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DZ350A1 - Interférons de leucocytes humains hybrides et procédé pour leur préparation microbiologique. - Google Patents

Interférons de leucocytes humains hybrides et procédé pour leur préparation microbiologique.

Info

Publication number
DZ350A1
DZ350A1 DZ816369A DZ816369A DZ350A1 DZ 350 A1 DZ350 A1 DZ 350A1 DZ 816369 A DZ816369 A DZ 816369A DZ 816369 A DZ816369 A DZ 816369A DZ 350 A1 DZ350 A1 DZ 350A1
Authority
DZ
Algeria
Prior art keywords
interferons
hybrid human
human leukocytes
microbiological preparation
host organisms
Prior art date
Application number
DZ816369A
Other languages
English (en)
French (fr)
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/237,388 external-priority patent/US4414150A/en
Priority claimed from US06/305,657 external-priority patent/US4456748A/en
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of DZ350A1 publication Critical patent/DZ350A1/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/555Interferons [IFN]
    • C07K14/56IFN-alpha
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • C12N15/71Expression systems using regulatory sequences derived from the trp-operon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DZ816369A 1980-11-10 1981-11-09 Interférons de leucocytes humains hybrides et procédé pour leur préparation microbiologique. DZ350A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20557980A 1980-11-10 1980-11-10
US06/237,388 US4414150A (en) 1980-11-10 1981-02-23 Hybrid human leukocyte interferons
US06/305,657 US4456748A (en) 1981-02-23 1981-09-25 Hybrid human leukocyte interferons

Publications (1)

Publication Number Publication Date
DZ350A1 true DZ350A1 (fr) 2004-09-13

Family

ID=27394813

Family Applications (1)

Application Number Title Priority Date Filing Date
DZ816369A DZ350A1 (fr) 1980-11-10 1981-11-09 Interférons de leucocytes humains hybrides et procédé pour leur préparation microbiologique.

Country Status (34)

Country Link
EP (1) EP0051873B1 (fi)
JP (1) JP2642291B2 (fi)
KR (1) KR920007439B1 (fi)
AT (1) ATE46718T1 (fi)
AU (1) AU555293B2 (fi)
BR (1) BR8107293A (fi)
CA (2) CA1212915A (fi)
CH (2) CH663032A5 (fi)
DE (2) DE3144469A1 (fi)
DK (1) DK173590B1 (fi)
DO (1) DOP1981004064A (fi)
DZ (1) DZ350A1 (fi)
ES (2) ES506955A0 (fi)
FI (1) FI79550C (fi)
FR (1) FR2493867B1 (fi)
GB (1) GB2090258B (fi)
GR (1) GR81947B (fi)
HK (1) HK51685A (fi)
IE (1) IE51850B1 (fi)
IL (1) IL64243A (fi)
IT (1) IT1169276B (fi)
KE (1) KE3536A (fi)
LU (1) LU83745A1 (fi)
MC (1) MC1424A1 (fi)
MY (2) MY8700710A (fi)
NL (1) NL189092C (fi)
NO (1) NO165201C (fi)
NZ (1) NZ198906A (fi)
PH (1) PH18565A (fi)
PL (1) PL233748A1 (fi)
PT (1) PT73955B (fi)
SE (1) SE460539B (fi)
YU (1) YU46597B (fi)
ZW (1) ZW26981A1 (fi)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH657141A5 (de) * 1980-07-01 1986-08-15 Hoffmann La Roche Dns-sequenzen, rekombinante expressionsvektoren zur mikrobiellen herstellung von human-leukozyten-interferonen und transformierte mikroorganismen.
EP0072541A3 (en) * 1981-08-14 1984-04-18 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Human leukocyte interferons, process for their microbial production, intermediates therefor and compositions containing them
EP0085693A1 (en) * 1981-08-14 1983-08-17 A/S Alfred Benzon Subjects relating to human inteferon-alpha subtype proteins and corresponding antibodies
GB2108510B (en) * 1981-10-03 1984-12-12 Ciba Geigy Ag Dnas, recombinant dnas, hosts containing them, polypeptides and processes for the production thereof
IT1167610B (it) * 1982-01-19 1987-05-13 Cetus Corp Interfreron ibrido multiclasse, composizione farmaceutica che lo contiene e procedimento di produzione
DE3220116A1 (de) * 1982-05-28 1983-12-01 Dr. Karl Thomae Gmbh, 7950 Biberach Mikrobiologisch hergestellte (alpha)- und ss-interferone, dna-sequenzen, die fuer diese interferone codieren, mikroorganismen, die diese genetische information enthalten, und verfahren zu ihrer herstellung
CA1252046A (en) * 1982-11-04 1989-04-04 Martin J. Cline Methods for oncogenic detection
JPS60500574A (ja) * 1983-02-24 1985-04-25 インステイチユト オルガニチエスコゴ シンテザ アカデミイ ナウク ラトビイスコイ エスエスア−ル ヒト白血球インタ−フェロンn及び細菌細胞におけるその製造方法
GB8315980D0 (en) * 1983-06-10 1983-07-13 Biogen Nv Producing hybrid dna sequences
GB8317880D0 (en) * 1983-07-01 1983-08-03 Searle & Co Structure and synthesis of interferons
US4892743A (en) * 1983-12-21 1990-01-09 Schering Corporation Novel hybrid interferon species
EP0146903A3 (en) * 1983-12-19 1987-07-22 Schering Corporation Production of a vector encoding a novel hybrid interferon species
DE3409966A1 (de) * 1984-03-19 1985-09-26 Hoechst Ag, 6230 Frankfurt Gentechnologisches verfahren zur herstellung von human-gammainterferon und mittel zur durchfuehrung dieses verfahrens
JPS6156199A (ja) * 1984-08-27 1986-03-20 Shionogi & Co Ltd 新規ヒトインタ−フエロンα類
EP0173935A1 (en) * 1984-08-31 1986-03-12 University Patents, Inc. Hybrid lymphoblastoid-leukocyte human interferons
DE3434345A1 (de) * 1984-09-19 1986-03-27 Hoechst Ag, 6230 Frankfurt Verwendung von (alpha)-interferonen zur bekaempfung von durchfaellen
EP0194006B1 (en) * 1985-02-01 1992-04-29 Imperial Chemical Industries Plc Analogous interferon polypeptides, process for their preparation and pharmaceutical compositions containing them
EP0205404B1 (en) * 1985-06-11 1992-07-15 Ciba-Geigy Ag Hybrid interferons
EP0240550A4 (en) * 1985-09-26 1989-09-19 Genetics Inst LUNG SURFACE ACTIVE PROTEINS.
US4806347A (en) * 1985-12-11 1989-02-21 Schering Corporation Interferon combinations
EP0490233A1 (de) * 1986-03-10 1992-06-17 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Monoclonale Antikörper gegen BgIII-Hybridinterferone, deren Verwendung und Verfahren zu ihrer Herstellung
DE3607835A1 (de) * 1986-03-10 1987-09-24 Boehringer Ingelheim Int Hybridinterferone, deren verwendung als arzneimittel und als zwischenprodukte zur herstellung von antikoerpern und deren verwendung sowie verfahren zu ihrer herstellung
US4851220A (en) * 1986-11-26 1989-07-25 Schering Corporation Stable oleaginous gel
US4853218A (en) * 1987-02-24 1989-08-01 Schering Corporation Zinc-protamine-alpha interferon complex
EP0331635A3 (en) * 1988-02-29 1990-02-28 The Board of Regents of the University of Texas System Preparations for treating bladder cancer
US5372808A (en) 1990-10-17 1994-12-13 Amgen Inc. Methods and compositions for the treatment of diseases with consensus interferon while reducing side effect
GB2273931A (en) * 1992-09-28 1994-07-06 Unilever Plc Mutant polypeptides
EP0830368A1 (en) 1995-06-07 1998-03-25 Genta Incorporated Novel carbamate-based cationic lipids
TW442492B (en) * 1995-07-26 2001-06-23 Novartis Ag Process for the enrichment of interferon
FR2823220B1 (fr) 2001-04-04 2003-12-12 Genodyssee Nouveaux polynucleotides et polypeptides de l'erythropoietine (epo)
US7314613B2 (en) 2002-11-18 2008-01-01 Maxygen, Inc. Interferon-alpha polypeptides and conjugates
US7318918B2 (en) 2004-05-19 2008-01-15 Maxygen, Inc. Interferon-alpha polypeptides and conjugates
EP1888633A4 (en) 2005-05-18 2010-01-27 Maxygen Inc UNFOLDED INTERFERON ALPHA POLYPEPTIDE

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR73557B (fi) * 1980-01-08 1984-03-15 Biogen Inc

Also Published As

Publication number Publication date
YU265681A (en) 1984-08-31
YU46597B (sh) 1994-01-20
KR920007439B1 (ko) 1992-09-01
MY8700710A (en) 1987-12-31
CH660743A5 (de) 1987-06-15
DOP1981004064A (es) 1988-03-16
NO165201C (no) 1991-01-16
CH663032A5 (de) 1987-11-13
NZ198906A (en) 1985-12-13
PT73955B (en) 1983-11-23
CA1277616C (en) 1990-12-11
SE8106641L (sv) 1982-06-24
FI813539L (fi) 1982-05-11
ES8302778A1 (es) 1983-02-01
NL189092B (nl) 1992-08-03
NL189092C (nl) 1993-01-04
EP0051873B1 (en) 1989-09-27
PT73955A (en) 1981-12-01
FI79550B (fi) 1989-09-29
IE51850B1 (en) 1987-04-15
ATE46718T1 (de) 1989-10-15
IT8124967A0 (it) 1981-11-10
EP0051873A3 (en) 1982-09-22
DK494681A (da) 1982-05-11
ES506955A0 (es) 1983-02-01
GR81947B (fi) 1984-12-12
PH18565A (en) 1985-08-09
SE460539B (sv) 1989-10-23
MC1424A1 (fr) 1982-10-18
DK173590B1 (da) 2001-04-02
AU555293B2 (en) 1986-09-18
GB2090258A (en) 1982-07-07
HK51685A (en) 1985-07-12
IL64243A0 (en) 1982-02-28
ZW26981A1 (en) 1982-06-02
FR2493867B1 (fr) 1986-06-27
DE3177106D1 (en) 1989-11-02
IL64243A (en) 1985-11-29
JP2642291B2 (ja) 1997-08-20
NL8105078A (nl) 1982-06-01
ES512354A0 (es) 1983-03-01
FR2493867A1 (fr) 1982-05-14
GB2090258B (en) 1984-05-02
NO165201B (no) 1990-10-01
FI79550C (fi) 1990-01-10
PL233748A1 (en) 1983-07-18
JPH07308191A (ja) 1995-11-28
IT1169276B (it) 1987-05-27
IE812622L (en) 1982-05-10
LU83745A1 (de) 1983-09-01
CA1212915A (en) 1986-10-21
EP0051873A2 (en) 1982-05-19
MY8800066A (en) 1988-12-31
NO813785L (no) 1982-05-11
DE3144469A1 (de) 1982-09-02
AU7730481A (en) 1982-05-20
KR830007825A (ko) 1983-11-07
ES8304200A1 (es) 1983-03-01
KE3536A (en) 1985-06-07
BR8107293A (pt) 1982-08-03

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