Bicykliska foereningar.Info
- Publication number
- FI853174L FI853174L FI853174A FI853174A FI853174L FI 853174 L FI853174 L FI 853174L FI 853174 A FI853174 A FI 853174A FI 853174 A FI853174 A FI 853174A FI 853174 L FI853174 L FI 853174L
- Authority
- FI
- Finland
- Prior art keywords
- foereningar
- bicycle
- bicycle foereningar
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/04—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB848421493A GB8421493D0 (en) | 1984-08-24 | 1984-08-24 | Bicyclic compounds |
GB858513541A GB8513541D0 (en) | 1984-08-24 | 1985-05-29 | Bicyclic compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
FI853174A0 FI853174A0 (fi) | 1985-08-19 |
FI853174L true FI853174L (fi) | 1986-02-25 |
Family
ID=26288155
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI853174A FI853174L (fi) | 1984-08-24 | 1985-08-19 | Bicykliska foereningar. |
Country Status (14)
Country | Link |
---|---|
US (4) | US4692438A (fi) |
EP (1) | EP0172552A3 (fi) |
AU (1) | AU583843B2 (fi) |
CS (1) | CS255893B2 (fi) |
DK (1) | DK384385A (fi) |
ES (3) | ES8700258A1 (fi) |
FI (1) | FI853174L (fi) |
HU (1) | HU193446B (fi) |
IL (1) | IL76133A (fi) |
MC (1) | MC1694A1 (fi) |
NO (1) | NO161914C (fi) |
NZ (1) | NZ213130A (fi) |
PH (1) | PH21749A (fi) |
PT (1) | PT81015B (fi) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4692438A (en) * | 1984-08-24 | 1987-09-08 | Hoffmann-La Roche Inc. | Pyridazo-diazepines, diazocines, and -triazepines having anti-hypertensive activity |
ZW11586A1 (en) * | 1985-07-01 | 1987-12-30 | Hoffmann La Roche | Bicyclic compounds |
GB8629875D0 (en) * | 1986-12-15 | 1987-01-28 | Hoffmann La Roche | Pyridazodiazepine derivatives |
US5430145A (en) * | 1990-10-18 | 1995-07-04 | Merrell Dow Pharmaceuticals Inc. | Mercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ace |
US5308841A (en) * | 1990-12-21 | 1994-05-03 | Merrell Dow Pharmaceuticals Inc. | Amino and nitro containing tricyclic compounds useful as inhibitors of ACE |
DE69220744T2 (de) * | 1991-09-27 | 1997-11-13 | Merrell Pharma Inc | 2-Substituierte Indan-2-Mercaptoacetylamid-Verbindungen mit Enkephalinase und ACE-Hemmwirkung |
US5455242A (en) * | 1991-09-27 | 1995-10-03 | Merrell Dow Pharmaceuticals Inc. | Carboxyalkyl tricyclic derivatives useful as inhibitors of enkephalinase and ace |
US5457196A (en) * | 1991-09-27 | 1995-10-10 | Merrell Dow Pharmaceuticals Inc. | 2-substituted indane-2-carboxyalkyl derivatives useful as inhibitors of enkephalinase and ACE |
ES2117123T3 (es) * | 1992-02-14 | 1998-08-01 | Merrell Pharma Inc | Derivados de aminocetilmercaptoacetilamida utilizados como inhibidores de la encefalinasa y del enzima de conversion de angiotensina. |
DK0640086T3 (da) * | 1992-05-15 | 1999-12-06 | Merrell Pharma Inc | Mercaptoacetylamido-pyridazo[1,2-a][1,2]diazepin-derivateranvendelige som enkephalinase- og ACE-inhibitorer |
US5420271A (en) * | 1992-08-24 | 1995-05-30 | Merrell Dow Pharmaceuticals, Inc. | 2-substituted indane-2-mercaptoacetylamide tricyclic derivatives useful as inhibitors of enkephalinase |
WO1994010193A1 (en) * | 1992-10-30 | 1994-05-11 | Merrell Dow Pharmaceuticals Inc. | Novel mercaptoacetylamide bicyclic lactam derivatives useful as inhibitors of enkephalinase and ace |
WO1994022440A1 (en) * | 1993-03-29 | 1994-10-13 | Smithkline Beecham Corporation | Bicyclic compounds which inhibit platelet aggregation |
DK0745080T3 (da) * | 1994-02-14 | 1999-09-27 | Merrell Pharma Inc | Nye mercaptoacetylamiddisulfidderivater, der er anvendelige som inhibitorer af enkephalinase og ACE. |
US5530013A (en) * | 1994-02-14 | 1996-06-25 | American Home Products Corporation | Venlafaxine in the inducement of cognition enhancement |
AU689192B2 (en) * | 1994-02-14 | 1998-03-26 | Merrell Pharmaceuticals Inc. | Novel 2-substituted indane-2-mercaptoacetylamide disulfide derivatives useful as inhibitors of enkephalinase and ace |
HUT74385A (en) * | 1994-02-14 | 1996-12-30 | Merrell Pharma Inc | Novel mercaptoacetylamido 1,3,4,5-tetrahydro-benzo[c]azepin-3-one disulfide derivatives useful as inhibitors of enkephalinase and ace |
DE69524064T2 (de) * | 1994-02-14 | 2002-07-11 | Merrell Pharmaceuticals Inc., Cincinnati | Indan-2-mercaptoacetylamid disulfidderivate als enkephalinase inhibitoren |
US5484783A (en) * | 1994-03-24 | 1996-01-16 | Merrell Dow Pharmaceuticals Inc. | Hypocholesterolemic, antiatherosclerotic and hypotriglyceridemic mercaptoacetylamide and benzazapine derivatives |
HUT75160A (en) * | 1994-03-24 | 1997-04-28 | Merrell Pharma Inc | Hypocholesterolemic, antiatherosclerotic and hypotriglyceridemic aminoacetylmercapto derivatives |
CA2184692C (en) * | 1994-03-24 | 2001-01-02 | Gary A. Flynn | Hypocholesterolemic, antiatherosclerotic and hypotriglyceridemic mercaptoacetylamide disulfide derivatives |
US6559304B1 (en) | 1998-08-19 | 2003-05-06 | Vertex Pharmaceuticals Incorporated | Method for synthesizing caspase inhibitors |
US6703500B2 (en) | 1998-08-19 | 2004-03-09 | Vertex Pharmaceuticals, Incorporated | Method of preparing bicyclic intermediates from piperazic acid or an ester thereof useful in the manufacture of caspase inhibitors |
US6177565B1 (en) * | 1998-08-19 | 2001-01-23 | Vertex Pharmaceuticals Inc. | Process for synthesizing piperazic acid |
NZ520998A (en) | 2000-05-04 | 2004-11-26 | Vertex Pharma | Asymmetric synthesis of piperazic acid and derivatives thereof |
GB0119305D0 (en) | 2001-04-12 | 2001-10-03 | Aventis Pharma Gmbh | Mercaptoacetylamide derivatives,a process for their preparation and their use |
EA016837B1 (ru) * | 2008-07-25 | 2012-07-30 | Чулуун Энхболд | Способ обогащения и транспортировки твердого топлива на тепловую электростанцию |
CA2784131C (en) * | 2009-12-16 | 2017-07-11 | Hetero Research Foundation | Polymorphs of darunavir |
PT2571355T (pt) | 2010-05-20 | 2016-10-17 | Hetero Research Foundation | Sal de cloridrato cristalino de darunavir |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4308094A (en) * | 1977-02-02 | 1981-12-29 | Sanyo Electric Co., Ltd. | Diaphragm for speaker and method of producing same |
IL60617A0 (en) * | 1979-07-23 | 1980-09-16 | Sparamedica Ag | Triazolopyridazine derivative,their preparation and pharmaceutical compositions containing them |
DE3062972D1 (en) * | 1979-09-19 | 1983-06-09 | Hoffmann La Roche | Pyridazopyridazine derivatives, processes for their preparation and pharmaceutical compositions containing these pyridazopyridazine derivatives |
EP0042100A1 (de) * | 1980-06-13 | 1981-12-23 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | Pyrazolopyridazin-Derivate, Zwischenprodukte und Verfahren zu deren Herstellung, sowie diese enthaltende Arzneimittel |
GB2128984B (en) * | 1982-05-12 | 1985-05-22 | Hoffmann La Roche | Diaza-bicyclic compounds |
US4692438A (en) * | 1984-08-24 | 1987-09-08 | Hoffmann-La Roche Inc. | Pyridazo-diazepines, diazocines, and -triazepines having anti-hypertensive activity |
-
1985
- 1985-08-12 US US06/764,372 patent/US4692438A/en not_active Expired - Fee Related
- 1985-08-15 CS CS855928A patent/CS255893B2/cs unknown
- 1985-08-16 NZ NZ213130A patent/NZ213130A/en unknown
- 1985-08-19 EP EP85110370A patent/EP0172552A3/de not_active Withdrawn
- 1985-08-19 AU AU46415/85A patent/AU583843B2/en not_active Ceased
- 1985-08-19 FI FI853174A patent/FI853174L/fi not_active Application Discontinuation
- 1985-08-19 IL IL76133A patent/IL76133A/xx unknown
- 1985-08-21 HU HU853187A patent/HU193446B/hu not_active IP Right Cessation
- 1985-08-21 PH PH32671A patent/PH21749A/en unknown
- 1985-08-21 MC MC851791A patent/MC1694A1/xx unknown
- 1985-08-23 NO NO853336A patent/NO161914C/no unknown
- 1985-08-23 PT PT81015A patent/PT81015B/pt unknown
- 1985-08-23 DK DK384385A patent/DK384385A/da not_active Application Discontinuation
- 1985-08-23 ES ES546360A patent/ES8700258A1/es not_active Expired
-
1986
- 1986-02-17 ES ES552397A patent/ES8705443A1/es not_active Expired
- 1986-02-17 ES ES552398A patent/ES8705444A1/es not_active Expired
-
1987
- 1987-05-11 US US07/048,172 patent/US4785093A/en not_active Expired - Fee Related
- 1987-06-15 US US07/062,033 patent/US4762924A/en not_active Expired - Fee Related
-
1988
- 1988-07-12 US US07/217,805 patent/US4826980A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ES546360A0 (es) | 1986-10-01 |
DK384385A (da) | 1986-02-25 |
ES552397A0 (es) | 1987-05-01 |
NO853336L (no) | 1986-02-25 |
PH21749A (en) | 1988-02-18 |
US4762924A (en) | 1988-08-09 |
US4692438A (en) | 1987-09-08 |
HU193446B (en) | 1987-10-28 |
ES552398A0 (es) | 1987-05-01 |
MC1694A1 (fr) | 1986-07-18 |
FI853174A0 (fi) | 1985-08-19 |
CS592885A2 (en) | 1987-07-16 |
EP0172552A3 (de) | 1989-01-11 |
ES8700258A1 (es) | 1986-10-01 |
US4785093A (en) | 1988-11-15 |
HUT38644A (en) | 1986-06-30 |
AU4641585A (en) | 1986-02-27 |
US4826980A (en) | 1989-05-02 |
IL76133A (en) | 1989-12-15 |
CS255893B2 (en) | 1988-03-15 |
IL76133A0 (en) | 1985-12-31 |
ES8705444A1 (es) | 1987-05-01 |
PT81015B (en) | 1987-08-24 |
NO161914C (no) | 1989-10-11 |
NO161914B (no) | 1989-07-03 |
NZ213130A (en) | 1988-05-30 |
ES8705443A1 (es) | 1987-05-01 |
AU583843B2 (en) | 1989-05-11 |
PT81015A (en) | 1985-09-01 |
DK384385D0 (da) | 1985-08-23 |
EP0172552A2 (de) | 1986-02-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD | Application lapsed |
Owner name: F. HOFFMANN-LA ROCHE AG |