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EP2097086A4 - Contact lens compositions - Google Patents

Contact lens compositions

Info

Publication number
EP2097086A4
EP2097086A4 EP07827381A EP07827381A EP2097086A4 EP 2097086 A4 EP2097086 A4 EP 2097086A4 EP 07827381 A EP07827381 A EP 07827381A EP 07827381 A EP07827381 A EP 07827381A EP 2097086 A4 EP2097086 A4 EP 2097086A4
Authority
EP
European Patent Office
Prior art keywords
contact lens
lens compositions
compositions
contact
lens
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP07827381A
Other languages
German (de)
French (fr)
Other versions
EP2097086A2 (en
Inventor
Saul Yedgar
Yuval Cohen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Morria Biopharmaceuticals Ltd
Yissum Research Development Co of Hebrew University of Jerusalem
Original Assignee
Morria Biopharmaceuticals Ltd
Yissum Research Development Co of Hebrew University of Jerusalem
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Morria Biopharmaceuticals Ltd, Yissum Research Development Co of Hebrew University of Jerusalem filed Critical Morria Biopharmaceuticals Ltd
Publication of EP2097086A2 publication Critical patent/EP2097086A2/en
Publication of EP2097086A4 publication Critical patent/EP2097086A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/717—Celluloses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/718—Starch or degraded starch, e.g. amylose, amylopectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727—Heparin; Heparan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/543—Lipids, e.g. triglycerides; Polyamines, e.g. spermine or spermidine
    • A61K47/544—Phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
    • G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
    • G02B1/041—Lenses
    • G02B1/043—Contact lenses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Eyeglasses (AREA)
EP07827381A 2006-11-14 2007-11-14 Contact lens compositions Withdrawn EP2097086A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US85870606P 2006-11-14 2006-11-14
US90778507P 2007-04-17 2007-04-17
PCT/IL2007/001408 WO2008059502A2 (en) 2006-11-14 2007-11-14 Contact lens compositions

Publications (2)

Publication Number Publication Date
EP2097086A2 EP2097086A2 (en) 2009-09-09
EP2097086A4 true EP2097086A4 (en) 2012-01-11

Family

ID=44991055

Family Applications (1)

Application Number Title Priority Date Filing Date
EP07827381A Withdrawn EP2097086A4 (en) 2006-11-14 2007-11-14 Contact lens compositions

Country Status (4)

Country Link
US (1) US20080113002A1 (en)
EP (1) EP2097086A4 (en)
AU (1) AU2007320737B2 (en)
WO (1) WO2008059502A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG174026A1 (en) 2006-08-03 2011-09-29 Nitec Pharma Ag Delayed-release glucocorticoid treatment of rheumatoid disease
AU2010207740B2 (en) * 2009-01-26 2016-06-16 Nitec Pharma Ag Delayed-release glucocorticoid treatment of asthma
CA2822261A1 (en) * 2010-12-23 2012-06-28 Laurent Alexandre Method to obtain optical means adapted to a human individual suffering or susceptible to suffer from one or more genetic related eye disorder(s) or disease(s)
EP2803372A1 (en) 2013-05-16 2014-11-19 Universiteit Twente Process for the preparation of an object supporting a lipid bilayer

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5064817A (en) * 1987-10-23 1991-11-12 Yissum Research Development Company Of Hebrew University Of Jerusalem Phospholipase a2 inhibiting compositions and their use
EP1247532A1 (en) * 1999-12-27 2002-10-09 Fuso Pharmaceutical Industries Ltd. Composition promoting lacrimal secretion
JP2003160498A (en) * 2001-11-22 2003-06-03 Seikagaku Kogyo Co Ltd Inhibitor of distension of epithelial cell
US20050203054A1 (en) * 2000-01-10 2005-09-15 Saul Yedgar Use of lipid conjugates in the treatment of diseases
WO2006084275A2 (en) * 2005-02-04 2006-08-10 Auburn University Contact drug delivery system
WO2008063520A1 (en) * 2006-11-13 2008-05-29 Yissum Research Development Company Of The Hebrew University Of Jerusalem Contact lens compositions

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US2976576A (en) * 1956-04-24 1961-03-28 Wichterle Otto Process for producing shaped articles from three-dimensional hydrophilic high polymers
US3220960A (en) * 1960-12-21 1965-11-30 Wichterle Otto Cross-linked hydrophilic polymers and articles made therefrom
US3431046A (en) * 1964-02-14 1969-03-04 Studies Inc Flexible polyethylene corneal contact lens
US3503942A (en) * 1965-10-23 1970-03-31 Maurice Seiderman Hydrophilic plastic contact lens
US3542461A (en) * 1967-11-20 1970-11-24 Du Pont Contact lens having an index of refraction approximating that of human tears
US3621079A (en) * 1968-10-21 1971-11-16 Patent Structures Inc Graft of hydroxyalkyl methacrylate onto polyvinylpyrrolidone
US3532679A (en) * 1969-04-07 1970-10-06 Robert Steckler Hydrogels from cross-linked polymers of n-vinyl lactams and alkyl acrylates
US3639524A (en) * 1969-07-28 1972-02-01 Maurice Seiderman Hydrophilic gel polymer insoluble in water from polyvinylpyrrolidone with n-vinyl-2-pyrrolidone and methacrylic modifier
US3816571A (en) * 1969-11-28 1974-06-11 Warner Lambert Co Fabrication of soft plastic lens
BE759530A (en) * 1969-11-28 1971-04-30 Griffin Lab Inc CONTACT LENS AND ITS MANUFACTURING PROCESS
US3803093A (en) * 1971-02-25 1974-04-09 C Neefe Methyl methacrylate copolymer which may be hydrated
US3940207A (en) * 1971-06-11 1976-02-24 E. I. Du Pont De Nemours And Company Soft, tough low refractive index contact lenses
US3772235A (en) * 1971-10-05 1973-11-13 Union Optics Corp Copolymers and hydrogels of unsaturated heterocyclic compounds
US3758448A (en) * 1971-10-05 1973-09-11 Union Optics Corp Copolymers and hydrogels of unsaturated esters
US4055378A (en) * 1971-12-31 1977-10-25 Agfa-Gevaert Aktiengesellschaft Silicone contact lens with hydrophilic surface treatment
US3948871A (en) * 1972-04-21 1976-04-06 George H. Butterfield And Son Composition for hard type contact lens with wettable surface
US3786034A (en) * 1972-06-23 1974-01-15 Frigitronics Of Conn Inc Polyurethane polymers for use in soft lenses and method of producing soft lenses
US3875211A (en) * 1973-01-22 1975-04-01 Alcolac Inc Process for preparing 2-hydroxyalkylacrylates and 2-hydroxyalkylmethacrylates
US3937680A (en) * 1973-05-29 1976-02-10 Global Vision, Inc. Hydrophilic gel terpolymers from hydrophilic n-vinyl monomers, hydroxyalkyl acrylates or methacrylates and polymerizable unsaturated carboxylic acids
JPS5510050B2 (en) * 1973-08-13 1980-03-13
JPS5337028B2 (en) * 1973-12-11 1978-10-06
JPS543738B2 (en) * 1974-05-27 1979-02-26
US4018853A (en) * 1974-11-21 1977-04-19 Warner-Lambert Company Crosslinked, hydrophilic rods of pyrrolidone-methacrylate graft copolymers
FR2292989A1 (en) * 1974-11-29 1976-06-25 Thomson Csf CONNECTOR FOR OPTICAL FIBER
US4099859A (en) * 1974-12-02 1978-07-11 High Voltage Engineering Corporation Contact lens having a smooth surface layer of a hydrophilic polymer
US4064086A (en) * 1976-07-13 1977-12-20 National Patent Development Corporation Thermoplastic hydrogels
US5034166A (en) * 1988-07-21 1991-07-23 Allergan, Inc. Method of molding a colored contact lens
CA2067211C (en) * 1990-07-24 2004-06-15 Katsukiyo Sakurai Phospholipid- or lipid-linked glycosaminoglycan, process for producing the same and metastasis inhibitor
US5733892A (en) * 1990-07-24 1998-03-31 Seikagaku Corporation Metastasis inhibitor composition comprising a phospholipid-linked glycosaminoglycan and method for inhibiting metastasis employing the same
CA2079444C (en) * 1991-02-14 2004-02-03 Rimona Margalit Binding of recognizing substances to liposomes
JP3714683B2 (en) * 1992-07-30 2005-11-09 生化学工業株式会社 Anti-rheumatic agent
US5788687A (en) * 1994-02-01 1998-08-04 Caphco, Inc Compositions and devices for controlled release of active ingredients
US5719656A (en) * 1995-05-19 1998-02-17 Bowling; Patricia J. Contact lens utilizing stiles-crawford effect
US6071532A (en) * 1996-10-15 2000-06-06 Emory University Synthesis of glycophospholipid and peptide-phospholipid conjugates and uses thereof
US20060189568A1 (en) * 2000-01-10 2006-08-24 Saul Yedgar Use of lipid conjugates in the treatment of infection
US7141552B2 (en) * 2000-01-10 2006-11-28 Yissum Research Development Company Of The Hebrew University Of Jerusalem Use of lipid conjugates in the treatment of diseases
US9040078B2 (en) * 2000-01-10 2015-05-26 Yissum Research Development Company Of The Hebrew University Of Jerusalem Use of lipid conjugates in the treatment of diseases of the nervous system
JP4782966B2 (en) * 2000-01-10 2011-09-28 イッサム・リサーチ・ディベロップメント・カンパニー・オブ・ザ・ヘブルー・ユニバーシティ・オブ・エルサレム・リミテッド Use of lipid conjugates in the treatment of disease
US7772196B2 (en) * 2000-01-10 2010-08-10 Yissum Research Development Company Of The Hebrew University Of Jerusalem Use of lipid conjugates in the treatment of diseases
US7101859B2 (en) * 2000-01-10 2006-09-05 Yissum Research Development Company Of The Hebrew University Of Jerusalem Use of lipid conjugates in the treatment of diseases
US6654460B1 (en) * 2000-10-13 2003-11-25 E. Walter Rodgers High-density telecommunication drawer assembly
US6656460B2 (en) * 2001-11-01 2003-12-02 Yissum Research Development Method and composition for dry eye treatment
AR038926A1 (en) * 2002-03-13 2005-02-02 Novartis Ag MATERIALS WITH MULTIPLE VESICLE LAYER CONTENT

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5064817A (en) * 1987-10-23 1991-11-12 Yissum Research Development Company Of Hebrew University Of Jerusalem Phospholipase a2 inhibiting compositions and their use
EP1247532A1 (en) * 1999-12-27 2002-10-09 Fuso Pharmaceutical Industries Ltd. Composition promoting lacrimal secretion
US20050203054A1 (en) * 2000-01-10 2005-09-15 Saul Yedgar Use of lipid conjugates in the treatment of diseases
JP2003160498A (en) * 2001-11-22 2003-06-03 Seikagaku Kogyo Co Ltd Inhibitor of distension of epithelial cell
WO2006084275A2 (en) * 2005-02-04 2006-08-10 Auburn University Contact drug delivery system
WO2008063520A1 (en) * 2006-11-13 2008-05-29 Yissum Research Development Company Of The Hebrew University Of Jerusalem Contact lens compositions

Also Published As

Publication number Publication date
WO2008059502A2 (en) 2008-05-22
WO2008059502A3 (en) 2009-09-03
AU2007320737B2 (en) 2014-04-03
AU2007320737A1 (en) 2008-05-22
US20080113002A1 (en) 2008-05-15
EP2097086A2 (en) 2009-09-09

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Legal Events

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Ipc: G02C 7/04 20060101AFI20091103BHEP

Ipc: A61K 9/00 20060101ALI20091103BHEP

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A4 Supplementary search report drawn up and despatched

Effective date: 20111209

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