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ES2089070T3 - Material para implante. - Google Patents

Material para implante.

Info

Publication number
ES2089070T3
ES2089070T3 ES91114373T ES91114373T ES2089070T3 ES 2089070 T3 ES2089070 T3 ES 2089070T3 ES 91114373 T ES91114373 T ES 91114373T ES 91114373 T ES91114373 T ES 91114373T ES 2089070 T3 ES2089070 T3 ES 2089070T3
Authority
ES
Spain
Prior art keywords
implant material
bone
hydroxyapatite
implant
fine structure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91114373T
Other languages
English (en)
Inventor
Hans-Jorg Bauer
Bianca Katzenmeier
Matthias Dr Kuntz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Application granted granted Critical
Publication of ES2089070T3 publication Critical patent/ES2089070T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3687Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02Inorganic materials
    • A61L27/12Phosphorus-containing materials, e.g. apatite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3608Bone, e.g. demineralised bone matrix [DBM], bone powder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56Porous materials, e.g. foams or sponges
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005The prosthesis being constructed from a particular material
    • A61F2310/00179Ceramics or ceramic-like structures
    • A61F2310/00293Ceramics or ceramic-like structures containing a phosphorus-containing compound, e.g. apatite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/40Preparation and treatment of biological tissue for implantation, e.g. decellularisation, cross-linking

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Botany (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Inorganic Insulating Materials (AREA)
  • Compositions Of Oxide Ceramics (AREA)
  • Dental Prosthetics (AREA)
  • Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
  • Preparation Of Clay, And Manufacture Of Mixtures Containing Clay Or Cement (AREA)
  • Saccharide Compounds (AREA)
  • Prostheses (AREA)

Abstract

LA INVENCION TRATA DE UN MATERIAL IMPLANTADO SOBRE LA BASE DE HUESOS NATURALES. SE TRATA DE UN MATERIAL DE CERAMICA SINTERIZADO, DONDE LA ESTRUCTURA FINA Y POROSA, SE PRESENTA GENERALMENTE NO CAMBIADA Y CONSTA DE MAS DEL 99% DE HIDROXILAPATIT.
ES91114373T 1990-09-10 1991-08-27 Material para implante. Expired - Lifetime ES2089070T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4028683A DE4028683A1 (de) 1990-09-10 1990-09-10 Implantatmaterial

Publications (1)

Publication Number Publication Date
ES2089070T3 true ES2089070T3 (es) 1996-10-01

Family

ID=6413960

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91114373T Expired - Lifetime ES2089070T3 (es) 1990-09-10 1991-08-27 Material para implante.

Country Status (18)

Country Link
US (1) US5306302A (es)
EP (1) EP0475189B1 (es)
JP (1) JP3224833B2 (es)
KR (1) KR920006007A (es)
AT (1) ATE139450T1 (es)
AU (1) AU634416B2 (es)
CA (1) CA2050848A1 (es)
CZ (1) CZ280714B6 (es)
DE (2) DE4028683A1 (es)
DK (1) DK0475189T3 (es)
ES (1) ES2089070T3 (es)
GR (1) GR3021047T3 (es)
HU (1) HU207956B (es)
IE (1) IE76140B1 (es)
PT (1) PT98889B (es)
SK (1) SK278671B6 (es)
TW (1) TW211518B (es)
ZA (1) ZA917184B (es)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6033437A (en) 1991-09-30 2000-03-07 Orbital Implant Technology Pegs for orbital implants
US6537574B1 (en) 1992-02-11 2003-03-25 Bioform, Inc. Soft tissue augmentation material
US7968110B2 (en) * 1992-02-11 2011-06-28 Merz Aesthetics, Inc. Tissue augmentation material and method
US7060287B1 (en) * 1992-02-11 2006-06-13 Bioform Inc. Tissue augmentation material and method
SE501288C2 (sv) * 1993-11-30 1995-01-09 Corimed Gmbh Förfarande för framställning av keramiskt implantatmaterial, företrädesvis hydroxylapatit uppvisande keramiskt implantatmaterial
DE4440149A1 (de) * 1994-11-10 1996-05-15 Merck Patent Gmbh Verfahren zur Herstellung von calciumoxidarmer Spongiosa-Knochenkeramik
DE19504955A1 (de) * 1995-02-15 1996-08-22 Merck Patent Gmbh Verfahren zur Herstellung von Spongiosa-Knochenkeramikformkörpern
US20050186673A1 (en) * 1995-02-22 2005-08-25 Ed. Geistlich Soehne Ag Fuer Chemistrie Industrie Collagen carrier of therapeutic genetic material, and method
US5702449A (en) * 1995-06-07 1997-12-30 Danek Medical, Inc. Reinforced porous spinal implants
US6039762A (en) * 1995-06-07 2000-03-21 Sdgi Holdings, Inc. Reinforced bone graft substitutes
DE19543110C2 (de) * 1995-11-18 1998-05-28 Guy Florian Draenert Steriles Knochenmaterial nativen Ursprungs für die Transplantation und Verfahren zur Hitzesterilisierung des Knochenmaterials
US6033438A (en) 1997-06-03 2000-03-07 Sdgi Holdings, Inc. Open intervertebral spacer
US6482584B1 (en) * 1998-11-13 2002-11-19 Regeneration Technologies, Inc. Cyclic implant perfusion cleaning and passivation process
US20050186283A1 (en) 1997-10-10 2005-08-25 Ed. Geistlich Soehne Ag Fuer Chemistrie Industrie Collagen carrier of therapeutic genetic material, and method
US20030180263A1 (en) * 2002-02-21 2003-09-25 Peter Geistlich Resorbable extracellular matrix for reconstruction of bone
US8858981B2 (en) * 1997-10-10 2014-10-14 Ed. Geistlich Soehne Fuer Chemistrie Industrie Bone healing material comprising matrix carrying bone-forming cells
US5899939A (en) * 1998-01-21 1999-05-04 Osteotech, Inc. Bone-derived implant for load-supporting applications
US6063117A (en) * 1998-01-22 2000-05-16 Perry; Arthur C. Porous orbital implant structure
US6986788B2 (en) * 1998-01-30 2006-01-17 Synthes (U.S.A.) Intervertebral allograft spacer
US6123731A (en) * 1998-02-06 2000-09-26 Osteotech, Inc. Osteoimplant and method for its manufacture
DE19825419C2 (de) * 1998-06-06 2002-09-19 Gerber Thomas Verfahren zur Herstellung eines hochporösen Knochenersatzmaterials sowie dessen Verwendung
EP1100417B1 (en) 1998-08-03 2004-04-07 SYNTHES AG Chur Intervertebral allograft spacer
US6174311B1 (en) * 1998-10-28 2001-01-16 Sdgi Holdings, Inc. Interbody fusion grafts and instrumentation
DE29913200U1 (de) 1999-07-28 1999-09-23 Tutogen Medical GmbH, 91077 Neunkirchen Implantat aus Knochenmaterial
GB9922562D0 (en) * 1999-09-24 1999-11-24 Biocomposites Ltd Implant material
KR100331608B1 (ko) * 1999-11-25 2002-04-09 김정근 동물 뼈를 이용한 골이식 대체재 및 그 제조 방법
US7018416B2 (en) * 2000-07-06 2006-03-28 Zimmer Spine, Inc. Bone implants and methods
AU2002244116A1 (en) * 2001-02-16 2002-09-04 Sulzer Spine-Tech Inc. Bone implants and methods
US8740987B2 (en) * 2001-06-04 2014-06-03 Warsaw Orthopedic, Inc. Tissue-derived mesh for orthopedic regeneration
WO2003026538A1 (en) * 2001-09-27 2003-04-03 Sulzer Spine-Tech Inc. Modular spinal fusion device
EP1893174A2 (en) * 2005-05-10 2008-03-05 Cytophil, Inc. Injectable hydrogels and methods of making and using same
US20070184087A1 (en) 2006-02-06 2007-08-09 Bioform Medical, Inc. Polysaccharide compositions for use in tissue augmentation
CA2649970C (en) * 2006-05-12 2011-10-18 Seoul National University Industry Foundation Method for preparing a prion-free bone grafting substitute
US8043377B2 (en) * 2006-09-02 2011-10-25 Osprey Biomedical, Inc. Implantable intervertebral fusion device
RU2468796C2 (ru) * 2006-09-07 2012-12-10 Эд. Гайстлих Зёне Аг Фюр Хемише Индустри Способ лечения рака костей
EP2114474A4 (en) * 2006-12-08 2013-07-31 Graftoss Ltd MEDICAL PREPARATION
US20090012620A1 (en) * 2007-07-06 2009-01-08 Jim Youssef Implantable Cervical Fusion Device
JP2018002579A (ja) * 2016-12-27 2018-01-11 株式会社ソフセラ リン酸カルシウム焼結体粒子の製造方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5645814A (en) * 1979-09-25 1981-04-25 Kureha Chem Ind Co Ltd Hydroxyapatite, its ceramic material and its manufacture
US4314380A (en) * 1980-09-26 1982-02-09 Koken Co., Ltd. Artificial bone
EP0141004B1 (de) * 1983-10-20 1988-01-07 Oscobal Ag Knochenersatzmaterial auf der Basis natürlicher Knochen
US4778471A (en) * 1986-11-19 1988-10-18 University Of Dayton Zcap ceramics
US4861733A (en) * 1987-02-13 1989-08-29 Interpore International Calcium phosphate bone substitute materials
DE3727606A1 (de) * 1987-08-19 1989-05-03 Aesculap Ag Verfahren zur herstellung eines knochenersatzmaterials
JPH021285A (ja) * 1988-01-11 1990-01-05 Asahi Optical Co Ltd 固着可能な歯科用及び医科用顆粒状骨補填材、その固着方法及び骨補填物
DE3903695A1 (de) * 1989-02-08 1990-08-09 Merck Patent Gmbh Resorbierbare knochenkeramik auf basis von tricalciumphosphat

Also Published As

Publication number Publication date
PT98889B (pt) 1999-01-29
ZA917184B (en) 1992-05-27
TW211518B (es) 1993-08-21
IE76140B1 (en) 1997-10-08
SK278671B6 (en) 1997-12-10
DE59107945D1 (de) 1996-07-25
DK0475189T3 (da) 1996-09-09
HUT59614A (en) 1992-06-29
ATE139450T1 (de) 1996-07-15
CZ280714B6 (cs) 1996-04-17
HU912920D0 (en) 1992-01-28
DE4028683A1 (de) 1992-03-12
US5306302A (en) 1994-04-26
GR3021047T3 (en) 1996-12-31
EP0475189A2 (de) 1992-03-18
EP0475189B1 (de) 1996-06-19
CS274291A3 (en) 1992-03-18
HU207956B (en) 1993-07-28
EP0475189A3 (en) 1993-01-27
KR920006007A (ko) 1992-04-27
CA2050848A1 (en) 1992-03-11
PT98889A (pt) 1992-07-31
JPH04226669A (ja) 1992-08-17
AU634416B2 (en) 1993-02-18
AU8247891A (en) 1992-03-12
JP3224833B2 (ja) 2001-11-05
IE913160A1 (en) 1992-03-11

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