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EP1155115A4 - Method of modifying cytotoxic cells and uses thereof - Google Patents

Method of modifying cytotoxic cells and uses thereof

Info

Publication number
EP1155115A4
EP1155115A4 EP00911919A EP00911919A EP1155115A4 EP 1155115 A4 EP1155115 A4 EP 1155115A4 EP 00911919 A EP00911919 A EP 00911919A EP 00911919 A EP00911919 A EP 00911919A EP 1155115 A4 EP1155115 A4 EP 1155115A4
Authority
EP
European Patent Office
Prior art keywords
modifying
cytotoxic cells
cytotoxic
cells
modifying cytotoxic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP00911919A
Other languages
German (de)
French (fr)
Other versions
EP1155115A1 (en
Inventor
Daniela Santoli
Giovanni Rovera
Alessandra Cesano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wistar Institute of Anatomy and Biology
Original Assignee
Wistar Institute of Anatomy and Biology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wistar Institute of Anatomy and Biology filed Critical Wistar Institute of Anatomy and Biology
Publication of EP1155115A1 publication Critical patent/EP1155115A1/en
Publication of EP1155115A4 publication Critical patent/EP1155115A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0693—Tumour cells; Cancer cells
    • C12N5/0694—Cells of blood, e.g. leukemia cells, myeloma cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
EP00911919A 1999-02-24 2000-02-23 Method of modifying cytotoxic cells and uses thereof Withdrawn EP1155115A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12148299P 1999-02-24 1999-02-24
US121482P 1999-02-24
PCT/US2000/004548 WO2000050569A1 (en) 1999-02-24 2000-02-23 Method of modifying cytotoxic cells and uses thereof

Publications (2)

Publication Number Publication Date
EP1155115A1 EP1155115A1 (en) 2001-11-21
EP1155115A4 true EP1155115A4 (en) 2002-03-27

Family

ID=22397001

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00911919A Withdrawn EP1155115A4 (en) 1999-02-24 2000-02-23 Method of modifying cytotoxic cells and uses thereof

Country Status (3)

Country Link
EP (1) EP1155115A4 (en)
AU (1) AU3373300A (en)
WO (1) WO2000050569A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201121308D0 (en) 2011-12-12 2012-01-25 Cell Medica Ltd Process
PL2812431T3 (en) 2012-02-09 2020-02-28 Baylor College Of Medicine Pepmixes to generate multiviral ctls with broad specificity
AU2016324479B2 (en) 2015-09-18 2022-12-01 Baylor College Of Medicine Immunogenic antigen identification from a pathogen and correlation to clinical efficacy

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995027722A1 (en) * 1994-04-06 1995-10-19 Immunex Corporation Interleukin-15

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5820856A (en) * 1992-03-30 1998-10-13 The Wistar Institute Of Anatomy And Biology Modified TALL-104 cells to treat cancer
US5683690A (en) * 1992-03-30 1997-11-04 The Wistar Institute Of Anatomy And Biology Modified cytotoxic tall cell line and compositions and methods for manufacture and use thereof as therapeutic reagents for cancer
US5702702A (en) * 1992-03-30 1997-12-30 The Wistar Institute Of Anatomy And Biology Modified cytotoxic tall cell line and compositions and methods for manufacture and use thereof as therapeutic reagents for cancer
AU694430B2 (en) * 1993-05-14 1998-07-23 Wistar Institute Of Anatomy And Biology, The Use of modified tall-104 cells to treat cancer and viral diseases

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995027722A1 (en) * 1994-04-06 1995-10-19 Immunex Corporation Interleukin-15

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CAESON W E ET AL: "INTERLEUKIN (IL) 15 IS A NOVEL CYTOKINE THAT ACTIVATES HUMAN NATURAL KILLER CELLS VIA COMPONENTS OF THE IL-2 RECEPTOR", JOURNAL OF EXPERIMENTAL MEDICINE, TOKYO, JP, vol. 180, no. 4, 1994, pages 1395 - 1403, XP000670920, ISSN: 0022-1007 *
KANEGANE H ET AL: "ACTIVATION OF NAIVE AND MEMORY T CELLS BY INTERLEUKIN-15", BLOOD, W.B. SAUNDERS, PHILADELPHIA, VA, US, vol. 88, no. 1, 1 July 1996 (1996-07-01), pages 230 - 235, XP002036242, ISSN: 0006-4971 *
See also references of WO0050569A1 *

Also Published As

Publication number Publication date
EP1155115A1 (en) 2001-11-21
AU3373300A (en) 2000-09-14
WO2000050569A1 (en) 2000-08-31

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