ES488494A0 - Metodo para producir compuestos de beta-lactama - Google Patents

Metodo para producir compuestos de beta-lactama

Info

Publication number: ES488494A0
Authority: ES; Spain
Prior art keywords: lactama; compounds; producing beta; beta; producing
Prior art date: 1979-02-13
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

ES488494A

Other languages

English (en)

Other versions

ES8101596A1 (es

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Leo Pharma AS

Original Assignee

Leo Pharmaceutical Products Ltd AS

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-02-13

Filing date

1980-02-12

Publication date

1980-12-16

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27449109&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES488494(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1980-02-12 Application filed by Leo Pharmaceutical Products Ltd AS filed Critical Leo Pharmaceutical Products Ltd AS

1980-12-16 Publication of ES488494A0 publication Critical patent/ES488494A0/es

1980-12-16 Publication of ES8101596A1 publication Critical patent/ES8101596A1/es

Status Expired legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)

ES488494A 1979-02-13 1980-02-12 Metodo para producir compuestos de beta-lactama Expired ES8101596A1 (es)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
GB7905020		1979-02-13
GB7921341		1979-06-19
GB7927761		1979-08-09
GB7939473		1979-11-14

Publications (2)

Publication Number	Publication Date
ES488494A0 true ES488494A0 (es)	1980-12-16
ES8101596A1 ES8101596A1 (es)	1980-12-16

Family

ID=27449109

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES488494A Expired ES8101596A1 (es)	1979-02-13	1980-02-12	Metodo para producir compuestos de beta-lactama

Country Status (33)

Country	Link
US (2)	US4840944A (es)
AR (1)	AR230286A1 (es)
AT (1)	AT368507B (es)
AU (1)	AU532531B2 (es)
CA (1)	CA1230113A (es)
CH (2)	CH646436A5 (es)
CS (1)	CS234015B2 (es)
CY (1)	CY1205A (es)
DD (1)	DD149529A5 (es)
DE (2)	DE3050895C2 (es)
DK (1)	DK160943C (es)
ES (1)	ES8101596A1 (es)
FI (2)	FI73220C (es)
FR (1)	FR2449089A1 (es)
GB (2)	GB2044255B (es)
GR (1)	GR74091B (es)
HK (1)	HK5684A (es)
HU (1)	HU182604B (es)
IE (2)	IE49881B1 (es)
IL (1)	IL59203A (es)
IT (1)	IT1147306B (es)
KE (1)	KE3309A (es)
LU (1)	LU82164A1 (es)
MA (1)	MA18731A1 (es)
MY (1)	MY8500006A (es)
NL (1)	NL8000775A (es)
NZ (1)	NZ192762A (es)
PH (1)	PH16326A (es)
PL (1)	PL125079B1 (es)
PT (1)	PT70805A (es)
SE (2)	SE446186B (es)
SG (1)	SG43783G (es)
YU (1)	YU42659B (es)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE449103B (sv) *	1979-03-05	1987-04-06	Pfizer	Sett att framstella penicillansyra-1,1-dioxid samt estrar derav
US4420426A (en)	1979-03-05	1983-12-13	Pfizer Inc.	6-Alpha-halopenicillanic acid 1,1-dioxides
US4714761A (en) *	1979-03-05	1987-12-22	Pfizer Inc.	6,6-dihalopenicillanic acid 1,1-dioxides and process
US4309347A (en) *	1979-05-16	1982-01-05	Pfizer Inc.	Penicillanoyloxymethyl penicillanate 1,1,1',1'-tetraoxide
US4244951A (en)	1979-05-16	1981-01-13	Pfizer Inc.	Bis-esters of methanediol with penicillins and penicillanic acid 1,1-dioxide
US4364957A (en) *	1979-09-26	1982-12-21	Pfizer Inc.	Bis-esters of alkanediols as antibacterial agents
US4342768A (en)	1979-10-22	1982-08-03	Pfizer Inc.	Bis-esters of 1,1-alkanediols with 6-beta-hydroxymethylpenicillanic acid 1,1-dioxide and beta-lactam antibiotics
US4432970A (en) *	1979-11-23	1984-02-21	Pfizer Inc.	6-beta-Halopenicillanic acid 1,1-dioxides as beta-lactamase inhibitors
US4340539A (en)	1980-01-21	1982-07-20	Bristol-Myers Company	Derivatives of 6-bromo penicillanic acid
ZA81306B (en) *	1980-01-21	1982-02-24	Bristol Myers Co	Chemical compounds
IL61880A (en) *	1980-01-21	1984-11-30	Bristol Myers Co	2beta-chloromethyl-2alpha-methylpenam-3alpha-carboxylic acid sulfone derivatives,their preparation and pharmaceutical compositions containing them
US4488994A (en) *	1980-09-08	1984-12-18	Pfizer Inc.	Bis-esters of methanediol with penicillins and penicillanic acid 1,1-dioxide
IE51516B1 (en) *	1980-10-06	1987-01-07	Leo Pharm Prod Ltd	1,1-dioxapenicillanoyloxymethyl 6-(d-alpha-amino-alpha-phenylacetamido)penicillanate napsylate
IL64009A (en) *	1980-10-31	1984-09-30	Rech Applications Therap	Crystalline 1,1-dioxopenicillanoyloxymethyl 6-(d-alpha-amino-alpha-phenylacetamido)penicillanate tosylate hydrates,their production and pharmaceutical compositions containing them
US4380512A (en) *	1980-12-11	1983-04-19	Bristol-Myers Company	2β-Chloromethyl-2α-methylpenam-3α-carboxylic acid sulfone and salts and esters thereof
US4474698A (en) *	1980-12-11	1984-10-02	Pfizer Inc.	Process for preparing esters of penicillanic acid sulfone
US4376076A (en)	1981-03-23	1983-03-08	Pfizer Inc.	Bis-esters of 1,1-alkanediols with 6-beta-hydroxymethylpenicillanic acid 1,1-dioxide
IN157669B (es) *	1981-03-23	1986-05-17	Pfizer
US4321196A (en)	1981-03-23	1982-03-23	Pfizer Inc.	Bis-esters of methanediol with acetonides of ampicillin or amoxicillin and penicillanic acid 1,1-dioxide
US4393001A (en)	1981-03-23	1983-07-12	Pfizer Inc.	Intermediates for production of 1,1-dioxopenicillanoyloxymethyl 6-(2-amino-2-phenylacetamido)penicillanates
IN159362B (es) *	1981-03-23	1987-05-09	Pfizer
US4381263A (en) *	1981-03-23	1983-04-26	Pfizer Inc.	Process for the preparation of penicillanic acid esters
US4419284A (en)	1981-03-23	1983-12-06	Pfizer Inc.	Preparation of halomethyl esters (and related esters) of penicillanic acid 1,1-dioxide
US4444687A (en) *	1981-06-08	1984-04-24	Bristol-Myers Company	2β-Chloromethyl-2α-methylpenam-3α-carboxylic acid sulfone methylene diol mixed esters
PL136237B1 (en) *	1981-09-09	1986-02-28	Pfizer Inc	Process for preparing novel derivatives of 6'-/2-amino-/4-acyloxyphenyl/acetamido/-penicillanoyloxymethyl penicillanate 1,1-dioxide
US4582829A (en) *	1981-09-09	1986-04-15	Pfizer Inc.	Antibacterial 6'-(2-amino-2-[4-acyloxyphenyl]acetamido)penicillanoyloxymethyl penicillanate 1,1-dioxide compounds
US4540687A (en) *	1981-09-09	1985-09-10	Pfizer Inc.	Antibacterial 6'-(2-amino-2-[4-acyloxyphenyl]acetamido)penicillanoyloxymethyl penicillanate 1,1-dioxide compounds
US4351840A (en) *	1981-09-18	1982-09-28	Pfizer Inc.	Antibacterial esters of resorcinol with ampicillin and penicillanic acid 1,1-dioxide derivatives
US4457924A (en) *	1981-12-22	1984-07-03	Pfizer, Inc.	1,1-Alkanediol dicarboxylate linked antibacterial agents
US4359472A (en)	1981-12-22	1982-11-16	Pfizer Inc.	Bis-hydroxymethyl carbonate bridged antibacterial agents
US4452796A (en) *	1982-06-14	1984-06-05	Pfizer Inc.	6-Aminoalkylpenicillanic acid 1,1-dioxides as beta-lactamase inhibitors
EP0084730A1 (en) *	1982-01-22	1983-08-03	Beecham Group Plc	Esters of penicillin derivatives with beta-lactamase inhibitors, their preparation and their use
US4444686A (en) *	1982-01-25	1984-04-24	Pfizer Inc.	Crystalline penicillin ester intermediate
US4432987A (en) *	1982-04-23	1984-02-21	Pfizer Inc.	Crystalline benzenesulfonate salts of sultamicillin
IT1190897B (it) *	1982-06-29	1988-02-24	Opos Biochimica Srl	Procedimento per la preparazione dell'estere 1-etossicarbonilossietilico dell'acido 6-(d(-)-alfa aminoalfa fenilacetamido)-penicillanico
WO1984001776A1 (en) *	1982-10-26	1984-05-10	Beecham Group Plc	Beta-lactam compounds, preparation and use
US4530792A (en) *	1982-11-01	1985-07-23	Pfizer Inc.	Process and intermediates for preparation of 1,1-dioxopenicillanoyloxymethyl 6-beta-aminopenicillanate
IL67637A0 (en) *	1983-01-07	1983-05-15	Orvet Bv	Preparation of 1'-ethoxycarbonyl-oxyethyl esters of penicillins and novel intermediates
US4868297A (en) *	1982-12-06	1989-09-19	Pfizer Inc.	Process for preparing sultamicillin and analogs
US4462934A (en)	1983-03-31	1984-07-31	Pfizer Inc.	Bis-esters of dicarboxylic acids with amoxicillin and certain hydroxymethylpenicillanate 1,1-dioxides
US4536393A (en) *	1983-06-06	1985-08-20	Pfizer Inc.	6-(Aminomethyl)penicillanic acid 1,1-dioxide esters and intermediates therefor
JPH01139584A (ja) *	1987-11-25	1989-06-01	Yoshitomi Pharmaceut Ind Ltd	ペニシラン酸化合物の製造法
KR910009271B1 (ko) *	1989-06-20	1991-11-08	김영설	1,1-디옥소페닐실라노일 옥시메틸 D-6-[α-(메틸렌아미노)페닐-아세트아미도]-페니실라네이트와 그의 파라-톨루엔술폰산염
US5399678A (en) *	1990-04-13	1995-03-21	Pfizer Inc.	Process for sultamicillin intermediate
ES2161602B1 (es) *	1999-04-08	2003-02-16	Asturpharma S A	Sintesis de 6-(d-alfa-(bencilidenaminofenilacetamido))penicilanato de 1,1-dioxopenicilanoiloximetilo y analogos. nuevos intermedios para la sintesis de sultamicilina.
WO2007004239A1 (en) *	2005-07-06	2007-01-11	Morepen Laboratories Limited	New polymorphic form of sultamicillin tosylate and a process therefor
TR201922977A2 (tr) *	2019-12-31	2021-07-26	T C Erciyes Ueniversitesi	Penisilin türevleri ve bunların sentezlenmesi için yöntem
CN115385934A (zh) *	2022-10-26	2022-11-25	北京纳百生物科技有限公司	一种舒巴坦半抗原及其合成方法和应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1303491A (es) *	1970-03-24	1973-01-17
GB1335718A (en) *	1971-05-05	1973-10-31	Leo Pharm Prod Ltd	Penicillin esters salts thereof and methods for their preparation
US3838152A (en) *	1971-10-07	1974-09-24	American Home Prod	Poly alpha-amino penicillins
GB1467604A (en) *	1974-06-27	1977-03-16	Toyama Chemical Co Ltd	Bis-type penicillins and process for producing the same
GB1573614A (en) *	1976-02-25	1980-08-28	Leo Pharm Prod Ltd	Amidinopenicillanoyloxyalkyl cephalosporanates
GB1578128A (en) *	1976-03-30	1980-11-05	Leo Pharm Prod Ltd	Amidinopenicillanoyloxyalkyl amoxycillinates
GB1579931A (en) *	1976-04-15	1980-11-26	Leo Pharm Prod Ltd	Bis-penicillanoyl-oxy-alkanes
IN149747B (es) *	1977-06-07	1982-04-03	Pfizer
US4197240A (en) *	1977-12-23	1980-04-08	Yeda Research And Development Co. Ltd.	Penicillin derivatives
US4244951A (en) *	1979-05-16	1981-01-13	Pfizer Inc.	Bis-esters of methanediol with penicillins and penicillanic acid 1,1-dioxide

1980
- 1980-01-21 IE IE2654/83A patent/IE49881B1/en unknown
- 1980-01-21 IE IE111/80A patent/IE49880B1/en not_active IP Right Cessation
- 1980-01-23 IL IL59203A patent/IL59203A/xx unknown
- 1980-01-24 US US06/118,063 patent/US4840944A/en not_active Expired - Lifetime
- 1980-01-25 CY CY1205A patent/CY1205A/xx unknown
- 1980-01-25 GB GB8002682A patent/GB2044255B/en not_active Expired
- 1980-01-25 GB GB08221654A patent/GB2108107B/en not_active Expired
- 1980-01-25 PH PH23555A patent/PH16326A/en unknown
- 1980-01-30 NZ NZ192762A patent/NZ192762A/en unknown
- 1980-01-31 AR AR279816A patent/AR230286A1/es active
- 1980-01-31 YU YU244/80A patent/YU42659B/xx unknown
- 1980-02-05 AT AT0061580A patent/AT368507B/de not_active IP Right Cessation
- 1980-02-07 NL NL8000775A patent/NL8000775A/nl not_active Application Discontinuation
- 1980-02-07 CA CA000345227A patent/CA1230113A/en not_active Expired
- 1980-02-08 MA MA18928A patent/MA18731A1/fr unknown
- 1980-02-08 PT PT70805A patent/PT70805A/pt active IP Right Revival
- 1980-02-11 DD DD80218994A patent/DD149529A5/de unknown
- 1980-02-11 CH CH110080A patent/CH646436A5/de not_active IP Right Cessation
- 1980-02-11 FI FI800411A patent/FI73220C/fi not_active IP Right Cessation
- 1980-02-12 SE SE8001099A patent/SE446186B/sv not_active IP Right Cessation
- 1980-02-12 DK DK059480A patent/DK160943C/da not_active IP Right Cessation
- 1980-02-12 CS CS80929A patent/CS234015B2/cs unknown
- 1980-02-12 AU AU55462/80A patent/AU532531B2/en not_active Ceased
- 1980-02-12 IT IT19865/80A patent/IT1147306B/it active Protection Beyond IP Right Term
- 1980-02-12 ES ES488494A patent/ES8101596A1/es not_active Expired
- 1980-02-12 LU LU82164A patent/LU82164A1/fr unknown
- 1980-02-12 DE DE3050895A patent/DE3050895C2/de not_active Expired
- 1980-02-12 HU HU80310A patent/HU182604B/hu unknown
- 1980-02-12 PL PL1980221964A patent/PL125079B1/pl unknown
- 1980-02-12 DE DE3005164A patent/DE3005164C2/de not_active Expired
- 1980-02-12 FR FR8003061A patent/FR2449089A1/fr active Granted
- 1980-02-12 GR GR61189A patent/GR74091B/el unknown
- 1980-12-04 US US06/213,083 patent/US4342772A/en not_active Expired - Lifetime
1983
- 1983-07-21 KE KE3309A patent/KE3309A/xx unknown
- 1983-07-23 SG SG43783A patent/SG43783G/en unknown
- 1983-11-11 CH CH608183A patent/CH645902A5/de not_active IP Right Cessation
1984
- 1984-01-12 HK HK56/84A patent/HK5684A/xx not_active IP Right Cessation
- 1984-09-05 SE SE8404462A patent/SE461913B/sv unknown
1985
- 1985-12-30 MY MY6/85A patent/MY8500006A/xx unknown
1987
- 1987-02-11 FI FI870555A patent/FI76807C/fi not_active IP Right Cessation

Also Published As

Publication number	Publication date
FI76807C (fi)	1988-12-12
US4840944A (en)	1989-06-20
NZ192762A (en)	1984-10-19
AT368507B (de)	1982-10-25
FI800411A (fi)	1980-08-14
AR230286A1 (es)	1984-03-01
CH646436A5 (de)	1984-11-30
MY8500006A (en)	1985-12-31
GB2108107B (en)	1983-09-01
KE3309A (en)	1983-08-19
CY1205A (en)	1983-12-31
NL8000775A (nl)	1980-08-15
DE3005164A1 (de)	1980-08-21
SG43783G (en)	1985-01-11
YU24480A (en)	1983-04-30
SE446186B (sv)	1986-08-18
LU82164A1 (fr)	1980-09-24
FR2449089B1 (es)	1983-06-10
IL59203A (en)	1982-12-31
DD149529A5 (de)	1981-07-15
DK160943C (da)	1991-10-21
PT70805A (en)	1980-03-01
GB2044255B (en)	1983-05-11
CS234015B2 (en)	1985-03-14
IT8019865A0 (it)	1980-02-12
AU532531B2 (en)	1983-10-06
GB2108107A (en)	1983-05-11
FI870555A (fi)	1987-02-11
PL221964A1 (es)	1980-12-01
FI73220C (fi)	1987-09-10
IT1147306B (it)	1986-11-19
MA18731A1 (fr)	1980-10-01
ES8101596A1 (es)	1980-12-16
IE49881B1 (en)	1986-01-08
FI870555A0 (fi)	1987-02-11
ATA61580A (de)	1982-02-15
IL59203A0 (en)	1980-05-30
US4342772A (en)	1982-08-03
GB2044255A (en)	1980-10-15
IE832654L (en)	1980-08-13
DK59480A (da)	1980-08-14
DE3005164C2 (de)	1986-06-26
SE8001099L (sv)	1980-08-14
SE8404462L (sv)	1984-09-05
AU5546280A (en)	1980-08-21
DK160943B (da)	1991-05-06
PH16326A (en)	1983-09-05
FI73220B (fi)	1987-05-29
SE461913B (sv)	1990-04-09
HU182604B (en)	1984-02-28
FR2449089A1 (fr)	1980-09-12
SE8404462D0 (sv)	1984-09-05
FI76807B (fi)	1988-08-31
IE49880B1 (en)	1986-01-08
YU42659B (en)	1988-10-31
CH645902A5 (de)	1984-10-31
GR74091B (es)	1984-06-06
DE3050895C2 (es)	1989-05-03
PL125079B1 (en)	1983-03-31
HK5684A (en)	1984-01-20
CA1230113A (en)	1987-12-08

Publication	Publication Date	Title
ES488494A0 (es)	1980-12-16	Metodo para producir compuestos de beta-lactama
AR230433A1 (es)	1984-04-30	Procedimiento para producir derivados fenetilaminicos sulfamoil sustituidos
MX156153A (es)	1988-07-19	Procedimiento para producir derivados de carboestirilo
ES488744A0 (es)	1981-02-16	Metodo para la fabricacion de compuestos sulfurados
MX6806E (es)	1986-07-30	Procedimiento para producir derivados de carboestirilo
ES492032A0 (es)	1981-04-01	Procedimiento para preparar compuestos de cefem
BR7705098A (pt)	1978-04-04	Processo para obtencao de compostos
MX160826A (es)	1990-05-30	Metodo para producir heteropoli-acidos
AR226036A1 (es)	1982-05-31	Procedimiento para producir nuevos compuestos de beta-lactama
KR850001463A (ko)	1985-03-18	벤조디아제핀 화합물의 제조방법
BR7802464A (pt)	1979-01-16	Processo para desnitrosacao de compostos n-nitrosos
BR8002698A (pt)	1980-12-16	Processos para preparacao de compostos
ES489689A0 (es)	1981-02-16	Procedimiento para preparar compuestos de isotiourea
ES493499A0 (es)	1981-07-01	Procedimiento para preparar compuestos de 3-metilemazetidina
AR226127A1 (es)	1982-05-31	Procedimiento para producir un compuesto de piran-4-ona
ES488493A0 (es)	1980-12-16	Metodo para producir compuestos de b-lactama
ES532486A0 (es)	1985-09-01	Procedimiento para producir derivados de tiatriazina
AR226853A1 (es)	1982-08-31	Metodo para preparar 1,2-dihidro-2-oxo-5-(piridinil)-nicotinonitrilos
AR230629A1 (es)	1984-05-31	Procedimiento para preparar compuestos de dihalogenotriacinil-aminonaftol
BR8107773A (pt)	1982-08-31	Processo para preparar compostos
BR8105908A (pt)	1982-06-08	Processo para preparacao de acetaldeido
ES494019A0 (es)	1981-08-01	Un metodo para la preparacion de nuevos pirimidinoles
ES506012A0 (es)	1983-01-01	Procedimiento para preparar compuestos de halogenotriazinilo
AR226879A1 (es)	1982-08-31	Procedimiento para preparar compuestos de 2-amino-beta-sulfatoetilsulfonilfenol
ES495984A0 (es)	1981-10-01	Procedimiento para preparar compuestos de 6-metileno-morfi- nano

Legal Events

Date	Code	Title	Description
2007-12-01	FD1A	Patent lapsed	Effective date: 20001218