EG24978A - Fluoro substituted cycloalkanoindoles, compositions containing such compounds and methods of treatment. - Google Patents

Fluoro substituted cycloalkanoindoles, compositions containing such compounds and methods of treatment.

Info

Publication number: EG24978A
Authority: EG; Egypt
Prior art keywords: compounds; treatment; methods; compositions containing; fluoro substituted
Prior art date: 2002-01-24

Application number

EG2003010067A

Other languages

English (en)

Inventor

Carl Berthelette

Nicolas Lachance

Lianhai Li

Claudio Sturino

Zhaoyin Wang

Original Assignee

Merck Frosst Canada Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-01-24

Filing date

2003-01-25

Publication date

2011-04-03

2003-01-25 Application filed by Merck Frosst Canada Inc filed Critical Merck Frosst Canada Inc

2011-04-03 Application granted granted Critical

2011-04-03 Publication of EG24978A publication Critical patent/EG24978A/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P15/06—Antiabortive agents; Labour repressants
- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Pulmonology (AREA)
Diabetes (AREA)
Orthopedic Medicine & Surgery (AREA)
Pain & Pain Management (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Ophthalmology & Optometry (AREA)
Endocrinology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Hematology (AREA)
Reproductive Health (AREA)
Urology & Nephrology (AREA)
Oncology (AREA)
Vascular Medicine (AREA)
Hospice & Palliative Care (AREA)
Anesthesiology (AREA)
Otolaryngology (AREA)
Emergency Medicine (AREA)
Transplantation (AREA)
Obesity (AREA)

EG2003010067A 2002-01-24 2003-01-25 Fluoro substituted cycloalkanoindoles, compositions containing such compounds and methods of treatment. EG24978A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US35138402P	2002-01-24	2002-01-24

Publications (1)

Publication Number	Publication Date
EG24978A true EG24978A (en)	2011-04-03

Family

ID=27613492

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EG2003010067A EG24978A (en)	2002-01-24	2003-01-25	Fluoro substituted cycloalkanoindoles, compositions containing such compounds and methods of treatment.

Country Status (39)

Country	Link
US (6)	US20030158246A1 (es)
EP (3)	EP1470107B1 (es)
JP (2)	JP4008885B2 (es)
KR (2)	KR100859230B1 (es)
CN (3)	CN101092388A (es)
AR (1)	AR038136A1 (es)
AT (1)	ATE414690T1 (es)
AU (1)	AU2003202343B2 (es)
BR (1)	BR0307050A (es)
CA (1)	CA2471952C (es)
CY (3)	CY1108841T1 (es)
DE (2)	DE122009000022I1 (es)
DK (2)	DK1470107T3 (es)
DO (1)	DOP2003000566A (es)
EA (1)	EA006134B1 (es)
EC (1)	ECSP045203A (es)
EG (1)	EG24978A (es)
ES (2)	ES2316717T3 (es)
FR (1)	FR09C0010I2 (es)
GE (1)	GEP20074078B (es)
HR (1)	HRP20040665B1 (es)
IL (3)	IL162825A0 (es)
IS (2)	IS2633B (es)
JO (1)	JO2481B1 (es)
LU (1)	LU91534I2 (es)
MX (1)	MXPA04007167A (es)
MY (1)	MY137040A (es)
NL (1)	NL300377I2 (es)
NO (3)	NO327322B1 (es)
NZ (1)	NZ533786A (es)
PE (1)	PE20030982A1 (es)
PL (1)	PL208527B1 (es)
PT (2)	PT1470107E (es)
RS (2)	RS51672B (es)
SI (2)	SI1470107T1 (es)
TW (1)	TWI259080B (es)
UA (1)	UA75520C2 (es)
WO (1)	WO2003062200A2 (es)
ZA (1)	ZA200404999B (es)

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US20090076117A1 (en) *	2007-09-17	2009-03-19	Protia, Llc	Deuterium-enriched laropiprant
JP2011526281A (ja)	2008-06-24	2011-10-06	アミラファーマシューティカルズ，インク．	プロスタグランジンｄ２受容体のシクロアルカン［ｂ］インドールアンタゴニスト
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Also Published As

Publication number	Publication date
BR0307050A (pt)	2004-10-26
NO2009013I2 (no)	2012-08-27
RS62404A (en)	2006-12-15
KR100859230B1 (ko)	2008-09-18
NO327322B1 (no)	2009-06-08
ECSP045203A (es)	2004-09-28
FR09C0010I2 (es)	2009-12-18
DOP2003000566A (es)	2003-09-15
DK1470107T3 (da)	2009-03-09
ES2316717T3 (es)	2009-04-16
AU2003202343B2 (en)	2007-07-12
CN101851191A (zh)	2010-10-06
PE20030982A1 (es)	2003-11-19
PL370427A1 (en)	2005-05-30
JP2005518413A (ja)	2005-06-23
AR038136A1 (es)	2004-12-29
IL162825A (en)	2010-12-30
ES2391747T3 (es)	2012-11-29
NL300377I1 (nl)	2009-05-06
SI2045241T1 (sl)	2012-11-30
RS51672B (en)	2011-10-31
JO2481B1 (en)	2009-01-20
EA006134B1 (ru)	2005-10-27
MXPA04007167A (es)	2004-10-29
TWI259080B (en)	2006-08-01
US20030158246A1 (en)	2003-08-21
DE122009000022I1 (de)	2009-08-06
UA75520C2 (en)	2006-04-17
JP4008885B2 (ja)	2007-11-14
US20080033028A1 (en)	2008-02-07
DE60324767D1 (de)	2009-01-02
EP2045241B1 (en)	2012-07-04
IS7329A (is)	2004-06-21
MY137040A (en)	2008-12-31
HRP20040665B1 (en)	2012-11-30
EA200400971A1 (ru)	2004-12-30
US20060069148A1 (en)	2006-03-30
IL188844A0 (en)	2009-02-11
CN1902176A (zh)	2007-01-24
NO20071193L (no)	2004-08-24
WO2003062200A2 (en)	2003-07-31
US20050124680A1 (en)	2005-06-09
EP1470107B1 (en)	2008-11-19
DK2045241T3 (da)	2012-10-15
PT1470107E (pt)	2009-01-30
CN101092388A (zh)	2007-12-26
EP2295409B1 (en)	2014-07-02
IS8887A (is)	2010-03-01
WO2003062200A3 (en)	2003-12-04
ATE414690T1 (de)	2008-12-15
NO2009013I1 (no)	2009-06-29
AU2003202343C1 (en)	2003-09-02
CY1113330T1 (el)	2016-06-22
NL300377I2 (nl)	2009-08-03
EP1470107A2 (en)	2004-10-27
TW200302090A (en)	2003-08-01
US7317036B2 (en)	2008-01-08
US7618994B2 (en)	2009-11-17
GEP20074078B (en)	2007-03-26
CY2009004I1 (el)	2009-11-04
FR09C0010I1 (es)	2009-04-17
US20100081696A1 (en)	2010-04-01
RS20100338A (en)	2011-06-30
CA2471952A1 (en)	2003-07-31
KR20070056166A (ko)	2007-05-31
NO20043536L (no)	2004-08-24
SI1470107T1 (sl)	2009-04-30
CA2471952C (en)	2008-04-01
PT2045241E (pt)	2012-09-26
KR20040075109A (ko)	2004-08-26
ZA200404999B (en)	2006-05-31
CY1108841T1 (el)	2011-04-06
CY2009004I2 (el)	2009-11-04
EP2295409A1 (en)	2011-03-16
HRP20040665A2 (en)	2005-04-30
NZ533786A (en)	2006-11-30
PL208527B1 (pl)	2011-05-31
IL162825A0 (en)	2005-11-20
JP2007186521A (ja)	2007-07-26
IS2633B (is)	2010-06-15
LU91534I2 (fr)	2009-04-27
US20120115921A1 (en)	2012-05-10
EP2045241A1 (en)	2009-04-08

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