EP2238146A4 - Hemagglutinin polypeptides, and reagents and methods relating thereto - Google Patents
Hemagglutinin polypeptides, and reagents and methods relating theretoInfo
- Publication number
- EP2238146A4 EP2238146A4 EP09701014A EP09701014A EP2238146A4 EP 2238146 A4 EP2238146 A4 EP 2238146A4 EP 09701014 A EP09701014 A EP 09701014A EP 09701014 A EP09701014 A EP 09701014A EP 2238146 A4 EP2238146 A4 EP 2238146A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- reagents
- methods relating
- hemagglutinin polypeptides
- hemagglutinin
- polypeptides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/12—Libraries containing saccharides or polysaccharides, or derivatives thereof
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/08—RNA viruses
- G01N2333/11—Orthomyxoviridae, e.g. influenza virus
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Food Science & Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Animal Behavior & Ethology (AREA)
- Pulmonology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Communicable Diseases (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Oncology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1878308P | 2008-01-03 | 2008-01-03 | |
US11/969,040 US20090081193A1 (en) | 2006-08-14 | 2008-01-03 | Hemagglutinin polypeptides, and reagents and methods relating thereto |
US30112608A | 2008-11-17 | 2008-11-17 | |
PCT/US2009/030058 WO2009089121A2 (en) | 2008-01-03 | 2009-01-02 | Hemagglutinin polypeptides, and reagents and methods relating thereto |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2238146A2 EP2238146A2 (en) | 2010-10-13 |
EP2238146A4 true EP2238146A4 (en) | 2012-03-21 |
Family
ID=40853716
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP09701014A Withdrawn EP2238146A4 (en) | 2008-01-03 | 2009-01-02 | Hemagglutinin polypeptides, and reagents and methods relating thereto |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP2238146A4 (en) |
CA (1) | CA2711334A1 (en) |
WO (1) | WO2009089121A2 (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9533037B2 (en) | 2007-10-16 | 2017-01-03 | Declion Holdings Llc | Methods for designing and preparing vaccines comprising directed sequence polymer compositions via the directed expansion of epitopes |
WO2012040406A2 (en) | 2010-09-21 | 2012-03-29 | Massachusetts Institute Of Technology | Influenza treatment and/or characterization; human-adapted ha polypeptides; vaccines |
SG10201709806VA (en) * | 2010-10-04 | 2017-12-28 | Massachusetts Inst Technology | Hemagglutinin polypeptides, and reagents and methods relating thereto |
SG10201807059QA (en) | 2012-05-10 | 2018-09-27 | Massachusetts Inst Technology | Agents for influenza neutralization |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008073161A2 (en) * | 2006-08-14 | 2008-06-19 | Massachusetts Institute Of Technology | Hemagglutinin polypeptides, and reagents and methods relating thereto |
-
2009
- 2009-01-02 CA CA2711334A patent/CA2711334A1/en not_active Abandoned
- 2009-01-02 WO PCT/US2009/030058 patent/WO2009089121A2/en active Application Filing
- 2009-01-02 EP EP09701014A patent/EP2238146A4/en not_active Withdrawn
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008073161A2 (en) * | 2006-08-14 | 2008-06-19 | Massachusetts Institute Of Technology | Hemagglutinin polypeptides, and reagents and methods relating thereto |
Non-Patent Citations (4)
Title |
---|
AARTHI CHANDRASEKARAN ET AL: "Glycan topology determines human adaptation of avian H5N1 virus hemagglutinin", NATURE BIOTECHNOLOGY, NATURE PUBLISHING GROUP, NEW YORK, NY, US, vol. 26, no. 1, 6 January 2008 (2008-01-06), pages 107 - 113, XP008132307, ISSN: 1087-0156, [retrieved on 20080106], DOI: 10.1038/NBT1375 * |
KUMARI KSHAMA ET AL: "Receptor binding specificity of recent human H3N2 influenza viruses", VIROLOGY JOURNAL, BIOMED CENTRAL, LONDON, GB, vol. 4, no. 1, 9 May 2007 (2007-05-09), pages 42, XP021025487, ISSN: 1743-422X, DOI: 10.1186/1743-422X-4-42 * |
STEVENS JAMES ET AL: "Structure and receptor specificity of the hemagglutinin from an H5N1 influenza virus", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE, WASHINGTON, DC; US, vol. 312, no. 5772, 1 April 2006 (2006-04-01), pages 404 - 410, XP002533276, ISSN: 0036-8075, [retrieved on 20060316], DOI: 10.1126/SCIENCE.1124513 * |
VISWANATHAN KARTHIK ET AL: "Glycans as receptors for influenza pathogenesis", GLYCOCONJUGATE JOURNAL, KLUWER ACADEMIC PUBLISHERS, BO, vol. 27, no. 6, 1 August 2010 (2010-08-01), pages 561 - 570, XP002604175, ISSN: 1573-4986, [retrieved on 20100824], DOI: 10.1007/S10719-010-9303-4 * |
Also Published As
Publication number | Publication date |
---|---|
WO2009089121A2 (en) | 2009-07-16 |
CA2711334A1 (en) | 2009-07-16 |
EP2238146A2 (en) | 2010-10-13 |
WO2009089121A3 (en) | 2009-10-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20100802 |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR |
|
AX | Request for extension of the european patent |
Extension state: AL BA RS |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: SASISEKHARAN, VISWANATHAN Inventor name: RAGURAM, S. Inventor name: SRINIVASAN, ARAVIND Inventor name: RAMAN, RAHUL Inventor name: CHANDRASEKARAN, AARTHI Inventor name: VISWANATHAN, KARTHIK Inventor name: SASISEKHARAN, RAM |
|
DAX | Request for extension of the european patent (deleted) | ||
A4 | Supplementary search report drawn up and despatched |
Effective date: 20120222 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: C07H 21/04 20060101ALI20120216BHEP Ipc: A61K 38/16 20060101ALI20120216BHEP Ipc: C40B 40/12 20060101ALI20120216BHEP Ipc: G01N 33/569 20060101ALI20120216BHEP Ipc: C07K 14/11 20060101AFI20120216BHEP |
|
17Q | First examination report despatched |
Effective date: 20140324 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20141007 |