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ES8609344A1 - Cefalosporinas - Google Patents

Cefalosporinas

Info

Publication number
ES8609344A1
ES8609344A1 ES543301A ES543301A ES8609344A1 ES 8609344 A1 ES8609344 A1 ES 8609344A1 ES 543301 A ES543301 A ES 543301A ES 543301 A ES543301 A ES 543301A ES 8609344 A1 ES8609344 A1 ES 8609344A1
Authority
ES
Spain
Prior art keywords
image
carbon atoms
optionally substituted
cephalosporins
hydrocarbyl radical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES543301A
Other languages
English (en)
Other versions
ES543301A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of ES543301A0 publication Critical patent/ES543301A0/es
Publication of ES8609344A1 publication Critical patent/ES8609344A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/48—Methylene radicals, substituted by hetero rings
    • C07D501/56—Methylene radicals, substituted by hetero rings with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEIDMIENTO PARA LA OBTENCION DE NUEVAS CEFALOSPORINAS DE FORMULA GENERAL (I) Y DE SUS SALES FARMACEUTICAMENTE TOLERABLES. ESTAS NUEVAS CEFALOSPORINAS PUEDEN OBTENERSE HACIENDO REACCIONAR COMPUESTOS DE FORMULA GENERAL (II) CON COMPUESTOS DE FORMULA (III). PARA LA COPULACION DE LOS ACIDOS CARBOXILICOS (II) CON LAS LACTAMAS (III) SE EMPLEAN LOS METODOS USUALES EN LA QUIMICA DE LAS CEFALOSPORINAS O DE LAS PENICILINAS. ES VENTAJOSA LA ACTIVACION DE LOS ACIDOS CARBOXILICOS SIN GRUPO PROTECTOR DE AMINA Y A CONTINUACION COPULACION CON LAS B-LACTAMAS QUE SE DISUELVEN EN FORMA DE SALES CON AMINAS. LAS NUEVAS CEFALOSPORINAS SE EMPLEAN COMO MEDICAMENTOS, ESPECIALMENTE EN LA TERAPIA ANTIBIOTICA, ANTIMICROBIANA AMPLIA Y FUERTE ESPECIALMENTE CONTRA BACTERIAS GRAM-NEGATIVAS Y GRAM-POSITIVAS, TANTO EN MEDICINA COMO EN VETERINARIA.
ES543301A 1984-05-22 1985-05-20 Cefalosporinas Expired ES8609344A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843419013 DE3419013A1 (de) 1984-05-22 1984-05-22 Neue cephalosporine und verfahren zu ihrer herstellung

Publications (2)

Publication Number Publication Date
ES543301A0 ES543301A0 (es) 1986-09-01
ES8609344A1 true ES8609344A1 (es) 1986-09-01

Family

ID=6236534

Family Applications (1)

Application Number Title Priority Date Filing Date
ES543301A Expired ES8609344A1 (es) 1984-05-22 1985-05-20 Cefalosporinas

Country Status (13)

Country Link
US (1) US4686216A (es)
EP (1) EP0162394B1 (es)
JP (1) JPS60255796A (es)
KR (1) KR850008491A (es)
AT (1) ATE54148T1 (es)
AU (1) AU584336B2 (es)
CA (1) CA1284993C (es)
DE (2) DE3419013A1 (es)
DK (1) DK225985A (es)
ES (1) ES8609344A1 (es)
GR (1) GR851223B (es)
PT (1) PT80491B (es)
ZA (1) ZA853830B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4880795A (en) * 1984-05-22 1989-11-14 Bayer Aktiengesellschaft Cephalosporins
US4680409A (en) * 1984-10-09 1987-07-14 E. R. Squibb & Sons, Inc. Hydrazide containing derivatives of 2-amino-4-thiazole-acetic acid
DE3506159A1 (de) * 1985-02-22 1986-08-28 Bayer Ag, 5090 Leverkusen Neue cephalosporine, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
DE3789466T2 (de) * 1986-03-17 1994-07-28 Fujisawa Pharmaceutical Co 3,7-Disubstituierte-3-Cephemverbindungen und Verfahren zu ihrer Herstellung.
PH25965A (en) * 1988-06-06 1992-01-13 Fujisawa Pharmaceutical Co New cephem compounds which have antimicrobial activities
US5244890A (en) * 1988-06-06 1993-09-14 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
US5262374A (en) * 1989-11-17 1993-11-16 Oki Electric Industry Co., Ltd. Thermoreversible recording medium, apparatus utilizing the same and method for fabricating the same
JP4658806B2 (ja) * 2003-09-09 2011-03-23 日本化学工業株式会社 ３−クロロメチル−３−セフェム誘導体の製造方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1591439A (en) * 1976-10-01 1981-06-24 Glaxo Operations Ltd 7-syn (oxyimino -acylamido) cephalosporins
GB2115180A (en) * 1981-11-06 1983-09-01 Wainco Prod Ltd Device for feeding films into a processor
CA1213882A (en) * 1982-03-04 1986-11-12 Jun Okumura Cephalosporins
US4525473A (en) * 1983-03-30 1985-06-25 Bristol-Myers Company Cephalosporins
ZA847825B (en) * 1983-10-08 1985-05-29 Hoechst Ag Caphalosporin derivatives and processes for their preparations
DE3409431A1 (de) * 1983-10-08 1985-04-18 Hoechst Ag, 6230 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
DE3419013A1 (de) 1985-11-28
ZA853830B (en) 1986-01-29
DE3578423D1 (de) 1990-08-02
EP0162394A2 (de) 1985-11-27
JPS60255796A (ja) 1985-12-17
AU4256685A (en) 1985-11-28
DK225985A (da) 1985-11-23
PT80491A (en) 1985-06-01
GR851223B (es) 1985-11-25
KR850008491A (ko) 1985-12-18
CA1284993C (en) 1991-06-18
EP0162394B1 (de) 1990-06-27
PT80491B (en) 1987-04-21
DK225985D0 (da) 1985-05-21
ES543301A0 (es) 1986-09-01
ATE54148T1 (de) 1990-07-15
US4686216A (en) 1987-08-11
AU584336B2 (en) 1989-05-25
EP0162394A3 (en) 1986-12-30

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Legal Events

Date Code Title Description
MM4A Patent lapsed

Effective date: 19960506