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EA201390929A1 - Антитела к pcsk9 и способы их применения - Google Patents

Антитела к pcsk9 и способы их применения

Info

Publication number
EA201390929A1
EA201390929A1 EA201390929A EA201390929A EA201390929A1 EA 201390929 A1 EA201390929 A1 EA 201390929A1 EA 201390929 A EA201390929 A EA 201390929A EA 201390929 A EA201390929 A EA 201390929A EA 201390929 A1 EA201390929 A1 EA 201390929A1
Authority
EA
Eurasian Patent Office
Prior art keywords
pcsk9
antibodies
methods
application
relates
Prior art date
Application number
EA201390929A
Other languages
English (en)
Inventor
Ян Ву
Сесилия Чиу
Дэниел Кирххофер
Эндрю Питерсон
Ганеш Колумам
Моника Конг Белтран
Пол Моран
Вэй Ли
Original Assignee
Дженентек, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Дженентек, Инк. filed Critical Дженентек, Инк.
Publication of EA201390929A1 publication Critical patent/EA201390929A1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Obesity (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Изобретение относится к антителам к PCSK9 и способам их применения.
EA201390929A 2010-12-22 2011-12-21 Антитела к pcsk9 и способы их применения EA201390929A1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201061426343P 2010-12-22 2010-12-22
US201161477788P 2011-04-21 2011-04-21
PCT/US2011/066593 WO2012088313A1 (en) 2010-12-22 2011-12-21 Anti-pcsk9 antibodies and methods of use

Publications (1)

Publication Number Publication Date
EA201390929A1 true EA201390929A1 (ru) 2013-12-30

Family

ID=45476670

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201390929A EA201390929A1 (ru) 2010-12-22 2011-12-21 Антитела к pcsk9 и способы их применения

Country Status (19)

Country Link
US (1) US20120195910A1 (ru)
EP (1) EP2655419A1 (ru)
JP (1) JP2014511106A (ru)
KR (1) KR20130118925A (ru)
CN (1) CN103261230A (ru)
AR (1) AR084456A1 (ru)
AU (1) AU2011348232A1 (ru)
BR (1) BR112013015687A2 (ru)
CA (1) CA2820953A1 (ru)
CO (1) CO6721041A2 (ru)
CR (1) CR20130336A (ru)
EA (1) EA201390929A1 (ru)
EC (1) ECSP13012786A (ru)
MA (1) MA34818B1 (ru)
MX (1) MX2013007168A (ru)
SG (1) SG191219A1 (ru)
TW (1) TW201307391A (ru)
WO (1) WO2012088313A1 (ru)
ZA (1) ZA201304153B (ru)

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