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EE04293B1 - Stabiilsed lüofiliseeritud ravimvormid - Google Patents

Stabiilsed lüofiliseeritud ravimvormid

Info

Publication number
EE04293B1
EE04293B1 EE9800123A EE9800123A EE04293B1 EE 04293 B1 EE04293 B1 EE 04293B1 EE 9800123 A EE9800123 A EE 9800123A EE 9800123 A EE9800123 A EE 9800123A EE 04293 B1 EE04293 B1 EE 04293B1
Authority
EE
Estonia
Prior art keywords
dosage forms
lyophilized dosage
stable lyophilized
stable
forms
Prior art date
Application number
EE9800123A
Other languages
English (en)
Estonian (et)
Other versions
EE9800123A (et
Inventor
Bouloumie Colette
Breul Thierry
Colliere Laurence
Faure Philippe
Original Assignee
Sanofi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9484220&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EE04293(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi filed Critical Sanofi
Publication of EE9800123A publication Critical patent/EE9800123A/xx
Publication of EE04293B1 publication Critical patent/EE04293B1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
EE9800123A 1995-11-03 1996-10-30 Stabiilsed lüofiliseeritud ravimvormid EE04293B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9513022A FR2740686B1 (fr) 1995-11-03 1995-11-03 Formulation pharmaceutique lyophilisee stable
PCT/FR1996/001706 WO1997017064A1 (fr) 1995-11-03 1996-10-30 Formulation pharmaceutique lyophilisee stable

Publications (2)

Publication Number Publication Date
EE9800123A EE9800123A (et) 1998-10-15
EE04293B1 true EE04293B1 (et) 2004-06-15

Family

ID=9484220

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9800123A EE04293B1 (et) 1995-11-03 1996-10-30 Stabiilsed lüofiliseeritud ravimvormid

Country Status (32)

Country Link
US (1) US6284277B1 (es)
EP (1) EP0858325B1 (es)
JP (1) JP3357376B2 (es)
KR (1) KR100367752B1 (es)
CN (1) CN1124844C (es)
AR (1) AR004255A1 (es)
AT (1) ATE221374T1 (es)
AU (1) AU713383B2 (es)
BR (1) BR9611367A (es)
CA (1) CA2234140C (es)
CZ (1) CZ287178B6 (es)
DE (1) DE69622735T2 (es)
DK (1) DK0858325T3 (es)
EE (1) EE04293B1 (es)
ES (1) ES2180805T3 (es)
FR (1) FR2740686B1 (es)
HK (1) HK1015697A1 (es)
IL (1) IL124214A (es)
IS (1) IS1967B (es)
MX (1) MX9803344A (es)
MY (1) MY116578A (es)
NO (1) NO322582B1 (es)
NZ (1) NZ321616A (es)
PL (1) PL186284B1 (es)
PT (1) PT858325E (es)
RU (1) RU2163801C2 (es)
SK (1) SK283031B6 (es)
TR (1) TR199800782T2 (es)
TW (1) TW442295B (es)
UA (1) UA60297C2 (es)
WO (1) WO1997017064A1 (es)
ZA (1) ZA969176B (es)

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US6197787B1 (en) * 1997-03-03 2001-03-06 Sanofi-Synthelabo Pharmaceutical formulations containing poorly soluble drug substances
JP4939680B2 (ja) * 1997-05-27 2012-05-30 武田薬品工業株式会社 固形製剤
FR2764800B1 (fr) * 1997-06-23 1999-09-10 Sanofi Sa Composition pharmaceutique solide contenant des derives de benzofuranne
SE9702680D0 (sv) * 1997-07-11 1997-07-11 Astra Pharma Prod New formulation
DE19754324A1 (de) * 1997-12-08 1999-06-10 Byk Gulden Lomberg Chem Fab Neue Darreichungsform enthaltend einen säurelabilen Wirkstoff
ES2216351T3 (es) 1997-12-08 2004-10-16 Altana Pharma Ag Nueva forma de supositorio que comprende un compuesto activo labil o acidos.
GB9804013D0 (en) * 1998-02-25 1998-04-22 Sanofi Sa Formulations
FR2781227B1 (fr) 1998-07-20 2002-02-22 Sanofi Sa Procede pour la preparation du sel potassique du lintitript
FR2782455B3 (fr) * 1998-08-20 2000-09-15 Sanofi Sa Composition pharmaceutique injectable a base d'un sel pharmaceutiquement acceptable du clopidogrel ou de ticlopidine
US6898762B2 (en) 1998-08-21 2005-05-24 United Video Properties, Inc. Client-server electronic program guide
FR2787329B1 (fr) * 1998-12-17 2001-02-09 Aventis Pharma Sa Nouvelle application therapeutique des heparines de bas poids moleculaire
WO2000051564A1 (en) * 1999-03-03 2000-09-08 Eli Lilly And Company Echinocandin pharmaceutical formulations containing micelle-forming surfactants
IL145187A0 (en) * 1999-03-03 2002-06-30 Lilly Co Eli Echinocandin/carbohydrate complexes
FR2793685B1 (fr) * 1999-05-19 2001-08-24 Promindus Actions Promotionnel Compositions pharmaceutiques, destinees a l'administration par voie orale de phloroglucinol et leur preparation
FR2805539B1 (fr) * 2000-02-25 2005-06-10 Oreal Compositions de teinture des fibres keratiniques contenant des derives d'indolizine et procede de teinture
US6716884B1 (en) 2000-05-19 2004-04-06 Promindus (Actions Promotionnelles Dans L'industrie Et Le Commerce) Pharmaceutical compositions for oral administration of phloroglucinol and preparation thereof
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AU2002224063A1 (en) * 2000-11-24 2002-06-03 Yamanouchi Pharmaceutical Co..Ltd. Water-soluble liquid internal medicine
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DK1478339T3 (da) 2002-02-22 2008-08-25 Schering Corp Farmaceutiske formuleringer af antineoplastiske midler, specielt temozolomid, fremgangsmåder til fremstilling og anvendelse heraf
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DK1549638T3 (da) 2002-10-03 2008-01-21 Hoffmann La Roche Indol-3-carboxamider som glucokinase (GK) aktivatorer
ES2291722T3 (es) * 2002-12-03 2008-03-01 Hoffmann La Roche Aminoalcoxiindoles como ligandos 5-ht6-receptores para el tratamiento de transtornos del snc.
DE10305984A1 (de) * 2003-02-13 2004-09-02 Helm Ag Salze organischer Säuren mit Clopidogrel und deren Verwendung zur Herstellung phamazeutischer Formulierungen
GB0304636D0 (en) * 2003-02-28 2003-04-02 Britannia Pharmaceuticals Ltd Pharmaceutical composition for nasal delivery
CN100376251C (zh) * 2003-05-07 2008-03-26 卫材R&D管理有限公司 含有甲基维生素b12的冻干制剂及其制备方法
JP2007504177A (ja) * 2003-09-02 2007-03-01 プリヴァ−ラケマ，エー．エス． 医薬組成物、その製造方法及び治療上の使用
CA2550811C (en) * 2003-12-24 2012-05-01 Jane Hirsh Temperature-stable formulations, and methods of development thereof
US20050255161A1 (en) * 2004-05-10 2005-11-17 Servet Buyuktimkin Method for the long term stabilization of labile compounds at room temperature in pharmaceutical preparations containing water
AU2005249794A1 (en) 2004-06-04 2005-12-15 Teva Pharmaceutical Industries, Ltd. Pharmaceutical composition containing irbesartan
US20060275331A1 (en) * 2004-08-31 2006-12-07 Borek Zaludek Pharmaceutical composition, method of manufacturing and therapeutic use thereof
BRPI0517947A (pt) 2004-11-02 2008-10-21 Univ Northwestern composto de piridazina, composições e métodos
JP2006248978A (ja) 2005-03-10 2006-09-21 Mebiopharm Co Ltd 新規なリポソーム製剤
US20070026026A1 (en) * 2005-08-01 2007-02-01 David Delmarre Oral liquid losartan compositions
EP1787641A1 (de) * 2005-11-22 2007-05-23 Helm AG Tazobactam-Piperacillin-Lyophilisat
US20080108664A1 (en) 2005-12-23 2008-05-08 Liu Belle B Solid-state form of AMG 706 and pharmaceutical compositions thereof
WO2007103711A2 (en) * 2006-03-01 2007-09-13 Dr. Reddy's Laboratories Ltd. Polymorphic forms of rimonabant
JP2009539869A (ja) * 2006-06-06 2009-11-19 スレショルド ファーマシューティカルズ インコーポレイティッド グルフォスファミドの単位用量形態
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GB0715285D0 (en) * 2007-08-06 2007-09-12 Britannia Pharmaceuticals Ltd Improvements in or relating to powdered medicaments for nasal delivery
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AU2011252919B2 (en) 2010-05-12 2017-01-19 Melinta Therapeutics, Inc. Tetracycline compositions
US8861919B2 (en) 2011-02-16 2014-10-14 Tyco Electronics Corporation Fiber optic closure
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CN103230371B (zh) * 2012-05-18 2014-07-23 湖北一半天制药有限公司 注射用奥沙利铂冻干制剂的制备方法
WO2018002673A1 (en) 2016-07-01 2018-01-04 N4 Pharma Uk Limited Novel formulations of angiotensin ii receptor antagonists
CN106706785B (zh) * 2016-12-23 2019-02-26 东药集团沈阳施德药业有限公司 一种采用高效液相色谱检测厄贝沙坦氢氯噻嗪片中有关物质的方法
US10149857B2 (en) 2017-03-09 2018-12-11 Ampac Fine Chemicals Llc Lyophilized cyclophosphamide composition and methods of preparation thereof
US11110063B2 (en) 2017-08-25 2021-09-07 MAIA Pharmaceuticals, Inc. Storage stable sincalide formulations
EA202091396A1 (ru) 2017-12-07 2020-09-02 РИВЕН АйПи ХОЛДКО ЭлЭлСи Композиции и способы лечения метаболических состояний
US20230059869A1 (en) 2021-08-03 2023-02-23 Liqmeds Worldwide Limited Oral pharmaceutical solution of clopidogrel
CN114533683B (zh) * 2021-12-23 2023-08-01 李宏 一种注射用腺苷钴胺冻干制剂组合物及其制备方法
TW202339745A (zh) 2022-01-28 2023-10-16 大陸商上海柯君醫藥科技有限公司 抗血小板藥物的藥物組合物及其用途

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FR2719479B1 (fr) * 1994-05-04 1996-07-26 Sanofi Elf Formulation stable lyophilisée comprenant une protéine: kit de dosage.

Also Published As

Publication number Publication date
NO322582B1 (no) 2006-10-30
UA60297C2 (uk) 2003-10-15
EP0858325A1 (fr) 1998-08-19
HK1015697A1 (en) 1999-10-22
ZA969176B (en) 1998-04-30
BR9611367A (pt) 1999-02-23
IS4729A (is) 1998-04-29
ES2180805T3 (es) 2003-02-16
IL124214A (en) 2001-01-28
KR19990067325A (ko) 1999-08-16
RU2163801C2 (ru) 2001-03-10
PL186284B1 (pl) 2003-12-31
ATE221374T1 (de) 2002-08-15
JPH11507945A (ja) 1999-07-13
KR100367752B1 (ko) 2003-03-15
DK0858325T3 (da) 2002-11-25
WO1997017064A1 (fr) 1997-05-15
NZ321616A (en) 1999-04-29
CZ287178B6 (en) 2000-10-11
CA2234140A1 (fr) 1997-05-15
JP3357376B2 (ja) 2002-12-16
DE69622735T2 (de) 2003-04-03
PL326451A1 (en) 1998-09-28
EP0858325B1 (fr) 2002-07-31
CN1203527A (zh) 1998-12-30
PT858325E (pt) 2002-12-31
EE9800123A (et) 1998-10-15
DE69622735D1 (de) 2002-09-05
CZ123198A3 (cs) 1998-07-15
MX9803344A (es) 1998-09-30
AR004255A1 (es) 1998-11-04
CA2234140C (fr) 2004-10-26
US6284277B1 (en) 2001-09-04
FR2740686A1 (fr) 1997-05-09
NO981967D0 (no) 1998-04-30
TR199800782T2 (xx) 1998-09-21
CN1124844C (zh) 2003-10-22
SK283031B6 (sk) 2003-02-04
AU7499096A (en) 1997-05-29
SK52598A3 (en) 1998-10-07
TW442295B (en) 2001-06-23
MY116578A (en) 2004-02-28
FR2740686B1 (fr) 1998-01-16
NO981967L (no) 1998-06-30
IS1967B (is) 2004-12-15
AU713383B2 (en) 1999-12-02

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Legal Events

Date Code Title Description
HC1A Change of owner name
KB4A Valid patent at the end of a year

Effective date: 20041231

KB4A Valid patent at the end of a year

Effective date: 20051231

KB4A Valid patent at the end of a year

Effective date: 20061231

KB4A Valid patent at the end of a year

Effective date: 20071231

KB4A Valid patent at the end of a year

Effective date: 20081231

KB4A Valid patent at the end of a year

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MM4A Lapsed by not paying the annual fees

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