ES385658A1 - Procedimiento para la preparacion de acidos 1-aminoalcan-- 1,1-difosfonicos o de sus sales. - Google Patents
Procedimiento para la preparacion de acidos 1-aminoalcan-- 1,1-difosfonicos o de sus sales.Info
- Publication number
- ES385658A1 ES385658A1 ES385658A ES385658A ES385658A1 ES 385658 A1 ES385658 A1 ES 385658A1 ES 385658 A ES385658 A ES 385658A ES 385658 A ES385658 A ES 385658A ES 385658 A1 ES385658 A1 ES 385658A1
- Authority
- ES
- Spain
- Prior art keywords
- aminoalkane
- hydrogen
- carbon atoms
- group
- diphosphonates
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000002253 acid Substances 0.000 title 1
- 150000007513 acids Chemical class 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 abstract 1
- PHSPJQZRQAJPPF-UHFFFAOYSA-N N-alpha-Methylhistamine Chemical compound CNCCC1=CN=CN1 PHSPJQZRQAJPPF-UHFFFAOYSA-N 0.000 abstract 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 125000005037 alkyl phenyl group Chemical group 0.000 abstract 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- ZRALSGWEFCBTJO-UHFFFAOYSA-O guanidinium Chemical compound NC(N)=[NH2+] ZRALSGWEFCBTJO-UHFFFAOYSA-O 0.000 abstract 1
- 229910001385 heavy metal Inorganic materials 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 150000002762 monocarboxylic acid derivatives Chemical class 0.000 abstract 1
- 125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000003884 phenylalkyl group Chemical group 0.000 abstract 1
- 229910052698 phosphorus Inorganic materials 0.000 abstract 1
- 239000011574 phosphorus Substances 0.000 abstract 1
- -1 piperidino, pyrrolidino Chemical group 0.000 abstract 1
- JUJWROOIHBZHMG-UHFFFAOYSA-O pyridinium Chemical compound C1=CC=[NH+]C=C1 JUJWROOIHBZHMG-UHFFFAOYSA-O 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3839—Polyphosphonic acids
- C07F9/3873—Polyphosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Detergent Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE1958123A DE1958123C3 (de) | 1969-11-19 | 1969-11-19 | Verfahren zur Herstellung von 1 -Aminoalkan-1,1 -diphosphonsäuren oder deren Salzen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES385658A1 true ES385658A1 (es) | 1973-03-16 |
Family
ID=5751538
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES385658A Expired ES385658A1 (es) | 1969-11-19 | 1970-11-18 | Procedimiento para la preparacion de acidos 1-aminoalcan-- 1,1-difosfonicos o de sus sales. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US3846420A (es) |
| JP (1) | JPS4914733B1 (es) |
| BE (1) | BE759160A (es) |
| CH (1) | CH540935A (es) |
| DE (1) | DE1958123C3 (es) |
| ES (1) | ES385658A1 (es) |
| FR (1) | FR2069656A5 (es) |
| GB (1) | GB1267016A (es) |
| NL (1) | NL167700C (es) |
| SE (1) | SE373371B (es) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2316396C3 (de) * | 1973-04-02 | 1975-09-18 | Joh. A. Benckiser Gmbh, 6700 Ludwigshafen | N(1,1-Di-phosphono-äthyl)acetamidin, seine Herste lung und Verwendung zur Steinverhütung |
| DE2343147C2 (de) * | 1973-08-27 | 1982-06-09 | Henkel KGaA, 4000 Düsseldorf | Pyrrolidon-5,5-diphosphonsäuren, deren wasserlösliche Salze, und Verfahren zu ihrer Herstellung |
| DE2343195C2 (de) * | 1973-08-27 | 1981-11-19 | Henkel KGaA, 4000 Düsseldorf | Cyclische Aminophosphonsäuren und Verfahren zu deren Herstellung |
| DE2343196C3 (de) * | 1973-08-27 | 1980-01-10 | Henkel Kgaa, 4000 Duesseldorf | Aiacycloalkan-2^-diphosphonsäuren oder deren wasserlösliche Salze |
| DE2603702C3 (de) * | 1976-01-31 | 1981-04-30 | Joh. A. Benckiser Gmbh, 6700 Ludwigshafen | Verfahren zur Herstellung von N-Acyl-N-alkylaminomethandiphosphonsäure |
| US4163733A (en) * | 1977-10-25 | 1979-08-07 | Buckman Laboratories, Inc. | Synergistic compositions for corrosion and scale control |
| DE2722539C3 (de) * | 1977-05-18 | 1981-11-19 | Joh. A. Benckiser Gmbh, 6700 Ludwigshafen | Verfahren zur Herstellung der N,N-Dimethylaminomethan-diphosphonsäure |
| DE2846835A1 (de) * | 1978-10-27 | 1980-05-08 | Benckiser Knapsack Gmbh | Verfahren zur herstellung von carboxylalkan-aminoalkan-diphosphonsaeuren und -aminoarylalkan-diphosphonsaeuren |
| DE3133308A1 (de) * | 1981-08-22 | 1983-03-17 | Chemische Fabrik Budenheim Rudolf A. Oetker, 6501 Budenheim | Verfahren zur herstellung von n-alkyl-aminomethandiphosphonsaeuren |
| DE3232754A1 (de) * | 1981-08-22 | 1984-03-08 | Chemische Fabrik Budenheim Rudolf A. Oetker, 6501 Budenheim | Verfahren zur herstellung von n-alkyl-aminomethan-diphosphonsaeuren |
| FR2558837B1 (fr) * | 1984-01-26 | 1986-06-27 | Sanofi Sa | Derives de l'acide methylenediphosphonique, procede d'obtention et medicaments antirhumatismaux les contenant |
| IL77243A (en) * | 1984-12-21 | 1996-11-14 | Procter & Gamble | Pharmaceutical compositions containing geminal diphosphonic acid compounds and certain such novel compounds |
| DE3611522A1 (de) * | 1986-04-05 | 1987-10-08 | Henkel Kgaa | Diphosphonylierte oxonitrille, verfahren zu ihrer herstellung und ihre verwendung in mikrobistatischen zusammensetzungen sowie mikrobistatisch wirksame, diphosphonylierte oxonitrile enthaltende zusammensetzungen |
| DE3640938A1 (de) * | 1986-11-29 | 1988-06-01 | Boehringer Mannheim Gmbh | Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindung enthaltende arzneimittel |
| US4868164A (en) * | 1986-12-19 | 1989-09-19 | Norwich Eaton Pharmaceuticals, Inc. | Octahydro-pyridine diphosphonate compounds, pharmaceutical compositions, and methods for treating abnormal calcium and phosphate metabolism |
| IL86951A (en) * | 1987-07-06 | 1996-07-23 | Procter & Gamble Pharma | Methylene phosphonoalkylphosphinates and pharmaceutical preparations containing them |
| US4963681A (en) * | 1987-07-06 | 1990-10-16 | Norwich Eaton Pharmaceuticals, Inc. | Process for synthesis of aminomethylene phosphonoalkylphosphinates |
| DE3724653A1 (de) * | 1987-07-25 | 1989-02-02 | Henkel Kgaa | Olefinische diphosphonsaeuren, verfahren zu ihrer herstellung und ihre verwendung als thresholder sowie komplexierend wirkende, olefinische diphosphonsaeuren enthaltende zusammensetzungen |
| DE3724654A1 (de) * | 1987-07-25 | 1989-02-02 | Henkel Kgaa | Hydroxyacetonitrildiphosphonsaeure, verfahren zu ihrer herstellung und ihre verwendung |
| CA1339805C (en) * | 1988-01-20 | 1998-04-07 | Yasuo Isomura | (cycloalkylamino)methylenebis(phosphonic acid) and medicines containing the same as an active |
| US4933472A (en) * | 1988-04-08 | 1990-06-12 | Yamanouchi Pharmaceutical Co., Ltd. | Substituted aminomethylenebis(phosphonic acid) derivatives |
| US5350743A (en) * | 1991-02-07 | 1994-09-27 | Kaken Pharmaceutical Co., Ltd. | Bisphosphonic acid derivatives, as bone resorption inhibitors |
| DE10151180B4 (de) * | 2001-10-17 | 2010-05-12 | Nowack, Norbert, Prof. Dr.-Ing. | Verfahren und Lösung zur Entschichtung von metallischen Gegenständen mit Nickel-Korrosionsschutzbeschichtung |
| EP1482897A2 (en) * | 2002-02-19 | 2004-12-08 | Ilex Products, Inc. | Aminodiphosphonate apolipoprotein e modulators |
| WO2020070543A1 (en) | 2018-10-03 | 2020-04-09 | Italmatch Chemicals S.P.A. | Process for manufacturing n-alkyl-diphosphonate amino aminoacids |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1202441B (de) * | 1963-03-02 | 1965-10-07 | Therachemie Chem Therapeut | Mittel zur Verminderung der Schaedigung von Haaren beim Bleichen und Faerben |
| DE1302557B (es) * | 1963-04-09 | 1971-08-26 |
-
1969
- 1969-11-19 DE DE1958123A patent/DE1958123C3/de not_active Expired
-
1970
- 1970-10-15 SE SE7013950A patent/SE373371B/xx unknown
- 1970-10-15 NL NL7015156A patent/NL167700C/xx not_active IP Right Cessation
- 1970-11-17 US US00090454A patent/US3846420A/en not_active Expired - Lifetime
- 1970-11-18 CH CH1708670A patent/CH540935A/de not_active IP Right Cessation
- 1970-11-18 GB GB1267016D patent/GB1267016A/en not_active Expired
- 1970-11-18 ES ES385658A patent/ES385658A1/es not_active Expired
- 1970-11-19 FR FR7041475A patent/FR2069656A5/fr not_active Expired
- 1970-11-19 JP JP45101890A patent/JPS4914733B1/ja active Pending
- 1970-11-19 BE BE759160D patent/BE759160A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR2069656A5 (es) | 1971-09-03 |
| NL7015156A (es) | 1971-05-24 |
| JPS4914733B1 (es) | 1974-04-10 |
| DE1958123A1 (de) | 1971-05-19 |
| SE373371B (sv) | 1975-02-03 |
| NL167700B (nl) | 1981-08-17 |
| DE1958123B2 (de) | 1978-02-09 |
| DE1958123C3 (de) | 1978-09-28 |
| BE759160A (fr) | 1971-05-19 |
| CH540935A (de) | 1973-08-31 |
| NL167700C (nl) | 1982-01-18 |
| US3846420A (en) | 1974-11-05 |
| GB1267016A (es) | 1972-03-15 |
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