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EA201170357A1 - Инженерные антитела к il-13: композиции, способы и применение - Google Patents

Инженерные антитела к il-13: композиции, способы и применение

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Publication number
EA201170357A1
EA201170357A1 EA201170357A EA201170357A EA201170357A1 EA 201170357 A1 EA201170357 A1 EA 201170357A1 EA 201170357 A EA201170357 A EA 201170357A EA 201170357 A EA201170357 A EA 201170357A EA 201170357 A1 EA201170357 A1 EA 201170357A1
Authority
EA
Eurasian Patent Office
Prior art keywords
methods
compositions
applications
engineering antibodies
antibodies
Prior art date
Application number
EA201170357A
Other languages
English (en)
Inventor
Роналд В. Свансон
Эллен Чи
Гопалан Рагхунатхан
Шаньжун Чжао
Йохан Франссон
Уэнди Кордье
Хуан К. Альмагро
Лайнус Хиун
Джилл Джайлс-Комар
Кэрин Т. О'Нил
Джилл М. Картон
Хун Мими Чжоу
Алексей В. Тепляков
Ицин Фэн
Original Assignee
Сентокор Орто Байотек Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Сентокор Орто Байотек Инк. filed Critical Сентокор Орто Байотек Инк.
Publication of EA201170357A1 publication Critical patent/EA201170357A1/ru

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
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    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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Abstract

Изобретение относится к инженерным антителам, иммуноспецифичным по отношению к человеческому белку интерлейкина-13 (IL-13) или его фрагменту, а также способам их получения и использования, включая терапевтические показания.
EA201170357A 2008-08-20 2009-08-11 Инженерные антитела к il-13: композиции, способы и применение EA201170357A1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9047208P 2008-08-20 2008-08-20
US9723208P 2008-09-16 2008-09-16
PCT/US2009/053425 WO2010021874A2 (en) 2008-08-20 2009-08-11 Engineered anti-il-13 antibodies, compositions, methods and uses

Publications (1)

Publication Number Publication Date
EA201170357A1 true EA201170357A1 (ru) 2012-05-30

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ID=41707613

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Application Number Title Priority Date Filing Date
EA201170357A EA201170357A1 (ru) 2008-08-20 2009-08-11 Инженерные антитела к il-13: композиции, способы и применение

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US (2) US8399630B2 (ru)
EP (1) EP2328615A2 (ru)
JP (2) JP2012506695A (ru)
KR (1) KR20110043786A (ru)
CN (1) CN102264391A (ru)
AR (1) AR073088A1 (ru)
AU (1) AU2009283008A1 (ru)
BR (1) BRPI0917370A2 (ru)
CA (1) CA2734645A1 (ru)
CO (1) CO6341573A2 (ru)
CR (1) CR20110152A (ru)
EA (1) EA201170357A1 (ru)
EC (1) ECSP11010840A (ru)
IL (1) IL211087A0 (ru)
MX (1) MX2011001909A (ru)
NI (1) NI201100040A (ru)
NZ (1) NZ591098A (ru)
UY (1) UY32060A (ru)
WO (1) WO2010021874A2 (ru)
ZA (1) ZA201102081B (ru)

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* Cited by examiner, † Cited by third party
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US7906102B2 (en) 2001-10-03 2011-03-15 Vanderbilt University Ligands to radiation-induced molecules
US7306925B2 (en) 2001-11-09 2007-12-11 Vanderbilt University Phage antibodies to radiation-inducible neoantigens
US8399630B2 (en) * 2008-08-20 2013-03-19 Centocor Ortho Biotech Inc. Engineered anti-IL-13 antibodies, compositions, methods and uses
GB0904214D0 (en) 2009-03-11 2009-04-22 Ucb Pharma Sa Biological products
WO2011047146A2 (en) * 2009-10-14 2011-04-21 Centocor Ortho Biotech Inc. Methods of affinity maturing antibodies
JOP20210044A1 (ar) 2010-12-30 2017-06-16 Takeda Pharmaceuticals Co الأجسام المضادة لـ cd38
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