ES2098739T3 - Composiciones oftalmicas conteniendo una cyclosporin. - Google Patents
Composiciones oftalmicas conteniendo una cyclosporin.Info
- Publication number
- ES2098739T3 ES2098739T3 ES93909919T ES93909919T ES2098739T3 ES 2098739 T3 ES2098739 T3 ES 2098739T3 ES 93909919 T ES93909919 T ES 93909919T ES 93909919 T ES93909919 T ES 93909919T ES 2098739 T3 ES2098739 T3 ES 2098739T3
- Authority
- ES
- Spain
- Prior art keywords
- cyclosporin
- compositions containing
- ophthalmic compositions
- eye
- polyoxyethylene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Ophthalmology & Optometry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Abstract
UNA COMPOSICION OFTALMICA, PARTICULARMENTE EN FORMA DE GOTAS, ADECUADA PARA EL TRATAMIENTO DE ENFERMEDADES DEL OJO Y PARTES CIRCUNDANTES. LA COMPOSICION CONTIENE UNA CICLOSPORINA Y UN SURFACTANTE, SELECCIONADO ENTRE ESTERES ACIDOS GRASOS DE POLIOXIETILENO, ETERES DE ALQUILFENIL POLIOXIETILENO Y ETERES DE ALQUILO POLIOXIETILENO, O MEZCLAS DE LOS MISMOS.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB929210226A GB9210226D0 (en) | 1992-05-13 | 1992-05-13 | Pharmaceutical compositions |
GB929224367A GB9224367D0 (en) | 1992-11-20 | 1992-11-20 | Organic compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2098739T3 true ES2098739T3 (es) | 1997-05-01 |
Family
ID=26300871
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES93909919T Expired - Lifetime ES2098739T3 (es) | 1992-05-13 | 1993-05-07 | Composiciones oftalmicas conteniendo una cyclosporin. |
Country Status (14)
Country | Link |
---|---|
US (2) | US5951971A (es) |
EP (1) | EP0642332B1 (es) |
JP (2) | JP3631490B2 (es) |
KR (1) | KR100344083B1 (es) |
CN (1) | CN1074932C (es) |
AT (1) | ATE147619T1 (es) |
DE (1) | DE69307505T2 (es) |
DK (1) | DK0642332T3 (es) |
ES (1) | ES2098739T3 (es) |
GR (1) | GR3022990T3 (es) |
HK (1) | HK1004520A1 (es) |
SG (1) | SG45449A1 (es) |
TW (1) | TW279801B (es) |
WO (1) | WO1993023010A1 (es) |
Families Citing this family (70)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SG45449A1 (en) * | 1992-05-13 | 1998-01-16 | Sandoz Ltd | Ophthalmic compositions |
US5766629A (en) | 1995-08-25 | 1998-06-16 | Sangstat Medical Corporation | Oral cyclosporin formulations |
US5827822A (en) * | 1996-03-25 | 1998-10-27 | Sangstat Medical Corporation | Cyclosporin a formulations as nanoparticles |
US5834017A (en) * | 1995-08-25 | 1998-11-10 | Sangstat Medical Corporation | Oral cyclopsporin formulations |
US5962019A (en) * | 1995-08-25 | 1999-10-05 | Sangstat Medical Corporation | Oral cyclosporin formulations |
EP0988046B1 (en) | 1997-01-30 | 2004-09-15 | Novartis AG | Oil-free pharmaceutical compositions containing cyclosporin a |
MX9701946A (es) * | 1997-03-14 | 1998-04-30 | Arturo Jimenez Bayardo | Solucion oftalmica transportadora. |
ES2225156T3 (es) | 1999-06-03 | 2005-03-16 | Maxim Pharmaceuticals, Inc. | Composiciones oftalmicas que contienen histamina y usos de las mismas. |
JP4880808B2 (ja) * | 1999-11-15 | 2012-02-22 | 久光製薬株式会社 | 人工涙液型点眼剤組成物 |
TR200302105T4 (tr) | 2000-04-07 | 2004-02-23 | Laboratoire Medidom S. A. | Siklosporin, hiyalüronik asit ve polisorbat içeren göz formülasyonları. |
PT1412384E (pt) | 2001-06-28 | 2008-03-28 | Novo Nordisk As | Formulação estável de glp-1 modificado |
US20030165545A1 (en) * | 2002-01-30 | 2003-09-04 | Allergan, Inc. | Ophthalmic compositions including oil-in-water emulsions, and methods for making and using same |
WO2004096261A1 (es) * | 2003-05-02 | 2004-11-11 | Arturo Jimenez Bayardo | Metodo para preparar una solucion acuosa de ciclosporina-a y solucion acuosa resultante |
CN102940879B (zh) | 2003-06-03 | 2017-06-06 | 诺沃挪第克公司 | 稳定化的药物肽组合物 |
WO2004105790A1 (en) | 2003-06-03 | 2004-12-09 | Novo Nordisk A/S | Stabilized pharmaceutical peptide compositions |
US20050059583A1 (en) | 2003-09-15 | 2005-03-17 | Allergan, Inc. | Methods of providing therapeutic effects using cyclosporin components |
SI3300721T1 (sl) * | 2003-11-20 | 2019-07-31 | Novo Nordisk A/S | Peptidne formulacije, ki vsebujejo propilen glikol in ki so optimalne za proizvodnjo in uporabo v napravah za injiciranje |
US7241674B2 (en) * | 2004-05-13 | 2007-07-10 | Taiwan Semiconductor Manufacturing Co., Ltd. | Method of forming silicided gate structure |
ES2442223T3 (es) | 2004-08-31 | 2014-02-10 | Novo Nordisk A/S | Uso de tris(hidroximetil) aminometano para la estabilización de péptidos, polipéptidos y proteínas |
PL1817048T3 (pl) | 2004-11-12 | 2014-07-31 | Novo Nordisk As | Stabilne preparaty peptydów insulinotropowych |
US7135455B2 (en) * | 2004-11-15 | 2006-11-14 | Allergan, Inc | Methods for the therapeutic use of cyclosporine components |
US7151085B2 (en) | 2004-11-15 | 2006-12-19 | Allergan, Inc. | Therapeutic methods using cyclosporine components |
AU2006235478B2 (en) * | 2005-04-12 | 2011-07-21 | Elan Pharma International Limited | Nanoparticulate and controlled release compositions comprising cyclosporine |
CN101193634A (zh) * | 2005-06-09 | 2008-06-04 | 参天制药株式会社 | 罗氟司特滴眼液 |
US7288520B2 (en) * | 2005-07-13 | 2007-10-30 | Allergan, Inc. | Cyclosporin compositions |
US20070015691A1 (en) | 2005-07-13 | 2007-01-18 | Allergan, Inc. | Cyclosporin compositions |
US20070015693A1 (en) * | 2005-07-13 | 2007-01-18 | Allergan, Inc. | Cyclosporin compositions |
US7202209B2 (en) * | 2005-07-13 | 2007-04-10 | Allergan, Inc. | Cyclosporin compositions |
US7297679B2 (en) | 2005-07-13 | 2007-11-20 | Allergan, Inc. | Cyclosporin compositions |
US7276476B2 (en) * | 2005-07-13 | 2007-10-02 | Allergan, Inc. | Cyclosporin compositions |
US7501393B2 (en) * | 2005-07-27 | 2009-03-10 | Allergan, Inc. | Pharmaceutical compositions comprising cyclosporins |
AU2006304143A1 (en) * | 2005-10-14 | 2007-04-26 | Allergan, Inc. | Prevention and treatment of drug-associated ocular side effects with a cyclosporin |
US9839667B2 (en) | 2005-10-14 | 2017-12-12 | Allergan, Inc. | Prevention and treatment of ocular side effects with a cyclosporin |
US7745400B2 (en) * | 2005-10-14 | 2010-06-29 | Gregg Feinerman | Prevention and treatment of ocular side effects with a cyclosporin |
US20070225217A1 (en) * | 2005-11-09 | 2007-09-27 | Combinatorx, Incorporated | Methods, compositions, and kits for the treatment of medical conditions |
US20080146497A1 (en) * | 2006-07-25 | 2008-06-19 | Graham Richard S | Cyclosporin Compositions |
AU2016203191B2 (en) * | 2006-07-25 | 2018-03-01 | Allergan, Inc. | Cyclosporin compositions |
US9561178B2 (en) * | 2006-07-25 | 2017-02-07 | Allergan, Inc. | Cyclosporin compositions |
CN101896160A (zh) * | 2006-10-17 | 2010-11-24 | 阿勒根公司 | 环胞菌素组合物 |
DE202007008971U1 (de) | 2007-06-27 | 2008-11-06 | Weber, Erhard, Dr. | Abstandshalter aus Schaumstoff zur Füllung von Matratzenkernen, Polsterungen und Kissen |
EP2234629A4 (en) * | 2008-01-04 | 2011-05-25 | Alcon Pharmaceuticals Ltd | STABLE AQUEOUS CYCLOSPORIN COMPOSITIONS |
JP5288970B2 (ja) * | 2008-09-26 | 2013-09-11 | シスメックス株式会社 | 血液試料希釈用試薬を用いた平均赤血球容積の測定方法 |
US20100279951A1 (en) * | 2009-05-01 | 2010-11-04 | Aileen Morgan | Method of treating allergic conjunctivitis with cyclosporin compositions |
JP5673531B2 (ja) * | 2009-06-30 | 2015-02-18 | ライオン株式会社 | 眼科用組成物 |
US8492422B2 (en) | 2010-09-16 | 2013-07-23 | Allergan, Inc. | Ester pro-drugs of [3-(1-(1H-imidazol-4-yl)ethyl)-2-methylphenyl] methanol for treating skin diseases and conditions |
WO2012073856A1 (ja) * | 2010-11-29 | 2012-06-07 | 千寿製薬株式会社 | ジフルプレドナートおよびトブラマイシンを含有する水中油型エマルジョン組成物 |
US9018202B2 (en) | 2010-12-03 | 2015-04-28 | Allergan, Inc. | Methods for treating diseases of the retina |
DE102011108948A1 (de) * | 2011-07-29 | 2013-01-31 | Achim Göpferich | Wässrige, kolloidale Lösungen von lipophilen Substanzen,insbesondere Arzneistofflösungen |
WO2013078151A1 (en) | 2011-11-21 | 2013-05-30 | Allergan, Inc. | Pharmaceutical compositions comprising 4-[1-(2,3-dimethylphenyl)ethyl]-3h-imidazole derivatives for treating retinal diseases |
JP6150079B2 (ja) * | 2011-12-16 | 2017-06-21 | アラーガン、インコーポレイテッドAllergan,Incorporated | ポリビニルカプロラクタム−ポリビニルアセテート−ポリエチレングリコールグラフト共重合体を含む眼用組成物 |
US20130197002A1 (en) | 2012-01-30 | 2013-08-01 | Allergan, Inc. | Brimonidine for treating visual disorders mediated by central visual projections from the eye |
FR2988297B1 (fr) * | 2012-03-22 | 2014-03-28 | Thea Lab | Solution ophtalmique aqueuse a base de ciclosporine a sans conservateur |
KR101211902B1 (ko) * | 2012-04-30 | 2012-12-13 | 주식회사 휴온스 | 사이클로스포린 함유 무자극성 나노에멀젼 안약 조성물 |
SI2887923T1 (sl) | 2012-08-24 | 2023-09-29 | Sun Pharmaceutical Industries Limited | Oftalmična formulacija polioksilnega lipida ali polioksilne maščobne kisline in zdravljenje očesnih stanj |
JP6353365B2 (ja) * | 2012-09-27 | 2018-07-04 | 千寿製薬株式会社 | 水性液剤 |
AU2013344497B2 (en) * | 2012-11-19 | 2016-04-14 | Bausch & Lomb Incorporated | Aqueous liquid composition containing 2-amino-3-(4-bromobenzoyl)phenylacetic acid |
BR112015014367B1 (pt) * | 2012-12-19 | 2022-11-22 | Novartis Ag | Composição inibidora de lfa-1, método para estabilizar a dita composição e uso da mesma para tratar uma doença ocular |
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BR112017025631A2 (pt) * | 2015-05-29 | 2018-08-07 | Oculis Ehf | composições oftálmicas aquosas, método de induzir ou aumentar a formação de lágrima, método de formação de aglomerados de ciclosporina a e uso de ciclosporina a |
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WO2017083167A1 (en) | 2015-11-10 | 2017-05-18 | Ocular Technologies Sarl | Topical formulations and uses thereof |
AU2017227585C1 (en) | 2016-02-29 | 2022-05-26 | Sun Pharmaceutical Industries Limited | Topical cyclosporine-containing formulations and uses thereof |
CA3032695C (en) | 2016-08-19 | 2021-11-23 | Akrivista, LLC | Methods of diagnosing and treating dry eye syndrome and compositions for treating a human eye |
ES2965677T3 (es) * | 2016-09-23 | 2024-04-16 | Novaliq Gmbh | Composiciones oftálmicas que comprenden ciclosporina |
US11583496B2 (en) * | 2016-10-12 | 2023-02-21 | PS Therapy Inc. | Drug vehicle compositions and methods of use thereof |
EP3668474A4 (en) | 2017-08-18 | 2021-05-26 | Akrivista, LLC | METHODS OF DIAGNOSIS AND TREATMENT OF DRY EYE SYNDROME AND COMPOSITIONS FOR TREATMENT OF A HUMAN EYE |
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JP2022538659A (ja) * | 2019-07-01 | 2022-09-05 | オキュリス エスエー | 薬剤を含む水性組成物のpHを安定化させるための方法 |
US20230093542A1 (en) | 2020-02-18 | 2023-03-23 | Novo Nordisk A/S | Glp-1 compositions and uses thereof |
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HU205010B (en) | 1987-09-15 | 1992-03-30 | Sandoz Ag | Process for producing pharmaceutical compositions comprising compounds soluble up to 1 per cent and having medical activity |
IL88076A (en) | 1987-10-28 | 1993-01-14 | Nippon Shinyaku Co Ltd | Fat emulsions as drug carriers |
US4914188A (en) | 1987-11-16 | 1990-04-03 | Merck & Co., Inc. | Novel 6-position cyclosporin analogs as non-immunosuppressive antagonists of cyclosporin binding to cyclophilin |
HU203564B (en) * | 1987-12-21 | 1991-08-28 | Sandoz Ag | Process for producing new orthorombos cyclosporin without solvatation |
EP0327280B1 (en) | 1988-01-29 | 1992-03-18 | Sankyo Company Limited | Cyclosporin compositions |
CH679119A5 (es) | 1988-05-13 | 1991-12-31 | Sandoz Ag | |
HU201567B (en) | 1988-07-21 | 1990-11-28 | Gyogyszerkutato Intezet | Process for production of intravenous medical compositions containing cyclosphorin |
US5342625A (en) * | 1988-09-16 | 1994-08-30 | Sandoz Ltd. | Pharmaceutical compositions comprising cyclosporins |
GB2222770B (en) * | 1988-09-16 | 1992-07-29 | Sandoz Ltd | Pharmaceutical compositions containing cyclosporins |
US5338761A (en) | 1988-09-29 | 1994-08-16 | Shiseido Company Ltd. | Emulsified composition |
BE1003578A4 (fr) | 1988-10-26 | 1992-04-28 | Sandoz Sa | Nouvelles compositions ophtalmiques a base d'une cyclosporine. |
JPH0738771B2 (ja) | 1989-01-17 | 1995-05-01 | 花王株式会社 | 液状食用油組成物 |
WO1990008537A1 (en) | 1989-02-06 | 1990-08-09 | Abbott Laboratories | Pharmaceutical compositions for oral administration |
FR2642650B1 (fr) | 1989-02-09 | 1994-12-09 | Sandoz Sa | Nouvelles compositions pharmaceutiques a base de cyclosporines |
US4996193A (en) | 1989-03-03 | 1991-02-26 | The Regents Of The University Of California | Combined topical and systemic method of administration of cyclosporine |
JP2785981B2 (ja) * | 1989-11-20 | 1998-08-13 | 株式会社資生堂 | 乳化組成物 |
AU6785490A (en) | 1989-12-18 | 1991-06-20 | Kraft General Foods, Inc. | Low-saturate edible oils and transesterification methods for production thereof |
IL102236A0 (en) * | 1991-06-27 | 1993-01-14 | Ltt Inst Co Ltd | Topical preparations containing cyclosporin |
JP3065734B2 (ja) * | 1991-08-27 | 2000-07-17 | 昭和電工株式会社 | 桂皮酸誘導体 |
FR2683225B1 (fr) | 1991-10-31 | 1993-12-31 | Gattefosse Sa | Procede pour ameliorer une huile glycerolysee. |
US5206219A (en) | 1991-11-25 | 1993-04-27 | Applied Analytical Industries, Inc. | Oral compositions of proteinaceous medicaments |
GB9208712D0 (en) * | 1992-04-22 | 1992-06-10 | Sandoz Ltd | Pharmaceutical compositions containing cyclosporin derivates |
SG45449A1 (en) * | 1992-05-13 | 1998-01-16 | Sandoz Ltd | Ophthalmic compositions |
-
1993
- 1993-05-07 SG SG1996008974A patent/SG45449A1/en unknown
- 1993-05-07 DE DE69307505T patent/DE69307505T2/de not_active Expired - Lifetime
- 1993-05-07 DK DK93909919.8T patent/DK0642332T3/da active
- 1993-05-07 ES ES93909919T patent/ES2098739T3/es not_active Expired - Lifetime
- 1993-05-07 WO PCT/EP1993/001123 patent/WO1993023010A1/en active IP Right Grant
- 1993-05-07 JP JP51984293A patent/JP3631490B2/ja not_active Expired - Lifetime
- 1993-05-07 AT AT93909919T patent/ATE147619T1/de active
- 1993-05-07 EP EP93909919A patent/EP0642332B1/en not_active Expired - Lifetime
- 1993-05-12 CN CN93107203A patent/CN1074932C/zh not_active Expired - Lifetime
- 1993-06-08 TW TW082104550A patent/TW279801B/zh not_active IP Right Cessation
-
1994
- 1994-11-10 KR KR1019940704017A patent/KR100344083B1/ko not_active IP Right Cessation
-
1996
- 1996-12-17 US US08/767,610 patent/US5951971A/en not_active Expired - Lifetime
-
1997
- 1997-04-01 GR GR970400664T patent/GR3022990T3/el unknown
-
1998
- 1998-04-23 HK HK98103406A patent/HK1004520A1/xx not_active IP Right Cessation
-
2001
- 2001-08-27 US US09/939,967 patent/US6582718B2/en not_active Expired - Fee Related
-
2004
- 2004-09-10 JP JP2004264204A patent/JP2004346085A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
CN1074932C (zh) | 2001-11-21 |
HK1004520A1 (en) | 1998-11-27 |
WO1993023010A1 (en) | 1993-11-25 |
EP0642332A1 (en) | 1995-03-15 |
US6582718B2 (en) | 2003-06-24 |
DE69307505D1 (de) | 1997-02-27 |
JP2004346085A (ja) | 2004-12-09 |
JPH07506579A (ja) | 1995-07-20 |
EP0642332B1 (en) | 1997-01-15 |
US5951971A (en) | 1999-09-14 |
GR3022990T3 (en) | 1997-07-30 |
KR950701515A (ko) | 1995-04-28 |
US20020045601A1 (en) | 2002-04-18 |
CN1084079A (zh) | 1994-03-23 |
KR100344083B1 (ko) | 2002-11-23 |
TW279801B (es) | 1996-07-01 |
DK0642332T3 (da) | 1997-06-16 |
JP3631490B2 (ja) | 2005-03-23 |
ATE147619T1 (de) | 1997-02-15 |
SG45449A1 (en) | 1998-01-16 |
DE69307505T2 (de) | 1997-07-24 |
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