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EP1185266A4 - Amorphous form of fexofenadine hydrochloride - Google Patents

Amorphous form of fexofenadine hydrochloride

Info

Publication number
EP1185266A4
EP1185266A4 EP00927651A EP00927651A EP1185266A4 EP 1185266 A4 EP1185266 A4 EP 1185266A4 EP 00927651 A EP00927651 A EP 00927651A EP 00927651 A EP00927651 A EP 00927651A EP 1185266 A4 EP1185266 A4 EP 1185266A4
Authority
EP
European Patent Office
Prior art keywords
amorphous form
fexofenadine hydrochloride
fexofenadine
hydrochloride
amorphous
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP00927651A
Other languages
German (de)
French (fr)
Other versions
EP1185266A1 (en
Inventor
Naresh Kumar
Chandras Has Khanduri
Mukesh Sharma
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ranbaxy Laboratories Ltd
Original Assignee
Ranbaxy Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Laboratories Ltd filed Critical Ranbaxy Laboratories Ltd
Publication of EP1185266A1 publication Critical patent/EP1185266A1/en
Publication of EP1185266A4 publication Critical patent/EP1185266A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP00927651A 1999-05-25 2000-05-25 Amorphous form of fexofenadine hydrochloride Withdrawn EP1185266A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN776DE1999 IN191492B (en) 1999-05-25 1999-05-25
INDE077699 1999-05-25
PCT/IB2000/000708 WO2000071124A1 (en) 1999-05-25 2000-05-25 Amorphous form of fexofenadine hydrochloride

Publications (2)

Publication Number Publication Date
EP1185266A1 EP1185266A1 (en) 2002-03-13
EP1185266A4 true EP1185266A4 (en) 2002-07-17

Family

ID=11091185

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00927651A Withdrawn EP1185266A4 (en) 1999-05-25 2000-05-25 Amorphous form of fexofenadine hydrochloride

Country Status (4)

Country Link
EP (1) EP1185266A4 (en)
AU (1) AU4604000A (en)
IN (1) IN191492B (en)
WO (1) WO2000071124A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6613906B1 (en) 2000-06-06 2003-09-02 Geneva Pharmaceuticals, Inc. Crystal modification
CH695216A5 (en) 2001-02-23 2006-01-31 Cilag Ag A method for manufacturing a non-hydrated salt of a piperidine derivative and a novel crystalline form thus obtainable of such a salt.
US20020177608A1 (en) * 2001-04-09 2002-11-28 Ben-Zion Dolitzky Polymorphs of fexofenadine hydrochloride
EP1399422A2 (en) * 2001-06-18 2004-03-24 Dr. Reddy's Laboratories Ltd. Novel crystalline forms of 4-[4-[4-(hydroxydiphenylmethyl)-1-piperidinyl] -1-hydroxybutyl] -a,a-dimethylbenzene acetic acid and its hydrochloride
US20040044038A1 (en) 2002-06-10 2004-03-04 Barnaba Krochmal Polymorphic form XVI of fexofenadine hydrochloride
KR20060123772A (en) 2004-06-01 2006-12-04 테바 기오기스제르갸르 자르트쾨렌 뮈쾨되 레스즈베니타르사사그 Process for preparation of amorphous form of a drug
EP2105134A1 (en) 2008-03-24 2009-09-30 Ranbaxy Laboratories Limited Stable amorphous fexofenadine hydrochloride
US9216955B2 (en) 2010-06-15 2015-12-22 Chemelectiva S.R.L. Polymorphic form of Fexofenadine hydrochloride, intermediates and process for its preparation
KR101014010B1 (en) * 2010-12-30 2011-02-14 주식회사 한국에너지관리 Apparatus for mixing air bubble into water

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4562181A (en) * 1982-07-30 1985-12-31 Glaxo Group Limited Amorphous form of cefuroxime ester
EP0297580A1 (en) * 1987-07-01 1989-01-04 E.R. Squibb & Sons, Inc. Amorphous form of aztreonam
WO1995031437A1 (en) * 1994-05-18 1995-11-23 Hoechst Marrion Roussel, Inc. Processes for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudormophs thereof
US5631375A (en) * 1992-04-10 1997-05-20 Merrell Pharmaceuticals, Inc. Process for piperidine derivatives
EP0810224A1 (en) * 1996-05-30 1997-12-03 Asahi Glass Company Ltd. Method of producing amorphous paroxetine hydrochloride
WO1998033789A1 (en) * 1997-02-04 1998-08-06 Sepracor, Inc. Synthesis of terfenadine and derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4285957A (en) * 1979-04-10 1981-08-25 Richardson-Merrell Inc. 1-Piperidine-alkanol derivatives, pharmaceutical compositions thereof, and method of use thereof
US4254129A (en) * 1979-04-10 1981-03-03 Richardson-Merrell Inc. Piperidine derivatives

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4562181A (en) * 1982-07-30 1985-12-31 Glaxo Group Limited Amorphous form of cefuroxime ester
EP0297580A1 (en) * 1987-07-01 1989-01-04 E.R. Squibb & Sons, Inc. Amorphous form of aztreonam
US5631375A (en) * 1992-04-10 1997-05-20 Merrell Pharmaceuticals, Inc. Process for piperidine derivatives
WO1995031437A1 (en) * 1994-05-18 1995-11-23 Hoechst Marrion Roussel, Inc. Processes for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudormophs thereof
EP0810224A1 (en) * 1996-05-30 1997-12-03 Asahi Glass Company Ltd. Method of producing amorphous paroxetine hydrochloride
WO1998033789A1 (en) * 1997-02-04 1998-08-06 Sepracor, Inc. Synthesis of terfenadine and derivatives

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO0071124A1 *

Also Published As

Publication number Publication date
WO2000071124A1 (en) 2000-11-30
AU4604000A (en) 2000-12-12
IN191492B (en) 2003-12-06
EP1185266A1 (en) 2002-03-13

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Legal Events

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